著者

倉田 なおみ 小松 千絵 平藤 彰 森 義明

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.27, no.5, pp.461-472, 2001-10-10 (Released:2011-03-04)

参考文献数

32

被引用文献数

16 21

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Drugs prepared by pharmacist may sometimes clog the nasogastric tubes, gastrostomy tubes or jejunostomy tubes during drug administration. As a result, such drugs were examined regarding their possibility of clogging. Consequently, 11% of the capsulated drugs (89 drugs) could not be used with tubes due to the fact that they did not come in a dispenser that can be used with tubes. In addition, 15% of the drugs clogged the thin tubes (8Fr.). 7% of the fine granules and granules (94 drugs) could not be used with tubes, 10% of them clogged the thin tubes.On the other hand, in order to decrease the amount of loss due to crushing the tablets, as well as to prevent health hazards, the tablets were dispersed in water. Experiments were performed to obtain data on the disintegration of the tablets in the water. As a result, 74% of 514 tablets were found to be appropriate for administration using this method, and this rate was higher than for crushable tablets (53%).The results were complied and the list of the drugs that could be successfully administered by feeding tubes was made. Accordingly, the problems in crushing were solved and tube clogging could thus be successfully prevented thus resulting in an improved QOL for the patients.

著者

平藤 彰 酒井 麻里 小出 洋子 日山 邦枝 池田 幸 村山 純一郎

出版者

日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.30, no.1, pp.16-19, 2011-04-01 (Released:2011-06-21)

参考文献数

5

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After implementation of the new GCP, our hospital was staffed by clinical research coordinators (CRC) to smoothly conduct clinical trials of higher quality. At present, two pharmacists, two dental hygienists, and one nurse are working concurrently as CRCs in our hospital. An unique feature of CRC work at our hospital include 1) dental hygienists working as CRCs, and 2) CRCs of different specialities are coordinated on the same trial and contributing according to their specialties, participation of each clinical trial, one by one. Previously, in our hospital, clinical trials for medications had been allocated to nurse CRCs, while dental hygienist CRCs support for clinical trial of medical devices. However, a dental hygienist have participated as a CRC for the first time in a clinical trial for a medication in 2009, a pharmacist CRC cooperated the clinical trial with the dental hygienist CRC, and this trial was successfully completed. We anticipate that dental hygienist CRCs supporting clinical trials in dental practice will play an indispensable role in smoothly conducting clinical trials with high quality. In this report, we will present the current status of CRC work, which has been accomplished by cooperation with pharmacists and dental hygienists.