著者

五味 健二 新津 靖

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集 (ISSN:21879761)

巻号頁・発行日

vol.82, no.838, pp.15-00498, 2016 (Released:2016-06-25)

参考文献数

37

---

Understanding stress or strain distribution or birefringence properties is important for proper industrial application of polymer films. For example, it is very important to control the stress and birefringence distribution in polymer films that are used for liquid crystal displays of PCs or smart phones, etc. for their performance improvement. As another example, it is very important to understand the stress distribution in packaging polymer films for reliability management of the package because the forming accuracy depends on the stress distribution in the films. Photoelastic analysis is suitable to understand stress, strain distribution and birefringence properties on polymer films; however, understanding of the stress-optical or strain-optical coefficients of the polymer is indispensable when using the analyzing method. In this study, the influence of displacement rate, stress orientation and stress history on birefringence properties is measured for polyvinylidene chloride (PVDC) at room temperature as an example of semi-crystalline polymer films. The stress-optical coefficient of PVDC depends on the displacement rate, stress orientation and stress history. On the other hand, the strain-optical coefficient of PVDC is approximately independent of them. These phenomena are explained by the result from the viscosity, polymer chain orientation and strain-induced crystallization in PVDC. There is potential given that strain-optical coefficients for semi-crystalline rubbery polymers are approximately independent of the displacement rate, stress orientation and stress history on some conditions because of the mechanism of the phenomenon.

著者

新津 靖 倉橋 明次

出版者

The Textile Machinery Society of Japan

雑誌

繊維機械學會誌 (ISSN:18838715)

巻号頁・発行日

vol.5, no.4, pp.201-208, 1952

---

研究目的前報で述べた設計理論により、調節ノズル挿入型ダクトを設計し、試作実験を行い、理論と実際の比較、ニューマニーズ・ダクトとしての適否、実用上考慮すべき問題について検討しようとした。研究結果1. ノズル調節ダクトの理論と実際はよく一致し、吸取り圧力は任意の強さの処で均一に分布する。2. 調節ノズルの圧力均一化に対する効果は顕著であり、この設計方式は第3報、第13節で述べたような各種の集合分配管路系に適甫し得ることが実証された。3. 謁節ノズルの存在はフリー・ス流通に対し障害とはならない。4. 量琵に適する円錐形ノズルの提唱と抵抗係数の決定。5. ダクト端のフリース沈積に対する考慮と限界風速の測定。6. 調節ノズルなしダクトも、ニユーマニーズ・ダクトとして実用上葦支えなぐ・構造・工作最も簡易となる。7. シングル・ダクト形式の提唱。

著者

兵頭 洋二 宍戸 清一郎 河村 毅 櫻林 啓 新津 靖雄 二瓶 大 青木 裕次郎 村松 真樹 酒井 謙 相川 厚

出版者

一般社団法人 日本移植学会

雑誌

移植 (ISSN:05787947)

巻号頁・発行日

vol.48, no.1, pp.042-047, 2013-03-10 (Released:2014-10-03)

参考文献数

10

---

【Objective】The purpose of this study was to evaluate pharmacokinetic (Pk) profile of newly developed modified release tacrolimus (MR-TAC) in pediatric kidney transplant recipients.【Methods】According to our current immunosuppressive protocol, tacrolimus (TAC) was initially given and converted to MR-TAC in 13 pediatric patients who received kidney transplantation from April 2010 to April 2011. The switch dose ratio was 1:1, and the 24hour full Pk study was assessed before and after the conversion from TAC to MR-TAC.【Results】The mean total daily dose at baseline upon enrollment was 5.4±3.3 mg. There was no significant correlation between the oral dose and the trough concentration (C0) of TAC/MR-TAC. The consecutive Pk studies revealed no significant difference in the mean time to maximum concentration (Tmax) / maximum concentration (Cmax) and the area under the time-concentration curve (AUC0-24) of both reagents; the mean C0 of MR-TAC was 18% lower than those of TAC. A better correlation between AUC0-24 and C0 was observed in MR-TAC compared to that in TAC (r2=0.912, for MR-TAC; r2>0.555, for TAC). 【Conclusion】In the conversion from TAC to MR-TAC, AUC0-24 was equivalent despite the 18% reduction of C0, even in the pediatric kidney transplant recipients. The trough concentration might be an excellent predictor in the therapeutic drug monitoring of MR-TAC because of its better correlation of C0 and AUC0-24.

著者

新津 靖

出版者

旅順工科大学

巻号頁・発行日

1945

---

博士論文