著者
阿部 皓一
出版者
公益社団法人 日本ビタミン学会
雑誌
ビタミン (ISSN:0006386X)
巻号頁・発行日
vol.94, no.3, pp.166-173, 2020-03-25 (Released:2021-03-31)

Vitamin E is a physiologically essential nutrient and its deficiencies in animals are known as rat fecal resorption, rat hemolysis, chicken muscle dystrophy, chicken dystrophy, and chicken encephalomalacia. Each vitamin E deficiency in animals may connect with vitamin E insufficiencies and disorders in humans as follows: fecal resorption vs. infertility, hemolysis vs. vasodilation, muscle dystrophy vs. sarcopenia, and encephalomalacia vs. dementia. This review pursues the history of vitamin E clinical studies based on the following parts; (1) infertility, (2) vasodilation, (3) brain function, (4) physical activity, (5) liver function, (6) periodontal function, (7) immune response, and (8) non-α-tocopherol function.
著者
阿部 皓一 石橋 恭子 大前 雅彦 河部 靖 勝井 五一郎
出版者
日本ビタミン学会
雑誌
ビタミン (ISSN:0006386X)
巻号頁・発行日
vol.51, no.3, pp.111-117, 1977-03-25
被引用文献数
2

A Method for the determination of ubiquinone homologues (UQ) in serum and liver is described. Serum or liver homogenate was saponified with methanolic alkaline solution after addition of 2,3,6-trimethyl-5-nonaprenyl-1,4-benzoquinone (TQ-9) as an internal standard and then extracted with n-hexane. The n-hexane extract was evaporated under N_2 gas at 30℃, and the residue was dissolved in dioxane. The sample solution was applied to the high-speed liquid chromatography (HSLC) using a Permaphase ODS column and ethanol・water (80 : 20) as a mobile phase. The peaks of UQ and TQ-9 were not disturbed by other fat-soluble substances when an on-line high-sensitive multiple wavelength detector set at 275 nm (absorption maximum of UQ) was used as a detector. The proposed HSLC method was found to be more simple and specific than the other conventional determination methods.