著者

高橋 昌也 新井 克明 本間 真人 鈴木 勝 佐藤 信一 幸田 幸直

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.172-175, 2002-04-10 (Released:2011-03-04)

参考文献数

9

被引用文献数

2 1

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To investigate the description of the expiration date and manufacturing number on the drug packages, “pillow” packages and “heat-seal” packages, the questionnairing was carried out to pharmaceutical companies. Fifty-six drugs consisting of three hundred thirty-seven items, with sales of over 10 billion yen in 1998, were investigated at the corresponding 26 companies. The recovery rate of the questionnaire from the company was 100%, and the answer for all questions was also perfect. Three hundred fourteen items (93%) have had description regarding the manufacturing number and/or the expiration date on the heat-sealed packages. The manufacturing number took precedence over the expiration date. Of 269 pillow packages, 69 items (26%) have had description of manufacturing number and/or expiration date on the pillow package. There were 41 products (12%) that the company did not guarantee an expiration date being described on the box container when the packages were taken out from the box container.As a result, the description of the manufacturing number and expiration date on the packages, “pillow” and “heat-seal”, is still not complete even though the companies guarantee the expiration date when the drugs were stored with these packages. Since the information of the expiration date is necessary for the appropriate management of tablet and capsule products, it is required to describe manufacturing number and expiration date on every drug package including “pillow” and “heat-seal” packages.

著者

高橋 昌也

出版者

一般社団法人情報処理学会

雑誌

情報処理学会研究報告コンピュータと教育(CE) (ISSN:09196072)

巻号頁・発行日

vol.2001, no.40, pp.9-16, 2001-05-12

参考文献数

10

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コンピュータがどのような発展を遂げ、社会でどのように活用されているかを知ることは、大変重要なことである。しかし、内容が非常に豊富で、範囲が広く、かつ高度であるため、これらの内容の全体像を理解することは大変困難である。そこで、本稿では、これらの内容に関して講述すべき具体的な事項について考察することにした。It is very important to study the development and applications of computers in the society. However, since these contents are very abundant and advanced, and their range is very wide, it is very difficult to appreciate the whole figure of these contents. So, in this paper, we consider the concrete items which should be mentioned about them.

著者

高橋 昌也 新井 克明 本間 真人 鈴木 勝 佐藤 信一 幸田 幸直

出版者

日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.172-175, 2002

参考文献数

9

被引用文献数

2 1

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To investigate the description of the expiration date and manufacturing number on the drug packages, "pillow" packages and "heat-seal" packages, the questionnairing was carried out to pharmaceutical companies. Fifty-six drugs consisting of three hundred thirty-seven items, with sales of over 10 billion yen in 1998, were investigated at the corresponding 26 companies. The recovery rate of the questionnaire from the company was 100%, and the answer for all questions was also perfect. Three hundred fourteen items (93%) have had description regarding the manufacturing number and/or the expiration date on the heat-sealed packages. The manufacturing number took precedence over the expiration date. Of 269 pillow packages, 69 items (26%) have had description of manufacturing number and/or expiration date on the pillow package. There were 41 products (12%) that the company did not guarantee an expiration date being described on the box container when the packages were taken out from the box container. As a result, the description of the manufacturing number and expiration date on the packages, "pillow" and "heat-seal", is still not complete even though the companies guarantee the expiration date when the drugs were stored with these packages. Since the information of the expiratioh date is necessary for the appropriate management of tablet and capsule products, it is required to describe manufacturing number and expiration date on every drug package including "pillow" and "heat-seal" packages.

著者

大西 三朗 西原 利治 高橋 昌也

出版者

高知大学

雑誌

基盤研究(C)

巻号頁・発行日

2007

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TRAILレセプターのdeath domainに対する単クローン性抗体は、腫瘍細胞特異的な細胞性免疫を惹起して、腫瘍細胞の排除を行う。しかし、副作用として時に胆管上皮細胞障害を誘発し慢性胆管炎に移行する。同様の免疫応答による慢性胆管肝炎はvanishing bile duct症候群として知られ、移植肝の急性および慢性拒絶反応の表現型である。TRAILレセプターのdeath domainにアミノ酸置換を伴う遺伝子多型がマウス存在することを見いだしたので、この抗原決定基に対する免疫応答が難治性の慢性胆管肝炎vanishing bile duct症候群を惹起する可能性があると考え、RT-PCRを用いて各種マウスstrainのTRAILレセプターのdeath domainにつき、遺伝子配列を決定した。