- 著者
- Takeshi Waki Kento Hani Yoshikazu Tabata Hiroyuki Nakamura
- 出版者
- The Japan Institute of Metals and Materials
- 雑誌
- MATERIALS TRANSACTIONS (ISSN:13459678)
- 巻号頁・発行日
- vol.64, no.2, pp.564-567, 2023-02-01 (Released:2023-01-25)
- 参考文献数
- 12
The La–Co cosubstituted M-type strontium ferrite attracts attention as a base material for high-performance ferrite magnets. It is known that the uniaxial magnetic anisotropy of the material is enhanced by increasing the amount of Co by heat treatment under high oxygen pressure, but there is a problem in obtaining a pure sample. The present study investigated the conditions to obtain a single phase with increased La–Co substitution by heat treatments under several oxygen pressures. A single phase of M-type ferrite was obtained up to x = 0.35 at pO2 = 1 atm, and up to x = 0.65 at pO2 = 10 atm with the composition formula of Sr1−xLaxFe12−xCoxO19. The magnetic anisotropy is enhanced according to the Co concentration in these samples. This Paper was Originally Published in Japanese in J. Jpn. Soc. Powder Powder Metallurgy 69 (2022) 288–292.
- 著者
- Hiroyuki Nakamura Toshihiko Murayama
- 出版者
- The Japanese Pharmacological Society
- 雑誌
- Journal of Pharmacological Sciences (ISSN:13478613)
- 巻号頁・発行日
- vol.124, no.3, pp.307-312, 2014-03-20 (Released:2014-03-18)
- 参考文献数
- 30
- 被引用文献数
- 27 37
The arachidonic acid (AA) cascade is regulated mainly by the actions of two rate-limiting enzymes, phospholipase A2 (PLA2) and inducible cyclooxygenase-2 (COX-2). PLA2 acts to generate AA, which serves as the precursor substrate for COX-2 in the metabolic pathway leading to prostaglandin production. Amongst more than 30 members of the PLA2 family, cytosolic PLA2α (cPLA2α, group IVA) plays a major role in releasing AA from cellular membranes. Sphingolipids are a novel class of bioactive lipids that play key roles in the regulation of several cellular processes including growth, differentiation, inflammatory responses, and apoptosis. Recent studies implicated a regulatory function of sphingolipids in prostaglandin production. Whereas ceramide-1-phosphate and lactosylceramide activate cPLA2α directly, sphingosine-1-phosphate induces COX-2 expression. Sphingomyelin has been shown to inhibit the activity of cPLA2α. In addition, several sphingolipid analogs including a therapeutic agent currently used clinically are also reported to be inhibitors of cPLA2α. This review explores the role of sphingolipids in the regulation of cPLA2α and COX-2.
- 著者
- Sakiko Koshimura Toshio Munesue Hiroyuki Nakamura Manabu Oi
- 出版者
- Japan Brain Science society
- 雑誌
- 脳科学誌 (ISSN:13415301)
- 巻号頁・発行日
- vol.47, pp.50-68, 2017 (Released:2017-11-01)
- 参考文献数
- 12
- 著者
- 真下 知子 張 貞京 中村 博幸 Tomoko MASHIMO Jeongkyong CHANG Hiroyuki NAKAMURA 京都文教短期大学 京都文教短期大学 京都文教大学 Kyoto Bunkyo Junior College Kyoto Bunkyo Junior College Kyoto Bunkyo University
- 出版者
- 京都文教短期大学
- 雑誌
- 京都文教短期大学研究紀要 (ISSN:03895467)
- 巻号頁・発行日
- vol.50, pp.136-146, 2011
保育者-保護者間のコミュニケーションの改善をめざし、保育者養成課程においても現場での学びの礎となる取り組みが必要である。筆者らは、教材開発のための予備調査として、保護者からの相談の場面を設定したシナリオ形式の質問紙によるアンケート調査を実施した。現職の保育者による回答の分析より、保育者の答え方の特色として、1.「傾聴・共感」2.「具体的なアドバイス」3.「保育者として一緒に問題解決にあたる姿勢を示すこと」の3点が見られた。
- 著者
- Sayed Ziauddin Hashami Hiroyuki Nakamura Naoko Ohkama-Ohtsu Katsuhiro Kojima Salem Djedidi Izumi Fukuhara Mohammad Daud Haidari Hitoshi Sekimoto Tadashi Yokoyama
- 出版者
- Japanese Society of Microbial Ecology · The Japanese Society of Soil Microbiology
- 雑誌
- Microbes and Environments (ISSN:13426311)
- 巻号頁・発行日
- vol.34, no.1, pp.64-75, 2019 (Released:2019-03-30)
- 参考文献数
- 35
- 被引用文献数
- 9
Legumes form root nodules and fix atmospheric nitrogen by establishing symbiosis with rhizobia. However, excessive root nodules are harmful to plants because of the resulting overconsumption of energy from photosynthates. The delay of an inoculation of the soybean super-nodulation mutant NOD1–3 with Bradyrhizobium diazoefficiens USDA110T by 5 d after an inoculation with several soil bacteria confirmed that one bacterial group significantly decreased root nodules throughout the study period. Moreover, no significant changes were observed in nitrogen fixation by root nodules between an inoculation with USDA 110T only and co-inoculation treatments. To clarify the potential involvement of PR proteins in the restriction of nodule formation in the plants tested, the relative expression levels of PR-1, PR-2, PR-5, and PDF1.2 in NOD1–3 roots were measured using real-time PCR. One group of soil bacteria (Gr.3), which markedly reduced nodule numbers, significantly induced the expression of PR-1, PR-5 and PDF1.2 genes by day 5 after the inoculation. By days 7, 10, and 20 after the inoculation, the expression levels of PR-2 and PR-5 were lower than those with the uninoculated treatment. Inoculations with this group of soil bacteria resulted in lower root nodule numbers than with other tested soil bacteria exerting weak inhibitory effects on nodulation, and were accompanied by the induction of plant defense-related genes. Thus, PR genes appear to play important roles in the mechanisms that suppresses nodule formation on soybean roots.
- 著者
- Soichiro IKUNO Norihisa FUJITA Yuki KAWAGUCHI Taku ITOH Susumu NAKATA Kota WATANABE Hiroyuki NAKAMURA
- 出版者
- The Japan Society of Plasma Science and Nuclear Fusion Research
- 雑誌
- Plasma and Fusion Research (ISSN:18806821)
- 巻号頁・発行日
- vol.6, pp.2401069, 2011-07-01 (Released:2012-01-23)
- 参考文献数
- 9
- 被引用文献数
- 1 1
The variable preconditioned (VP) Krylov subspace method on multi Graphics Processing Unit (GPU) is numerically investigated. Besides, the linear system obtained by finite element method with an edge element is adopted for the problem. The results of computations show that VP conjugate gradient method on multi GPU demonstrated significant achievement than that of CPU. Especially, VP conjugate gradient method on multi GPU is 4.35 times faster than that of CPU. However, transmission rate between the PC using Gigabit Ethernet is the bottleneck of the performance.