著者

Mari Matsumoto Manabu Sakaguchi Shuhei Okazaki Kazuo Hashikawa Tsutomu Takahashi Masayasu Matsumoto Toshiho Ohtsuki Takeshi Shimazu Toshiki Yoshimine Hideki Mochizuki Kazuo Kitagawa

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-16-0707, (Released:2017-01-31)

参考文献数

18

被引用文献数

1 7

---

Background:In Japan, warfarin treatment at prothrombin time-international normalized ratio (PT-INR) of 1.60–2.60 is recommended for elderly patients with nonvalvular atrial fibrillation (NVAF). But it remains unknown whether PT-INR 1.60–1.99 has a similar effect on stroke severity as a value >2.0. The purpose of this study was to clarify the association between infarct volume and PT-INR levels.Methods and Results:The 180 patients (mean age, 76 years [SD, 10 years], 53% male) selected from 429 consecutive ischemic stroke patients admitted within 48 h of onset between 2004 and 2014 with NVAF were included. We classified them into 4 groups according to their PT-INR values on admission: no warfarin (NW), 129 patients; PT-INR <1.60 (poor control: PC), 29 patients; PT-INR 1.60–1.99 (low-intensity control: LC), 14 patients; and PT-INR ≥2.00 (high-intensity control: HC), 8 patients. Median (interquartile range: IQR) of infarct volume was 55 mL (IQR 14–175) in the NW, 42 mL (IQR 27–170) in the PC, 36 mL (IQR 6–130) in the LC, and 11 mL (IQR 0–39) in the HC groups. The infarct volume of the HC group was significantly smaller than in the other 3 groups, but no difference existed between the LC and PC groups or the LC and NW groups.Conclusions:Warfarin control at PT-INR of 1.60–1.99 is not effective for reducing the severity of ischemic stroke in NVAF patients.

著者

葛西 真記子 松本 麻里 Makiko KASAI Mari MATSUMOTO

出版者

鳴門教育大学

雑誌

鳴門教育大学研究紀要 = Research bulletin of Naruto University of Education (ISSN:18807194)

巻号頁・発行日

vol.25, pp.189-203, 2010-03-03

---

This study was conducted to examine instances of conformity behavior, anxiety, public self?consciousness, and approval motivation in adolescent friendships. First, a conformity behavior scale was constructed based on 6 ifferent scales that measure conformity motivation, conformity tendency, conformity orientation and conformity behavior. The subjects comprised 83 male and 72 female university students. They were exposed to item analysis and factor analysis exercises, and a twenty?four?items conformity behavior scale was developed. Second, the hypothesis that adolescents with high anxiety, high public consciousness and high approval motivation have a tendency to conform to others was tested. A total of 57 items were tested on 123 male and 171 female high school students. The results showed that both the internal conformity factor and the external conformity factor are related to anxiety and approval motivation. Therefore, a part of the hypothesis that says that high school students tend to conform to others because of their anxiety and motivation to secure the approval of others was verified in this study. Some studies, however, showed that conforming behavior causes stress in adolescents. In our conclusion, with the view to releasing adolescents from such stress, we suggested that they practice self?assertive behavior.