著者

Maya Honda Mami Iima Masako Kataoka Yasuhiro Fukushima Rie Ota Akane Ohashi Masakazu Toi Yuji Nakamoto

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.mp.2022-0060, (Released:2022-08-03)

参考文献数

35

被引用文献数

2

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Purpose: To investigate whether intravoxel incoherent motion (IVIM) and/or non-Gaussian diffusion parameters are associated with distant disease-free survival (DDFS) in patients with invasive breast cancer.Methods: From May 2013 to March 2015, 101 patients (mean age 60.0, range 28–88) with invasive breast cancer were evaluated prospectively. IVIM parameters (flowing blood volume fraction [fIVIM] and pseudodiffusion coefficient [D*]) and non-Gaussian diffusion parameters (theoretical apparent diffusion coefficient [ADC] at a b value of 0 s/mm2 [ADC0] and kurtosis [K]) were estimated using a diffusion-weighted imaging series of 16 b values up to 2500 s/mm2. Shifted ADC values (sADC200–1500) and standard ADC values (ADC0–800) were also calculated. The Kaplan–Meier method was used to generate survival analyses for DDFS, which were compared using the log-rank test. Univariable Cox proportional hazards models were used to assess any associations between each parameter and distant metastasis-free survival.Results: The median observation period was 80 months (range, 35–92 months). Among the 101 patients, 12 (11.9%) developed distant metastasis, with a median time to metastasis of 79 months (range, 10–92 months). Kaplan–Meier analysis showed that DDFS was significantly shorter in patients with K > 0.98 than in those with K ≤ 0.98 (P = 0.04). Cox regression analysis showed a marginal statistical association between K and distant metastasis-free survival (P = 0.05).Conclusion: Non-Gaussian diffusion may be associated with prognosis in invasive breast cancer. A higher K may be a marker to help identify patients at an elevated risk of distant metastasis, which could guide subsequent treatment.

著者

Yasuhiro Fukushima Hiromi Hirasawa Yoshito Tsushima

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.72, no.4, pp.349-354, 2022-11-01 (Released:2023-01-27)

参考文献数

9

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Aim: To evaluate the effectiveness of radiation protection training among medical students using X-ray equipment.Methods: Medical students attended a training class in diagnostic radiology. This training class began with a lecture on radiation protection, followed by experiments to measure the radiation dose. At the beginning and end of the training class, participants answered five-choice questions regarding the three principles of external radiation protection and the dose reduction rate of the lead apron. We also asked participants to provide free-text answers regarding what they learned from the training class and then conducted a text-mining analysis.Results: In the question regarding the three principles of external radiation protection, only 86% of students correctly answered “time” before the training class, but almost all respondents answered the question correctly after the training class. Before the training class, 81% of the students answered that the shielding rate of the lead apron was 95%, but after the training class, almost all students answered correctly that the shielding rate was 80%. Text-mining showed a co-occurrence network consisting of 10 subgraphs from the frequently occurring words.Conclusion: Having the students conduct measurement experiments on their own was effective for improving their understanding of radiation protection.

著者

Satoshi Ohara Yosuke Hamada Yoshifumi Terajima Tetsuya Ishida Yasunori Kikuchi Yasuhiro Fukushima Akira Sugimoto

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

pp.FSTR-D-23-00158, (Released:2023-11-09)

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This study investigated the effect of single-boiling crystallization of high-yielding sugarcane on sugar and molasses production on a factory-plant scale compared with triple-boiling crystallization of conventional sugarcane. The sugar extraction at the roll-milling process was similar between high-yielding sugarcane KY01-2044 with high fiber and conventional sugarcane NiF8. The weight of sugar yield per sugarcane decreased by 32.6 % compared with the conventional system, whereas the yield of molasses and bagasse increased by 143.1 % and 11.5 %, respectively. The results indicated that sugar, molasses, and bagasse-derived electricity could increase simultaneously when the yields of high-yielding sugarcane were higher by a factor of 1.5 than conventional levels. Furthermore, A-molasses obtained by a single-boiling crystallization had less coloration and better fermentability and operability than conventional C-molasses. In conclusion, this study showed that combining high-yielding sugarcane and single-boiling crystallization could increase sugar production and generate high-quality molasses suitable for biofuel and bagasse-derived electricity production.