著者

森 靖夫 Yasuo Mori

出版者

同志社法學會

雑誌

同志社法學 = The Doshisha Hogaku (The Doshisha law review) (ISSN:03877612)

巻号頁・発行日

vol.73, no.2, pp.397-455, 2021-07-31

---

資料(Material)

著者

森 靖夫 Yasuo Mori

出版者

同志社法學會

雑誌

同志社法學 = The Doshisha Hogaku (The Doshisha law review) (ISSN:03877612)

巻号頁・発行日

vol.73, no.2, pp.397-455, 2021-07-31

---

資料(Material)

著者

Shigeru Ishida Hanae Morikawa Hiroyuki Watanabe Toshikazu Tsuji Takeshi Sugio Yasuo Mori Toshihiro Miyamoto Satohiro Masuda Koichi Akashi Nobuaki Egashira

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.43, no.3, pp.488-492, 2020-03-01 (Released:2020-03-01)

参考文献数

19

被引用文献数

1

---

The intravenous injection of bendamustine often induces venous irritation, which reduces patients’ QOL. We previously reported that the dilution of the final volume of bendamustine from 250 to 500 mL significantly decreased the incidence of venous irritation. However, the influence of this change on the therapeutic efficacy of bendamustine remains unclear. Therefore, the aim of this study was to evaluate the efficacy and safety profiles of bendamustine at different dilutions of the final volume, comparing with the correspondences of previous studies. Thirty-four patients, who received a total of 161 courses of bendamustine and rituximab chemotherapy, were included in this study. The overall response rate of this regimen was 94.1% in this study, which was comparable to that reported in the BRB study (94.2%, a phase II study of bendamustine plus rituximab therapy in Japanese patients). Additionally, the median progression-free survival was not inferior to that reported in the BRB study. Bendamustine-induced venous irritation was observed in 17.6% of the patients during the first treatment cycle administered at a final volume of 500 mL, and was found to be lower than that observed in the control, where bendamustine was administered at a final volume of 250 mL (85.7%). These results suggest that diluting bendamustine to 500 mL, but not to 250 mL, reduces the incidence of venous irritation without a negative impact on its therapeutic efficacy; thus, this simple strategy may be beneficial to ensure efficacy and safety in patients receiving regimens including bendamustine.

著者

森 靖夫 Yasuo Mori

出版者

同志社法學會

雑誌

同志社法学 = The Doshisha law review (ISSN:03877612)

巻号頁・発行日

vol.69, no.7, pp.2621-2647, 2018-02

---

本稿は、イギリスが日本の産業動員準備をどのように見ていたかをイギリス公文書館の文書を用いて明らかにした。イギリスは世界各国が総力戦に向けた産業動員のための組織づくりを始めていることに着目した。なかでも日本は世界の中でも先んじた国として認識していた。とりわけ1927年に成立した資源局を日本のCIDと評価するなど、日本の国家総動員準備を軍国主義の萌芽と見るどころか、本国との類似点に着目していた。もっとも、日本の準備はイギリスの脅威とはならないと判断していたし、それをもって日本が戦争を企図しているとは少なくとも1937年までは考えていなかった。This paper examines British intelligence and perception of Japan's industrial mobilization from 1918 to 1937 mainly analysing the reports from British military attaché. It shows that British military perceives Japan as an advanced country in industrial mobilization. In other words, it means that they didn't regard Japan's preparation for 'Kokka Sodoin (general mobilization)' as the signs of militarism. Moreover, they saw Shigenkyoku (Resources Bureau) established in 1927 as 'Japan's C.I.D' and thought Japan's plans for industrial mobilization didn't threat to British interests in East Asia until 1937.瀬川晃教授古稀記念論集第一部(I)