著者

Yasuki Uchida Mitsuru Motoyoshi Yasuhiro Namura Noriyoshi Shimizu

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.59, no.2, pp.257-262, 2017 (Released:2017-06-22)

参考文献数

29

被引用文献数

5

---

This study investigated guidelines for placement of monocortical screws in the mandible, particularly the mandibular canal. In this study of 35 patients, we used cone-beam computed tomography to determine the distance from the alveolar crest to the superior border of the mandibular canal (DMC) and the shortest distance from the buccal and lingual cortex to the mandibular canal (attaining distance) in the areas between premolars (premolar area), between the second premolar and first molar (middle area), and between the first and second molars (molar area). The DMC values for these areas were 16.55, 18.94, and 16.58 mm, respectively, and were similar in adults and adolescents. When the attaining distance was 8 mm, the heights on the buccal and lingual sides of the areas were 9 and 16.6 mm, 13.7 and 14.7 mm, and 15.3 and 12 mm, respectively. Risk of proximity to the mandibular canal should be considered at above heights or greater when an orthodontic anchorage device (OAD) 8 mm in length is placed. Careful attention is needed for placements on lingual side in adolescents. By reducing the OAD length to 6 mm, placement safety increases in all areas except the premolar area, especially on the buccal side.

著者

Tadashi Saigusa Yuri Aono John L. Waddington

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.59, no.2, pp.195-200, 2017 (Released:2017-06-22)

参考文献数

29

被引用文献数

14

---

The nucleus accumbens is a terminal area of the mesolimbic dopaminergic system that arises in the ventral tegmental area. Opioids are thought to enhance dopaminergic activity in the nucleus accumbens by activating δ- and μ-opioid receptors in the ventral tegmental area. However, δ- and μ-opioid receptor agonists increase extracellular levels of accumbal dopamine when infused directly into the nucleus accumbens of rats. Therefore, the roles of δ- and μ-opioid receptors in regulation of accumbal dopaminergic neural activity have been analyzed by using δ- and μ-opioid receptor ligands. This review describes the mechanisms underlying the stimulatory effects on accumbal dopamine efflux, which are induced by local administration of δ- and μ-opioid receptor agonists into the nucleus accumbens of freely moving rats. The focus of this article is neurochemical studies that use in vivo microdialysis techniques. Taken together, the in vivo neurochemical evidence from these studies indicates that δ- and μ-opioid receptor agonists increase accumbal dopamine efflux by activating naloxone-sensitive opioid receptors, and by mechanisms independent of naloxone-sensitive opioid receptors, in the nucleus accumbens.

著者

Koichi Iwata Ayano Katagiri Masamichi Shinoda

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.59, no.2, pp.173-175, 2017 (Released:2017-06-22)

参考文献数

26

被引用文献数

23

---

Excitability of neurons in the trigeminal ganglion (TG), trigeminal spinal subnucleus caudalis (Vc), and upper cervical spinal cord (C1-C2) is greatly enhanced after orofacial inflammation and trigeminal nerve injury, and TG, Vc, and C1-C2 neurons remain sensitized long after such episodes. Sensitized neurons generate various molecules, which are released from nociceptive neurons in these areas and are involved in modulating the excitability of TG, Vc, and C1-C2 nociceptive neurons. Hyperexcitable nociceptive neurons also activate satellite glial cells in the TG and microglial cells and astrocytes in the Vc and C1-C2. Glial cell activation spreads throughout the TG, Vc, and C1-C2 and triggers the release of various molecules involved in modulating nociceptive neurons in TG, Vc, and C1-C2 neurons. These findings suggest that functional interaction between neurons and glial cells is critical in persistent orofacial pain associated with orofacial inflammation and trigeminal nerve injury.

著者

Masayuki Kobayashi Eri Horinuki

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.59, no.2, pp.167-171, 2017 (Released:2017-06-22)

参考文献数

67

被引用文献数

19

---

Orthodontic tooth movement is accompanied by inflammatory responses in the periodontal ligament. Chemical mediators such as interleukin-1β have key roles in nociception around teeth. Such nociceptive inputs to the periodontal ligament continue for several days and potentially induce plastic changes in higher brain regions, including the cerebral cortex. This review summarizes research on orthodontic treatment-induced modulation of neural activities in the central nervous system. Furthermore, we describe our recent findings on the spatiotemporal effects of orthodontic treatment in the somatosensory and insular cortices.

著者

Steffen Mickenautsch

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.59, no.2, pp.263-272, 2017 (Released:2017-06-22)

参考文献数

27

被引用文献数

3

---

Fissure sealant retention is traditionally considered as a proxy measure for caries prevention. This study investigated the logic behind this proposition, and its validity. A logical framework of the proposition was established. The mechanism of caries development was transferred into a Directed acyclic graph, and this was used to investigate the logical framework. The sensitivity and specificity of full sealant retention in the prediction of dental carious lesion development and the number of false positive/false negative prediction rates were computed. The sensitivity/specificity was statistically compared to that of random values. A contradiction in the logical framework was identified. The mean sensitivity/specificity was 37.9% (SD = 27.8%) and 67.6% (SD = 28.4%), respectively. When these values were compared against random values (30.5%, SD = 25.7% and 58.7%, SD = 31.6%), a non-significant sensitivity (P = 0.06) and a borderline higher specificity (P = 0.04) were observed. The overall false prediction rate was 33.7%, with 16.9% and 16.8% false negative and false positive predictions, respectively. The sensitivity/specificity was too low and the false prediction rate was too high to consider retention a valid proxy for caries prevention. The logic behind the investigated proposition is flawed, contradicted by the current empirical evidence, and thus invalid.

著者

根本 晋一

出版者

日本大学歯学部

雑誌

日本大学歯学部紀要 (ISSN:1348818X)

巻号頁・発行日

no.37, pp.53-74, 2009

著者

根本 晋一

出版者

日本大学歯学部

雑誌

日本大学歯学部紀要 (ISSN:1348818X)

巻号頁・発行日

no.36, pp.65-83, 2008

著者

Masao Araki Shunsuke Namaki Toshihiko Amemiya Kunihito Matsumoto Kazuya Honda Yoshiyuki Yonehara Naoyuki Matsumoto Masatake Asano

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.58, no.4, pp.533-537, 2016 (Released:2016-12-23)

参考文献数

32

被引用文献数

3

---

The occurrence of ameloblastic fibro-odontoma (AFO) in the oral region is unusual and accounts for 1-3% of all odontogenic tumors. AFO presents mixed radiopaque patterns within the lesion with diverse findings; therefore, it is important to compare this tumor with other odontogenic tumors that radiographically present with calcified bodies. Herein, we observed the calcification patterns within the lesion in seven AFO cases (five males, two females; mean age, 8.3 years; age range, 4-13 years). Periapical and panoramic radiographs were obtained from all seven cases. Five cases underwent conventional computed tomography (CT) scanning, and one underwent cone beam CT. Classification of the calcifications primarily involved the following two characteristics on the X-rays: appearance and location of the lesions. All seven cases were located in the molar regions of the mandible in association with impacted teeth. The calcification patterns of these AFOs were mixed or inhomogeneous within the lesion with various findings, including complex odontoma-like calcifications. However, the patterns differed between panoramic radiography and CT in some cases. The radiolucent lesions in AFO demonstrated varying calcification patterns and were associated with impacted teeth on the CT images.(J Oral Sci 58, 533-537, 2016)

著者

Norbert Pásztor Krisztina Kárpáti János Szöllősi Márk Keresztúri Zoltan Kozinszky István Gorzó Márta Radnai

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.58, no.2, pp.247-253, 2016 (Released:2016-06-25)

参考文献数

44

被引用文献数

5

---

About 30% of male infertility cases are idiopathic. Previous studies reported a positive correlation between deep periodontal pockets and sperm sub-motility, which suggests that periodontitis might have a role in idiopathic semen abnormality pathospermia. We evaluated correlations between periodontal infection parameters and the results of sperm analysis of men with idiopathic infertility. In this observational study, semen quality and periodontal status were analyzed for 95 otherwise healthy men attending an andrology unit for sperm analysis. Half the men in the sperm pathology and normozoospermia groups (50.8% and 50%, respectively) had poor periodontal status. Among the 95 participants, 38% had oligozoospermia, 28% had asthenozoospermia, 16% had cryptozoospermia, and 15% were classified as normozoospermic. Sperm pathology category was not associated with frequency of deep periodontal pockets or calculus. Bleeding on probing was significantly lower among men with asthenozoospermia than among those with normozoospermia. Poor periodontal status was not associated with any sperm pathology category or parameter. In contrast with previous findings, the present results indicate that pathospermia and poor semen quality are not associated with periodontal infection in men with idiopathic infertility. (J Oral Sci 58, 247-253, 2016)

著者

Dagli Rushabh J. Tadakamadla Santhosh Dhanni Chandrakant Duraiswamy Prabu Kulkarni Suhas

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.50, no.3, pp.267-272, 2008

被引用文献数

1 36

---

The aim of the present study was to evaluate the oral health attitudes and behavior of undergraduate dental students in India according to age, sex and level of dental education, and to compare it with those of other countries with different socioeconomic conditions. A self-administered questionnaire based on the Hiroshima University – Dental Behavior Inventory (HU-DBI) was distributed among 372 dental students at Darshan Dental College and Hospital (DDCH). The response rate was 75.8% with 44% males and 56% females. The mean HU-DBI score showed a significant relationship (<I>P</I> < 0.05) with age by one way-analysis of variance (ANOVA). The students were considerably concerned about the appearance of their teeth and gums and halitosis. The total mean score was not markedly higher in the clinical years (years 3 and 4) than in the non-clinical years (years 1 and 2), indicating that the students were almost equally aware. Although there were no statistically significant differences in gender and academic year for the mean score of HU-DBI, the present study showed that dental students in India generally had poorer oral health awareness compared to several other countries. The oral health behavior of Indian dental students has to be improved in order to serve as a positive model for their patients, family, and friends. (J. Oral Sci. 50, 267-272, 2008)

著者

Taiichi Kitano Yoshikazu Mikami Takashi Iwase Masatake Asano Kazuo Komiyama

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.58, no.2, pp.163-169, 2016 (Released:2016-06-25)

参考文献数

24

被引用文献数

10

---

Porphyromonas gingivalis is important in the development of marginal periodontitis. However, the precise role and localization of P. gingivalis in chronic periapical periodontitis remain unclear. Thus, methods that can detect P. gingivalis in formalin-fixed and paraffin-embedded (FFPE) tissue samples are needed. We assessed a technique combining loop-mediated isothermal amplification (LAMP) with PCR (PCR-LAMP) for detection of P. gingivalis, using 110 FFPE tissue samples of chronic apical periodontitis. PCR-LAMP specifically detected P. gingivalis with high sensitivity in FFPE tissue samples, and the sensitivity of the technique was higher than that of PCR or LAMP alone. The results of immunohistochemistry (IHC) confirmed the specificity of PCR-LAMP. IHC showed that P. gingivalis was localized in a granular layer of chronic apical periodontitis, a region that correlated with the localization of macrophages. This is the first study to describe the localization of P. gingivalis in human periapical periodontitis. In conclusion, PCR-LAMP was an effective tool for detecting P. gingivalis in periapical periodontitis. In addition, IHC results improve our understanding of the role of P. gingivalis in the progression of periapical periodontitis. (J Oral Sci 58, 163-169, 2016)

著者

Naoto Yoshinuma Ryosuke Koshi Kazuhiro Kawamoto Masataka Idesawa Naoyuki Sugano Shuichi Sato

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.58, no.1, pp.137-140, 2016 (Released:2016-03-26)

参考文献数

10

被引用文献数

3

---

This case report describes the clinical efficacy of treatment with basic fibroblast growth factor (FGF-2) for periodontal regeneration. A patient with aggressive periodontitis participated in a clinical trial involving administration of 0.3% FGF-2 in comparison with a placebo control. To evaluate the efficacy of FGF-2, standardized radiographs were taken before surgery and at 12, 24, and 36 weeks after FGF-2 treatment. The rate of increase in alveolar bone height was 86.9% at 36 weeks. The 6-year postoperative radiograph showed significant development of alveolar bone in comparison with the first visit. FGF-2 treatment may be effective for periodontal regeneration in cases of aggressive periodontitis. (J Oral Sci 58, 137-140, 2016)

著者

Osamu Saiki Hiroyasu Koizumi Nobutaka Akazawa Akihisa Kodaira Kentaro Okamura Hideo Matsumura

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.58, no.1, pp.117-123, 2016 (Released:2016-03-26)

参考文献数

20

被引用文献数

10

---

This study compared the wear characteristics of a heat-pressed lithium disilicate ceramic material opposed to feldspathic porcelain, a lithium disilicate glass ceramic, and zirconia materials. Ceramic plate specimens were prepared from feldspathic porcelain (EX-3 nA1B), lithium disilicate glass ceramics (e.max CAD MO1/C14), and zirconia (Katana KT 10) and then ground or polished. Rounded rod specimens were fabricated from heat-pressed lithium disilicate glass ceramic (e.max press LT A3) and then glazed or polished. A sliding wear testing apparatus was used for wear testing. Wear of glazed rods was greater than that of polished rods when they were abraded with ground zirconia, ground porcelain, polished porcelain, or polished lithium disilicate ceramics. For both glazed and polished rods, wear was greater when the rods were abraded with ground plates. The findings indicate that application of a polished surface rather than a glazed surface is recommended for single restorations made of heat-pressed lithium disilicate material. In addition, care must be taken when polishing opposing materials, especially those used in occlusal contact areas. (J Oral Sci 58, 117-123, 2016)

著者

Kunihiko Sawada Dirk Schulze Kunihito Matsumoto Shigenori Hirai Koji Hashimoto Kazuya Honda

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.57, no.4, pp.389-392, 2015 (Released:2015-12-13)

参考文献数

8

被引用文献数

8

---

We describe a rare case of osteochondroma of the coronoid process of mandible accompanied by severe trismus in a 14-year-old Japanese boy. The patient had initially been diagnosed as having internal derangement of the temporomandibular joint (TMJ), and conservative treatment had failed to improve the symptoms. Despite extremely limited TMJ movement, panoramic radiography revealed no abnormality, but magnetic resonance imaging suggested internal derangement of the left TMJ. Five months later, the trismus worsened and computed tomography revealed a bone-like mass confluent with the coronoid process, which was finally diagnosed as osteochondroma. The patient then underwent intra-oral coronoidectomy. (J Oral Sci 57, 389-392, 2015)

著者

Masao Araki Takeshi Kiyosaki Mai Sato Kiyomi Kohinata Kunihito Matsumoto Kazuya Honda

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.57, no.4, pp.373-378, 2015 (Released:2015-12-13)

参考文献数

43

被引用文献数

5

---

We measured the gonial angle (GA) on panoramic radiography (PR) and analyzed the correlation between the GA on PR and lateral cephalometric radiography (LCR). In total, 49 PR films and LCR films from dentate young adults were evaluated. Orthodontists plotted four points (articulare, menton, posterior gonion, and lower gonion) on the PR and carefully traced them. Using a protractor, two radiologists measured the GA on LCR images. A simultaneous experimental study of two dry skulls was performed to compare the GA on LCR and PR. The GA was slightly smaller on the PR of the dry mandible than on the LCR and tended to decrease continuously with magnitude toward the Frankfort horizontal plane. The mean GA was 115.1 ± 5.2° on PR and 122.2 ± 6.4° on the LCR. The values were highly correlated (Pearson product-moment correlation coefficient, 0.801). The GA on PR was nonsignificantly smaller than that measured on LCR. The difference may be due to head position, the inclination angle of the mandibular body, and/or the direction of the incident X-ray beam. (J Oral Sci 57, 373-378, 2015)

著者

佐藤 恵 若林 修一 酒井 秀嗣

出版者

日本大学歯学部

雑誌

日本大学歯学部紀要 (ISSN:1348818X)

巻号頁・発行日

no.37, pp.21-29, 2009

被引用文献数

2

著者

Kunihito Matsumoto Souksavanh Vongsa Ichiro Nakajima Ken-ichiro Ejima Kiyomi Kohinata Toshihiro Suzuki Shigeharu Hosono Hirofumi Aboshi Fumiyuki Kuwata Kichibee Otsuka

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.57, no.3, pp.235-239, 2015 (Released:2015-09-15)

参考文献数

12

被引用文献数

2 4

---

As part of quality assessment of a teleradiology program we evaluated the validity of patient information received, the quality of panoramic radiography imaging in Laos, and the ability of a Laotian radiologist to detect temporomandibular joint abnormalities. The amount of patient information gathered from 2,021 scans of panoramic radiographs was evaluated by triage before image diagnosis. Among the radiographs from 2,021 patients, primary triage indicated that there was insufficient information for 794 (39.3%) patients. Secondary triage to assess imaging failure included 1,227 radiographs, four of which were excluded from imaging diagnosis because of unacceptable image flaws. In total, 2,446 joints from 1,223 radiographs were evaluated for temporomandibular joint abnormalities in order to compare the image interpretation abilities of Laotian and Japanese radiologists. The kappa coefficient was 0.836 (P < 0.01) for the agreement between the two observers in detecting temporomandibular joint abnormalities on radiographs. We conclude that additional efforts are needed in order to overcome the challenges of maintaining quality in imaging techniques and diagnoses in Laos. (J Oral Sci 57, 235-239, 2015)

著者

Tamotsu Tsurumachi Yoriyuki Hirano Akiko Hira Yasuyo Aida Bunnai Ogiso

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.57, no.2, pp.157-160, 2015 (Released:2015-06-10)

参考文献数

10

被引用文献数

7

---

When a primary tooth sustains a traumatic injury, development of the permanent tooth can be disturbed, leading to various malformations. This case report details the 7-year follow-up of a developmental anomaly of a central mandibular incisor in a 10-year-old Japanese girl with a history of dental trauma that had occurred at age 4. The trauma had resulted in unusual crown dilaceration in the permanent successor, which exhibited a discoloured and abnormal crown morphology. Radiographic examination revealed crown dilaceration of the tooth, which had a curved root canal. (J Oral Sci 57, 157-160, 2015)

著者

Katsuyoshi Tsunori

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.57, no.2, pp.131-136, 2015 (Released:2015-06-10)

参考文献数

16

被引用文献数

1 11

---

This study investigated the effects of administration of parathyroid hormone (PTH) at different dosages and schedules on bone regeneration in critical-size bone defects in rat calvariae. After calvarial defects had been prepared in 50 rats, they were divided into five treatment groups: 15 µg/kg PTH daily (PTH-15), 35 µg/kg PTH three times per week (PTH-35), 105 µg/kg once per week (PTH-105-1), 105 µg/kg three times per week (PTH-105-3), and controls given vehicle alone. Bone regeneration was evaluated radiographically using micro-computed tomography (micro-CT) or histologically. The amount of newly generated bone in the calvarial defects was found to be significantly greater in the PTH groups than in the control group, and did not differ significantly among the PTH-15, PTH-35, and PTH-105-1 groups, whereas the PTH-105-3 group showed a significantly greater degree of new bone formation than the other PTH groups. It appeared that a higher dose of PTH stimulated a greater degree of bone regeneration in this experimental setting. The present results also suggest that the total dose of PTH administered is significantly related to the amount of bone regenerated within a defined period, indicating that less frequent administration of PTH might be a feasible protocol for bone regeneration therapy. (J Oral Sci 57, 131-136, 2015)

著者

Hiroyasu Kurokawa Toshiki Takamizawa Akitomo Rikuta Keishi Tsubota Masashi Miyazaki

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.57, no.2, pp.101-108, 2015 (Released:2015-06-10)

参考文献数

35

被引用文献数

3 14

---

In this clinical study, we evaluated the 3-year clinical performance of a resin composite containing a surface-prereacted glass ionomer (S-PRG) filler (Beautifil II; Shofu Inc., Kyoto, Japan) placed with a single-step self-etch adhesive (BeautiBond; Shofu Inc.) in posterior restorations. Using modified US Public Health Service criteria, two experienced investigators performed clinical evaluations at the baseline, 6 months, 18 months, and 3 years. Color match, marginal adaptation, anatomical form, surface roughness, marginal discoloration, postoperative sensitivity, and secondary caries were evaluated. After 3 years, 26 patients attended the recall and 31 restorations were evaluated. No postoperative sensitivity or secondary caries was observed at any time point, and no restorations failed during the follow-up period. However, surface roughness, marginal adaptation, and marginal discoloration showed deterioration after 3 years. In conclusion, although some clinical changes were observed, resin composite containing S-PRG filler placed with self-etch adhesive exhibited acceptable clinical behavior in posterior restorations. (J Oral Sci 57, 101-108, 2015)