著者
本間 学 阿部 良治 小此木 丘 佐藤 信 小管 隆夫 三島 章義
出版者
日本細菌学会
雑誌
日本細菌学雑誌 (ISSN:00214930)
巻号頁・発行日
vol.20, no.6, pp.281-289, 1965-06-25 (Released:2009-02-19)
参考文献数
24
被引用文献数
3 3

This paper outlines the natures of Habu snake and Erabu sea snake and properties and actions of their venoms. Moreover was described the effect of tannic acid on the venoms.Habu snake (Trimereserus flavoviridis) is venomous, landinhibiting on the Amami islands and about 150cm long. The victims of Habu snake bite was estimated at 250 to 300 each year. The death rate during recent 7 years was more than 1 per cent. The minimal lethal dosis for mice, weighing 15 to 17g. was about 150γ/0.1ml by intramusculare injection. It was considered that the venom was composed of haemorrhagic, angiotoxic and myolytic factors, which were completly inactivated by heating at 100C for 10 minutes, and heat-stable myolytic factor.Erabu sea snake (Laticauda semifasciata) lives on the coast of Amami Oshima, and has strong fatal venoms. Minimal lethal dosis, in experiments with mice weighing 15 between 17g., was about 6γ/0.1ml by the intramusculare injections. Erabu sea snake venom is considered to have chiefly neurotoxic component which was relatively stable in heating.It was recognized that the toxic activities of the venoms of these different species were inhibited by aqueous solution of tannic acid; a 8.5% solution inactivated lethal and local haemorrhagic activities of 500γ/0.1ml of Habu snake venom, and fatal toxicities of 25γ/0.1ml of Erabu sea snake venom.The above mentioned effect of tannic acid on the venoms may be due to coagulations of the venom and tissue proteins by tannic acid.
著者
三島 章義
出版者
日本衛生動物学会
雑誌
衛生動物 (ISSN:04247086)
巻号頁・発行日
vol.18, no.1, pp.27-31, 1967
被引用文献数
2

1) 名瀬保健所の野外飼育場にハブ30匹を放ち, 時刻別の出現状況を定量的に観察した.1964年4月19日から4月24日の6夜にわたつて観察した結果, ハブの活動は日暮から日の出に行なわれ, 午前1時に活動の頂点のある一峯性の活動消長を示した.活動の消長は, 温度, 湿度とも相関関係が認められた.ハブの日周期はハブ咬傷の時刻消長とは全く平行しておらず, 咬傷発生の要因としては, 人間の活動が重要な因子であることを推定した.2) 野外飼育場でハブ捕獲箱の捕獲率を比較した.捕獲率は箱の形で著しく異なつたが, 誘引のために生きたネズミを入れることは効果のないことを認めた.本研究に際し, 多大の御援助を賜わつた鹿児島県名瀬保健所職員の各位に厚く感謝の意を表する.特に小野継男技師には格別の御協力を得ており, 深く感謝の意を表したい.
著者
本間 学 阿部 良治 小此木 丘 佐藤 信 小管 隆夫 三島 章義
出版者
JAPANESE SOCIETY FOR BACTERIOLOGY
雑誌
日本細菌学雑誌 (ISSN:00214930)
巻号頁・発行日
vol.20, no.6, pp.281-289, 1965
被引用文献数
3

This paper outlines the natures of Habu snake and Erabu sea snake and properties and actions of their venoms. Moreover was described the effect of tannic acid on the venoms.<br>Habu snake (<i>Trimereserus flavoviridis</i>) is venomous, landinhibiting on the Amami islands and about 150cm long. The victims of Habu snake bite was estimated at 250 to 300 each year. The death rate during recent 7 years was more than 1 per cent. The minimal lethal dosis for mice, weighing 15 to 17g. was about 150γ/0.1ml by intramusculare injection. It was considered that the venom was composed of haemorrhagic, angiotoxic and myolytic factors, which were completly inactivated by heating at 100C for 10 minutes, and heat-stable myolytic factor.<br>Erabu sea snake (<i>Laticauda semifasciata</i>) lives on the coast of Amami Oshima, and has strong fatal venoms. Minimal lethal dosis, in experiments with mice weighing 15 between 17g., was about 6γ/0.1ml by the intramusculare injections. Erabu sea snake venom is considered to have chiefly neurotoxic component which was relatively stable in heating.<br>It was recognized that the toxic activities of the venoms of these different species were inhibited by aqueous solution of tannic acid; a 8.5% solution inactivated lethal and local haemorrhagic activities of 500γ/0.1ml of Habu snake venom, and fatal toxicities of 25γ/0.1ml of Erabu sea snake venom.<br>The above mentioned effect of tannic acid on the venoms may be due to coagulations of the venom and tissue proteins by tannic acid.