著者
北原 加奈之 栗原 竜也 田中 広紀 柏原 由佳 縄田 修一 杉田 栄樹 内倉 健 佐々木 忠徳
出版者
一般社団法人 日本薬学教育学会
雑誌
薬学教育 (ISSN:24324124)
巻号頁・発行日
vol.3, pp.2019-002, 2019 (Released:2019-09-19)
参考文献数
15

本邦では標準化された卒後臨床教育プログラムはなく評価方法も確立されていない.そこで,我々は薬剤師レジデントを対象として,英国で開発された臨床能力の評価方法の1つであるCase-based discussion(CbD)を実施し,成長過程を可視化し得るかを検証した.CbDは「薬物治療の必要性評価」等の5項目で評価した.薬剤師レジデント78名と,専門・認定薬剤師(Board certified pharmacists; BCP)5名を対象とした.CbDを実施した結果,5項目すべてのCbDスコアが病棟の経験と共に増加し,4項目が統計学的に有意であった.BCPのCbDスコアは,全項目で最高点の6であった.以上より,CbDは,本邦においても臨床能力の成長プロセスを可視化し,若手薬剤師の教育ツールとして臨床能力の評価に応用できる可能性が示された.今後,多施設を含めた更なる検討が必要である.
著者
川名 真理子 小堀 裕果 中崎 允人 鈴木 正論 永井 淳子 佐々木 忠徳
出版者
一般社団法人日本医薬品情報学会
雑誌
医薬品情報学 (ISSN:13451464)
巻号頁・発行日
vol.15, no.3, pp.105-110, 2013 (Released:2013-12-27)
参考文献数
7

Objective: There are only a few studies evaluating the effects of drug information services on pharmacotherapy.  We, therefore, studied the effects of providing drug information such as the effectiveness and safety of aliskiren on its pharmacotherapeutic efficacy by comparing before versus after drug information provision.Methods: Pharmacists provided drug information such as the effectiveness and safety of aliskiren coadministered with either ACE-I (angiotensin converting enzyme inhibitor) or ARB (angiotensin receptor blocker) to physicians and other healthcare professionals.  We compared the number of patients for whom aliskiren was prescribed, the proportion of diabetic patients taking both aliskiren and ACE-I (or ARB), the proportion of patients with low eGFR (estimated glomerular filtration rate), and the proportion of patients with hyperkalemia and related conditions, before versus after providing the drug information to the healthcare professionals.Results: The number of patients for whom aliskiren was prescribed decreased.  The proportion of patients taking both aliskiren and ACE-I (or ARB) decreased significantly after providing the drug information (p=0.007).  The proportion of diabetic patients taking both aliskiren and ACE-I (or ARB), the proportion of patients with low eGFR, and the proportion of patients with hyperkalemia also decreased, after providing the drug information.Conclusion: This study showed the drug information service to be clinically beneficial, achieving better pharmacotherapy.  Pharmacists should evaluate and provide information on the effectiveness and safety of drugs announced by authorities in a timely manner to achieve optimal patient care.
著者
内藤 結花 前田 真之 長友 安弘 宇賀神 和久 秋間 悦子 田中 道子 時松 一成 佐々木 忠徳
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.142, no.5, pp.527-534, 2022-05-01 (Released:2022-05-01)
参考文献数
18
被引用文献数
2

Antimicrobial stewardship (AS) intervention strategy is a critical process in promoting appropriate antibiotic use, thus preventing unnecessarily prolonged therapy and reducing antimicrobial resistance (AMR). Although limiting unnecessary carbapenem use by AS intervention is speculated to reduce AMR, there is a lack of specific data on the efficacy of AS team (AST) intervention regarding carbapenem-resistant Pseudomonas aeruginosa (CRPA). Consequently, this study aimed to evaluate the impact of our AS strategy on carbapenem use and CRPA. The AS intervention strategy was launched in July 2017 and consisted of daily audits and feedback on carbapenem use. We evaluated the 4-year prescription trend, including the rate of switching to other antimicrobials, and the rate of CRPA and the days of therapy required prior to and after the beginning of the AST intervention. The rate of switching to narrow-spectrum antibiotics and the discontinuation of carbapenem treatment were significantly higher in the pre-intervention period compared with the post-intervention period. (7.0% vs. 14.5%; p<0.001; 54.1% vs. 50.9%; p=0.027). However, there were no significant differences in the rate of CRPA prior to and after the beginning of the AST intervention. Furthermore, there was no correlation found between consumption and resistance rate (Pearson's r=0.123). Our results suggest that it is extremely important for AST to promote de-escalation and reduce unnecessary use, while the combination of process and outcome indicators other than antimicrobial consumption and resistance rate are required for the evaluation of the AS programs.
著者
徳永 愛美 縄田 修一 横山 和彦 稲垣 彩美 瀬尾 晃平 井川 三緒 村川 哲郎 市倉 大輔 峯村 純子 佐々木 忠徳
出版者
日本緩和医療学会
雑誌
Palliative Care Research (ISSN:18805302)
巻号頁・発行日
vol.15, no.4, pp.297-302, 2020 (Released:2020-11-16)
参考文献数
15

がん性疼痛に対してオキシコドン塩酸塩を使用している妊婦症例を経験する機会は極めて少ない.今回,長期にオキシコドン塩酸塩を使用した妊婦を経験した.妊娠経過中は,オキシコドン塩酸塩使用による妊娠経過への悪影響はなく,胎児の発育も順調であった.しかし,児は出生直後に無呼吸発作が出現し,人工呼吸器管理が必要となった.また,新生児薬物離脱症候群に対する薬物治療を必要とした.