著者

佐藤雄治 編訳

出版者

吉岡平助

巻号頁・発行日

1887

著者

藤盛 真樹 鳥谷部 純行 角 伸博 嶋﨑 康相 宮澤 政義 宮手 浩樹 北田 秀昭 佐藤 雄治 三澤 肇 山下 徹郎 中嶋 頼俊 針谷 靖史 小林 一三 西方 聡 太子 芳仁 杉浦 千尋 笠原 和恵 浅香 雄一郎 榊原 典幸 岡田 益彦 柴山 尚大 末次 博 鈴木 豊典 阿部 貴洋 谷村 晶広 工藤 章裕 道念 正樹 川口 泰 野島 正寛 牧野 修治郎

出版者

公益社団法人 日本口腔外科学会

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.68, no.4, pp.168-183, 2022-04-20 (Released:2022-06-20)

参考文献数

38

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Tooth extraction is reported as the main trigger of bisphosphonate (BP) -related osteonecrosis of the jaw (BRONJ). A method to prevent BRONJ has not been scientifically proven. The American Association of Oral and Maxillofacial Surgeons (AAOMS) differs from the International Task Force on Osteonecrosis of the Jaw with regard to the prevention of BRONJ via prophylactic withdrawal before tooth extraction. We performed a multicenter prospective study regarding the development of BRONJ after tooth extraction in BP-treated patients for the purpose of determining factors associated with the frequency of BRONJ. We extracted teeth from patients with a history of current or prior treatment with BP preparations; teeth were extracted using a common treatment protocol. The presence or absence of BRONJ and adverse events were evaluated. A total of 1,323 cases were targeted for this study; 2,371 teeth were extracted. The overall incidence of BRONJ was 1.74%; in the prophylactic withdrawal group it was 1.73%, whereas in the prophylactic non-withdrawal group it was 1.75%. Factors associated with the onset of BRONJ were sex, preparation adaptation classification, oral hygiene state, site of tooth extraction, and Denosumab usage. From analysis that considered the effect of confounding using the propensity score, prophylactic BP withdrawal did not result in a reduction of BRONJ (onset odds ratio with withdrawal: 1.13, 95%CI 0.36-3.57).

著者

石川 義人 樋口 雄介 青村 知幸 八木 正篤 遠藤 光宏 笹原 健児 佐藤 雄治 大屋 高徳 工藤 啓吾

出版者

社団法人 日本口腔外科学会

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.44, no.4, pp.415-417, 1998-04-20 (Released:2011-07-25)

参考文献数

6

被引用文献数

5 5

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We studied the cause, status, and treatment of temporomandibular joint (TMJ) dislocation in patients with psychic and cerebral diseases. These diseases were present in 11 (26.2 %) of 42 patients with TMJ dislocation. Psychic disease included 2 cases of mental retardation and 3 of schizophrenia. Cerebral diseases included 1 case of cerebral infarction, 3 of cerebral hemorrhage, 1 of epilepsy, and 1 of Parkinson disease. There were many old patients among those with cerebral diseases. Convulsions characteristically led to TMJ dislocation. There was prolonged dislocation of the TMJ. A reliable treatment was required in patients with these diseases. Therefore, augmentation of the articular tubercle was indicated. It was suggested that incoordination of the masticatory muscles induced TMJ dislocation. Furthermore, extrapyramidal disorders may have been caused by antipsychotic drugs, Parkinson disease, and cerebrovascular disease; convulsions due to epilepsy may lso have been involved.