著者
仲西 修 山室 宰 亀山 秀一郎 天野 裕治 東 真実 今井 弘貴 梅田 健一郎 椎葉 俊司 西 正勝
出版者
九州歯科学会
雑誌
九州歯科学会雑誌 (ISSN:03686833)
巻号頁・発行日
vol.48, no.4, pp.463-472, 1994-08-25 (Released:2017-12-21)

This study was undertaken to assess the effect of different concentrations of nitrous oxide combined with a low dosage of midazolam on pain sensation in the buccal region of the human face. Twenty healthy subjects (male : 16, female : 4), male and female varying in age from 23 to 28 years (mean ; 24.9 years) and from 23 to 30 years (mean ; 25.8 years), and weighing from 52 to 85 kg (mean ; 66.1 kg) and from 46 to 49 kg (mean ; 47.1 kg) respectively, were involved in this study. All subjects were administered midazolam (0.025 mg/kg) intravenously, and divided into three groups ; the first inhaled 25% N_2O and 75% oxygen (25% N_2O group), the second inhaled 40% N_2O and 60% oxygen (40% N_2O group), and the third inhaled 60% N_2O and 40% oxygen (60% N_2O group). All subjects were reclined on dental chair comfortably in the supine position 10 minutes prior to start of the experiment. Three control tests were carried out with inhalation of room air at 10 minute intervals. One of the three concentrations of nitrous oxide (25% N_2O, 40% N_2O and 60% N_2O) was inhaled within 5 minutes by face mask after injection of midazolam into the forearm without the subject's knowledge for 30 minutes, and the mask was removed after oxygen inhalation for 5 minutes in succession after turning off the nitrous oxide gas. Three tests each for thresholds of tactile sensation using nylon^[○!R] thread (point load 0.004 g, 0.01 g, 0.2 g), and of pain sensation using an esthesiometer (point load 1-10 g) on the buccal region of the face were made at 10 minutes' intervals during N_2O inhalation and withdrawal periods. The results obtained are as follows. 1) The threshold of tactile sensation in the buccal region increased 17% and 19% over the control in the 40% N_2O group and the 60% N_2O group, respectively, but there were no significant differences between the groups. 2) The threshold of pain sensation in the buccal region showed significant increases from the control value in the 40% N_2O group during N_2O inhalation period, and the 25% N_2O group and 60% N_2O group showed significant increases from the control value at the 10 minutes point and 30 minutes point in the inhalation period, respctively. Especially in 40% N_2O group, significant increases were seen much more than in the 25% N_2O group at the 30 minutes point in the inhalation period. 3) In the condition of consciousness of 25% N_2O group and 40% N_2O group, there were significant differences during the N_2O inhalation term, and significant decreases appeared in blood pressure and heart rate during the N_2O inhalation term. These results indicate that the analgesic effect of 40% nitrous oxide combined with midazolam and the sedative effect of 25% nitrous oxide combined with midazolam are better than those of the other concentrations of nitrous oxide. It is the best way of the dental treatment to use infiltration under the 25% nitrous oxide with midazolam (0.025 mg/kg) for patient pain and fear.
著者
花田 彰 蓑毛 研 中村 章 西田 泰章 天野 裕治 小林 和正 中須 英輔 渡辺 馨 榎並 和雅
出版者
一般社団法人 映像情報メディア学会
雑誌
映像情報メディア学会技術報告 (ISSN:13426893)
巻号頁・発行日
vol.26, pp.13-16, 2002
参考文献数
3
被引用文献数
5

NHKでは地上デジタル放送用の番組送出設備開発の一環として、TS伝送シームレス切り替え装置(以下TSスイッチャと呼ぶ)の開発を進めている。地上デジタル放送の番組配信回線は、放送波TS(MPEG2トランスポートストリーム)信号で伝送することにより放送回線経費の大幅な低減、マスターシステムのコンパクト化が期待される。TSスイッチャは、この放送波TSに対してローカル番組のシームレスな切り替え送出、映像スーパー、音声ミックス、字幕信号伝送多重、局間制御信号(Net-Q)の伝送多重などを行うもので、地域放送局の番組送出マスターシステムのキーデバイスとなる。
著者
天野 裕治
出版者
九州歯科学会
雑誌
九州齒科學會雜誌 : Kyushu-Shika-Gakkai-zasshi (ISSN:03686833)
巻号頁・発行日
vol.46, no.1, pp.319-328, 1992-02-25
被引用文献数
1

Using the technique of in vivo microdialysis, extracellular concentrations of serotonin and 5-hydroxyindoleacetic acid (5-HIAA) were determined in the striatum, thalamus, dentate gyrus and prefrontal cortex while Sprague-Dawley rats underwent immobilization stress for twenty minutes. Microdialysis probes had semipermeable cellulose tubes (molecular weight cutoff 50, 000 ; O.D. 0.22 mm). Perfusion was started at 12 or 36 hours after implantation of the microdialysis probe under a freely-moving condition. Measurements of the extracellular concentration of serotonin and 5-HIAA were made at twenty minute intervals, which were started 120 minutes after the onset of the perfusion. Serotonin and 5-HIAA were quantified by a high-performance liquid chromatography coupled with an electrochemical detector. Extracellular serotonin levels increased following twenty minute immobilization stress in all four regions of the rat brain. The immobilization stress relatively increased the extracellular serotonin levels in the prefrontal cortex and dentate gyrus. These results suggest that twenty minute immobilization stress induces the activation of serotonin release in rat brain regions concerning the induction of anxiety.
著者
立石 晃 天野 裕治 相田 高幸 福田 仁一
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.48, no.8, pp.423-426, 2002-08-20 (Released:2011-04-22)
参考文献数
10

A case of non-clostridial gas gangrene with sepsis in the maxillofacial region and neck caused byodontogenic infection is reported.A 74-year-old woman consulted our department because of painful swellingof the head and neck region.She had been treated for depression for about 20 years.Her general conditionwas classified as I-2 coma according to the Japan coma scale.Blood examination revealedleukocytosis, hepatopathy, nephropathy, hypoalbuminemia, and hyperglycemia.A computed tomographicscan showed gas accumulation with abscess formation in the temporal, buccal, submandibular, and cervicalregions.Administration of antibiotics (PAPM/BP) and gamma-globulin was followed by emergencysurgical drainage under general anesthesia. Microbiological examinations revealed Streptococcus pneumoniae in the abscess and Peptococcus asaccharolyticus in venous blood on the 1st disease day. Aftertreatment, the swelling disappeared and the results of blood tests became normal.However, a secondmicrobiological examination of venous blood also revealed Peptococcus asaccharolyticus on the 9 th diseaseday. Antibiotics (CLDM) were given from the 17th to 20th disease days.Hyperglycemia was controlledby insulin.She was discharged on the 53rd disease day.Rapid diagnosis by computed tomography, rapid surgical drainage, appropriate chemotherapy, and examinationsof blood cultures and for DIC are required to save patients'lives.