73 0 0 0 OA トマトを用いた新型インフルエンザに対する食べるワクチンの生産
Human Hepatitis E Virus (HEV)のカプシドタンパク質が自己会合したVirus-like particle (VLP)は、消化耐性と腸管免疫誘導活性を持つ、食べるワクチンとして注目されている。インフルエンザの共通抗原であるM2エピトープを融合したHEVのカプシドを、果実特異的なE8プロモーターの制御下で発現する遺伝子組換え栽培トマト(Solanum lycopersicum cv. マイクロトム x 愛知ファースト)を作出した。遺伝子組換え植物用の特定網室で栽培することにより、各種の動物実験に資するに十分量の果実を収穫した。
2 0 0 0 OA 筑波大学遺伝子実験センター長 鎌田博先生のご逝去を悼む(談話室)
- 著者
- 小野 道之
- 出版者
- 一般社団法人 植物化学調節学会
- 雑誌
- 植物の生長調節 (ISSN:13465406)
- 巻号頁・発行日
- vol.49, no.1, pp.85-87, 2014-05-30 (Released:2017-09-29)
- 著者
- 笹川 由紀 小野 道之
- 出版者
- 一般社団法人 日本科学教育学会
- 雑誌
- 科学教育研究 (ISSN:03864553)
- 巻号頁・発行日
- vol.32, no.3, pp.216-229, 2008-09-10 (Released:2017-06-30)
- 参考文献数
- 30
- 被引用文献数
- 5
In 2002, the guidelines concerning recombinant DNA experiments was renewed and now allows this experiment within a safety range at schools. It is said that the hands-on lab activity using the recombinant DNA experiment in high schools is very effective for understanding the basics of molecular biology, while making students interested in biotechnology and gene literacy education. Although it would be better for all students to experience, it, only a small number of student have a chance. We administered a questionnaire survey to teachers of biology and studied some cases carried out to popularize the recombinant DNA experiment. From these results, we investigated what is needed to make this experiment more popular in gene literacy education. The results of questionnaire survey showed that effective lessons mutually motivate teachers and students. Educational material kits make it easy for teachers to try and are useful for them. We know that is some good cooperation between school, university and administration, and therefore teacher motivation is very important. We conclude with 10 needs to popularize the recombinant DNA experiment; they are related in complex ways. It is important to carry out action continuously and see these things in the long-term.