5 1 0 0 OA Warburgの「癌細胞の起原」に就いて
2 0 0 0 OA 老年者の骨髄造血機能の特長について
- 著者
- 平木 潔
- 出版者
- 一般社団法人 日本老年医学会
- 雑誌
- 日本老年医学会雑誌 (ISSN:03009173)
- 巻号頁・発行日
- vol.8, no.2, pp.47-52, 1971-03-31 (Released:2009-11-24)
- 参考文献数
- 6
- 被引用文献数
- 1
1 0 0 0 OA 腫瘍ウイルスの形態と分類
- 著者
- 平木 潔 太田 善介 入野 昭三 三好 勇夫 瀬崎 達雄 原田 英雄 鈴木 信也 大里 尚司 永森 俤一郎 守屋 純一郎 六車 昌士 高杉 潔 駄場崎 浩 池田 一彦
- 出版者
- Okayama Medical Association
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.77, no.5-6, pp.795-835, 1965-06-30 (Released:2009-03-30)
- 参考文献数
- 229
Morphologic characteristics of most of known oncogenic viruses, some of which were investigated by us, were described in relation to their oncogenicity and their localizations in tumor tissues.Oncogenic viruses were classified into six groups: type A, B, C, D, E and F. Viruses pertaining to type A were presumably not mature virus particles. Some of them could, however, be immature form or incomplete form of oncogenic virus particles. Viruses belonging to type B, C, D, E, and F were represented by mammary tumor virus of mice, leukemia viruses of mice and chickens, polyoma virus, Shope fibroma virus and Lucké renal adenocarcinoma virus, respectively. They were different in size and shape, and in the mode of development.It was presumed that type B and C viruses were members of the Myxovisus group and type D viruses belonged to Adenovirus and the Papova virus group. It was also believed that type E and F viruses had in general the feature of the Pox virus group and Herpes virus group, respectively.
1 0 0 0 OA DEVELOPMENT OF SUBCUTANEOUS SARCOMAS IN SWISS MICE GIVEN REPEATED INJECTIONS OF BFNZENE IN OLIVE OIL
- 著者
- 平木 潔 入野 昭三 三好 勇夫
- 出版者
- The Japanese Cancer Association
- 雑誌
- GANN Japanese Journal of Cancer Research (ISSN:0016450X)
- 巻号頁・発行日
- vol.54, no.4, pp.427-432, 1963-12-31 (Released:2008-10-23)
- 参考文献数
- 13
Five of eight inbred Swiss mice given repeated injections of a small amount of benzene in olive oil developed subcutaneous sarcomas. One of the three tumors transplanted grew and is now maintained as transplants. Morphology of these tumors and histological changes in other organs are described. The present results indicate that benzene is capable of inducing solid malignant tumors in mice. No leukemia or lymphoma was observed among these experimental mice.
- 著者
- 平木 潔 太田 善介 三好 勇夫 原田 英雄 鈴木 信也 六車 昌士
- 出版者
- 日本ウイルス学会
- 雑誌
- ウイルス (ISSN:00426857)
- 巻号頁・発行日
- vol.16, no.1-2, pp.6-12, 1966-04-30 (Released:2010-03-16)
- 参考文献数
- 21
Spontaneous mammary carcinoma of AKR mice and Xray-induced mammary carcinoma of C58 mice, both known as low-cancer strains, were investigated by electron microscopy.In AKR mammary carcinoma, intracytoplasmic type A and extracellular type B particles were present. In C58 mammary carcinoma, extracellular type C particles were observed. In both tumors, mature virus particles, i.e. type B and type C particles, were formed by the process of budding of cytoplasmic membrane of carcinoma cells and present in the lumina of the milk ducts. Aberrant form of type C particles, which contained a filamentous structure instead of a nucleoid was also seen in C58 mammary carcinoma.In serial in vivo transplantation of those carcinoma cells to the same strain mice, these virus particles were always present and formed from carcinoma cells, although the number of virus particles reduced almost successively with transplantations in AKR mammary carcinoma.In tissue culture of C58 mammary carcinoma cells, type C particles similar to those in the original tumor were observed extracellularly. On the contraty to the presence of type B particles in the original AKR mammary tumor, however, two tissue culture strains derived from in vivo transplanted AKR carcinoma cells contained type C particles. These type C particles were conceivable to be the leukemia virus that naturally harbored in AKR mice and happened to have been tranferred to the tissue culture probably through its latent infection in carcinoma cells.
