著者

大重 彌吉

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.66, no.5, pp.933-949, 1954-05-31 (Released:2009-08-24)

参考文献数

17

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I have made a report about two villages which may be regarded as random samples of farm villages in mountainious districts, to offer such materials as will help to make accurate statistics in future.Schizophrenia shows a percentage of 0.49 to the population, the corrected frequency being 1.01% (dangerous age 16-40; referred number 2168.0), the percentage of manicdepressive psychosis in 0.04, the corrected frequency 0.12% (dangerous age 21-50; referred number 1710.0) and the percentage of essential epilepsy is 0.11. the corrected frequency 0.17% (dangerous age 21-30; referred number 2922.0).

著者

安部 益文

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.93, no.9-10, pp.941-949, 1981-10-30 (Released:2009-03-30)

参考文献数

14

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マイクロ波は周波数300MHz~30GHzの電波であるが,このマイクロ波の電界に誘電物質をおくと,電波エネルギーは物質に吸収され熱エネルギーに変る.この高周波誘電加熱に立脚して開発された電子レンジが日常の簡易滅菌に如何なる有効性を示すかを検討した.供試微生物はS. aureus, E. coli, Ps. aeruginosa, B. subtilisの芽胞, C. albicans, Echo virus及びHerpes simplexである.これらをガラス及びプラスティク哺乳瓶に定量的に附着させ電子レンジ(2450MHz 500W)で照射した.微生物の大低のものは5~6分,芽胞でも7分で完全死滅した.付着後乾燥状態にした場合はやや長時間を要したが,芽胞やウイルスでも12分では完全死滅した.以上のことから,マイクロ波による滅菌はその局部内部加熱作用が微生物の滅菌に有効に働き,包装状態のままで短時間で行える上に,プラスティク,ゴムなどの容器は損傷されず極めて有用性の高いことが判明した.

著者

前橋 明

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.102, no.11-12, pp.1229-1239, 1990 (Released:2009-03-30)

参考文献数

15

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In order to determine the effects of physical loading on the health status of children who attend swimming classes, subjective and objective changes caused by exercise were studied. In addition, this study also attempts to understand the place of outdoor exercise in daily life and to grasp fundamental problems of health care for children.In my investigation, 43 children exercised in a swimming pool for 75 minutes, and subjective symptoms of fatigue, flicker fusion values, and excretion of uninary protein before and after swimming were analyzed.The results revealed that so-called Group I and III subjective symptoms of fatigue were increased after swimming as compared with before suggesting that physical and nervous symptoms were induced by swimming. However, Group II symptoms, i.e. psychological complaints, were decreased, compared with before swimming.Second, flicker fusion values for the whole sample before and after physical loading were not changed by exercise, though swimming tended to decrease flicker fusion values in boys (p<0.05). On the other hand, the flicker fusion value tended to increase in girls (p<0.05).Third, the excretion of urine per hour was increased (p<0.05) after swimming in an exercise-dependent manner, though the specific gravity of urine significantly decreased (p<0.01).Finally, urinary pH tended to decrease in boys but did not change in girls after swimming, and the concentration of urinary protein was significantly lower after swimming (p<0.01).

著者

大月 三郎 秋山 一文 森本 清

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.103, no.3, pp.187-196, 1991-06-18 (Released:2009-08-24)

参考文献数

46

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Abuse of psychostimulants such as methamphetamine by humans leads to psychotic symptoms which are virtually indistinguishable from those of paranoid schizophrenia. A similar progressive augmentation was observed in locomotion and stereotyped behavior of animals receiving chronic administration of methamphetamine. Thus, such behavioral sensitization or reverse tolerance phenomenon has been well established as an animal model of susceptibility to exacerbation of methamphetamine-induced paranoid psychosis and schizophrenia. On the other hand, kindling refers to a phenomenon whereby a progressively increasing epileptiform discharge emerges after repeated electrical stimulation in a limbic area and finally culminates in a generalized seizure. Kindling has been best characterized as a model of human temporal lobe epilepsy. This review summarizes the studies on reverse tolerance and kindling phenomenon so far conducted in our department. Acute exacerbation following a re-challenge of methamphetamine in the methamphetamine-treated animals is associated with enhancement of dopamine release in the striatum. The pharmacological and electrophysioloical studies of kindling revealed cumulative evidence that excitatory amino acids play an important role in the induction mechanism of kindling, but that the seizure triggering mechanism may be related to collapse of inhibitory gamma-aminobutyric acid function. Further studies are necessary to understand these two important phenomena for psychiatry.

著者

吉井 清水

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.70, no.3, pp.879-903, 1958-03-31 (Released:2009-03-30)

参考文献数

17

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1. The author has made researches, in summer, autumn and winter, of the quantitative variation, following the time after death, of the non-protein nitrogen in bones and cartilages, and the anorganic phosphoric, sulphuric and nitric acid in brains, lungs, livers, kidneys and spleens of rabbits.2. Each quantities of the non-protein nitrogen in bones and cartilages increase following the time for a certain period after death. The quantities of the anorganic acids in these five organs increase similarly following the time after death, and then decrease after a certain period.3. The author has proved that the disintegration of dead bodies is more speedy 8-11 times in summer and 3-4 times in autumn than in winter.

著者

長島 洋

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.98, no.7-8, pp.669-685, 1986-08-30 (Released:2009-03-30)

参考文献数

28

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The purpose of the present study was to investigate experimentally the formation of ethanol in corpses and stored biological samples important in medicolegal examination, and to study the mechanism of ethanol formation.In the tissues and bodily fluids of corpses, ethanol, n-propanol, iso-propanol, acetaldehyde, acetone and others may be formed to various degrees according to the post-mortem conditions. The criteria of post-mortem ethanol formation are 20°C and 24 hours of post-mortem time, and a significant amount of ethanol can be formed at higher temperatures and longer times. The presence of n-propanol in samples may be useful for ascertaining post-mortem ethanol formation. The amount of ethanol formed post-mortemly may be presumed to be under 20 times of the amount of n-propanol simultaneously detected.Post-mortem ethanol formation is not increased by ante-mortem ethanol intake. Ethanol may be produced in biological samples including cadaveric blood. Fresh aseptic blood is not conducive to ethanol formation within five days.The formation of n-propanol due to yeast in the stomach of corpses is lower than that due to bacteria in other organs and bodily fluids. The addition of antibiotics, which suppress the bacterial growth in the samples, and the addition of chemical inhibitors of ADH and ALDH contained in bacteria comletely blocked ethanol formation.It may be considered that ADH and ALDH in the bacteria in corpses produce ethanol from carbohydrates such as glucose and pyruvic acid through the reverse pathway of ethanol metabolism in living subjects.

著者

水野 一郎

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.71, no.8-2, pp.5221-5229, 1959-08-15 (Released:2009-03-30)

参考文献数

16

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Several experiments on the adhesion of tenden were performed with adult rabbits, and following results were obtained.1). Adhesion of tendon seen after removal of the paratenon was most intensive in two to three weeks.2). The adhesion was less in the tendon preserved paratenon, which was thought to be a factor affecting the adhesion of tendon.3). Although the adhesion was slight in the crushed tendon, for the paratenon was preserved, the fixation of two to three weeks' duration was necessary for restoration of the tendon.4). On the prevention of adhesion the effect of wrapping tendon in living fascia or polyethylene membrane was studied comparatively. The result was better in polyethylene membrane, which prevented the adhesion perfectly.5). It was undesirable to wrap tendon in polyethylene membrane immediately after suture or transplantation, because of its complete interception of cell permeation disadvantageous to repair of the tendon.6). Repair of the tendon were thought to be incompatible with prevention of adhesion. It was, therefor, reasonable to intend prevention of readhesion after separation of adhesion, and best result was obtained with polyethylene membrane.

著者

康 逸雄

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.78, no.1, pp.159-170, 1966-01-30 (Released:2009-02-13)

参考文献数

24

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In this experiment, the author investigated the changes of blood and urine of the rescue team workers engaging in heavy tasks in high thermal conditions, in addition to the reaffirmation of the previous results. Further, he encountered several cases of heat stroke occasionally. The followings were the results obtained: 1. Change of pulse pressure which the results were obtained previously was affirmed statistically by increasing the number of the cases. 2. The cases of heat stroke suggested that the threshold limit of the increase of pulse pressure seemed to exist around the rate of 150%. 3. The threshold limit of body temperature (under tongue) was around 39°C. 4. By remarkable sweating after the task, blood was concentrated, resulting the increase of specific gravity of the total blood, proteine in plasma, hematocrit value and hemoglobin content. 5. The group of heat stroke showed higher pulse pressure, higher pulse rate, higher temperature under the tongue and has a tendency of a higher rate of blood concentration. 6. Life-saving mask type 4 produced heat when soda lime absorbed CO2 expired in the circulaing air. But the influence of the high temperature and high humidity of the environment was greater than the heated air-input of the mask. 7. The limitation of the continuity of the task in such a high thermal condition seemed to be around 30 minutes. The resting time was needed at least 90 minutes for adequate recovery.

著者

小松原 正吉

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.90, no.1-2, pp.101-119, 1978-02-28 (Released:2009-03-30)

参考文献数

37

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A pertinent procedure for preserving postoperative urinary and sexual functions was searched in the radical surgery for rectal cancer, from a neuroanatomical point of view, and the clinical status about disturbances of these functions was analized in relation with a mode of preservation of the lower hypogastric and/or the pelvic nerve among the patinet undergone the surgery applied this procedure. The result of the operation was also evaluated as for the influence of this procedure on the curability of the cancer.Results obtained were as follows:1. In the anatomical study with 17 necropsy cases, it was found that the most preferable mean for identifying the lower hypogastric nerve, pelvic plexus and pelvic nerve was to begin with isolating the upper hypogastric nerve dividing the posterior peritoneum along the lower abdominal aorta, and to follow the bilateral lower hypogastric nerves on the inner surface of the pelvic cavity down to the pelvic plexus, from which the pelvic nerves were able to explore by the retrograde approach to the sacral foramina. Since this procedure was able to be progressed in accordance with that of the radical operation by Miles, technical troubles were of eliminable.2. Urinary functions were examined on 47 cases out of 60 patients received the surgery with the nerve-saving procedure above.a) The period before the spontaneous urination occurred after the surgery was prolonged significantly by the bilateral injury to the pelvic nerve and this was not observed in the patient whose pelvic nerve was unilaterally injured, as well as in the patient whose lower hypogastric nerve was uni- or bilaterally injured.b) The result of cystometry and catheterization study showed that cystic hypotonia and urinary retention prolonged as long as 40 days or more, and 23 days in average in the patient with injury to the bilateral pelvic nerves, as compared to 8 days in average in the patient with bilateral denervation of the lower hypogastric nerve and also in the patient with unilateral injury to the pelvic nerve. Duration of sensation as to urinary retention was quite accorded with these results.3. Sexual function was surveyed making inquiries by the letter to 48 subjects and was summarized on 43 including 19 female with satisfactorily recorded answers.a) Ability of the erection was preserved in about 60 to 70% of the patient regardless of presence or absence of the denervation of the lower hypogastric nerve. However, it was impaired in all patients with bilateral injury to the pelvic nerve, although even the unilateral preservation saved the ability in all.b) Ability of the ejaculation was satisfactorily kept only in the subjects whose lower hypogastric nerve was bilaterally saved. Among those who had injury to bilateral pelvic nerve, only the patient whose lower hypogastric nerve was bilaterally saved preserved the ability, suggesting a close participation of the hypogastric nerve to the ejaculation.4. The decrease in the curability of the cancer under this procedure was not observed, compared with that in patients undergone the surgery performed without the positive intention to save the nerve but with the aim to eradicate the cancer.

著者

松海 信彦

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.101, no.11-12, pp.1049-1061, 1989 (Released:2009-03-30)

参考文献数

44

被引用文献数

1

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The thermal damage threshold of brain tissue was estimated from the immediate and delayed histological changes caused by 2450 MHz microwave antenna and an antenna cooling system of a device used for interstitial hyperthermia treatment. An antenna within a cooling system was inserted through the small cranietomy under general anesthesia. The temperature at a reference point, 4 mm radially away from the surface of the cooling system, was maintained at 42 °C, 43 °C, 44 °C, 45 °C or 46 °C for 60 minutes. In a non-survival experiment, 18 animals were used and sacrificed immediately after the treatment. In a survival experiment, 9 animals were used and sacrificed seven days after the treatment. The histological changes were evaluated by microscopic examination with hematoxylin and eosin, Klüver-Barrera, or Bodian stainings. In the non-survival experiment, areas heated below 44 °C showed no obvious irreversible change. In the survival experiment, areas heated at 44 °C or above showed coagulative necrosis. Those histological findings indicate that the thermal damage occurs in normal brain tissue after heating at 44 °C or above for 60 minutes, and suggest that the safety limit for brain hyperthermia is 43 °C for 60 minutes.

著者

石津 日出雄 宮石 智 山本 雄二 高田 真吾

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.105, no.9-10, pp.839-845, 1993 (Released:2009-03-30)

参考文献数

5

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A 63-year-old male died in the hospital from erroneous drip infusion of thrombin, a local hemostatic, after polypectomy for intestinal polyposis. At autopsy, thromboses were observed in the cutaneous veins of the right arm, the right axillary vein and the right subclavian vein, and soft fibrin clots in the superior vena cava, the right atrium, the right ventricle and the pulmonary arteries. Thrombi were also found in the rami of the arteries in both lungs under the microscope. Leucocyte infiltration was recognized in the thrombus, but no organization. This finding shows that the thrombi were fresh. The remainder (150ml) of the drip solution was analyzed for thrombin activity and 8 to 16 units of thrombin activity per ml were demonstrated. From these results, the cause of death was considered pulmonary thrombosis due to intravenous administration of thrombin.

著者

国府島 泉 山本 洋 山本 マリリア明美 中村 知明 長町 栄子 寺坂 昌子 金政 泰弘

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.96, no.3-4, pp.385-389, 1984-04-30 (Released:2009-03-30)

参考文献数

11

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電子レンジによるおしぼり付着菌の殺菌効果について検討した.菌付着おしぼりを1本ずつ照射する実験ではE. coli, S. aureus, P. aeruginosaの細菌類は2分間程度のマイクロ波照射で殺菌された.真菌類のC. albicansも3分で殺菌された.しかしB. subtilisの芽胞は5分間のマイクロ波照射でも10%の生残が認められた.実際面を考慮しておしぼり10本程度を同時に行なう場合は,効率的にやや長時間を要するが,芽胞以外のものを対照にする限り5分照射で充分である.電子レンジによるおしぼりの殺菌は手軽に短時間にしかも効果的になされることが判明し,自家処理おしぼりの殺菌にはもちろんのこと業者処理おしぼりの追加殺菌にも有用であると考えられる.

著者

牧山 宏志

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.71, no.6-1, pp.3077-3084, 1959-05-01 (Released:2009-03-30)

参考文献数

18

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On the basis of the findings on the relationship between tubal muscles and the Eustachian tube as described in the previous report, the actions of various tubal muscles on the Eustachian tube are discussed, and the observations carried out by the methods described below on the movements in vivo of the naso-haryngeal orifice at the time of phonation and of swallowing reveaied the following results.1. Observations were carried out with the use of a nasopharyngoscope.2. Observations were done on the patients who underwent the radical operation for the cancer of maxillar sinus. As the inferior nasal concha was already removed at the time of the operation, it was possible to insert a small nasal mirror into the posterior nasal cavity of the operated side to catch the whole view around the tubal orifice of healty side.3. For the children over 5-6 years old with cleft palate, observations were carried out directly on the pharyngeal orifice through the mouth cavity (motion pictures were taken in this instance).At a result it has been found that the nasopharyngeal orifice of the tube is widened because the posterior lip and the mucous membrane of the base of the Eustachian tube move slightly outward at the time of swallowing. In anatomically summarizing these observations the author arrived at the following conclusions.At the time of swallowing the tensor muscle of the palate dilates the Eustachian tube at the points near the middle part and the anterior part of the tube. The levator palatini muscle assists the opening action of the tensor muscle by fixing or by drawing the base of the tube slightly toward the inferior-interior side. The salpingopharyngeus muscle or the salpingopharyngeal fold, being drawn inward by the cephalopharyngeal muscle and pahryngopalatine muscle and widening the nasopharygeal orified, assists the dilatating action of the tensor muscles.When the muscles are relaxed, the Eustachian tube is closed probably by the elasticity of the lateral cartilaginous lamina and by the pressure of the tissues surrounding the tube.

著者

新井 達潤

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.89, no.1-2, pp.21-36, 1977-02-28 (Released:2009-03-30)

参考文献数

59

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Ventricular fibrillation was induced in fifteen monkeys by electric stimulation using a bipolar intracardiac pacemaker electrode which was inserted through a femoral vein. The monkeys were defibrillated and resuscitated after several minutes. Cerebral blood flow (CBF), intracranial pressure (ICP) and EEG were monitored continuously. CBF autoregulation was checked regularly before and after ventricular fibrillation to study the relation between it and other parameters such as CBF, ICP, EEG.Fifteen monkeys were divided into two groups, a burr-hole group and a no burr-hole group. ICP was measured in the burr-hole group (10 monkeys). The purpose of having two groups was to ascertain the effect of a burr-hole (artificial injury in the skull and dura) on the parameters CBF, EEG and autoregulation. CBF was measured with electromagnetic flowmeter at internal carotid artery.The conclusion of the experiment was as follows;(1) Autoregulation was lost in all monkeys after resuscitation. In the monkeys which had had autoregulation before cardiac arrest, the autoregulation recovered in three (no burr-hole group) to five (burr-hole group) hours after resuscitation, if resuscitation took place within five minutes. In the monkeys whose autoregulation had already been lost before cardiac arrest, it did not return despite successful cardiac resuscitation.(2) Immediately after resuscitation, BP, ICP and CBF increased for 20-60 minutes. In the monkeys who had no recovery of autoregulation after resuscitation, the rate of increase of ICP was much larger than those whose autoregulation recovered, and at the peak of ICP, the CBF decreased. Impairment of autoregulation itself, indicates that the ballance of circulatory dynamics of the brain is easily impaired by noxious stimulation such as hypoxia.(3) In the monkeys with recovery of autoregulation, general status was good after resuscitation but in the monkeys without recoverey, symptomes of increased ICP were seen and the prognosis was poor.(4) Six minutes of cardiac arrest would appear to be the upper limit for monkeys to survive after resuscitation.(5) Before ventricular fibrillation, corresponding changes in the CBF and the frequency of the EEG wave recorded, but after resuscitation the frequency of the EEG wave decreased despite an increase in CBF. This is probably the same mechanism as occures in the “luxury perfusion syndrome”.There was no relation between EEG and autoregulation, but when EEG showed dominant slow or flat waves, there was no autoregulation.

著者

杉山 明

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.99, no.3-4, pp.251-260, 1987-04-30 (Released:2009-03-30)

参考文献数

20

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The kinetics of serum ferritin were studied in 42 male patients with alcoholic liver diseases (17 with alcoholic fibrosis, 10 with alcoholic hepatitis and 15 with alcoholic cirrhosis). In addition, the chromatic reaction of biopsied liver tissue to ferritin staining (PAP method) was examined and compared with serum ferritin levels and the iron-staining data. Serum ferritin levels in patients with alcoholic liver diseases, determined immediately after abstinence, were significantly higher than those in normal controls, although no significant difference was noted in serum ferritin among the different disease types. The serum ferritin levels decreased exponentialy after abstinence regardless of the disease type. There were positive correlations between serum ferritin and the intensity of hepatic hemosiderin and between the intensity of hepatic hemosiderin and hepatic ferritin. These correlations indicate that the ferritin level changes according to the amount of hepatic iron stores. These results indicate that hyperferritinemia of patients with alcoholic liver diseases reflects an increase in hepatic iron stores and that the escape of hepatic ferritin due to hepatocellular damage and the reduced clearance of serum ferritin are also related to hyperferritinemia.

著者

高原 光弘

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.91, no.9-10, pp.1235-1248, 1979-10-30 (Released:2009-03-30)

参考文献数

37

被引用文献数

1 1

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Persistent juvenile T wave patterns found in mass examination and in clinical cases were studied for the purpose of clarifying their significance. Persistent juvenile T wave patterns were classified into three types. Type I had negative T waves in lead V1 only, Type II in lead V1 and V2 and Type III in V1 to lead V3 or V4. During mass examinations, persistent juvenile T wave patterns were found in 243 cases (43.5%) of 558 male subjects. Of these, 15 (6.2%) were Type II, III. On the other hand they occurred in 547 (66.5%) of 823 female subjects. Of these, 86 (15.7%) were Type II, III. The incidence of each Type of persistent juvenile T wave pattern did not vary significantly with age, but Type II, III were relatively more frequent between 35 and 49 years of age. Persistnet juvenile T wave patterns were often positive in many cases in electrocardiograms (ECG) thaken from the same subjects 8 years after the first mass examination. Standard ECG's and Frank's system vectorcardiogram (VCG)'s were analysed in 116 clinical cases showing persistent juvenile T wave patterns. Transitional zone and electrical axis deviation in ECGs were almost normal in the persistent juvenile T wave pattern. The shape of the transverse T loop was mostly normal whereas the transverse QRS loop normally varied in shape. Clockwise rotation of the transverse T loop was observed in 15 of 116 clinical cases. The maximum magnitude of the T loop in VCG was significantly smaller in Type III than in Type I, II. Changes in the persistent juvenile T wave pattern on ECG and VCG were studied in 25 cases after administration of Propranolol. The negative T wave in ECG tended to become positive and the maximal T vector tended to become larger shifting towards anterior in VCG after administration of Propranolol. The persistent juvenile T wave pattern was observed more frequently in middle aged women and usually became normal after administration of Propranolol. These results suggest that increased sympathetic tone is one of the pathological mechanisms involoved in the persistent juvenile T wave pattern.

著者

山元 敦也

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.105, no.5-6, pp.629-639, 1993 (Released:2009-03-30)

参考文献数

13

被引用文献数

1 1

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It was previously reported that the elevation of inorganic fluorine level in plasma after inkalation of methoxyflurane causes acute renal failure. This study investigated whether the peak concentration or the duration of the inorganic fluorine is responsible for the renal failure. Continuous infusion (5 millimols/liter and 10 millimols/liter) or a single intravenous bolus injection (720 millimols/liter) of sodium fluoride solution was administered to rabbits. The plasma concentration and the duration of the plasma fluorine was measured.There werer no signs of pathological or biochemical changes that suggested renal failure when the peak plasma concentration was less than 50 millimols/liter for over 4 hours (5 millimols/liter, 24 hours), or whether peak concentration of plasma inorganic fliorine was over 50 millimols/liter for less than 4 hours (720 millimols/liter, intravenous bolus). However when 10 millimols/liter of sodium fluoride solution was administered at a speed of 10 milliliters/hour for 24 hours, the rabbits showed a peak plasma inorganic fluorine concentration over 50 micromols/liter for more than 4 hours and signs of renal failure developed ata plasma concentration of 65.8 micromols/liter 24 hours after the beginning of infusion. renal failure was mainly inthe form of edema of the tubular cells in both the cortex and medulla and abnormal biochemical changes (blood urea nitrogen 55.8±12.5 milligrams/deciliter, plasma creatinine 1.2±0.1 milligrams/deciliter).Inorganic fluorine can cause renal changes when its paek plasma concentration reaches more than 50 micromols/liter and lasts for more than 4 hours.

著者

片山 昭

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.91, no.7-8, pp.847-860, 1979-08-30 (Released:2009-03-30)

参考文献数

12

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In order to study the fundamental touch in piano playing, the physiological mechanics of the player and the kinetic mechanics of the swing-stroke system in the piano need to be studied.Equipment for analyzing and measuring the intensity of the swing-strokes has been developed to study the fundamental touch in piano playing. This equipment measures the velocity of the hammer and indicates the relationship of the intensity and the velocity of the swing-strokes.The tone-volume depends on the amount of kinetic energy which the player spends in striking the key. The kinetic energy is in direct proportion to the mass set in motion and is the square of the velocity.The mass set is always constant and the energy depends only upon the velocity of the hammer. Thus it is possible to analyze the tone-volume by measuring the velocity of the hammer.Two methods of swing-strokes were set up to analyze the movement of the swing-stroke. Two experiments were performed: (a) static swing-stroke in which the height of the swingstroke was fixed and the weight was changed and (b) dynamic swing-stroke in which the weight of the swing-stroke was fixed and the height was changed.Experiments with the swing-stroke were made by a skilled pianist. The control system of the intensity of the swing-strokes is discussed.

著者

平木 潔 太田 善介 入野 昭三 三好 勇夫 瀬崎 達雄 原田 英雄 鈴木 信也 大里 尚司 永森 俤一郎 守屋 純一郎 六車 昌士 高杉 潔 駄場崎 浩 池田 一彦

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.77, no.5-6, pp.795-835, 1965-06-30 (Released:2009-03-30)

参考文献数

229

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Morphologic characteristics of most of known oncogenic viruses, some of which were investigated by us, were described in relation to their oncogenicity and their localizations in tumor tissues.Oncogenic viruses were classified into six groups: type A, B, C, D, E and F. Viruses pertaining to type A were presumably not mature virus particles. Some of them could, however, be immature form or incomplete form of oncogenic virus particles. Viruses belonging to type B, C, D, E, and F were represented by mammary tumor virus of mice, leukemia viruses of mice and chickens, polyoma virus, Shope fibroma virus and Lucké renal adenocarcinoma virus, respectively. They were different in size and shape, and in the mode of development.It was presumed that type B and C viruses were members of the Myxovisus group and type D viruses belonged to Adenovirus and the Papova virus group. It was also believed that type E and F viruses had in general the feature of the Pox virus group and Herpes virus group, respectively.

著者

高橋 義雄 難波 祐三郎 岸本 晃司 光嶋 勲

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.113, no.3, pp.279-284, 2001-12-31 (Released:2009-03-30)

参考文献数

9

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GENDER IDENTITY DISORDER (GID) is a unique human condition that is classified behaviorally and treated medically with hormones and surgery in the severe form. This condition has been and still somewhat remains controversial by religious beliefs, social institutions and health care delivery systems. We described the surgical management of transsexuals, so called SEX REASSGINMENT SURGERY (SRS) and showed the team for gender treatment, GENDER CLINIC. A gender treatment team composing staff members from the Psychiatric, Plastic Surgery, Urology, Obstetric/Gynecological Surgery, and the Social Service, was established at the Hospital of Okayama University Medical schools in 1999. Female-to-Male procedures include mastectomy, phalloplasty, Phalloplasty are completion and an appurtenance, something pleasing to others. Male-to-Female program includes the genital surgery. The genital change surgery consists of the penile inversion, orchiectomy, vaginoplasty. Other procedures include reduction thyroid chondroplasty, hair transplant, voice change, laryngeal surgery, epilation with the laser.SRS is the only effective treatment available today in the management of GID. The aesthetic and functional results achievable from various procedures are generally satisfactory and are acceptable to the patients. On the other hand, we should remember that the numerous steps of information for SRS will be required.