著者
朝比奈 菊雄 峯尾 章伍 吉田 光雄
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.75, no.9, pp.1115-1119, 1955-09-25 (Released:2010-02-19)
参考文献数
1

Using the usual tabletting machine used in the factory and without changing the amount of granules supplied, two kinds of granules were submitted to tabletting at a constant tabletting speed, the same mortar volume, and in three positions of the upper pounder (giving three different thicknesses of tablet), and correlation between the forming pressure measured and various characters of the products was examined. From such results, following points were clarified:1) Naturally, there was no relation between pressure and weight of the tablet but differentiation by the position of the upper pounder (thickness of tablets) showed that there existed a positive correlation within each stratum. Appearance of such correlation in the case of one of the granules was found to be the interference of the change in the amount of granules supplied into the factor of the position of the upper pounder.2) There is a negative correlation between pressure and thickness but differentiation by the thickness indicated the presence of a positive correlation. This indicates that there is a positive correlation between weight and thickness.3) There is positive correlation between pressure and the quotient of weight by thickness.4) There is a positive correlation between pressure and compressive strength.5) Within the conditions used in the present experiments, no difference was found in the results from two kinds of granules.
著者
松丸 秀夫 朝比奈 菊雄 加藤 仁
出版者
公益社団法人 日本薬学会
雑誌
ファルマシア (ISSN:00148601)
巻号頁・発行日
vol.14, no.2, pp.117-122, 1978-02-01 (Released:2018-08-26)

木枯しが吹き出すと落ちつかなくなり, そして雪が降る頃には時々姿を消し, 黒くなった顔で現われる人種, スキーの楽しさにとりつかれた人達-."スキー狂師"であることを自他共に認めておられる薬学人もあちらこちらに数多いようである.そこで, このような方々の間での隠された逸話や思い出話の一端なりとも御被露していただこうと先生方にお集りいただいたが, 出席を予定されていた津田先生には御都合がつかず, 紙上参加の形で思い出話を寄せていただいた.
著者
朝比奈 菊雄 吉中 邦子
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.73, no.5, pp.501-505, 1953-05-25 (Released:2010-02-19)

Attempt was made to obtain homogeneous vitamin B1 tablets by the improvement of manufacturing processes from finding the cause of variations in content of vitamin B1. As a result it was experimentally confirmed that the following equation is establishedσr2=σw2+σc2+σm2+2ρ⋅σw⋅σcwhen σr, σω, σc and σw respectively stand for the observed value, weight, content per unit weight, and standard deviation of determined value, and ρ, the coefficient of interdependence. From these findings, improvements were made on the mixing and granulation processes. Examinations were also made on the thiochrome process for determination of vitamin B1, conditions for direct absorption determination, and interdependence.
著者
松丸 秀夫 朝比奈 菊雄 加藤 仁
出版者
公益社団法人日本薬学会
雑誌
ファルマシア (ISSN:00148601)
巻号頁・発行日
vol.14, no.2, pp.117-122, 1978-02-01

木枯しが吹き出すと落ちつかなくなり, そして雪が降る頃には時々姿を消し, 黒くなった顔で現われる人種, スキーの楽しさにとりつかれた人達-."スキー狂師"であることを自他共に認めておられる薬学人もあちらこちらに数多いようである.そこで, このような方々の間での隠された逸話や思い出話の一端なりとも御被露していただこうと先生方にお集りいただいたが, 出席を予定されていた津田先生には御都合がつかず, 紙上参加の形で思い出話を寄せていただいた.