著者

Kenji Iwaku Jaeduk Yoshimura Noh Eiji Sasaki Nami Suzuki Tosiaki Kameda Sakiko Kobayashi Ai Yoshihara Hidemi Ohye Natsuko Watanabe Miho Suzuki Masako Matsumoto Yo Kunii Koji Mukasa Kiminori Sugino Koichi Ito

出版者

(社)日本内分泌学会

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.61, no.9, pp.875-881, 2014 (Released:2014-09-29)

参考文献数

20

被引用文献数

2 11

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Following the accident at the Fukushima Daiichi Nuclear Power Station which occurred on March 11, 2011 due to the Eastern Japan Great Earthquake (the Accident), there have been concerns over elevation of the risk of thyroid cancer among children due to internal exposure to radioactive iodine. In Fukushima Prefecture, screening of children with thyroid ultrasonography has been carried out, yielding numerous findings, suggesting a possible influence from the Accident. We report thyroid ultrasonographic findings, used by similar device at Fukushima Prefecture’s study, at Ito-hospital. Of the 2721 children aged 15 or less who visited our hospital between January 2005 and March 2013, 1214 children (330 boys and 884 girls; median age, 12; range of age, 4-15) were covered by evaluation of thyroid ultrasonographic findings, excluding children known in advance to have thyroid disease on the basis of disease history, palpation and blood tests. Among these 1214 children, 709 children (58.4%) were found cysts (≤5 mm in 665 cases) by ultrasonography, 43 children (3.5%) were found nodules (≤5 mm in 18 cases) and 9 children (5.2%) were found an intrathyroid ectopic thymus. Analysis of the data before and after the Accident using the same device, involving age adjustment on the basis of the standard population in 2010, showed no difference in the incidence rate of cysts or nodules. In children examined, the incidence rate of cyst formation (particularly ≤5 mm) was higher, and there was no difference in the incidence rate of cysts or nodules between the pre- and post-accident period.

著者

Koichi Ito Takafumi Aoki

出版者

The Institute of Image Information and Television Engineers

雑誌

ITE Transactions on Media Technology and Applications (ISSN:21867364)

巻号頁・発行日

vol.6, no.1, pp.64-80, 2018 (Released:2018-01-01)

参考文献数

82

被引用文献数

9

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This paper presents recent advances in biometric recognition, where we focus on face, fingerprint and iris recognition, which are major research topics on biometric recognition. We summarize the research trend of face, fingerprint and iris recognition over the past decade. This paper also presents our activities of biometric recognition. Our approach employs the phase information obtained by Discrete Fourier Transform (DFT) of images. The phase information preserves the inherent features of the image, and its correlation function, called phase correlation or Phase-Only Correlation (POC), gives us both the good similarity measure for biometric recognition and the translational displacement for image registration. Our approach of using phase information has been successfully applied to fingerprint, face, iris, palmprint, finger knuckle and dental recognition. Among them, we present some interesting results of palmprint recognition, finger knuckle recognition and dental recognition.

著者

伊藤 孝一 Koichi Ito

出版者

淑徳大学人文学部紀要委員会

雑誌

研究論集 (ISSN:21895791)

巻号頁・発行日

no.3, pp.85-96, 2018

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日本のテレビ放送が始まって64年が経ち、テレビはメディア・コミュニケーションの中心的な役割を担い、人々に大きな影響を与えてきた。テレビ番組のなかで、報道やスポーツとならぶ大きな存在であり、大衆文化を先導してきたのがドラマである。今日、インターネットやスマートフォンの普及によるデジタルネットワーク社会の進展やオーディエンスの視聴環境がドラマの企画や表現の創造性="クリエイティビティ"に大きな影響を及ぼしていると思われる。ドラマは「時代を映す鏡」といわれて久しいが、時代とドラマの創造性="クリエイティビティ"との関係に視点をおき、現在のテレビドラマにおけるクリエイティビティを考察する。

著者

Luis Rafael MARVAL-PÉREZ Koichi ITO Takafumi AOKI

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences (ISSN:09168508)

巻号頁・発行日

vol.E102-A, no.10, pp.1351-1363, 2019-10-01

被引用文献数

1

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Access control and surveillance applications like walking-through security gates and immigration control points have a great demand for convenient and accurate biometric recognition in unconstrained scenarios with low user cooperation. The periocular region, which is a relatively new biometric trait, has been attracting much attention for recognition of an individual in such scenarios. This paper proposes a periocular recognition method that combines Phase-Based Correspondence Matching (PB-CM) with a texture enhancement technique. PB-CM has demonstrated high recognition performance in other biometric traits, e.g., face, palmprint and finger-knuckle-print. However, a major limitation for periocular region is that the performance of PB-CM degrades when the periocular skin has poor texture. We address this problem by applying texture enhancement and found out that variance normalization of texture significantly improves the performance of periocular recognition using PB-CM. Experimental evaluation using three public databases demonstrates the advantage of the proposed method compared with conventional methods.

著者

Chisato Tomoda Yuna Ogimi Fumi Saito Chie Masaki Junko Akaishi Kenichi Matsuzu Akifumi Suzuki Takashi Uruno Keiko Ohkuwa Hiroshi Shibuya Wataru Kitagawa Mitsuji Nagahama Kiminori Sugino Koichi Ito

出版者

(社)日本内分泌学会

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ15-0631, (Released:2015-12-10)

被引用文献数

1 6

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Metastatic differentiated thyroid carcinoma (DTC) is an uncommon cause of malignant pleural effusion (MPE) and the characteristics and clinical course have been rarely described. Herein, we report a retrospective review of the clinical course of 18 patients (15 women and 3 men) with MPE from DTC who underwent treatment at our institution between January 2005 and December 2014. MPE from DTC was diagnosed based on cytology and/or level of thyroglobulin in the pleural fluid. Pathologically, papillary carcinoma was found in 16 patients and follicular carcinoma in 2 patients. Median ages at initial diagnosis of DTC and MPE were 64 years (range, 22-79) and 74 years (range, 39-86), respectively. All patients showed radiologically apparent lung metastases, with MPE developing after 0-212 months (median, 25). In 16 patients (88.9%), other coexistent distant metastases at the time of MPE diagnosis were found in the bone (n = 10), brain (n = 5), and skin (n = 2). All patients were treated conservatively with palliative thoracentesis or chest tube drainage with or without pleurodesis. Recurrent MPE after treatment was seen in 9 patients; discharge to home health care after treatment for MPE was possible for 14 patients. The overall survival after initial diagnosis varied considerably from 14 months to 37 years, but the median survival after appearance of MPE was 10 months (range, 1-28). Systemic therapy for iodine-resistant recurrent thyroid disease may need to be considered as a treatment option for patients with MPE.

著者

Natsuko Watanabe Jaeduk Yoshimura Noh Ai Kozaki Ran Yoshimura Ai Yoshihara Nami Suzuki Masako Matsumoto Miho Fukushita Aya Kinoshita Azusa Aida Hideyuki Imai Shigenori Hiruma Toshu Inoue Kosuke Inoue Kiminori Sugino Koichi Ito

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.70, no.11, pp.1087-1096, 2023 (Released:2023-11-28)

参考文献数

40

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Appropriate administration of anti-inflammatory and immunosuppressive treatment (AIIST) is important for patients with Graves’ orbitopathy (GO). This study aimed to clarify the incidence and risk factors for GO treated with AIIST and propose a predictive score, among newly diagnosed Graves’ disease (GD) patients in Japan. A total of 1,553 GD patients who were newly diagnosed during the year 2011 were investigated. AIIST included local and/or systemic glucocorticoid administration and retrobulbar irradiation. A multivariable Cox proportional hazards model was used to investigate the risk factors for GO underwent AIIST during medical treatment, including at diagnosis, of GD. Then, a GO score was created by summing each point assigned to risk factors based on their coefficient obtained in the Cox model. AIIST was administered to 107 patients (6.9%). The risk factors and hazard ratios for GO underwent AIIST were: age (per 10 years), 1.32 (95% confidence interval: 1.16–1.50), p < 0.0001; TSH binding inhibitory immunoglobulin (TBII) (per 10 IU/L), 1.33 (1.15–1.54), p = 0.0001; and thyroglobulin antibody (TgAb) negativity, 2.98 (1.96–4.59), p < 0.0001. The GO score, ranging from 0 to 8 points, showed moderate performance (area under the curve: 0.71, cut-off value: 5 points, sensitivity: 0.76, specificity: 0.59, positive predictive value: 0.12, negative predictive value: 0.97). AIIST was performed for patients with active manifestations of GO in 6.9% of newly diagnosed GD patients. The risk factors for GO underwent AIIST were higher age, higher TBII, and TgAb negativity. The GO score based on these factors may be useful in managing GO.

著者

Marino Hiruma Natsuko Watanabe Takako Mitsumatsu Nami Suzuki Miho Fukushita Masako Matsumoto Ai Yoshihara Jaeduk Yoshimura Noh Kiminori Sugino Koichi Ito

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ22-0319, (Released:2022-10-05)

被引用文献数

2

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Graves’ disease has been reported to affect the clinical features of moyamoya disease (MMD), an occlusion of the circle of Willis. This study aimed to clarify the characteristics of MMD in patients with Graves’ disease. This was a single-center, retrospective study. The prevalence and clinical features of MMD patients among all patients with thyroid disease who visited Ito hospital from January 2005 to December 2019 were evaluated. The relationship between MMD and hyperthyroidism was analyzed in new-onset Graves’ disease patients during the same period. Of all 394,422 patients with thyroid disease, 88,180 had Graves’ disease, and 40 had MMD with Graves’ disease, i.e., the prevalence was 45.36 per 100,000 patients with Graves’ disease (0.0454%). The median age at onset of MMD was 39 years (interquartile range, 31–54 years), with a male to female ratio of 1:12. The most common time that MMD was diagnosed was within 1 year after the onset of Graves’ disease, in 9 of 40 patients (22.5%), and 19 of 40 patients (47.5%) underwent bypass surgery for MMD. In MMD with Graves’ disease, headache was the most frequent symptom, and ischemic types of stroke and bilateral lesions were common. Of 23,347 patients with new-onset Graves’ disease, 7 were diagnosed with MMD and the incidence of MMD was 5.94 patients per 100,000 person-years. Most patients developed MMD symptoms during hyperthyroidism. Although MMD is a rare condition, it should be noted that it can occur with Graves’ disease.

著者

伊藤 孝一 Koichi Ito

出版者

淑徳大学人文学部紀要委員会

雑誌

研究論集 (ISSN:21895791)

巻号頁・発行日

no.4, pp.109-118, 2019

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日本のテレビ放送が始まって65年。テレビはメディア・コミュニケーションの中心的な役割を担い、人々に大きな影響を与えてきた。テレビ番組の中で、報道やスポーツとならぶ大きな存在であり、大衆文化を先導してきたのがドラマである。「生ドラマ」と呼ばれる生放送から始まり、VTR機器類の進化、山田太一・向田邦子・倉本聰という「シナリオライター御三家」やこの後の有能なシナリオライターの登場により、テレビドラマはエンタテインメントを担うコンテンツとして大きく進展してきた。しかし、この数年、「俳優が出演を拒否する」「視聴率が取れない」「バラエティ番組枠に変更する」などという声が聞かれ、テレビドラマは不振と言われている。ドラマは「時代を映す鏡」といわれて久しいが、いま醸し出されている人々の意識、あるいは時代の空気感とドラマの創造性="クリエイティビティ"との関係に視点をおいて、現在のテレビドラマにおけるクリエイティビティについて論じる。

著者

Koichi Ito Emiko Chiba Noriko Oyama-Manabe Satoshi Washino Osamu Manabe Tomoaki Miyagawa Kohei Hamamoto Masahiro Hiruta Keisuke Tanno Hiroshi Shinmoto

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.mp.2020-0182, (Released:2021-05-15)

参考文献数

23

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Purpose: To assess the diagnostic performance of the tumor contact length (TCL) and apparent diffusion coefficient (ADC) for predicting extraprostatic extension (EPE) of prostate cancer with capsular abutment (CA).Methods: Ninety-three patients with biopsy-proven prostate cancer underwent 3-Tesla MRI, including diffusion-weighted imaging (b value = 0, 2000 s/mm2) and radical prostatectomy. Two experienced radiologists, blinded to the clinicopathological data, retrospectively assessed the presence of CA on T2-weighted imaging (T2WI). TCL on T2WI and ADC values were measured on detecting CA in prostate cancer. We used the receiver operating characteristic curves to assess the diagnostic performance of TCL and ADC values for predicting EPE.Results: CA was present in 58 prostate cancers among 93 patients. The cut-off value for TCL was 6.9 mm, which yielded an area under the curve (AUC) of 0.75. This corresponded to a sensitivity, specificity, and accuracy of 84.2%, 61.5%, and 69.0%, respectively. The cut-off value for ADC was 0.63 × 10–3 mm2/s, which yielded an AUC of 0.76. This, in turn, corresponded to a sensitivity, specificity, and accuracy of 84.2%, 59.0%, and 67.2%, respectively. The combined cut-off value of TCL and ADC yielded an AUC of 0.82. The specificity (84.6%) and accuracy (81.0%) of the combined value were superior to their individual values (P < 0.05).Conclusion: A combination of TCL and ADC values provided high specificity and accuracy for detecting EPE of prostatic cancer with CA.

著者

Noboru Hamada Jaeduk Yoshimura Noh Yasuyuki Okamoto Miki Ueda Toshiaki Konishi Toshimichi Fujisawa Koichi Ito Kunihiko Ito

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.57, no.7, pp.645-649, 2010 (Released:2010-07-30)

参考文献数

22

被引用文献数

6 10

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There is some debate over the clinical utility of measuring serum TgAb to assess the presence of thyroid autoimmunity. To clarify the relationship between TgAb levels and thyroid autoimmunity, a histological examination of thyroid tissue was carried out on unselected living individuals with detectable serum TgAb. 146 patients with a pathological diagnosis of follicular adenoma were selected as subjects. Focal lymphocytic infiltration (FLI) was defined as lymphocytic aggregates of more than 200 in number. A thyroid gland in which 0-1 FLI was observed in a few visual fields of low magnification (20 × 4) in thyroid tissue adjacent to a tumor was judged to be normal and a thyroid gland in which 2 or more FLI were observed was diagnosed as focal lymphocytic thyroiditis (FLT). Serum levels of TgAb and TPOAb were measured by radioimmunoassay. Out of the 146 patients, 18 had detectable serum TgAb and 16 had detectable serum TPOAb. All but one (i.e. 94%) of the 18 TgAb positive patients had FLT and 14 out of the 16 TPOAb positive patients had FLT. The sensitivity (17/32; 53.1%) and specificity (113/114; 99.1%) of TgAb for detecting FLT were higher than those (14/32; 43.7% and 112/114; 98.2%) of TPOAb, but the differences were not significant. In 9 patients who were TgAb positive (but TPOAb negative), 8 (88.9%) had FLT. These results throw doubt on the Laboratory medicine practice guidelines published in Thyroid 2003, in which measuring TgAb is not usually necessary for detecting autoimmune thyroid disease. At least measuring TgAb by sensitive assay is useful for assessing the presence of thyroid autoimmunity in Japan, an area with high iodine intakes.

著者

Yo Kunii Takashi Uruno Koji Mukasa Kenichi Sekiya Kenji Iwaku Akifumi Suzuki Kiminori Sugino Jaeduk Yoshimura Noh Koichi Ito

出版者

(社)日本内分泌学会

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.63, no.1, pp.21-27, 2016 (Released:2016-01-31)

参考文献数

20

被引用文献数

1 5

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In the event of a nuclear power plant accident, prophylactic administration of potassium iodide (KI) is recommended to prevent thyroid damage due to uptake of radioiodine. To assess the inhibitory effect of low-dose inorganic iodine on thyroidal radioactive iodine uptake (RAIU) in healthy adults without dietary iodine restriction, single or repeated doses of 10 mg inorganic iodine solution were given to 22 Japanese volunteers, 18 men and 4 women with the mean age of 35.7 years, between 2011 and 2013. Changes in urinary iodine excretion, thyroid function and 24-hour RAIU were also evaluated. The median 24-hour RAIU without iodine restriction was 13 % (range, 5-26 %). A single-dose of 10 mg inorganic iodine suppressed the median 24-hour RAIU measured one hour after iodine administration to 3 % (range, 1-7 %) and, in 90.9% of 22 participants their 24-hour RAIU was < 5 %. For seven participants given 10 mg of inorganic iodine daily for 14 days, the median 24-hour RAIU measured at 24 hours after the last administration of iodine was 6 % (range, 2-12 %), although the inhibitory effect was diminished in two participants. Serum thyroid stimulating hormone concentration was slightly elevated in three participants without decreased serum FT3 and FT4 levels. We conclude that a single-dose of 10 mg inorganic iodine is sufficient to inhibit RAIU in adults, although the inhibitory effect of repeated-dose on RAIU is diminished when KI is given once daily. The dose, duration or interval of iodine administration should be evaluated in iodine-sufficient regions in a future.

著者

Shuji SAKAI Koichi ITO Takafumi AOKI Takafumi WATANABE Hiroki UNTEN

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E98-D, no.10, pp.1818-1828, 2015-10-01

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Methods of window matching to estimate 3D points are the most serious factors affecting the accuracy, robustness, and computational cost of Multi-View Stereo (MVS) algorithms. Most existing MVS algorithms employ window matching based on Normalized Cross-Correlation (NCC) to estimate the depth of a 3D point. NCC-based window matching estimates the displacement between matching windows with sub-pixel accuracy by linear/cubic interpolation, which does not represent accurate sub-pixel values of matching windows. This paper proposes a technique of window matching that is very accurate using Phase-Only Correlation (POC) with geometric correction for MVS. The accurate sub-pixel displacement between two matching windows can be estimated by fitting the analytical correlation peak model of the POC function. The proposed method also corrects the geometric transformations of matching windows by taking into consideration the 3D shape of a target object. The use of the proposed geometric correction approach makes it possible to achieve accurate 3D reconstruction from multi-view images even for images with large transformations. The proposed method demonstrates more accurate 3D reconstruction from multi-view images than the conventional methods in a set of experiments.

著者

Yuichiro TAJIMA Kinya FUDANO Koichi ITO Takafumi AOKI

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E96-D, no.4, pp.826-835, 2013-04-01

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This paper presents a fast and accurate volume correspondence matching method using 3D Phase-Only Correlation (POC). The proposed method employs (i) a coarse-to-fine strategy using multi-scale volume pyramids for correspondence search and (ii) high-accuracy POC-based local block matching for finding dense volume correspondence with sub-voxel displacement accuracy. This paper also proposes its GPU implementation to achieve fast and practical computation of volume registration. Experimental evaluation shows that the proposed approach exhibits higher accuracy and lower computational cost compared with conventional method. We also demonstrate that the GPU implementation of the proposed method can align two volume data in several seconds, which is suitable for practical use in the image-guided radiation therapy.

著者

伊藤 晃一 イトウ コウイチ Koichi ITO

出版者

千葉大学教育学部授業実践開発研究室

雑誌

授業実践開発研究 (ISSN:18848818)

巻号頁・発行日

vol.2, pp.17-26, 2009-03

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子どもたちと学校に招かれた外国人とがなんらかのかかわりをするというような異文化交流の実践のほとんどは、今まで授業の中で行われていた。しかし筆者は、授業の中で行われる異文化交流の実践が、授業がもつ特徴によってむしろ制約されてしまい、本来の意味での異文化交流が出来ていないのではないかという問題意識を持つようになった。本研究は、授業の特徴が異文化交流の実践にどのような影響を及ぼしているのかを詳しく検討した上で、その問題点を指摘し、授業の枠組みをはずした場における異文化交流の実践を作成し、その成果と課題を考察し、学校における新しい異文化交流の可能性を見いだすことを目的としている。実践は、実践時間をあえて授業から切り離し、休み時間に行った。実践の成果としては、子どもたちが多様な仕方で外国人とかかわろうと試行錯誤する様子が見受けられ、それを休み時間に行った成果と結論づけた。一方で、今後このような実践を学校文化の中にどう位置づけていくのかということや、異文化交流ということばが、果たして客観的なことばとして機能するのかということや、子どもたちのかかわりを記述するとはどういうことかという問題も明らかになった。

著者

Naoki HAYASHI Satoru MONZEN Koichi ITO Tsuyoshi FUJIOKA Yukio NAKAMURA Ikuo KASHIWAKURA

出版者

Journal of Radiation Research Editorial Committee

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.53, no.2, pp.195-201, 2012 (Released:2012-04-17)

参考文献数

28

被引用文献数

8

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The present study aimed to estimate the clonogenic and differentiation potential of induced pluripotent stem (iPS) cells exposed to ionizing radiation. Compared with mouse hematopoietic stem/progenitor cells, iPS cells were less sensitive to radiation. To examine the effect of ionizing radiation on the early differentiation pathway of iPS cells, we assessed embryoid body (EB) formation. Although EB formation was observed at all radiation doses, EB diameter decreased in a radiation dose-dependent manner. At the same time, we analyzed the expression of genes specific to differentiation in the initial iPS cells and cells of EB. The expression of the endoderm marker Afp increased remarkably in cells of EB derived from non-irradiated iPS cells; however, in irradiated cells, this expression significantly decreased in a radiation dose-dependent manner. Further, the expressions of the pluripotent stem cell markers Nanog and Oct-4 and the early mesoderm marker Brachyury significantly decreased. The results of the present study suggest that radiosensitivity with regard to gene expression differs at various stages in the early differentiation pathways of iPS cells that lead to the formation of the 3 germ layers; the sensitivity is the highest in the genes expressed during the differentiation pathways of iPS cells, leading to the formation of the endoderm.

著者

Yukitoshi MAKIMURA Koichi ITO Masayoshi KUWAHARA Hirokazu TSUBONE

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1204110810, (Released:2012-04-13)

被引用文献数

4 8

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Enteritis has been recognized as a major symptom in domestic animals and human patients suffering from feed and food poisonings. The aim of the present study was to clarify the excitatory mechanism of the pelvic nerve afferent which may influence the occurrence of enteritis in response to nociceptive chemical stimuli of the colon in normal and abnormal rats with colitis induced by dextran sulfate sodium (DSS). The pelvic nerve afferent activity was markedly increased by colonic instillation of solution (0.5 ml) of acetic acid (5–25%) and capsaicin (100μg/ml). The nerve activity was augmented by colonic instillation of capsaicin to a greater extent in rats with DSS-induced colitis than in normal control rats. This augmented activity by capsaicin was more prominent at one day (DSS-1) than at 8 day (DSS-8) after the administration of DSS. The increased nerve activity caused by capsaicin in DSS-1 and DSS-8 was significantly inhibited by pretreatment with ruthenium red, which is a nonselective inhibitor of TRP channels of unmyelinated C-fibers (nociceptors). In conclusion, it was elucidated that the nociceptive function of the pelvic nerve was largely elevated at one day after DSS-induced colitis and such increased function was mostly mediated by TRP channels.