著者

Shigeto Fujimura Kunio Yoshioka Takashi Saito Mutsuto Sato Makoto Sato Yuuki Sakuma Yasuyuki Muramatsu

出版者

日本作物学会

雑誌

Plant Production Science (ISSN:1343943X)

巻号頁・発行日

vol.16, no.2, pp.166-170, 2013 (Released:2013-03-19)

参考文献数

13

被引用文献数

45

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Radionuclides were released into the environment as a consequence of the Fukushima Daiichi Nuclear Power Plant accident that occurred on 11 March 2011. Radiocesium at an abnormal concentration was detected in brown rice produced in paddy fields located in northern part of Fukushima Prefecture. We examined several hypotheses that could potentially explain the excessive radiocesium level in brown rice in some of the paddy fields, including (i) low exchangeable potassium content of the soil, (ii) low sorption sites for cesium (Cs) in the soil, and (iii) radiocesium enrichment of water that is flowing into the paddy fields from surrounding forests. The results of experiments using pots with contaminated soil indicated that the concentration of radiocesium in rice plants was decreased by applying potassium or clay minerals such as zeolite and vermiculite. The obtained results indicated that high concentrations of radiocesium in rice are potentially a result of the low exchangeable potassium and sorption sites for Cs in the soils. Application of potassium fertilizer and clay minerals should provide an effective countermeasure for reducing radiocesium uptake by plants. Radiocesium-enriched water produced by leaching contaminated leaf litter was used to irrigate rice plants in the cultivation experiments. The results indicated that the radiocesium concentrations in rice plants increased when the radiocesium-enriched water was applied to the potted rice plants. This indicated the possibility that the radiocesium levels in brown rice will increase if the nuclide is transported with water into the rice paddy fields from surrounding forests.

著者

斎藤 喬 サイトウ タカシ Takashi Saito

出版者

豊橋技術科学大学

雑誌

雲雀野 : 豊橋技術科学大学人文科学系紀要 = The lark hill : bulletin of the School of Humanities, Toyohashi University of Technology (ISSN:0388757X)

巻号頁・発行日

no.41, pp.27-39, 2019

著者

Yayoi Ueda Shoji Asakura Sae Wada Takashi Saito Tomofumi Yano

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.9136-21, (Released:2022-05-31)

参考文献数

15

被引用文献数

12

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A patient with follicular lymphoma treated with obinutuzumab and bendamustine experienced prolonged coronavirus disease-2019 (COVID-19). One month after the symptoms transiently improved, the patient experienced exacerbated COVID-19 symptoms. The patient recovered from COVID-19 with remdesivir and dexamethasone and was discharged 77 days after the disease onset. The patient completed a primary series of SARS-CoV-2 vaccinations on day 176, but the anti-spike protein IgG was not detected later. A careful observation to detect any subsequent relapse of COVID-19 symptoms is necessary in immunocompromised patients. Chemotherapy should be based on the disease status and type of lymphoma.

著者

Yuko Yamakage Hitomi Tsuiji Takao Kohno Himari Ogino Takashi Saito Takaomi C. Saido Mitsuharu Hattori

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.42, no.3, pp.354-356, 2019-03-01 (Released:2019-03-01)

参考文献数

16

被引用文献数

8

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Reelin is a secreted protein that antagonizes the deposition and toxicity of amyloid β peptide (Aβ). Therefore, augmentation of Reelin activity may ameliorate Alzheimer’s disease (AD). We have recently reported that a disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAMTS-3) cleaves and inactivates Reelin in the mouse brain. In the present study, we investigated the effect of reducing ADAMTS-3 on deposition of Aβ by crossbreeding drug-inducible ADAMTS-3 conditional knock-out (cKO) mice with “next-generation” AD model mice. We found that reducing ADAMTS-3 inhibited deposition of Aβ significantly in AppNL-F mice, which produce human wild-type Aβ. On the other hand, reducing ADAMTS-3 had no effect in AppNL-G-F mice, which produce the Arctic mutant Aβ (E22G) that forms protofibrils more efficiently than does wild-type Aβ. Thus, the findings suggest that the administration of an inhibitor against ADAMTS-3 will prevent the progression of AD pathology caused by deposition of wild-type Aβ.

著者

Yuki Takigawa Keiichi Fujiwara Takashi Saito Takamasa Nakasuka Taichi Ozeki Sachi Okawa Kenji Takada Yoshitaka Iwamoto Hiroe Kayatani Daisuke Minami Ken Sato Miki Nagao Takuo Shibayama

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.1454-18, (Released:2018-10-17)

参考文献数

25

被引用文献数

10

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A 66-year-old man was transferred to our hospital for pneumonia that was resistant to sulbactam/ampicillin and levofloxacin therapy. Chest computed tomography showed the rapidly progressive formation of multiple cavities. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated, and the patient was diagnosed with necrotizing pneumonia caused by community-acquired MRSA (CA-MRSA). The MRSA strain had type IV staphylococcus cassette chromosome mec and genes encoding Panton-Valentine leucocidin (PVL). CA-MRSA necrotizing pneumonia with the PVL gene is rare; only three cases have been previously reported in Japan. We administered anti-MRSA antibiotics and the patient achieved complete clinical and radiological improvement.

著者

Kazuya Tamura Yuya Ueda Takashi Saito Ryo Goto Naoki Yamada Kiyomasa Nakatsuka Kazuaki Uchida Kana Horibe Kenta Saeki Haruhi Encho Masato Tezuka Mao Mukaijo Rei Ono

出版者

The Japanese Society of Physical Fitness and Sports Medicine

雑誌

The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)

巻号頁・発行日

vol.12, no.5, pp.133-139, 2023-09-25 (Released:2023-09-13)

参考文献数

34

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Outdoor play during childhood is vital for physical, cognitive, and social development. Outdoor play is influenced by friends, though the relationship between outdoor play and the number of close friends is not clear. This study aimed to investigate the association between peer group size and outdoor play among children aged 9–12 years. This study was cross-sectional in design. We recruited fourth- to sixth-grade children from two public elementary schools. Outdoor play contents and duration on weekdays were collected via a questionnaire, and the total duration of outdoor play on five weekdays was calculated. We asked the children to nominate up to 10 of their closest friends. We calculated the peer group size as the total number of reciprocal closest friends for each child. A multivariate linear regression analysis was conducted to investigate the association between peer group size and outdoor play duration, adjusted for gender, grade, school, body mass index, sports club participation, and screen time. This study included 291 children (137 girls, mean age: 10.6 ± 1.0 years). The peer group size was associated with outdoor play duration after adjusting for confounding factors (β: 0.18, 95% CI: 0.07-0.30). This study revealed that children aged 9–12 years, with larger peer group size showed a significantly longer duration of outdoor play.

著者

Kouji Kida Yasuhiro Matsuoka Tetsuya Shimoda Hiroaki Matsuoka Haruto Yamada Takashi Saito Osamu Imataki Norimitsu Kadowaki Keita Noguchi Ken Maeda Yasushi Mochizuki Toshio Kishimoto

出版者

National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee

雑誌

Japanese Journal of Infectious Diseases (ISSN:13446304)

巻号頁・発行日

vol.72, no.5, pp.356-358, 2019 (Released:2019-09-19)

参考文献数

10

被引用文献数

70

著者

Masahiro IIJIMA Kyotaro KAWAGUCHI Naohiko KAWAMURA Shuichi ITO Takashi SAITO Itaru MIZOGUCHI

出版者

日本歯科理工学会

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.36, no.4, pp.461-468, 2017-07-25 (Released:2017-07-26)

参考文献数

30

被引用文献数

14

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We investigated single application of pastes containing a surface reaction-type pre-reacted glass-ionomer (S-PRG) filler on enamel demineralization. Human enamel blocks were polished using pastes containing S-PRG filler (0, 5, and 30%) and immersed in demineralizing solution for 5 days with daily change of solutions. The pH measurement and nanoindentation testing was carried out during the immersion period, and the enamel surfaces were examined using scanning electron microscopy and atomic force microscopy. A non-fluoride paste and a hydroxyapatite-containing paste were used for comparison. The specimens polished with the S-PRG filler-containing paste exhibited acid-neutralizing properties, which became stronger with an increasing S-PRG filler content. Following immersion in the demineralizing solution, specimens polished with the S-PRG filler-containing paste exhibited significantly greater hardness and elastic modulus values than those polished with the other pastes and exhibited a smoother surface than did the other specimens. Pastes containing S-PRG filler inhibits the demineralization of enamel.