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出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.54, no.2, pp.124-124, 2014 (Released:2014-03-28)

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著者
河野 敬一
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.48, no.4, pp.213-213, 2008 (Released:2008-07-25)
著者
中岡 保夫
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.28, no.4, pp.194-197, 1988-07-25 (Released:2009-05-25)
参考文献数
12

Mechano-, thermo- and photo-stimulation of Paramecium cell elicits changes in the membrane potential called receptor potentials. The receptor potentials are caused by modulating ionic conductances of specific channels localized on the cell surface.
著者
福森 義宏 田岡 東
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.54, no.1, pp.011-014, 2014 (Released:2014-01-29)
参考文献数
19
被引用文献数
1

Magnetosomes synthesized in magnetotactic bacteria function as a cellular compass to navigate along the Earth’s magnetic field. The magnetosome contains various types of specific associated proteins. Most of the magnetosome-associated proteins are encoded in gene clusters within a genetic “magnetosome island,” which is essential for the synthesis of magnetosomes. Our atomic force microscopy studies indicated that the thickness of the organic layer wrapped around the magnetite crystal was ~7 nm, and magnetosome-associated protein MamA was localized at the surface of the organic layer. In this review we present recent progress on “Structure and Function of Magnetosomes” and propose the structural model of magnetosomes in the cell.
著者
古賀(巽) 理恵 古賀 信康
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.53, no.4, pp.190-193, 2013 (Released:2013-07-25)
参考文献数
15
被引用文献数
3

Protein folding occurs because the native interactions collectively outweigh non-native interactions, resulting in funnel-shaped energy landscapes. The funnel-shaped landscapes of natural proteins are rugged due to evolution for function or neutral drift. We describe an approach to designing ideal protein structures stabilized by consistent local and non-local interactions. The approach is based on rules relating local structures to tertiary motifs, which make possible the design of strongly funneled energy landscapes. Guided by these rules, we succeeded in designing five ideal alpha-beta protein structures with different topologies completely from scratch. These results illuminate how the folding funnels of natural proteins arise.
著者
土居 洋文
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.32, no.4, pp.216-220, 1992-07-25 (Released:2009-05-25)
参考文献数
23
著者
岡本 尚
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.15, no.3, pp.113-124, 1975-05-25 (Released:2009-05-25)
参考文献数
40
被引用文献数
1 1

The conception of "electrogenic ion pump", actively separating charges across cell membranes, has been recently developed as a concequence of the recognition of the more intimate relationship between the mechanism generating resting membrane potential and the energy metabolism of the cell than formerly supposed. Existence of the resting potential larger than the equilibrium potential of any major permeable ion across cell membrance supports the above view and is regarded as a safety criterion for electrogenic activity. Another criterion, rapidity of the depolarization caused by the application of inhibitory reagents or conditions for energy metabolism, is examined critically taking several experimental results for instances. The investigations towards the energy sources for electrogenic activity and several hypothetical models for electrogenic ion pump are also reviewed. The ion which is transported across membrane by the electhogenic mechanism seems to be H+ in most plant cells, though in some cases Cl- is a possible candidate. The role of H+ in plant cells as a substitute of Na+ in the case of animal cells is reviewed with special reference to the "co-transport" of organic molecules and also from the view point of origin and evolution of the membrane transport systems.
著者
大畑 健次 小西 慶幸 瀬藤 光利
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.50, no.2, pp.080-083, 2010 (Released:2010-03-30)
参考文献数
15

Imaging mass spectrometry (IMS) visualizes the distribution of a wide range of biomolecules in cells and tissue sections. IMS can analyze a variety of biomolecules including unexpected metabolites, without labels in a non-targeted way. We developed AP-MALDI (atmospheric pressure matrix assisted laser desorption/ionization) which is equipped with an atmospheric pressure ion-source chamber. It allows us to analyze flesh samples with minimal loss of intrinsic water or volatile compounds.
著者
水谷 泰久 水野 操
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.51, no.1, pp.010-013, 2011 (Released:2011-01-26)
参考文献数
18

Time-resolved resonance Raman spectroscopy is able to provide site-selective information on protein dynamics. In this review, we will describe our apparatus of picosecond time-resolved ultraviolet resonance Raman spectroscopy and recent application to protein dynamics of bacteriorhodopsin.
著者
水谷 泰久
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.47, no.5, pp.288-294, 2007 (Released:2007-09-28)
参考文献数
27
被引用文献数
3 1 3

In numerous biological processes, the ensuing protein structural changes accompanying a reaction at a specific site must spatially extend to the mesoscopic dimensions of the protein to achieve a biological function. The molecular mechanism of cooperativity in oxygen binding of hemoglobin is one of the classical problems in this aspect. This review describes our recent works on protein dynamics of myoglobin and hemoglobin by using time-resolved resonance Raman spectroscopy.
著者
内山 郁夫
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.42, no.6, pp.266-269, 2002 (Released:2002-11-23)

MBGD is a database system for making use of rapidly accumulating microbial genome sequences through comparative analysis. The basic function of MBGD is to create an orthologous gene classification table, which comprises sets of "equivalent" genes among multiple genomes. In MBGD, classification tables can be created on demand with specified set of organisms and parameters. This feature becomes important to understand diversity of genomes using almost a hundred genome sequences now available.