著者
天竺桂 弘子 佐藤 令一
出版者
東京農工大学
雑誌
挑戦的研究(開拓)
巻号頁・発行日
2020-07-30

宿主体内への侵入は、多胚性寄生蜂において寄生成功の必須要件である。この侵入において、多胚性寄生蜂の桑実胚は宿主組織内に損傷を与えることなく侵入し、むしろ宿主は桑実胚を積極的に迎え入れる。このような組織親和的侵入は、一般的に動物界で広く知られる遠縁種間の急性型移植拒絶反応を回避するユニークな現象で、その仕組みとして分子擬態が示唆されてきた。本研究では申請者らがこれまでに多胚性寄生蜂の胚発生期の遺伝子発現解析で得られた情報を基に、組織親和的侵入の仕組みを解明することを目的とする。
著者
佐藤 令奈
出版者
社会学研究会
雑誌
ソシオロジ (ISSN:05841380)
巻号頁・発行日
vol.58, no.1, pp.19-34,185, 2013

This study clarifies how the problem of atopic dermatitis in Japan developed criticism of modernity or modern medicine using discourse analysis of mass media and discussing the consequences and significance of this criticism. Atopic dermatitis initially emerged as an illness with causes attributed to modern lifestyles and was commonly referred to as a 'civilization disease. 'Although difficult to treat, many treatments recommended diet control for patients. Conversely, citing risks associated with diet control, some physicians recommended pharmacological treatment, in particular, the use of corticosteroids. However, pharmacological treatments were criticized since they present the risk of side effects. Consequently, patients developed critical views toward modern medicine from the viewpoints of lack of informed consent and the adequacy of using corticosteroids. Physicians countered this criticism against modern medicine by advocating "discussion of atopic dermatitis as a medical business", which is a discussion of the confidence trick against the patients of atopic dermatitis and prepared the standard treatment. Recently, patients seem to be accepting the physicians' claims. It is evident from this discussion that the criticism of modern medicine in the context of the physician–patient relationship, like the lack of informed consent or interventional pharmacological treatments, is losing effectiveness. Now is the time for proper criticism of modern medicine in order to restructure its effectiveness by revising the significance of the self-transformation of the modern physician.