著者

今井 俊吾 阿部 真也 松井 洸 柏木 仁 佐藤 夕紀 武隈 洋 吉町 昌子 菅原 満

出版者

一般社団法人 日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.24, no.2, pp.75-87, 2022-08-31 (Released:2022-10-11)

参考文献数

17

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Objective: In our previous study, we revealed that articles on "dangerous drugs" in weekly magazines are inadequate and incomplete with respect to scientific validity, and that there may be many aspects that need to be improved. Next, the extent to which medical professionals, including doctors, pharmacists, and nurses, received consultations by patients owing to such media reports and what countermeasures are implemented requires clarification. In the present study, as a first step, we performed a questionnaire survey of community pharmacists to clarify the occurrence of such consultations.Methods: A questionnaire survey was conducted among 698 community pharmacists. The survey was conducted over 10 days from December 8 to 17, 2021.Results: Out of the 698 community pharmacists, 545 responded (response rate: 78.1%). Of these, 323 (59.3%) had experienced consultations from patients owing to media reports on the dangers of drugs. Of the 323 respondents, 215 (66.6%) had experienced these consultations less than five times. In contrast, 83 respondents (25.7%) reported more than 10 such consultations. Of the 545 respondents, 190 (34.9%) responded that they routinely perform measures to deal with media reports on the dangers of drugs. The most common routine measure was the "regular checking of various media sources (including preparation of responses when receiving consultation requests)."Conclusion: Our results indicated that more than half of the community pharmacists had experienced receiving consultations from patients, although only approximately 30% were adopting routine measures. This suggests that community pharmacists have been affected to some extent by these media reports, and that further countermeasures need to be implemented.

著者

今井 俊吾 柏木 仁 佐藤 夕紀 武隈 洋 菅原 満

出版者

一般社団法人 日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.24, no.1, pp.1-10, 2022-05-31 (Released:2022-06-11)

参考文献数

11

被引用文献数

1

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Objective: Recently, special features on “dangerous” prescription drugs have been frequently published in few mass media platforms, such as weekly magazines. However, to our knowledge, there have been no prior studies, systematically organizing and evaluating the contents of these articles (e.g., drugs and their side effects that are reported). In this study, we aimed to evaluate the relevance of the information on “dangerous drugs” that was published in weekly magazines using the modified “Media Doctor” instrument.Methods: We extracted articles on “dangerous” prescription drugs from 10 weekly magazines for which the table of contents of previous issues are available on their official websites. Information regarding the target drugs and their classifications was compiled and organized. The relevance of the extracted news articles was assessed by two independent evaluators. The evaluation index was based on the modified “Media Doctor” instrument, and 9 evaluation criteria were used to assign the following categories: satisfactory, unsatisfactory, or not applicable.Results: A total of 1,064 articles were screened, and 19 articles were selected for further evaluation. A total of 179 drugs (belonging to 34 drug classes) were listed. The most frequently mentioned class of drugs included hypnotics and sedatives, and the most frequently listed was triazolam. Of the 19 articles, 11 had zero items that were judged satisfactory by both the evaluators. The number of unsatisfactory items was widely distributed, but in 11 of the 19 articles, five and more items were judged unsatisfactory by both the evaluators.Conclusion: We revealed that a wide variety of drugs have been termed as “dangerous” by weekly magazines. Additionally, we found that these articles were inadequate and incomplete with respect to scientific validity, and that there are many aspects that require further improvement.

著者

今井 俊吾 難波 正志 柏木 仁 佐藤 夕紀 武隈 洋 菅原 満

出版者

一般社団法人 日本薬局学会

雑誌

薬局薬学 (ISSN:18843077)

巻号頁・発行日

pp.nt.2020-0025, (Released:2021-03-10)

参考文献数

10

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薬剤師は安全な薬物療法の提供のために,患者から必要な情報を「聞き取る」ことが重要である.しかし,薬局薬剤師の「聞き取り」に対し,一部の一般市民は厳しい視線を投げかけており,患者の理解を促すためのエビデンス構築が急務である.本研究は「患者への聞き取り」に基づき実施された疑義照会に着目し,その実態解明と医療安全への貢献度評価を試みた.解析には北海道大学病院の近隣薬局の疑義照会データを用いた.その結果,聞き取りに基づく疑義照会は「薬学的疑義照会の 33.3%を占め,高い許諾割合(98.5%)を有し,用法や用量などの疑義照会分類において,医療安全への貢献度が高い」ことが見いだされた.また,このうち「医師からの説明と処方内容が食い違う」ことが発端となった事例が,特に医療安全へ貢献していることが示された.「患者への聞き取り」に基づく疑義照会の有用性を広く調査するための基礎となる知見が創出された.

著者

武隈 洋 高地 里佳 石坂 悠 佐藤 夕紀 鷲見 正人 菅原 満

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.40, no.3, pp.135-146, 2014-03-10 (Released:2015-03-10)

参考文献数

20

被引用文献数

3

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This study determined the effects of long-term storage under various conditions after opening press through package (PTP) sheets on the stability of each tablet formula of statin for treatment of dyslipidemia and clarified the difference in stability between brand-name drugs and generic drugs.It was demonstrated that opened Crestor® tablets were stable for one year under the conditions of diffused light at room temperature and shielded light at room temperature. Although the content of rosuvastatin in ground Crestor® tablets was greatly decreased after only 1 month under the condition of diffused light, it was stable for at least 3 months under shielded light, indicating that shielded light is necessary for storage of ground Crestor® tablets. Of the four tablet formulae of simvastatin tested, only Lipola®M was within the stability standards after storage for 6 months under all conditions. The other tablet formulae of simvastatin showed changes in hardness or elution pattern even under the condition of shielded light at room temperature, indicating that care is needed in preparing one-dose packages of these formulae. Four tablet formulae of pravastatin used in this study were stable for 6 months under shielded light at room temperature. It was also found that three of the five formulae with decreasing elution velocity contained crospovidone and that the other formulae contained no crospovidone. This decrease in elution velocity appears to be due to reduction in porosity of the tablet caused by high humidity.

著者

今井 俊吾 難波 正志 柏木 仁 佐藤 夕紀 武隈 洋 菅原 満

出版者

一般社団法人 日本薬局学会

雑誌

薬局薬学 (ISSN:18843077)

巻号頁・発行日

vol.13, no.1, pp.68-78, 2021 (Released:2021-04-27)

参考文献数

10

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薬剤師は安全な薬物療法の提供のために,患者から必要な情報を「聞き取る」ことが重要である.しかし,薬局薬剤師の「聞き取り」に対し,一部の一般市民は厳しい視線を投げかけており,患者の理解を促すためのエビデンス構築が急務である.本研究は「患者への聞き取り」に基づき実施された疑義照会に着目し,その実態解明と医療安全への貢献度評価を試みた.解析には北海道大学病院の近隣薬局の疑義照会データを用いた.その結果,聞き取りに基づく疑義照会は「薬学的疑義照会の 33.3%を占め,高い許諾割合(98.5%)を有し,用法や用量などの疑義照会分類において,医療安全への貢献度が高い」ことが見いだされた.また,このうち「医師からの説明と処方内容が食い違う」ことが発端となった事例が,特に医療安全へ貢献していることが示された.「患者への聞き取り」に基づく疑義照会の有用性を広く調査するための基礎となる知見が創出された.

著者

伊藤 綾子 五十嵐 清治 倉重 多栄 佐藤 夕紀 藤本 正幸 西平 守昭 松下 標 青山 有子 平 博彦 丹下 貴司

出版者

The Japanese Society of Pediatric Dentistry

雑誌

小児歯科学雑誌 (ISSN:05831199)

巻号頁・発行日

vol.44, no.4, pp.591-597, 2006

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含歯性嚢胞は歯原性嚢胞では歯根嚢胞に次いで多く見られる。一般的には未萌出または埋伏永久歯の歯冠に由来して発生するが,原因埋伏歯は正常歯胚であることがほとんどで,過剰歯に由来する含歯性嚢胞は比較的少ない。今回,我々は全身的問題から抜去を行わず経過観察していた上顎正中部の逆性埋伏過剰歯が嚢胞化し,定期検診の中断期間に急速に増大し,顔貌の腫脹まで来した含歯性嚢胞の症例を経験したので報告する。<BR>症例は13歳の男児で,既往歴として生後間もなくWilson-Mikity症候群の診断にて入院加療を受け,その後にてんかん,脳性麻痺,および精神発達遅滞と診断された。患児の埋伏過剰歯は当科で10歳時に発見されたが,全身状態が不良のため抜去を行わず経過観察を行っていた。その後,定期検診受診が途絶え1年3か月後に,過去数か月間で徐々に上顎右側前歯唇側歯槽部が腫脹してきたことを主訴に再来初診となった。口腔内診査では上顎左側前歯部歯槽部に青紫色の腫脹を認め羊皮紙様感を触知した。エックス線診査では上顎前歯部に1本の逆性埋伏過剰歯を含む単房性の境界明瞭な透過像を認めた。局所麻酔下に嚢胞と埋伏過剰歯の摘出術を施行したが,術後17日目に術部感染を来したため抗菌薬投与と局部の洗浄を継続し消炎・治癒に至った。術後2か月の経過は良好である。<BR>本例のように何らかの理由により埋伏過剰歯抜去が困難な場合は,その変化を早期に発見するために定期的,かつ確実な画像診断を含む精査が必須であると考えられた。