著者

小嶋 秀樹 仲川 こころ 安田 有里子

雑誌

情報処理

巻号頁・発行日

vol.49, no.1, pp.36-42, 2008-01-15

著者

宮本 裟也 佐藤 仁 栗原 祐史 田中 元博 稲田 大佳暢 堅田 凌悟 守谷 崇 安田 有沙 代田 達夫

出版者

特定非営利活動法人 日本顎変形症学会

雑誌

日本顎変形症学会雑誌 (ISSN:09167048)

巻号頁・発行日

vol.31, no.4, pp.197-203, 2021 (Released:2021-12-22)

参考文献数

23

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Acromegaly is an endocrine disease caused by excessive secretion of growth hormone (GH) after the end of the growth period, due to a pituitary adenoma. Mandibular prognathism, tongue hypertrophy, and bulging of the eyebrow arch are observed in the maxillofacial region. We describe a case with acromegaly for which surgical orthodontic treatment was performed after excision of the pituitary adenoma. A 47-year-old woman who became aware of enlargement of the size of the hands and feet from 35 years old was diagnosed with acromegaly by the Department of Neurosurgery because of a high GH level and a pituitary tumor on MRI. In September 2014, chemotherapy was performed after tumor resection via the nasal cavity. In March 2016, she was referred to the Department of Orthodontics of our hospital for further examination and treatment of malocclusion. Overjet and overbite were −5.0mm and +2.5mm, respectively. The occlusal relationship of the molars was Angle class Ⅲ. Angular analysis of lateral cephalometric analysis showed SNA: 80.0°, SNB: 77.0°, ANB: 3.0°, and FMA: 37.9°. Mandibular prognathism was diagnosed based on a Wits appraisal of −7.1. Since there was no clinical activity of acromegaly and hypertrophy of the hard and soft tissues due to acromegaly had stopped, and serum insulin-like growth factor-1 was well controlled by chemotherapy, orthognathic treatment was started in April 2016 and bimaxillary surgery was performed in January 2019. The occlusal relationship was stable and there was no recurrence at 2 years after the surgery. Since acromegaly has various complications, it is necessary to create a treatment plan considering the complications, and to perform extended follow-up due to the potential for recurrence of the disease.

著者

武蔵 博文 山田 智子 肥田 幸恵 安田 有紀 富田 大輔 鷹田 薫

出版者

富山大学

雑誌

教育実践研究 : 富山大学人間発達科学研究実践総合センター紀要 (ISSN:18815227)

巻号頁・発行日

vol.1, pp.15-27, 2006-12

著者

小川 秀治 伊藤 隆 佐藤 行 鎌田 久祥 安田 有 渡部 満

出版者

日本家畜臨床学会

雑誌

日本家畜臨床学会誌 (ISSN:13468464)

巻号頁・発行日

vol.29, no.1, pp.1-5, 2006

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分娩後における乳清及び血清中免疫グロブリンG(IgG)濃度、豚萎縮性鼻炎(AR)、豚丹毒(SE)凝集抗体価の経時的推移を、母豚24頭を用いて調査した。乳清中IgGは、分娩0日が最も高く、42.5mg/mlと血清IgGの約3倍の値を示した。この後16日までは血清と同レベルで推移し、以降低下し20日で血清の半分になった。乳清中のAR抗体およびSE抗体は、それぞれ分娩後20日、分娩後10日まで検出可能であった。豚オーエスキー病ラテックス凝集抗体を、ワクチン接種豚の乳清38検体、未接種豚の乳清23検体を用いて調査した。ワクチン接種豚の乳清中抗体は分娩0日の9検体全てが陽性を示し、10日後の2検体も陽性を示した。酵素抗体法(ELISA)検査では、凝集抗体陽性の検体は全例ワクチン抗体と判断された。未接種豚の乳清23検体は全て抗体陰性であった。なお、野外抗体陽性6例の検査では、乳清中の抗体は血清と同じく野外抗体と判断された。<BR>初乳は血清と同様の抗体検査が可能であり、初乳を用いた抗体検査は繁殖母豚群の抗体スクリーニングや疾病清浄化に向けて有効な方法と考えられた。

著者

栗原 祐史 勝田 秀行 山口 徹太郎 安田 有沙 塩竃 素直 佐藤 仁 斉藤 芳郎 鴨志田 慎之助 鎌谷 宇明 代田 達夫

出版者

特定非営利活動法人 日本顎変形症学会

雑誌

日本顎変形症学会雑誌 (ISSN:09167048)

巻号頁・発行日

vol.27, no.1, pp.17-23, 2017-04-15 (Released:2017-05-02)

参考文献数

9

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We report two cases of genioplasty performed using a navigation system. In recent years, virtual orthognathic surgeries have been performed using simulation software with data from preoperative computed tomography (CT), and the osteotomy design, direction and distance of bony segment movement have been established. Despite the accuracy of simulations using three-dimensional CT data, results obtained from simulations cannot be effectively applied to clinical practice unless comparisons can be made to actual surgery. We report our experience of performing genioplasty using simulation software with preoperative CT data, and established the osteotomy design as well as the direction and distance of bony segment movement. Simulation-guided navigation osteotomy was performed with reference to simulation results transferred to the navigation system. A reference antenna was attached to the head of the patient using a headband. Next, interfacing laser registration was performed. Osteotomy was then performed along the osteotomy line drawn on the chin bone surface using piezosurgery and a tracker, and the bone segment was mobilized by down-fracture using a bone saw. Using the image of the simulated repositioned bone segment shown on the navigation system screen, the bone segment was moved to the determined position and fixed. Our results suggest that use of a navigation system allows safer, more precise genioplasty.