著者

小林 良夫 Nagao Kobayashi

雑誌

東海女子短期大学紀要 = The journal of Tokai Women's Junior College (ISSN:02863170)

巻号頁・発行日

vol.20, pp.167-178, 1994-03-31

著者

小林 良夫

出版者

東海学院大学・東海女子短期大学

雑誌

東海女子短期大学紀要 (ISSN:02863170)

巻号頁・発行日

vol.22, pp.131-138, 1996-03-31

著者

小林 良夫

出版者

東海学院大学・東海女子短期大学

雑誌

東海女子短期大学紀要 (ISSN:02863170)

巻号頁・発行日

vol.20, pp.167-178, 1994-03-31

著者

林 良夫

出版者

社団法人 日本口腔外科学会

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.57, no.5, pp.234-237, 2011-05-20 (Released:2014-05-22)

参考文献数

8

---

Primary Sjören’s syndrome (SS) is an autoimmune disorder characterized by lymphocytic infiltrates and destruction of the salivary and lacrimal glands, leading to clinical symptoms of dryness of the mouth and eyes. Autoreactive T cells bearing CD4 molecule may recognize unknown self antigen, triggering autoimmunity in the salivary and lacrimal glands. Recent evidences suggest that the apoptotic pathway plays a central role in tolerazing T cells to tissue-specific self antigen including 120KD α-fodrin, and may drive the autoimmune phenomenon. Cleavage of certain autoantigens during apoptosis may reveal immunocryptic epitopes that could potentially induce autoimmune response. It is now evident that the interaction of Fas with FasL regulates a large number of pathophysiological process of apoptosis including autoimmune diseases. Our data imply that tissue-specific apoptosis and caspase-mediated α-fodrin proteolysis are involved in the progression of autoimmune lesions in SS. We found that retinoblastoma-associated protein RbAp48 overexpression induces apoptosis in the salivary glands caused by estrogen deficiency. The studies reviewed the pathology and molecular mechanisms on the development of SS.

著者

林 良夫 石丸 直澄

出版者

医歯薬出版

雑誌

医学のあゆみ (ISSN:00392359)

巻号頁・発行日

vol.206, no.11, pp.855-858, 2003-09-13

著者

小林 良夫 能美 隆 下池 洋一 上野 浩志 前川 麻弥 鈴木 克裕 川本 範之 山地 松夫 佐藤 隆

出版者

日本質量分析学会

雑誌

Journal of the Mass Spectrometry Society of Japan (ISSN:13408097)

巻号頁・発行日

vol.51, no.1, pp.205-215, 2003 (Released:2007-10-16)

参考文献数

4

被引用文献数

3 2

---

The purpose of this study is to estimate the amounts of kerosene poured at the scene of arson. Several analytical methods have been carried out to detect kerosene in fire debris. There is no study to compare the methods quantitatively. First we discussed comparison about several analytical methods, and got the conclusion that the most sensitive method was found to be the analysis using gas chromatography/mass spectrometry (GC/MS) after extracting by ether. The detection limit of this methed was 0.05 µg/g.The kerosene concentration of tatami had an effect on the condition of combustion. We estimated the diffusion speed of kerosene sprinkled on tatami. We conducted experiments to check the condition of tatami burning, due to the amount of kerosene. Furthermore, we showed the evidence to get fire debris from the inside not the surface to get information about the kerosene amount.

著者

布袋屋 智朗 林 英司 長山 勝 柳 久美子 林 良夫

出版者

Japanese Society of Oral and Maxillofacial Surgeons

雑誌

日本口腔外科学会雑誌 (ISSN:00215163)

巻号頁・発行日

vol.43, no.11, pp.840-842, 1997-11-20

参考文献数

13

被引用文献数

9 2

---

Vascular leiomyoma is a benign tumor of smooth muscle that mainly occurs in the hands and legs. However, it rarely occurs in the oral cavity.<BR>A case of vascular leiomyoma of the buccal mucosa is reported. A 73-year-old woman visited our department because of a swelling in the buccal mucosa. CT examination revealed a smooth tumorous lesion in the left buccal mucosa. The clinical diagnosis was a benign tumor, and enucleation of the tumor was performed. The histopathological diagnosis was vascular leiomyoma.