2 0 0 0 OA I-B-11 夏バテ実験モデルと六君子湯の効果
1 0 0 0 OA 京都薬科大学における学部生を対象とした医療薬学実習
- 著者
- 高良 恒史 大西 憲明 堀部 紗世 橋詰 勉 金澤 治男 横山 照由
- 出版者
- 一般社団法人日本医療薬学会
- 雑誌
- 医療薬学 (ISSN:1346342X)
- 巻号頁・発行日
- vol.29, no.1, pp.77-82, 2003-02-10 (Released:2011-03-04)
- 参考文献数
- 12
- 被引用文献数
- 3 3
For the development of a practical training system to effectively teach sterilization techniques, we conducted on unregistered questionnaire survey of the undergraduate student's view about the training practice for glass ample cutting, and then evaluated and discussed the introduction to practical training of pharmaceutical health care and sciences for the third-grade undergraduate students. Among 96 third-grade undergraduate students, 54 students (56%) had some experience in cutting glass amples while the remaining students did not. Twenty-six of the 54 students with some experience (48%) had some anxiety regarding glass ample cutting, while only 13 of the 42 inexperienced students (31 %) had such anxiety. Twelve of the 13 inexperienced students overcame some anxiety against glass ample cutting. Moreover, 87 of 96 students (91%) considered that receiving practice in glass ample cutting was necessary for them. Consequently, the training programs on glass ample cutting were found to be appropriate and useful for students to develop sufficient practical skills and accurate ability in sterilization techniques. As a result, we are now preparing to introduce a training program for glass ample cutting in addition to the regular practical training of pharmaceutical health care and sciences at Kyoto Pharmaceutical University.
1 0 0 0 OA 京都薬科大学における学部生を対象とした医療薬学実習の現状と今後の課題
- 著者
- 高良 恒史 大西 憲明 橋詰 勉 金澤 治男 横山 照由
- 出版者
- 一般社団法人日本医療薬学会
- 雑誌
- 医療薬学 (ISSN:1346342X)
- 巻号頁・発行日
- vol.28, no.1, pp.57-62, 2002-02-10 (Released:2011-03-04)
- 参考文献数
- 8
- 被引用文献数
- 5 5
In 1996, the Department of Clinical Pharmacy at the Education and Research Center of Kyoto Pharmaceutical University was established to enrich the education program of pharmaceutical health care and sciences, and to also be used as a pre-training program for undergraduates before taking part in externships at hospitals or pharmacies. In the following year, the training center of clinical pharmacy (a simulated pharmacy) was also founded, and has since been used for the practical training of pharmaceutical health care and sciences for third-year undergraduate students. We herein describe our findings of an unregistered questionnaire survey of the undergraduate students' view, while also evaluating and discussing the effectiveness of this training program.Almost all students considered undergoing the practical training to be useful and necessary for them, because their scores before and after the training were 4.24 and 4.56 points on a scale of 5 point maximum, respectively. The students also evaluated each part of the training program, with mean values before and after the practice 3.75-4.01 and 3.70-4.39, respectively. The students did voice various opinions regarding the practical training program. Consequently, the students are satisfied with the practical training programs at present, however, we will have to continually improve such programs to better meet the students needs.
1 0 0 0 OA 固形がん患者における抗がん剤の適正使用のための白血球数評価
- 著者
- 根來 寛 矢野 良一 谷 大輔 渡辺 享平 塚本 仁 五十嵐 敏明 中村 敏明 脇屋 義文 後藤 伸之 横山 照由 政田 幹夫
- 出版者
- 一般社団法人日本医療薬学会
- 雑誌
- 医療薬学 (ISSN:1346342X)
- 巻号頁・発行日
- vol.34, no.4, pp.320-327, 2008 (Released:2009-09-04)
- 参考文献数
- 23
- 被引用文献数
- 2 1
During cancer chemotherapy,myelosuppression is a frequently observed toxicity manifestation which may sometimes cause severe infections.In this regard,though leukopenia-induced infections are more closely related to neutrophil counts than leukocyte counts,it is important to evaluate both leukocyte counts and neutrophil counts as markers of myelosuppression.Neutrophil counts,however,are sometimes estimated to be half leukocyte counts without conducting differential leukocyte counts.In the present study,the authors evaluated the necessity of differential leukocyte counts during cancer chemotherapy using pooled laboratory data at the University of Fukui Hospital.Variation in the percentage of neutrophils in leukocytes was observed in each leukocyte range,with the neutrophil count decreasing in pace with decreases in the leukocyte count.As an alternative index to the neutrophil count,the utility of the leukocyte count is thus considered to be low in cancer chemotherapy.There was also a divergence between adverse event grade between neutrophil and leukocyte numbers.In addition,neutrophil counts in 14.8% of the patients (26)were less than 1000/μL in spite of the fact that their leukocyte counts were higher than 3000/μL,and it was noted that 23 of them had undergone a paclitaxel-containing regimen.These results suggested that leukocyte differential counts should be measured during cancer chemotherapy,especially during the nadir period and when receiving chemotherapy containing paclitaxel.
- 著者
- 高良 恒史 大西 憲明 堀部 紗世 橋詰 勉 金澤 治男 横山 照由
- 出版者
- 日本医療薬学会
- 雑誌
- 医療薬学 (ISSN:1346342X)
- 巻号頁・発行日
- vol.29, no.1, pp.77-82, 2003
- 参考文献数
- 12
- 被引用文献数
- 5 3
For the development of a practical training system to effectively teach sterilization techniques, we conducted on unregistered questionnaire survey of the undergraduate student's view about the training practice for glass ample cutting, and then evaluated and discussed the introduction to practical training of pharmaceutical health care and sciences for the third-grade undergraduate students. Among 96 third-grade undergraduate students, 54 students (56%) had some experience in cutting glass amples while the remaining students did not. Twenty-six of the 54 students with some experience (48%) had some anxiety regarding glass ample cutting, while only 13 of the 42 inexperienced students (31%) had such anxiety. Twelve of the 13 inexperienced students overcame some anxiety against glass ample cutting. Moreover, 87 of 96 students (91%) considered that receiving practice in glass ample cutting was necessary for them. Consequently, the training programs on glass ample cutting were found to be appropriate and useful for students to develop sufficient practical skills and accurate ability in sterilization techniques. As a result, we are now preparing to introduce a training program for glass ample cutting in addition to the regular practical training of pharmaceutical health care and sciences at Kyoto Pharmaceutical University.
- 著者
- 黒田 耕司 横山 照由 梅田 常雄 喜多 良昭 小西 明 黒田 勤
- 出版者
- 公益社団法人 日本薬学会
- 雑誌
- YAKUGAKU ZASSHI (ISSN:00316903)
- 巻号頁・発行日
- vol.99, no.7, pp.745-751, 1979-07-25 (Released:2008-05-30)
- 参考文献数
- 7
- 被引用文献数
- 2 2
Physicochemical properties of the polymorphs and hydrate of 6-mercaptopurine were investigated. Its crystal habits were slightly changed and form I-TX was obtained by the addition of 6-thioxanthine and/or 2, 6-dithioxanthine and subsequent recrystallization. It was found that when Form I-TX was heated at 240°, this form transformed to Form III which was found to have a solubility about 6-7 times that of Form I. The mutual transition of 6-mercaptopurine polymorphs and hydrate under various conditions of heating and suspending in water was also studied. The transition temperature and the heat of transition between Form I-TX and Form II-TXhyd were determined to be 127°and 2.15 kcal/mol, respectively, by the solubility measurement. It was expected that if the transition of Form III could be suppressed, more bioavailable preparation of 6-mercaptopurine would be obtained.
