著者

田中 宗彦 鈴木 康策 田口 武

出版者

日本水産學會

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.49, no.7, pp.1155, 1983

著者

菅原 努 中村 実 林 太郎 深津 久治 小野 伸雄 田口 武雄

出版者

公益社団法人 日本放射線技術学会

雑誌

日本放射線技術学会雑誌 (ISSN:03694305)

巻号頁・発行日

vol.14, no.1, 1958

著者

深津 久治 小野 伸雄 佐藤 秀雄 渡辺 清 菅原 努 中村 実 田口 武雄

出版者

公益社団法人 日本放射線技術学会

雑誌

日本放射線技術学会雑誌 (ISSN:03694305)

巻号頁・発行日

vol.13, no.1, 1957

著者

菅原 努 中村 実 西田 三四郎 田口 武雄 深津 久治 小野 伸雄 高尾 義人

出版者

公益社団法人 日本放射線技術学会

雑誌

日本放射線技術学会雑誌 (ISSN:03694305)

巻号頁・発行日

vol.14, no.1, pp.81-82, 1958

著者

田中 宗彦 田口 武

出版者

公益社団法人 日本水産学会

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.51, no.7, pp.1169-1173, 1985

被引用文献数

3

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The rate of non-enzymatic browning reaction taken place during thermal processing of canned sardine was determined. Losses of glucose and G6P in the meat and liquid portions of canned sardine during thermal processing were found to follow first-order kinetics. The loss rate of G6P was greater than that of glucose. Losses of glucose and G6P in meats were larger than those in liquids. However, the activation energies for these losses were approximately 20kcal/mol for both meat and liquid portions. The available lysine degraded at a slightly slower rate, but its activation energy was also equivalent to those for glucose and G6P losses. The development of brown color in liquids of canned sardine increased with the increase in processing time by a first-order reaction (activation energy= 18.8kcal/mol). On the other hand, browning was not visually detected in the meat portion. It was found that canned sardine meats softened with the processing time at every temperature employed in this study (activation energy=35.0kcal/mol).

著者

小林 義郎 田口 武夫

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.43, no.11, pp.1073-1082, 1985-11-01 (Released:2009-11-13)

参考文献数

70

被引用文献数

12 13

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Studies on fluorine-modified vitamin D3 analogs : the design, synthesis and biological activity are reviewed. On the basis of the metabolism of vitamin D3 and the characteristic features of fluorine and fluorinated compounds, fluorine-modified vitamin D3 analogs were designed, synthesized and their biological activity was investigated to clarify the physiological significance of the metabolic hydroxylation of vitamin D3.

著者

田口 武夫

出版者

東京工業大学

巻号頁・発行日

1974

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博士論文

著者

赤羽 健司 上條 哲聖 飯塚 欣二 田口 武夫 小林 義郎 木曽 良明 梅山 秀明

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.36, no.9, pp.3447-3452, 1988-09-25 (Released:2008-03-31)

参考文献数

31

被引用文献数

3 4

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The structure-activity relationship of acyl-His-trifluorinated leucinol derivatives as inhibitors of human renal renin is discussed based upon the tertiary structure of human renin, which was deduced from the crystal structure of penicillopepsin by assuming structural similarity. The structural requirements for the inhibitors and possible interactions at the renin binding site are discussed.

著者

小林 義郎 熊懐 稜丸 田口 武夫

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.38, no.11, pp.1119-1129, 1980-11-01 (Released:2010-01-22)

参考文献数

36

被引用文献数

3 4

---

First, characteristics of a carbon-fluorine bond from the biological point of view are summarized with some examples : mimic effect, protective fluorination, irreversible conjugation with enzyme, increased lipophilicity and so on are presented. Secondly, some approaches to biologically active compounds utilizing the above characteristics are shown by the examples of trifluoromethylated nucleoside derivatives and fluorinated vitamin D3 analogues.