2 0 0 0 抗酸化物質(1)ビタミンC(アルコルビン酸)
1 0 0 0 OA 大気粉塵中化学物質の喘息患者に対する健康影響評価およびその予防法の開発
黄砂やPM2.5などの大気粉塵による健康影響が社会問題となっている。本研究では、大気粉塵中の重金属が成人慢性咳嗽(気管支喘息、咳喘息、アトピー咳)患者の目のかゆみや咳の悪化に関連していることを示した。重金属による症状の悪化は、血清IgEレベルの低い患者で強かった。重金属による影響は、アレルギー症状が弱い患者で強いことが示唆された。また、総浮遊粒子状物質とPM2.5で重金属の構成が異なっていた。特に、黄砂日では、総浮遊粒子状物質の重金属濃度は高くなったが、PM2.5では濃度があまり変わらない重金属もあった。粒子状物質による健康影響を考える上で、構成成分を考慮することが重要である。
1 0 0 0 抗酸化物質(2)ビタミンE
1 0 0 0 OA 黄砂とアレルギー疾患
- 著者
- 東 朋美 神林 康弘 藤村 政樹 大倉 徳幸 吉崎 智一 中西 清香 西條 清史 早川 和一 小林 史尚 道上 義正 人見 嘉哲 中村 裕之
- 出版者
- 日本エアロゾル学会
- 雑誌
- エアロゾル研究 (ISSN:09122834)
- 巻号頁・発行日
- vol.29, no.S1, pp.s212-s217, 2014-02-20 (Released:2014-04-01)
- 参考文献数
- 33
The frequency and scale of Asian dust events have increased rapidly in East Asia since 2000. In connection with this, the effects of Asian dust (kosa) on human health, especially on allergic diseases, are major concern in Japan. We herein discuss the effects of kosa on allergic diseases, including asthma, chronic cough and Japanese cedar pollinosis. Epidemiological studies, as well as experimental studies, have demonstrated the association between kosa and the exacerbation of asthma and allergic diseases.The kosa particles increase airway inflammation as one of the major sources of atmospheric particulate matter. Furthermore the kosa particles absorb various atmospheric gases, including air pollution. Such environmental pollution enhances the response to allergens, including Japanese cedar pollen. Recently, some epidemiological studies used the kosa data obtained by the light detection and ranging (LIDAR) system, which distinguish between mineral dust and other spherical particles, by identifying differences in the shape of the particles. Further studies using the LIDAR system will help to identify the kosa aerosol components that have adverse health effects, leading to provide new strategies to prevent environmentally induced allergic diseases.
1 0 0 0 <b>黄砂とアレルギー疾患 </b>
- 著者
- 東 朋美 神林 康弘 藤村 政樹 大倉 徳幸 吉崎 智一 中西 清香 西條 清史 早川 和一 小林 史尚 道上 義正 人見 嘉哲 中村 裕之
- 出版者
- 日本エアロゾル学会
- 雑誌
- エアロゾル研究 (ISSN:09122834)
- 巻号頁・発行日
- vol.29, no.1, pp.s212-s217, 2014
The frequency and scale of Asian dust events have increased rapidly in East Asia since 2000. In connection with this, the effects of Asian dust (<i>kosa</i>) on human health, especially on allergic diseases, are major concern in Japan. We herein discuss the effects of <i>kosa</i> on allergic diseases, including asthma, chronic cough and Japanese cedar pollinosis. Epidemiological studies, as well as experimental studies, have demonstrated the association between <i>kosa</i> and the exacerbation of asthma and allergic diseases.The <i>kosa</i> particles increase airway inflammation as one of the major sources of atmospheric particulate matter. Furthermore the <i>kosa</i> particles absorb various atmospheric gases, including air pollution. Such environmental pollution enhances the response to allergens, including Japanese cedar pollen. Recently, some epidemiological studies used the <i>kosa</i> data obtained by the light detection and ranging (LIDAR) system, which distinguish between mineral dust and other spherical particles, by identifying differences in the shape of the particles. Further studies using the LIDAR system will help to identify the <i>kosa</i> aerosol components that have adverse health effects, leading to provide new strategies to prevent environmentally induced allergic diseases.