著者
池田 博昭 高本 彩音 池田 純子 河野 清尊 中妻 章 徳村 忠一 森 久美子 飯原 なおみ 芳地 一 二宮 昌樹
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
pp.20-00136, (Released:2020-09-29)
参考文献数
23
被引用文献数
2

We investigated the success rates of eyedrop instillation and the distance between the cornea and the dropper tip in 100 volunteers using high-speed digital video recording. Past eyedrop adherence studies assumed that instillation occurred without failure. The ideal distance between the cornea and dropper tip remained unclear, although the general estimate was approximately 2.54 cm (1 inch). This study was approved by the Institutional Review Boards of all participating medical institutions, and all volunteers provided written, informed consent. Successful instillation was defined as when 1 drop fell accurately into the eye on the first attempt. The instillation of ≥2 drops or drops delivered outside the eye was considered a failure. The distance between the eye and dropper tip was measured using still images from a paused digital video camera and a digital ruler. Forty percent of the volunteers instilled eyedrops without instructions from ophthalmologists, pharmacists, or other healthcare workers. When the images were analyzed, the success rate of the first instillation was 70.1%. When the eye was arbitrarily divided into 9 sections, most of the drop sites were the iris or the center of the eye. The distance between the dropper tip and cornea was 2.62 ± 1.75 (median 2.20) cm. These results indicate that the generally recommended distance is usually followed. The successful instillation rate based on the distance from the dropper tip to the cornea was 77% at 1.6 ± 0.88 cm and 54.9% at 4.8 ± 1.25 cm.
著者
田井 達也 山口 佳津騎 黒川 直弘 新村 航 松原 亜紀 渡邊 政博 元木 貴大 田中 裕章 芳地 一 小坂 信二
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.142, no.7, pp.771-774, 2022-07-01 (Released:2022-07-01)
参考文献数
17
被引用文献数
1

We report a haemodialysis patient with end-stage renal failure whom a pharmacist aided in the management of acyclovir (ACV) encephalopathy, which may have been related to valacyclovir hydrochloride (VACV) administered without sufficient dose reduction. The patient 78 years was admitted with a tentative diagnosis of varicella zoster viral meningitis. A pharmacist suspected ACV encephalopathy related to excessive VACV administration and raised a query with the attending physician. According to the pharmacist's proposal, ACV administration was discontinued and continuous hemodiafiltration (CHDF) was performed. On day 5 of hospitalisation, the consciousness disorder was improved. In this report, we showed the detailed CHDF conditions of the present case, and the contribution of a pharmacist to treating and avoiding ACV encephalopathy was discussed.
著者
池田 博昭 高本 彩音 池田 純子 河野 清尊 中妻 章 徳村 忠一 森 久美子 飯原 なおみ 芳地 一 二宮 昌樹
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.140, no.12, pp.1455-1462, 2020-12-01 (Released:2020-12-01)
参考文献数
23
被引用文献数
2

We investigated the success rates of eyedrop instillation and the distance between the cornea and the dropper tip in 100 volunteers using high-speed digital video recording. Past eyedrop adherence studies assumed that instillation occurred without failure. The ideal distance between the cornea and dropper tip remained unclear, although the general estimate was approximately 2.54 cm (1 inch). This study was approved by the Institutional Review Boards of all participating medical institutions, and all volunteers provided written, informed consent. Successful instillation was defined as when 1 drop fell accurately into the eye on the first attempt. The instillation of ≥2 drops or drops delivered outside the eye was considered a failure. The distance between the eye and dropper tip was measured using still images from a paused digital video camera and a digital ruler. Forty percent of the volunteers instilled eyedrops without instructions from ophthalmologists, pharmacists, or other healthcare workers. When the images were analyzed, the success rate of the first instillation was 70.1%. When the eye was arbitrarily divided into 9 sections, most of the drop sites were the iris or the center of the eye. The distance between the dropper tip and cornea was 2.62±1.75 (median 2.20) cm. These results indicate that the generally recommended distance is usually followed. The successful instillation rate based on the distance from the dropper tip to the cornea was 77% at 1.6±0.88 cm and 54.9% at 4.8±1.25 cm.
著者
渡邊 政博 田井 達也 辻 繁子 田中 裕章 元木 貴大 山口 佳津騎 住吉 健太 野崎 孝徒 加地 雅人 朝倉 正登 小坂 信二 芳地 一
出版者
一般社団法人日本医薬品情報学会
雑誌
医薬品情報学 (ISSN:13451464)
巻号頁・発行日
vol.17, no.2, pp.69-76, 2015 (Released:2015-10-01)
参考文献数
22

Objective: Many patients in Kagawa University Hospital are administered medicines prepared by the simple suspension method.  Pharmacists in charge of these patients receive inquiries from doctors and nurses regarding the suitability of medicines for the simple suspension method.  Answering these inquiries is complicated and time-consuming as multiple data sources need to be searched.  In order to simplify these complicated procedures, we herein attempted to develop a novel database to provide valuable information that could contribute to the safe performance of the simple suspension method, and evaluated its usefulness.Method: The specifications of the database were determined by analyzing previously answered inquiries.  To evaluate the usefulness of the database, we used test prescriptions and compared the amount of time required to gather information using the database and the conventional method, i.e., using books alone.  We also analyzed previous prescriptions with the database in order to determine what kinds of problems could be detected.Results: The investigation of previous prescriptions indicated that some medicines needed to be examined not only for their suitability for the simple suspension method, but also their incompatibility.  Therefore, we added a feature regarding the incompatibility of medicines to the database.  The time required to gather the information needed to answer the test prescription was shorter with our database than with the conventional method.  Furthermore, the database improved the detection of medicines that require particular attention for their properties including incompatibility.  An analysis of previous prescriptions using our database indicated the possibility of incompatibility in half of the previous prescriptions examined.Conclusion: Our database could rapidly provide information related to the simple suspension method, including the incompatibility of medicines.
著者
池田 博昭 中妻 章 森 久美子 飯原 なおみ 芳地 一 二宮 昌樹 夛田羅 勝義
雑誌
日本薬学会第141年会(広島)
巻号頁・発行日
2021-02-01

【目的】2020年度授業は4月6日より対面授業を開始予定だったが、2週間遅れて4月20日から遠隔授配信授業を開始した。2ヶ月後の6月16日より対面授業を開始したため、学生は遠隔授配信授業と対面授業の2つの授業形態を経験した。学生に遠隔配信授業と対面授業のアンケートを実施し課題を抽出した。【方法】6年生と4年生に同じ質問内容のアンケートを実施した。内容は遠隔配信授業と対面授業のどちらが便利か、好むかなど13項目とした。6年生は筆記式、4年生は遠隔授配信授業で回答した。アンケートは無記名、成績評価に影響しない、結果を学会等で公表する同意を口頭で得た。【結果】6年生の56名中37名(66.1%, 男19名、女18名)が回答した。遠隔配信授業へのストレスは9名(24.1%)が感じ、その内容は通信量不足のためか遠隔配信の通知が遅れるなどWifi環境が原因だった(66.7%)。遠隔配信授業を有効としたのは29名(78.4%)、どちらでもない8名(21.6%)だった。遠隔配信授業に向いた授業は演習科目28名(75.7%)、スライド説明中心科目26名(70.3%)だった。遠隔配信講義の長所は通学時間がない28名(75.7%)、授業データ保存7名(18.9%)、卒業研究の実験しながら2名(5.4%)だった。37名中35名(94.6%)は遠隔配信授業が便利と回答、37名中21名(56.8%)は遠隔配信授業が好きと回答、16名(43.2%)は対面授業が好きと回答した。4年生32名中32名(男9名、女23名)が回答(100%)した。32名中30名(93.9%)は遠隔配信授業が便利と回答、32名中23名(71.9%)は遠隔配信授業が好きと回答、9名(28.1%)は対面授業が好きと回答した。【考察】学生は通学時間が不要などの理由で遠隔配信授業が便利と考える一方、遠隔配信授業は授業科目によると回答した。遠隔配信授業が好きと対面授業が便利に有意差はなく、授業科目に配慮して行えば通信量不足に悩む学生の満足は得られる。