著者
池田 博昭 高本 彩音 池田 純子 河野 清尊 中妻 章 徳村 忠一 森 久美子 飯原 なおみ 芳地 一 二宮 昌樹
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
pp.20-00136, (Released:2020-09-29)
参考文献数
23
被引用文献数
2

We investigated the success rates of eyedrop instillation and the distance between the cornea and the dropper tip in 100 volunteers using high-speed digital video recording. Past eyedrop adherence studies assumed that instillation occurred without failure. The ideal distance between the cornea and dropper tip remained unclear, although the general estimate was approximately 2.54 cm (1 inch). This study was approved by the Institutional Review Boards of all participating medical institutions, and all volunteers provided written, informed consent. Successful instillation was defined as when 1 drop fell accurately into the eye on the first attempt. The instillation of ≥2 drops or drops delivered outside the eye was considered a failure. The distance between the eye and dropper tip was measured using still images from a paused digital video camera and a digital ruler. Forty percent of the volunteers instilled eyedrops without instructions from ophthalmologists, pharmacists, or other healthcare workers. When the images were analyzed, the success rate of the first instillation was 70.1%. When the eye was arbitrarily divided into 9 sections, most of the drop sites were the iris or the center of the eye. The distance between the dropper tip and cornea was 2.62 ± 1.75 (median 2.20) cm. These results indicate that the generally recommended distance is usually followed. The successful instillation rate based on the distance from the dropper tip to the cornea was 77% at 1.6 ± 0.88 cm and 54.9% at 4.8 ± 1.25 cm.
著者
馬場 香菜子 小原 依里 飯原 なおみ
出版者
一般社団法人 日本医薬品情報学会
雑誌
医薬品情報学 (ISSN:13451464)
巻号頁・発行日
vol.22, no.1, pp.35-43, 2020-05-29 (Released:2020-06-13)
参考文献数
29

Benzodiazepine receptor agonists (BZs) are medications to be used with caution, not only for long-time users, but also for first-time users. This study aimed to compare the use of BZs or central nervous system (CNS) agents in first-time BZs users (FU) and continuing BZs users (CU). Using a large health insurance claims database in Japan, BZs users aged ≥40 years in 2013 who were opioid non-users without hospitalization were classified into FU or CU, by use of BZs in the first half-year. BZs or CNS agent use at the index date (the first date BZs were dispensed in the latter year) was investigated as follows: (1) proportion of patients with prescriptions of BZs for use as needed (BZs-AN), (2) daily number of BZs or CNS agents, and (3) daily standardized dose of BZs or CNS agents. More individuals in the FU group (3,162/16,576; 19%) than in the CU group (7,627/46,088; 17%) received BZs-AN (p<0.001); 87% of the FU group vs 62% of the CU group used single BZs (p<0.001), and 53% vs 24% used less than 5 mg/day of equivalent diazepam (p<0.001). A similar trend was found for CNS agents. Numbers or doses of BZs or CNS agents decreased with increasing age in both groups. However, some first-time users aged 70-74years started with ≥2 types of BZs or ≥10 mg/day of equivalent diazepam. Overall, BZs for outpatients without opioids were started carefully, but a prescription review was necessary for some patients, requiring more effort from healthcare providers.
著者
飯原 なおみ 吉田 知司 岡田 岳人 中妻 章 桐野 豊
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.40, no.2, pp.67-77, 2014-02-10 (Released:2015-02-10)
参考文献数
12
被引用文献数
2 5

There is no report to date regarding the usage status of medications with driving with prohibitions or cautions in Japan. Upon sampling the national health insurance claims database (covering 1% of outpatients), we surveyed the prescriptions and use of medications in outpatient settings for patients aged 25 years and older, with the goal of encouraging the proper use of medications.We analyzed the ratio of outpatients who were administered medications with prohibitions or cautions on driving to total outpatients who were administered medications (prescribed and/or provided to them at the time of examination). We also examined daily dosages and deviations from specified dose-limits for their prescribed oral medications.Of 566,968 outpatients aged 25 years and older who were administered medications, 413,940 (73%) outpatients were given the medications with cautions or prohibitions on driving and 243,405 (43%) outpatients were administered the medications with a prohibition on driving.Daily dosages of many medications were reduced with the increase in age of the patient. The degree of dosage reduction varied widely, with some medications whose dosages were hardly adjusted with age. With some medications with dose-limitations or contraindications for the elderly, prescriptions were found with dosages that often exceeded the recommended limits.We conclude that outpatients given medications and/or prescriptions must exercise appropriate caution when driving and that the dosage of these medications should be adjusted especially in the elderly.
著者
池田 博昭 高本 彩音 池田 純子 河野 清尊 中妻 章 徳村 忠一 森 久美子 飯原 なおみ 芳地 一 二宮 昌樹
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.140, no.12, pp.1455-1462, 2020-12-01 (Released:2020-12-01)
参考文献数
23
被引用文献数
2

We investigated the success rates of eyedrop instillation and the distance between the cornea and the dropper tip in 100 volunteers using high-speed digital video recording. Past eyedrop adherence studies assumed that instillation occurred without failure. The ideal distance between the cornea and dropper tip remained unclear, although the general estimate was approximately 2.54 cm (1 inch). This study was approved by the Institutional Review Boards of all participating medical institutions, and all volunteers provided written, informed consent. Successful instillation was defined as when 1 drop fell accurately into the eye on the first attempt. The instillation of ≥2 drops or drops delivered outside the eye was considered a failure. The distance between the eye and dropper tip was measured using still images from a paused digital video camera and a digital ruler. Forty percent of the volunteers instilled eyedrops without instructions from ophthalmologists, pharmacists, or other healthcare workers. When the images were analyzed, the success rate of the first instillation was 70.1%. When the eye was arbitrarily divided into 9 sections, most of the drop sites were the iris or the center of the eye. The distance between the dropper tip and cornea was 2.62±1.75 (median 2.20) cm. These results indicate that the generally recommended distance is usually followed. The successful instillation rate based on the distance from the dropper tip to the cornea was 77% at 1.6±0.88 cm and 54.9% at 4.8±1.25 cm.
著者
浦上 勇也 木村 功二 河田 由紀子 枯木 始 須﨑 晶子 河﨑 光彦 山本 和幸 飯原 なおみ
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.43, no.6, pp.344-350, 2017-06-10 (Released:2018-06-10)
参考文献数
12
被引用文献数
3 4

Pharmacists are expected to help reduce increasing healthcare costs. This study assessed the effects of pharmacists at community pharmacies checking for unused prescribed medications using a bag in which patients put medications (Setsuyaku Bag). We examined whether this check improved medication adherence and also measured the costs of the unused medications.Patients aged ≥ 20 years who brought the bag to community pharmacies were followed-up for 6 months. They took the bag to pharmacies if they had unused medications including those recently prescribed. Medication adherence scores at the first visit and after 6 months were assessed by patients (good 0–bad 4) and by pharmacists (good 1–bad 4). Changes in scores were analyzed using paired t-tests. Costs of unused medications were calculated, grouped as reused, saved, or discarded.The patient adherence score for 73 patients (mean age 71.3 years) decreased from a mean of 1.8, SE 0.1 at the first visit to 0.8, 0.1 at the 6-month visit (P < 0.001). The pharmacist adherence score also decreased over this period from a mean of 2.4, SE 0.1 to 1.5, 0.8 (P < 0.001). The mean cost of total unused medications during the 6-month per person was 9,962 yen: reused 6,523 yen (65.5%), saved 1,506 yen (15.1%), and discarded 1,933 yen (19.4%).Pharmacists' checkup for unused medications using a Setsuyaku Bag was likely to be effective for improving medication adherence, indicating that pharmacists can contribute indirectly to reducing healthcare costs through medication adherence and directly by lowering medication costs.
著者
河添 仁 飯原 なおみ 土居 智明 森田 修之
出版者
公益社団法人日本薬学会
雑誌
藥學雜誌 (ISSN:00316903)
巻号頁・発行日
vol.125, no.12, pp.959-969, 2005-12-01
被引用文献数
2

The proclamation of April 2002 of a Ministry of Health, Labor and Welfare ordinance has enabled doctors to prescribe drugs for an outpatient without a limit on the length of prescription terms except for a few drugs. There is a concern that the prescription-term deregulation could cause careless drug therapy management in order to extend the interval between patient hospital visits. The purpose of this study is to make pre- and post-deregulation comparisons of two items, prescription terms and implementation of clinical examination that complied with package-insert precautions, and to discuss the approaches to increase safety. Prescription terms have lengthened progressively. In the preregulation period of January to March 2002, the mean prescription term was 19.9 days; in the post-regulation period of July to September 2002, it was 24.9 days; and in July to September 2003, 28.6 days. Even for anti-tumor agents, there were prescriptions over 90 days after deregulation. There was no significant difference between the pre- and post-deregulation compliance ratios for the package-insert precautions in eight drugs of investigated nine. However, one case had a delay in detection of liver dysfunction, which was caused by deviation from the once-a-month testing indicated in the package-insert precautions for prolonged prescription terms. The evidence suggested that the deregulation led to negligent drug therapy management. To assure safe therapy, the following should be addressed : first, sufficient function of a computerized prescriber order entry system and second, creation of a new framework with pharmacists' active involvement such as collaborative therapy management with physicians.
著者
池田 博昭 中妻 章 森 久美子 飯原 なおみ 芳地 一 二宮 昌樹 夛田羅 勝義
雑誌
日本薬学会第141年会(広島)
巻号頁・発行日
2021-02-01

【目的】2020年度授業は4月6日より対面授業を開始予定だったが、2週間遅れて4月20日から遠隔授配信授業を開始した。2ヶ月後の6月16日より対面授業を開始したため、学生は遠隔授配信授業と対面授業の2つの授業形態を経験した。学生に遠隔配信授業と対面授業のアンケートを実施し課題を抽出した。【方法】6年生と4年生に同じ質問内容のアンケートを実施した。内容は遠隔配信授業と対面授業のどちらが便利か、好むかなど13項目とした。6年生は筆記式、4年生は遠隔授配信授業で回答した。アンケートは無記名、成績評価に影響しない、結果を学会等で公表する同意を口頭で得た。【結果】6年生の56名中37名(66.1%, 男19名、女18名)が回答した。遠隔配信授業へのストレスは9名(24.1%)が感じ、その内容は通信量不足のためか遠隔配信の通知が遅れるなどWifi環境が原因だった(66.7%)。遠隔配信授業を有効としたのは29名(78.4%)、どちらでもない8名(21.6%)だった。遠隔配信授業に向いた授業は演習科目28名(75.7%)、スライド説明中心科目26名(70.3%)だった。遠隔配信講義の長所は通学時間がない28名(75.7%)、授業データ保存7名(18.9%)、卒業研究の実験しながら2名(5.4%)だった。37名中35名(94.6%)は遠隔配信授業が便利と回答、37名中21名(56.8%)は遠隔配信授業が好きと回答、16名(43.2%)は対面授業が好きと回答した。4年生32名中32名(男9名、女23名)が回答(100%)した。32名中30名(93.9%)は遠隔配信授業が便利と回答、32名中23名(71.9%)は遠隔配信授業が好きと回答、9名(28.1%)は対面授業が好きと回答した。【考察】学生は通学時間が不要などの理由で遠隔配信授業が便利と考える一方、遠隔配信授業は授業科目によると回答した。遠隔配信授業が好きと対面授業が便利に有意差はなく、授業科目に配慮して行えば通信量不足に悩む学生の満足は得られる。
著者
浦上 勇也 山地 康文 篠永 浩 河田 由紀子 久家 哲也 山本 和幸 飯原 なおみ
出版者
一般社団法人 日本呼吸ケア・リハビリテーション学会
雑誌
日本呼吸ケア・リハビリテーション学会誌 (ISSN:18817319)
巻号頁・発行日
vol.29, no.1, pp.117-124, 2020-08-31 (Released:2020-09-02)
参考文献数
19

【背景】保険薬局において喘息患者に対する吸入指導を医師と連携して行うことは難しい.【目的】吸入指導連絡票を用いた,医療機関と連携した保険薬局における吸入実技指導が,臨床効果に与える影響を検討した.【方法】医療機関から吸入指導連絡票が発行された喘息患者に対し,薬剤師が吸入実技指導を実施した.吸入アドヒアランス,理解度・吸入手技,臨床効果指標(ACT,%PEF)を指標とし,指導1,2,3回目に測定して,その変化を全患者および年齢層別に解析した.【結果】解析対象31名において,全ての指標値は1回目に比べ2,3回目で有意に改善した.年齢層別では,60歳未満群では一部改善しない指標値があったが60歳以上群では全ての指標値が有意に改善した.【考察】吸入指導連絡票を用いた保険薬局における吸入実技指導は,医師と薬剤師の双方向の情報連携を可能とし,喘息コントロールを維持する上で有効である.
著者
浦上 勇也 髙島 秀人 篠永 浩 矢野 禎浩 飯原 なおみ
出版者
日本社会薬学会
雑誌
社会薬学 (ISSN:09110585)
巻号頁・発行日
vol.39, no.2, pp.58-62, 2020-12-10 (Released:2020-12-30)
参考文献数
10

Objectives: Collaboration among medical, nursing, and welfare staff members in a community is needed to promote community-based integrated care in Japan; however, these individuals have few opportunities to communicate. We held a Care Cafe®, which establishes face-to-face relationships among the staff members in a community, evaluated changes in the extent of community collaboration over time, and tracked the number of times each individual participated. Methods: Participants in the Care Cafe® were asked to complete a questionnaire measuring the extent of community collaboration among medical, nursing, and welfare staff members at the time of first participation and approximately one to two years later. Responses were evaluated with a 5-point rating scale to reveal the extent of collaboration (total score and six subscale scores), how the participants felt about the collaboration, and the number of staff members in the community who could support them. Results: Thirty-six participants responded, including 12 community pharmacists, 10 care managers, 5 physical therapists, 3 hospital pharmacists, and 6 others. Of them, 22 (61.1%) participated at least three times. The total score and the five subscale scores, the proportion of participants who rated their collaboration as good, and the reported number of staff members who could support them increased significantly from the time of first participation. Thirteen participants (36.1%), each of whom participated at least three times, responded that their participation resulted in practical collaboration. Conclusions: The Care Cafe® can improve collaboration among medical, nursing, and welfare staff members in a community. More frequent participation may promote collaboration.
著者
飯原 なおみ 吉田 知司 岡田 岳人 中妻 章 桐野 豊
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.40, no.2, pp.67-77, 2014
被引用文献数
5

There is no report to date regarding the usage status of medications with driving with prohibitions or cautions in Japan. Upon sampling the national health insurance claims database (covering 1% of outpatients), we surveyed the prescriptions and use of medications in outpatient settings for patients aged 25 years and older, with the goal of encouraging the proper use of medications.We analyzed the ratio of outpatients who were administered medications with prohibitions or cautions on driving to total outpatients who were administered medications (prescribed and/or provided to them at the time of examination). We also examined daily dosages and deviations from specified dose-limits for their prescribed oral medications.Of 566,968 outpatients aged 25 years and older who were administered medications, 413,940 (73%) outpatients were given the medications with cautions or prohibitions on driving and 243,405 (43%) outpatients were administered the medications with a prohibition on driving.Daily dosages of many medications were reduced with the increase in age of the patient. The degree of dosage reduction varied widely, with some medications whose dosages were hardly adjusted with age. With some medications with dose-limitations or contraindications for the elderly, prescriptions were found with dosages that often exceeded the recommended limits.We conclude that outpatients given medications and/or prescriptions must exercise appropriate caution when driving and that the dosage of these medications should be adjusted especially in the elderly.