著者

野中 源一郎 松本 陽子 西岡 五夫

出版者

公益社団法人日本薬学会

雑誌

Chemical & pharmaceutical bulletin (ISSN:00092363)

巻号頁・発行日

vol.29, no.4, pp.1184-1187, 1981-04-25

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A novel hydrolyzable tannin named trapain has been isolated from Trapa japonica FLEROV. (Oenotheraceae), and the structure has been established as II on the basis of the spectroscopic and chemical evidences.

著者

野中 源一郎 原田 美沙子 西岡 五夫

出版者

公益社団法人日本薬学会

雑誌

Chemical & pharmaceutical bulletin (ISSN:00092363)

巻号頁・発行日

vol.28, no.2, pp.685-687, 1980-02-25

被引用文献数

2

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A new ellagitannin, eugeniin was isolated from cloves, the dried flower buds of Eugenia caryophyllata THUNB., and the structure was determined to be 1,2,3-trigalloyl 4,6-hexahydroxydiphenoyl β-D-glucopyranose.

著者

西岡 五夫

出版者

公益社団法人 日本薬学会

雑誌

ファルマシア (ISSN:00148601)

巻号頁・発行日

vol.11, no.5, pp.327-330, 1975-05-01 (Released:2018-08-26)

著者

西岡 五夫

出版者

The Japan Society for Oriental Medicine

雑誌

日本東洋医学雑誌 (ISSN:02874857)

巻号頁・発行日

vol.46, no.5, pp.631-644, 1996-03-20 (Released:2010-03-12)

参考文献数

9

被引用文献数

1 1

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大黄の向精神作用について, 化学的, 行動薬理学的及び神経化学的検討を行い, 下記の結論を得た。1. 大黄の向精神作用成分は, RG-タレニンである。2. 大黄の向精神作用は, 典型抗精神病薬の作用によく一致するが, 行動毒性を伴わない特長がある。これは, カタレプシーなどを惹起しないこと, また脳内ドパミン神経系の黒質―線条体路に対する影響が少ないことから立証された。

著者

柏田 良樹 森田 益史 野中 源一郎 西岡 五夫

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.38, no.4, pp.856-860, 1990-04-25 (Released:2008-03-31)

参考文献数

13

被引用文献数

11 15

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A chemical examination of the polyphenolic constituents of the fern, Dicranopteris pedata HOUTT., has led to the isolation of eight new proanthocyanidins possessing a doubly-linked (A-type) unit, together with known flavan-3-ols and proanthocyanidins. On the basis of chemical and spectroscopic evidence, they are characterized as epiafzelechin-(4β→8, 2β→O→7)-eniafzelechin-(4α→8)-epiafzelechin(8), epicatechin-(4β→8, 2β→O→7)-epiafzelechin-(4α→8)-epiafzelechin(9), epiafzelechin-(4β→8, 2β→O→7)-epizfzelechin-(4α→8)-epicatechin(10), epiafzelechin-(4β→8, 2β→O→7)-epicatechin-(4α→8)-epicatechin (11), epicatechin-(4β→8, 2β→O→7)-epiafzelechin-(4α→8)-epicatechin (12), epicatechin-(4β→8, 2β→O→7)-epicatechin-(4α→8)-epiafzelechin (13), epicatechin-(4β→8, 2β→O→7)-epicatechin-(4α→8)-epigallocatechin (14) and epiafzelechin-(4β→8)epicatechin-(4β→8, 2β→O→β→7)-epicatechin-(4α→8)-epicatechin (15).

著者

塚本 赳夫 西岡 五夫 木下 洋夫

出版者

公益社団法人 日本薬学会

雑誌

藥學雜誌 (ISSN:00316903)

巻号頁・発行日

vol.75, no.8, pp.1019-1020, 1955

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Following the extraction of a sterol as the non-saponifiable matter from the ether extract of the root of <i>Oenothera lamarckiana</i> Ser., which was assumed to be &beta;-sitosterol, the presence of sterol was examined in four kinds of Oenothera spp., <i>O. odorata</i> Jacp., <i>O. parviflora</i> L., <i>O. lacimata</i> Hill., and <i>O. tetraptera</i> Cav. These plants all yielded the same sterol as that obtained from <i>O. lamarckiana</i> Ser.

著者

世取山 守 伊藤 功 高島 大典 正山 征洋 西岡 五夫

出版者

公益社団法人日本薬学会

雑誌

藥學雜誌 (ISSN:00316903)

巻号頁・発行日

vol.100, no.6, pp.611-614, 1980-06-25

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Cannabinoids (CN) of CBDA stock, Tochishi No. 1 stock and crossed stock were determined on a high-pressure liquid chromatograph equipped with a LiChrosorb RP-18 column (25 cm×4 mm) by elution with a mixture of methanol and 0.02 N sulphuric acid (4 : 1). The CBDA stock was found to contain cannabidiolic acid (CBDA) and cannabichromenic acid (CBCA). Tochishi No. 1 stock was detected to have thtrahydrocannabinolic acid (THCA), CBCA and a small amount of CBDA. F_1 was obtained by crossing CBDA stock (female) and Tochishi No. 1 stock (male). All 79 F_1 specimens were found to contain CBDA, THCA and CBCA. Therefore F_1 was designated the median type. F_2 was then obtained by crossing F_1 and out of 199 F_2 specimens, 58,40 and 101 stocks were designated as CBDA stock type, Tochishi No. 1 stock type and the median type by CN analysis, respectively. F_3 was also gained by crossing CBDA stock type of F_2 and all 166 F_3 specimens were CBDA stock type. F_4,which was obtained by crossing F_3,was also CBDA stock type. In addition, the fibers of F_4 were found to be better than those of the original CBDA stock, and F_4 contained a negligible amount of THCA.

著者

西岡 五夫 松尾 律子 大倉 洋甫 百瀬 勉

出版者

公益社団法人日本薬学会

雑誌

薬学雑誌 (ISSN:00316903)

巻号頁・発行日

vol.88, no.10, pp.1281-1285, 1968-10

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A new colorimetric method for microdetermination of isothiocyanates was established, using 3,6-dinitrophthalic acid as a color developing agent in a potassium carbonatesodium thiosulfate solution. The reaction conditions were examined with allyl isothiocyanate as a model compound. The outline of the procedure is as follows : To 2.0 ml of allyl isothiocyanate solution (10-150 μg/ml), (dissolved in 50% ethylene glycol solution, 1.0 ml of 3,6-dinitrophthalic acid monopyridinium salt solution (0.1%), and 1.0 ml of alkaline solution (40% potassium carbonate and 30% sodium thiosulfate) are added and mixed well. The mixture is heated in a boiling water bath for exactly 10 minutes, cooled in running water, and diluted to 20.0 ml with water. The absorbance of the developed color is read at 400 mμ against the reagent blank. In this color reaction, 3,6-dinitrophthalic acid was assumed to be reduced to 3-amino-6-nitrophthalic acid by S^<2->, which was liberated from allyl isothiocyanate in the alkaline medium.