著者
河合 光久 瀬戸山 裕美 高田 敏彦 清水 健介 佐藤 美紀子 眞鍋 勝行 牧野 孝 渡邉 治 吉岡 真樹 野中 千秋 久代 明 池邨 治夫
出版者
公益財団法人 腸内細菌学会
雑誌
腸内細菌学雑誌 (ISSN:13430882)
巻号頁・発行日
vol.25, no.3, pp.181-187, 2011 (Released:2011-09-06)
参考文献数
16
被引用文献数
2

便秘傾向で60歳以上の健常成人男女58名(平均年齢68.8±5.3歳)に,Bifidobacterium breveヤクルト株が製品1個あたり1.0×1010 cfu含まれるはっ酵乳(商品名 ミルミル)を連続4週間摂取するオープン試験を実施した.被験者は排便日数が週に3から5日で,便の硬めな(便の水分含量が70%未満)人を選択した.はっ酵乳(試験食品)の4週間摂取は,排便量の増加を伴った排便回数および排便日数の有意な増加を示した(各々p<0.0001).さらに3日間以上連続で排便のなかった被験者の割合も試験食品摂取により低下した(p=0.013).しかし,便の硬さを表す便性状スコア(Bristol stool scale)の評価では,試験食品の摂取によって平均スコアに変化は認められなかった.症状の程度を5段階で評価した排便時の症状および腹部症状スコアに対し,試験食品はいきみおよび残便感の平均スコアを低下し(各々p=0.022および0.0002),症状の軽減が示唆されたが,腹痛および腹部膨満感のスコアには顕著な変化はみられなかった.色素を経口摂取してから便中に色素が検出されるまでの時間(腸管通過時間)を観察したところ,色素の滞留時間は摂取前後で変化はみられなかった.以上の結果より,連続4週間のB.breveヤクルト株を含むビフィズス菌はっ酵乳の摂取は,便秘傾向な60歳以上の健常な男女において排便量の増加を促し,排便頻度の増加および排便リズムを安定化させる便秘改善効果が示唆された.また,排便時のいきみや残便感の症状を改善する可能性も示唆された.
著者
庄司 吏香 三ツ口 千代菊 早瀬 須美子 熊谷 佳子 徳留 裕子 山中 克己 早川 弘子 淡路 比呂代 野中 千秋 河合 光久 藤木 理代
出版者
日本食生活学会
雑誌
日本食生活学会誌 (ISSN:13469770)
巻号頁・発行日
vol.27, no.4, pp.249-257, 2017 (Released:2017-04-27)
参考文献数
43
被引用文献数
1 1

This study aimed to clarify the influence of dietary habits and the daily intake of fermented milk product containing Bifidobacterium breve strain Yakult, 1.0 × 1010 cfu/100 mL/day on bowel habits in healthy young Japanese women. To clarify the interaction of a fermented milk product containing Bifidobacterium breve strain Yakult, 1.0 × 1010 cfu/100 mL/day, and food intake on bowel habits in healthy young Japanese women. A total of 150 female university students participated in this study. They recorded the amount of food intake using a food-frequency questionnaire (FFQ) during the pre-experiment period and bowel habits in a diary during the study. After the exclusion of 30 subjects who defecated every day, 120 subjects were randomly divided two groups.Pre experiment they recorded the amount of food intake using food-frequency questionnaire (FFQ) and bowel habits. After excluded 30 subjects who defecated every day, we divided two groups. We conducted an open cross-over ,study, which was composed of a non-intake period (4 weeks), a washout period (2 weeks), and an intake period (4 weeks). Sixty-two subjects, who completed the study and fully recorded in a diary, were included in the analysis. We conducted an open cross-over study. The study period was 10 weeks including a non-intake period, washout period, and an intake period. During the intake period the defecation frequency was increased from 72.2 ± 18.6 to 77.7 ± 18.8% (p < 0.01). The Bristol Stool Scale was increased from 3.2 ± 0.8 to 3.4 ± 0.9(p < 0.01). As assessed by a 5-point Likert scale, the average scores of straining and feeling of incomplete evacuation was decreased from 2.0 ± 0.8 to 1.7 ± 0.7 (p < 0.01). As assessed by a visual analog 10-point scale, the average scores of constipation awareness was decreased from 4.1 ± 2.0 to 3.3 ± 1.9 (p < 0.01). In contrast, tThe amount of calorie intake was remarkably smaller than that in recommended value (1532 ± 314 v.s.1950 kcal). Especially the consumption of potato, beans, vegetable, and fruits were smaller than recommended value. The defecation frequency during the intake period was positively correlated with each amount of calorie intake and carbohydrate intake(each p < 0.05)but not with the amount of dietary fiber intake. These findings suggest that a daily intake of fermented milk containing Bifidobacterium and an adequate food intake might provide benefits improving the bowel habit in healthy young Japanese women.