著者

山口 覚 Satoshi Yamaguchi

雑誌

人文論究 = Jimbun ronkyu : humanities review (ISSN:02866773)

巻号頁・発行日

vol.67, no.4, pp.1-26, 2018-02-10

著者

山口 覚 喜多 祐子 Satoshi Yamaguchi Yuko Kita

雑誌

関西学院大学先端社会研究所紀要 = Annual review of the institute for advanced social research (ISSN:18837042)

巻号頁・発行日

no.11, pp.11-26, 2014-03-31

著者

山口 覚 Satoshi Yamaguchi

出版者

関西学院大学人文学会

雑誌

人文論究 (ISSN:02866773)

巻号頁・発行日

vol.67, no.4, pp.1-26, 2018-02

著者

山口 覚 Satoshi Yamaguchi

雑誌

人文論究 = Jimbun ronkyu : humanities review (ISSN:02866773)

巻号頁・発行日

vol.71, no.4, pp.37-61, 2022-02-10

著者

山口 覚 Satoshi Yamaguchi

出版者

関西学院大学史学会

雑誌

関西学院史学 (ISSN:04511263)

巻号頁・発行日

no.41, pp.1-27, 2014-03

著者

山口 覚 Satoshi Yamaguchi

雑誌

人文論究 = Jimbun ronkyu : humanities review (ISSN:02866773)

巻号頁・発行日

vol.71, no.4, pp.37-61, 2022-02-10

著者

Takahiko Sakai Hefei Li Tatsuki Shimada Suzune Kita Maho Iida Chunwoo Lee Tamaki Nakano Satoshi Yamaguchi Satoshi Imazato

出版者

Japan Prosthodontic Society

雑誌

Journal of Prosthodontic Research (ISSN:18831958)

巻号頁・発行日

pp.JPR_D_22_00053, (Released:2022-08-25)

参考文献数

38

被引用文献数

12

---

Purpose: This study aimed to develop an artificial intelligence (AI) model to support the determination of an appropriate implant drilling protocol using cone-beam computed tomography (CBCT) images.Methods: Anonymized CBCT images were obtained from 60 patients. For each case, after implant placement, images of the bone regions at the implant site were extracted from 20 slices of CBCT images. Based on the actual drilling protocol, the images were classified into three categories: protocols A, B, and C. A total of 1,200 images were divided into training and validation datasets (n = 960, 80%) and a test dataset (n = 240, 20%). Another 240 images (80 images for each type) were extracted from the 60 cases as test data. An AI model based on LeNet-5 was developed using these data sets. The accuracy, sensitivity, precision, F-value, area under the curve (AUC) value, and receiver operating curve were calculated.Results: The accuracy of the trained model is 93.8%. The sensitivity results for drilling protocols A, B, and C were 97.5%, 95.0%, and 85.0%, respectively, while those for protocols A, B, and C were 86.7%, 92.7%, and 100%, respectively, and the F values for protocols A, B, and C were 91.8%, 93.8%, and 91.9%, respectively. The AUC values for protocols A, B, and C are 98.6%, 98.6%, and 99.4%, respectively.Conclusion: The AI model established in this study was effective in predicting drilling protocols from CBCT images before surgery, suggesting the possibility of developing a decision-making support system to promote primary stability.

著者

Satoshi Yamaguchi

出版者

Japan Prosthodontic Society

雑誌

Journal of Prosthodontic Research (ISSN:18831958)

巻号頁・発行日

vol.67, no.1, pp.viii-ix, 2023 (Released:2023-01-06)

参考文献数

10

著者

Kotaro Sato Koki Fujii Noriyuki Yamamoto Norihisa Ichimura Satoshi Yamaguchi Hirohisa Yamada Hideharu Hibi Shinya Toyokuni

出版者

SOCIETY FOR FREE RADICAL RESEARCH JAPAN

雑誌

Journal of Clinical Biochemistry and Nutrition (ISSN:09120009)

巻号頁・発行日

vol.71, no.2, pp.129-135, 2022 (Released:2022-09-01)

参考文献数

22

被引用文献数

2

---

COVID-19 is pandemic since 2020 and further information is necessary on the risk factors associated with the infection of SARS-CoV-2. As an entry mechanism, SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) as receptor and transmembrane serine protease 2 (TMPRSS2) to activate fusion with host plasma membrane. Because dysgeusia is an early symptom of COVID-19, we here studied the expression of ACE2 and TMPRSS2 in the tongue and the associated tissues of mice and humans with immunohistochemistry and immunoblot analysis. ACE2 expression was low in the human tongue but was observed in the squamous epithelium, perineurium, arterial wall, salivary glands as well as taste buds. In contrast, mice showed high expression. In sharp contrast, TMPRSS2 expression was high in all the cells mentioned above in humans but relatively low in mice except for salivary glands. We then performed semi-quantitation of immunohistochemistry data of human ACE2 and TMPRSS2 and analyzed for age, sex, alcohol intake, and smoking habit with logistic regression analysis. We found that alcohol intake and female gender were the significant risk factors for increasing TMPRSS2 expression. In conclusion, TMPRSS2 is an important factor to be considered regarding SARS-CoV-2 entry and amplification in the oral cavity, which is promoted through drinking habit.

著者

山口 覚 Satoshi Yamaguchi

雑誌

人文地理 (ISSN:00187216)

巻号頁・発行日

vol.48, no.2, pp.182(76)-196(90), 1996

著者

Satoshi Yamaguchi Masami Abe Kunitoshi Iseki Tomohiro Arakaki Osamu Arasaki Michio Shimabukuro Shinichiro Ueda

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

pp.CR-20-0058, (Released:2020-07-18)

参考文献数

20

被引用文献数

2

---

Background:Serum electrolyte concentrations on admission and after the administration of loop diuretics may be associated with prognosis in patients hospitalized due to acute heart failure (AHF). This study investigated the prognostic impact of early changes in chloride (Cl) concentrations after diuretic administration, according to stratified Cl concentrations on admission, in AHF.Methods and Results:In all, 355 consecutive patients hospitalized due to AHF were included in this single-center retrospective cohort study. Patients were divided into 2 groups based on whether Cl decreased (n=196) or not (n=159) during the first 5 days in hospital. These 2 groups were further stratified according to Cl on admission into 4 groups: Group 1, decrease in Cl and no hypochloremia (n=127); Group 2, decrease in Cl and hypochloremia (n=69); Group 3, no decrease in Cl and no hypochloremia (n=50); and Group 4, no decrease in Cl and hypochloremia (n=109). The risk of death was significantly higher in the group without than with a decrease in Cl (all-cause death hazard ratio [HR] 1.79; 95% confidence interval [CI] 1.15–2.78; P=0.009). Group 4 had the worst prognosis and a significantly higher risk of death (all-cause death [vs. Group 1 as a reference], HR 2.51; 95% CI 1.45–4.32; P=0.001).Conclusions:The absence of an early decline in Cl was associated with poor prognosis in AHF, especially in patients with hypochloremia on admission.

著者

山口 覚 Satoshi Yamaguchi

出版者

関西学院大学人文学会

雑誌

人文論究 (ISSN:02866773)

巻号頁・発行日

vol.63, no.1, pp.101-128, 2013-05

著者

山口 覚 Satoshi Yamaguchi

雑誌

関西学院大学先端社会研究所紀要 = Annual review of the institute for advanced social research (ISSN:18837042)

巻号頁・発行日

no.7, pp.115-131, 2012-03-30

著者

山口 覚 Satoshi Yamaguchi

雑誌

人文論究 (ISSN:02866773)

巻号頁・発行日

vol.55, no.1, pp.153-174, 2005-05-25