著者

Naoko TSUGAWA Akiko KUWABARA Honami OGASAWARA Mayu NISHINO Kimie NAKAGAWA Maya KAMAO Hiroshi HASEGAWA Kiyoshi TANAKA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.3, pp.172-180, 2022-06-30 (Released:2022-06-30)

参考文献数

33

被引用文献数

4

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Avoidance of sunlight and self-restraint due to the COVID-19 pandemic may contribute to reduced vitamin D status. This study provides comparable data on vitamin D status in Japanese young women and assesses the effect of lifestyle, including changes caused by the COVID-19 pandemic, on vitamin D status. In study 1, 39 young healthy Japanese women aged 21–25 y were recruited from May 2016–June 2017. Serum 25-hydroxyvitamin D (25OHD) concentration and diet and lifestyle information were obtained from participants each month (n=124). In study 2, using the same parameters as study 1, young women aged 21–23 y (n=10) were recruited in September 2020. In the results of study 1, we found the frequencies of vitamin D deficiency (25OHD<20 ng/mL) in spring, summer, fall, and winter were 90.5%, 62.5%, 81.5%, and 91.3%, respectively. The substantial difference of serum 25OHD concentration was obtained in spring (Δ3.6 ng/mL) and summer (Δ5.1 ng/mL) depending on the frequency of sunscreen use (0–2 d/wk, 3–7 d/wk). In study 2, serum 25OHD concentration in September 2020 was extremely lower than in September 2016 (13.2 ng/mL vs. 21.7 ng/mL). The number of days spent outside in 2020 decreased drastically compared with 2019. In conclusion, vitamin D deficiency was highly common in Japanese women in their early 20s, and frequent sunscreen use contributed to low vitamin D status. Moreover, because the decrease in days outside due to the COVID-19 pandemic obviously resulted in a decline in vitamin D status, both appropriate sunbathing and increased dietary vitamin D intake are recommended to young women.

著者

Toshiki MAEDA Yuka HAMADA Shunsuke FUNAKOSHI Rena HOSHI Masayoshi TSUJI Aiko NARUMI-HYAKUTAKE Mai MATSUMOTO Yuya KAKUTANI Yoichi HATAMOTO Eiichi YOSHIMURA Motohiko MIYACHI Hidemi TAKIMOTO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.3, pp.189-203, 2022-06-30 (Released:2022-06-30)

参考文献数

50

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Little is known about the optimal daily magnesium (Mg) intake for individuals with high levels of physical activity. The aim of this study was to clarify the optimal dietary Mg intake for people with high levels of physical activity in a scoping review. In this review, we searched MEDLINE and Japan Medical Abstracts Society for studies published up to May 31, 2020. We conducted two searches, one for studies using gold standard measurement methods such as the balance method and factorial calculation (Search 1), and the other for studies using estimation from daily food intake (Search 2). We also performed a meta-analysis of studies that compared the Mg intake among physically active people with the Mg intake among controls. After the primary and secondary screening, 31 studies were included in the final review. All of the included studies examined professional or recreational athletes. We found no studies that examined the optimal intake of Mg using gold standard measurement methods. The Mg intake among physically active individuals was below the recommended dietary allowance in most studies. In five studies that conducted meta-analyses, physically active individuals had significantly higher intakes of Mg than controls, although these levels were still below the recommended dietary allowance. The present review revealed that evidence regarding the optimal daily magnesium intake is currently scarce, and further studies are needed.

著者

Kasumi TSUNODA Kei HAMAZAKI Kenta MATSUMURA Haruka KASAMATSU Akiko TSUCHIDA Hidekuni INADERA The Japan Environment  and Children’s Study (JECS) Group

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.69, no.1, pp.14-20, 2023-02-28 (Released:2023-02-28)

参考文献数

31

被引用文献数

1

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Many recent clinical and epidemiological studies have demonstrated the effects of vitamin D on health, yet few studies have examined the association of dietary intake of vitamin D during pregnancy with postpartum depressive symptoms. This study examined this association in a large cohort of 74,840 pregnant women who are enrolled in the longitudinal Japan Environment and Children’s Study. Dietary vitamin D intake during pregnancy (specifically after learning of the pregnancy to mid-late pregnancy) was determined using the Food Frequency Questionnaire. Postpartum depressive symptoms 1 mo after delivery were assessed using the Edinburgh Postnatal Depression Scale. Logistic regression analysis showed a reduced risk of postpartum depressive symptoms for all except the first quintile of vitamin D intake: second quintile (adjusted odds ratio [95% confidence interval]: 0.88 [0.82–0.94]), third (0.83 [0.78–0.89]), fourth (0.87 [0.81–0.93]), and fifth (0.90 [0.83–0.97]). Post-adjustment trend tests revealed a significant association between dietary vitamin D intake and postpartum depressive symptoms (p for trend=0.004). Our results revealed a higher vitamin D intake during pregnancy was associated with a lower risk of postpartum depressive symptoms 1 mo after delivery, suggesting the potential applicability of vitamin D in reducing postpartum depression.

著者

Meizhi CAI Yemei WANG Tingting LIU Yifan HUANG

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.69, no.2, pp.81-89, 2023-04-30 (Released:2023-04-30)

参考文献数

51

被引用文献数

1

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Vitamin D deficiency and inadequate calcium intake are supposed to be potentially related to cardiovascular outcomes, however, their combined association with hypertension remains unclear. In this cross-sectional study among 2,352 subjects, dietary calcium intake was assessed by using a valid food frequency questionnaire, and serum 25-hydroxyvitamin D (25OHD) was measured by the Ultra Performance Liquid Chromatography system. Hypertension was defined as a level of systolic pressure ≥140 mmHg or diastolic pressure ≥90 mmHg, or both, or administration of antihypertensive medications. Vitamin D status was classified into deficiency (25OHD<20 ng/mL), insufficiency (20 ng/mL≤25OHD<30 ng/mL) and sufficiency (25OHD≥30 ng/mL), while dietary calcium intake was divided into tertiles as low, medium, and high. Two-way analysis of variance (ANOVA) and multivariable logistic regression models were adopted. A significant interaction between vitamin D status and dietary calcium intake in relations to systolic blood pressure (p=0.042) and hypertension (p=0.029) indicates the associations of dietary calcium intake with systolic blood pressure and hypertension depend on the vitamin D status, and vice versa. Only in the vitamin D deficiency group, dietary calcium intake was significantly associated with systolic blood pressure level (β=−0.162, p<0.001) and prevalence of hypertension (odd ratio=2.20, p<0.001). The significance was not substantially compromised after further adjustment for confounding factors. In conclusion, the combination of vitamin D deficiency and low dietary calcium intake, rather than alone, is associated with hypertension.

著者

Wei HAN Muhan LI Mengyi YANG Si CHEN Yuanyuan LU Tiantian TANG Rui WANG Chenguang ZHANG Kemin QI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.69, no.2, pp.105-120, 2023-04-30 (Released:2023-04-30)

参考文献数

66

被引用文献数

4

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The effects of folic acid on body weight gain in obesity and gut microbiota-associated branched-chain amino acids (BCAAs) and mitochondrial function were investigated. Three- to four-wk-old male C57BL/6J conventional (CV) and germ-free (GF) mice were fed a high-fat diet (HD), folic acid-supplemented HD (FSHD) and a normal-fat diet (ND) for 25 wk. In CV mice, the HD-induced increases in body weight and plasma BCAA concentrations, downregulated expression of genes related to BCAA catabolism (Bcat2, Bckdha, or Ppm1k), mitochondrial biogenesis (Pgc-1α, Cox1, Nd1 or Nd6), fusion (Mfn1, Mfn2 or Opa1) and mitophagy (Pink1 or Park2), and upregulated expression of the fission-associated gene Drp1 in epididymal fat were reversely corrected with FSHD feeding. In contrast, the expression of these genes in the liver was the opposite under HD feeding or folic acid supplementation. In GF mice, plasma BCAA concentrations were much less affected by HD feeding and were reduced by FSHD feeding, with almost no alterations in the expression of genes associated with BCAA catabolism and mitochondrial function. Further analysis indicated a correlation between adipose and hepatic Mt C/N and plasma BCAA concentrations, and the latter had a close association with specific gut bacteria. Therefore, dietary folic acid supplementation differentially affected body weight gain, BCAA catabolism, and mitochondrial dynamics and metabolism under HD feeding between CV and GF mice, suggesting that gut bacteria-altered BCAAs and mitochondria might partially share the responsibility for the beneficial effects of dietary folic acid on obesity.

著者

Katsumi SHIBATA Tsutomu FUKUWATARI Satoshi SASAKI Mitsue SANO Kahoru SUZUKI Chiaki HIRATSUKA Asami AOKI Chiharu NAGAI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.59, no.3, pp.178-186, 2013 (Released:2013-07-25)

参考文献数

69

被引用文献数

11 15

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Recent studies have shown that the urinary excretion levels of water-soluble vitamins can be used as biomarkers for the nutritional status of these vitamins. To determine changes in the urinary excretion levels of water-soluble vitamins during pregnant and lactating stages, we surveyed and compared levels of nine water-soluble vitamins in control (non-pregnant and non-lactating women), pregnant and lactating women. Control women (n=37), women in the 2nd (16-27 wk, n=24) and 3rd trimester of pregnancy (over 28 wk, n=32), and early- (0-5 mo, n=54) and late-stage lactating (6-11 mo, n=49) women took part in the survey. The mean age of subjects was ~30 y, and mean height was ~160 cm. A single 24-h urine sample was collected 1 d after the completion of a validated, self-administered comprehensive diet history questionnaire to measure water-soluble vitamins or metabolites. The average intake of each water-soluble vitamin was ≈ the estimated average requirement value and adequate intake for the Japanese Dietary Reference Intakes in all life stages, except for vitamin B6 and folate intakes during pregnancy. No change was observed in the urinary excretion levels of vitamin B2, vitamin B6, vitamin B12, biotin or vitamin C among stages. Urine nicotinamide and folate levels were higher in pregnant women than in control women. Urine excretion level of vitamin B1 decreased during lactation and that of pantothenic acid decreased during pregnancy and lactation. These results provide valuable information for setting the Dietary Reference Intakes of water-soluble vitamins for pregnant and lactating women.

著者

Kumiko TAKEMORI Keisuke AKAHO Mari IWASE Minami OKANO Takashi KOMETANI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.4, pp.331-341, 2022-08-31 (Released:2022-08-31)

参考文献数

52

被引用文献数

5

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Persimmon is a fruit rich in polyphenols (proanthocyanidins or condensed tannins). Using rats and humans, the effects of Kaki-tannin (Nara-type), persimmon polyphenols prepared using a new method, on postprandial plasma glucose levels were investigated in this study. Kaki-tannin (Nara-type) comprised mainly proanthocyanidins, composed of epicatechin : epicatechin gallate : epigallocatechin : epigallocatechin gallate in a ratio of 1 : 1 : 2 : 2 with a molecular weight of approximately 8,000 Da, with epicatechin gallate as a terminal unit. These polyphenols inhibited amylolytic enzymes, such as α-amylase, maltase, sucrase, and α-glucosidase in vitro, and sodium-dependent glucose transporter 1 in Caco-2 cells. These results suggested that the polyphenols suppressed digestion and absorption in the intestinal tract. The ingestion of 250 mg/kg body weight of the polyphenols significantly suppressed increased blood glucose levels after carbohydrate (2 g/kg body weight of glucose or maltose) loading in rats. In a human trial, 1.88 g of Kaki-tannin (Nara-type) significantly delayed increased plasma glucose levels after carbohydrate (150 kcal of maltooligosaccharides) loading. Thus, Kaki-tannin (Nara-type) holds promise to be developed as a food material that potentially improve blood glucose elevation after meals.

著者

Tsuneyuki OKU Sadako NAKAMURA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.60, no.4, pp.246-254, 2014 (Released:2014-10-09)

参考文献数

32

被引用文献数

30 36

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A standardized simple, indirect method for assessing the relative energy of dietary fiber carbohydrates is not yet established. There is a need for a standardized in vivo assay. The objective of the present study was to evaluate the relative available energy (RAE) for 9 major dietary fiber materials (DFMs) based on fermentability from breath hydrogen excretion (BHE) in subjects. Fructooligosaccharide (FOS) was used as a reference. The study was conducted using a within-subject, repeated measures design and approved by the Ethical Committee of University of Nagasaki. After DFM ingestion, end-expiratory gas (750-mL) was collected at 1-h intervals for 8 h, as well as at 2-h intervals between 8 h and 14 h, and 30 min after waking up and 24 h after DFM ingestion. Breath hydrogen concentration was assessed with a gas chromatograph. The RAE of DFMs tested was evaluated based on the area under the curve (AUC) of BHE of FOS. Based on the ratio of AUC for 8 h, the RAE of polydextrose, partially hydrolysed guar gum, resistant maltodextrin and partially hydrolysed alginate was 1 kcal/g, and that of glucomannan, heat-moisture treatment and high-amylose cornstarch and cellulose was 0 kcal/g, while the RAE of all tested DEMs including cellulose and glucomannan was 1 kcal/g in the calculation based on AUCs for 14 h and 24 h in subjects. We suggest that a breath hydrogen collection period of 14 h or more could be used to measure RAE for a range of fiber preparations in vivo.

著者

Hsin-Yi YANG Wan-Hsuan WANG Jun-Ye ZHAN Ya-Ling HUANG Wei-Yi CHENG

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.66, no.Supplement, pp.S356-S360, 2020 (Released:2021-02-22)

参考文献数

25

被引用文献数

3

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Overweight and obesity are associated with many chronic diseases. This study aimed to clarify the possible effects of consuming golden kiwifruit as daily fruit intake on body composition, lipid metabolism and inflammatory responses. Methods: We recruited twenty-two overweight and obese subjects and they were asked to consume two golden kiwifruit every day during the 6-wk experimental period. At the baseline and end of the study, fasting blood samples were collected and anthropometric and blood pressure measurement were conducted. Results: During the experimental period, no adverse effect and dropout were reported. At the end of the study, a significant decrease in body fat and circulatory tumor necrosis factor (TNF)-α concentration were found. In addition, there was a reduction of angiotensin II (AgII) concentration and systolic blood pressure in subjects with baseline systolic blood pressure (SBP) ≥125 mmHg. Conclusion: Our results suggested that daily golden kiwifruit intake can reduce body fat mass, improve blood pressure and regulating inflammatory responses in overweight and obese young adults.

著者

Madoka KOHNO Anayt ULLA Rina TANIGUCHI Akane OHISHI Kako HIRAYAMA Yuma TAKEMURA Shoichiro TAKAO Yuki KANAZAWA Yuki MATSUMOTO Masafumi HARADA Tomoya FUKAWA Hiro-omi KANAYAMA Takayuki UCHIDA Toshio SUZUKI Takeshi NIKAWA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.6, pp.521-526, 2022-12-31 (Released:2022-12-31)

参考文献数

21

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Various dietary protein supplements are used by the elderly and bedridden to maintain their skeletal muscle mass and functions. High-quality proteins act as an anabolic driver and help to improve muscle strength and performance. Previously, we reported that soy protein significantly attenuates denervation-induced loss of muscle mass and myofiber cross sectional area in mice with inhibition of ubiquitination and degradation of IRS-1 in tibialis anterior muscle. It also increased muscle volume and strength in bedridden patients. In the present study, we investigated the effects of dietary soybean supplementation on muscle functions in taxi drivers lacking vigorous physical exercise. We conducted a case-control study on 25 healthy, male taxi drivers between the ages of 36 and 71 y performing minimal physical exercise. They were divided into two dietary groups: the soybean diet group (n=13) who ate daily meals (dinner) supplemented with 50 g of steamed soybean for 30 d and the control diet group (n=12) who received no soybean supplement. Next, we measured the muscle cross-sectional area (CSA) and muscle strength and function in both the groups before and after 30 d of soybean intake. The body weights of both diet groups did not differ significantly over time. However, after 30 d of soybean supplementation, the soybean-fed group developed significantly higher muscle CSA and grip strength compared to the control groups. In conclusion, dietary soybean supplementation improved muscle function in taxi drivers who lacked exercise.

著者

Qian LIANG Quanjun LYU Mengying FAN Zhenxing MAO Chongjian WANG Yuqian LI Songyang CUI Kailin NIU Ruohua GU Linlin LI

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.5, pp.399-408, 2022-10-31 (Released:2022-10-31)

参考文献数

46

被引用文献数

1

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The purpose of this study was to examine the association between dietary protein intake and the risk of type 2 diabetes mellitus (T2DM) among a Chinese rural elderly population. We used the demographic and dietary information of adults over age 65 in the Henan Rural Cohort Study to identify and pair 950 T2DM patients with healthy controls in a 1 : 1 matched case-control study. Dietary data was collected through a Food Frequency Questionnaire. A multivariate logistic regression model was applied to calculate the odds ratio (OR) and 95% confidence interval (CI) of T2DM risk according to protein intake. After adjustment for confounding factors, higher intake of total protein was negatively associated with T2DM risk in the total population (extreme-tertile OR=0.75, 95% CI: 0.58–0.93) and women (extreme-tertile OR=0.84, 95% CI: 0.47–0.93). Multivariate-adjusted ORs for the risk of T2DM in the highest compared with lowest tertile of plant protein intake in the total population and in women were 0.86 (95% CI: 0.60–0.84) and 0.58 (95% CI: 0.36–0.95), respectively. Our results suggest that the protein intake, especially plant protein, has a significant association with the risk of T2DM in rural elderly populations, and the sources of protein may be also important in future guidelines.

著者

Khushwant S. BHULLAR Nan SHANG Jianping WU

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S113-S115, 2022-11-30 (Released:2022-11-25)

参考文献数

17

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Bone health is an important medical concern in rapidly aging demographics worldwide. Excessive bone resorption, due to enhanced activity of osteoclasts, is a major underlying cause of bone disorders such as osteoporosis. Inflammation and oxidative stress are key factors contributing to increased osteoclastic activity. Like increased activity of osteoclasts, depletion of osteoblasts also contributes to weakened structural integrity of bone. Considering the epidemiology of bone disorders and aging demographics there is a substantial need for novel bone health therapeutics. IRW (Ile-Arg-Trp), an egg-derived tripeptide, exhibits a spectrum of pharmacological activity. In our recent work, we have shown that IRW inhibits osteoclastogenesis and promotes osteogenesis in the mouse macrophage RAW 264.7 and MC3T3-E1 cells. IRW treatment (25 and 50 μM) significantly inhibited osteoclastogenesis-associated factors [TRAF6 (TNF Receptor Associated Factor 6), Fos Proto-Oncogene (c-Fos), Nuclear Factor of Activated T Cells 1 (NFATc1), and cathepsin K] and upregulated osteogenesis-associated factors [RUNX2 (Runt-related transcription factor 2) and RANKL (Receptor activator of nuclear factor kappa-B ligand)] in the two cell lines. Currently, we are conducting studies to analyze the impact of IRW on Angiotensin II (Ang II)-induced stress in vitro and in vivo. In summary, our recent work presents the ability of IRW to prevent LPS-induced inflammatory bone resorption and activation of osteogenesis activity via multiple signaling pathways.

著者

Katsumi SHIBATA Akiko TACHIKI Kana MUKAEDA Tsutomu FUKUWATARI Satoshi SASAKI Yoshiki JINNO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.59, no.4, pp.343-346, 2013 (Released:2013-09-24)

参考文献数

25

被引用文献数

3 6

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Most Japanese women do not consume the estimated average requirement of vitamin B6 (1.7 mg/d) during pregnancy. Nevertheless, these deficiencies are not reported. We investigated a nutritional biomarker of vitamin B6 in pregnant Japanese women as well as their vitamin B6 intakes. Vitamin B6 intakes in the first, second, and third trimesters of pregnancy, and 1 mo after delivery were 0.79±0.61 (n=56), 0.81±0.29 (n=71), 0.90±0.35 (n=92), and 1.00±0.31 (n=44) mg/d, respectively. Plasma pyridoxal 5'-phosphate (PLP) concentrations in the first, second, and third trimesters of pregnancy, and 1 mo after delivery were 57.1±27.6 (n=56), 23.3±16.7 (n=71), 18.3±12.5 (n=92), and 43.9±33.4 (n=44) nmol/L, respectively. The plasma concentrations significantly decreased in the second and third trimesters of pregnancy compared to values from the first trimester (p<0.05), and these concentrations returned to the values of the first trimester of pregnancy 1 mo after birth.

著者

Kota SHIOZAWA Afifah Zahra AGISTA Yusuke OHSAKI Hitoshi SHIRAKAWA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S8-S10, 2022-11-30 (Released:2022-11-25)

参考文献数

19

被引用文献数

1

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Vitamins are a family of micronutrients comprising 13 groups of organic compounds, of which vitamin B1 was identified first, approximately 110 y ago. Deficiency of each vitamin results in specific symptoms, such as neuropathy, dermatitis, diarrhea, dementia, pernicious anemia, scurvy, blindness, rickets, and bleeding. Almost all vitamins can modulate the functions of enzymes and/or other proteins involved in the formation of bone and soft tissues, generation of energy, and regulation of homeostasis via specific vitamin–protein interactions. In addition to the well-known physiological roles of vitamins, novel modes of action of vitamins have been elucidated. These new functions could contribute to extending healthy life expectancy by preventing and curing lifestyle-related diseases. In this mini-review, we introduce the functional properties of three vitamins, vitamin B3 (niacin), biotin, and vitamin K, for the prevention of age-related diseases.

著者

Kazunori UTSUNOMIYA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S64-S66, 2022-11-30 (Released:2022-11-25)

参考文献数

11

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The type 2 diabetes (T2DM) pandemic in Asian countries has become an urgent problem to be solved for each country from a socioeconomic viewpoint, because the expense for management of diabetic complications is rapidly increasing. This is due to Westernization of lifestyle in Asian countries, which results in a greater prevalence of visceral obesity. Thus far, it is believed that impaired insulin secretion from pancreatic islets mainly contributes to the pathogenesis of T2DM in Asians. However, insulin resistance clearly underlies the prevalence of T2DM in Asian countries, as well as Western countries. Lifestyle intervention, including exercise and diet is an essential approach in care for patients with T2DM. In particular, nutrition therapy is a fundamental treatment that aims to correct overweight and improve insulin resistance. The principal requirement of nutrition therapy consists of energy restriction and a well-balanced intake of various nutrients. The lifestyle of people in Asian countries has dramatically changed in recent decades due to economic growth, which has made it difficult to provide guidelines for nutrition therapy. The uniform setting of nutrition goals is difficult to achieve because of diversity in eating patterns. This symposium aims to promote optimal nutrition therapy for T2DM through comparing the guidelines of different countries, including Korea, Japan, and the United States. Interactive talks among speakers are expected to yield a new perspective in nutrition therapy for the management of T2DM.

著者

Takumi KAWAGUCHI Akinobu KATO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S73-S75, 2022-11-30 (Released:2022-11-25)

参考文献数

27

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Evidence-based Clinical Practice Guidelines for Liver Cirrhosis were updated in 2021 by The Japanese Society of Gastroenterology/Japan Society of Hepatology. In the guidelines, the flowchart for nutritional therapy was revised based on accumulated evidence. In particular, sarcopenia is incorporated as an assessment for nutritional status. In addition, late evening snack is repositioned as a 1st-line nutritional therapy. Furthermore, recent study demonstrated unforeseen pharmacological actions of branched-chain amino acids including improving sarcopenia and prognosis. In this mini-review, we summarize the updated points for nutritional therapy for patients with liver cirrhosis.

著者

Mayo HIGASHIHARA Rena FUJISHIMA Hirona KUGO Tatsuya MORIYAMA Nobuhiro ZAIMA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S143-S145, 2022-11-30 (Released:2022-11-25)

参考文献数

19

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Dietary habit is closely associated with healthspan. Functional food factors are key to maintaining a health metabolism in our bodies. Because functional food factors are main components to determine the quality of foods, many technologies have been established to analyze functional factors in foods. High-performance liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is a solid approach to detect functional food factors with high sensitivity and specificity. Findings obtained from these mass spectrometric approaches play essential roles in estimating the quality of foods. However, these technologies are not available for the analysis of the spatial distribution of molecules of interest in foods. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is considered an ideal approach to visualize distribution of molecules in foods. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without purification, separation, or labeling. MALDI-MSI can be used to visualize the spatial distribution of wide range of food components including protein, peptides, amino acids, lipids, carbohydrate, and vitamins. Although the methodology of MALDI-MSI in food science is not yet fully established, the versatility of MALDI-MSI is expected to open a new frontier in food science. In this mini review, we briefly summarized the applications of MALDI-MSI in the field of food science.

著者

Shengmin SANG

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S124-S125, 2022-11-30 (Released:2022-11-25)

参考文献数

9

被引用文献数

2

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Consumption of tea has been associated with many health benefits including the prevention of cardiovascular disease, cancer, and obesity. These effects are attributed to the polyphenol compounds in tea with catechins being the major components in green tea and theaflavins (TFs) and thearubigins (TRs) as the unique compounds in black tea. Tea polyphenols are extensively metabolized in vivo and have poor systematic bioavailability. It is generally believed that the metabolites of tea polyphenols retain their bioactivities and some of the microbial metabolites are more bioavailable than the parent compounds. This manuscript summarizes the recent progress on the identification of novel metabolic pathways of tea polyphenols and their contributions to the health benefits of tea.

著者

Satoshi HACHIMURA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S126-S127, 2022-11-30 (Released:2022-11-25)

参考文献数

7

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Recent studies have revealed that various food components affect the immune response. It has been shown that such components could act on the intestinal immune system. On the other hand, intestinal microbiota and their metabolites affect intestinal immunity. Such findings suggest the possibility that food components could act on the intestinal immune system directly, indirectly through intestinal microbiota, or through collaborative immunomodulation by both.

著者

Jun KUNISAWA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.68, no.Supplement, pp.S23-S25, 2022-11-30 (Released:2022-11-25)

参考文献数

13

被引用文献数

1

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The intestinal environment, formed from dietary components and intestinal bacteria, plays a pivotal role in maintaining our health. Most studies have focused on the functions of dietary components and intestinal bacteria, separately. However, with the new concept of postbiotics, bacterial metabolites produced from food components as substrates, research including the perspective of the interaction between dietary components and intestinal bacteria has become important. In this paper, the importance of food is presented, including the viewpoint of postbiotics, in relation to the interaction between the intestinal environment and health.