著者

Md.Sofiqul ISLAM Noriko HIRAISHI Mohannad NASSAR Ryohei SONO Masayuki OTSUKI Tsutomu TAKATSURA Cynthia YIU Junji TAGAMI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.31, no.3, pp.362-367, 2012 (Released:2012-05-28)

参考文献数

36

被引用文献数

18 29

---

The aims of this study were to investigate the effects of hesperidin, a citrus flavonoid, on human root dentin demineralization and collagen preservation, and compare it with chlorhexidine and grape seed extract. Specimens were assigned to different treatment groups: hesperidin, chlorhexidine and grape seed extract. Specimens were subjected to pH cycling by demineralization for 14 h, incubation in testing solutions for 2 h and remineralization in presence of bacterial-derived collagenase for 8 h, for 8 days. Calcium release was measured by means of an atomic absorption spectrophotometer, and degraded collagen matrix was investigated by hydroxyproline assay. Specimens were assessed longitudinally with transverse micro-radiography to investigate lesion depth and mineral loss. In hesperidin and grape seed extract groups, demineralization was reduced when the collagen matrix was preserved. The hesperidin group showed the lowest value in lesion depth and mineral loss, indicating that hesperidin inhibited demineralization and probably enhanced remineralization even under fluoride-free conditions.

著者

Mohammed M GAD Ahmed RAHOMA Ahmad M Al-THOBITY

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2017-191, (Released:2018-06-20)

参考文献数

42

被引用文献数

21

---

The current study evaluated the effects of autoclave polymerization both with and without glass fiber (GF) reinforcement on the surface roughness and hardness of acrylic denture base material. Ninety disc specimens (30×2.5 mm) were prepared from Vertex resin and divided according to polymerization techniques into a water bath, short and long autoclave polymerization groups. Tested groups were divided into three subgroups according to the GF concentration (0, 2.5, and 5 wt%). Profilometer and Vickers hardness tests were performed to measure surface roughness and hardness. ANOVA and Tukey-Kramer multiple comparison tests analyzed the results, and p≤0.05 was considered statistically significant. Autoclave polymerization significantly decreased the surface roughness and increased the hardness of acrylic resin without GF reinforcement (p<0.05). However, 5 wt% GF addition significantly increased surface roughness and decreased hardness of the autoclave polymerized denture base resin (p<0.05). Surface properties of Polymethyl methacrylate (PMMA) denture base material improved with autoclave polymerization and negatively affected with GFs addition.

著者

Aye KO KO Naoko MATSUI Ayako NAKAMOTO Masaomi IKEDA Toru NIKAIDO Michael F. BURROW Junji TAGAMI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.39, no.3, pp.407-414, 2020-05-27 (Released:2020-06-05)

参考文献数

32

被引用文献数

11 16

---

The purpose of this study was to evaluate the effects of two different concentrations of silver diammine fluoride (SDF) on dentin bonding performance. Human mid-coronal dentin was treated with either distilled water (control), 3.8%SDF or 38%SDF for 3 min. A two-step self-etch adhesive and resin composite were applied according to manufacturer’s instructions. After thermocycling (TC) at 0, 5,000 and 10,000 cycles, microtensile bond strength (µTBS) testing and morphological assessment of resin-dentin bonding interface were performed. At 0 TC, µTBSs of 3.8% and 38%SDF were significantly reduced (p<0.05). At 5,000 and 10,000 TC, µTBSs of 3.8%SDF were comparable to those of the control group, whereas the µTBSs of 38%SDF were significantly lower (p<0.05). Acid-base resistance zone formation was observed in all groups, however, slope-shaped formation was identified only in the SDF groups. The µTBSs and interfacial morphology were influenced by concentration of SDF and also TC.

著者

Motohiro UO Tsukasa AKASAKA Fumio WATARI Yoshinori SATO Kazuyuki TOHJI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.30, no.3, pp.245-263, 2011 (Released:2011-06-02)

参考文献数

106

被引用文献数

49 66

---

After the discovery of fullerene and carbon nanotubes, various carbon nanomaterials were discovered or synthesized. The carbon nanomaterials have remarkable properties, different from bulk materials with the same chemical composition, and are therefore useful for industrial applications. However, the toxicity of nanomaterials may also differ from that of the bulk materials; this difference poses a concern. The physical similarity of nanomaterials to asbestos has led to evaluations for toxicity by many researchers using various methods. In this review, we compile and compare the toxicity evaluations of each carbon nanomaterial.

著者

Imran FAROOQ Abdul Samad KHAN Imran Alam MOHEET Emad ALSHWAIMI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2020-078, (Released:2020-11-19)

参考文献数

24

被引用文献数

7

---

The aim was to synthesize a toothpaste and analyze its effect on surface micro-hardness and roughness of enamel. Basic paste was prepared by using basic ingredients. Theobromine (0.2 wt%) and laboratory synthesized fluoridated-bioactive glass (F-BG, 4 wt%) were added to it. Post-demineralization, 36 enamel blocks were divided into six groups that were brushed with their respective toothpaste+artificial saliva (AS): group 1 (control): basic paste; group 2: basic paste+theobromine; group 3: commercial theobromine toothpaste; group 4: commercial BG toothpaste; group 5: basic paste+F-BG; and group 6: basic paste+theobromine+F-BG. On micro-hardness analysis, group 6 performed best, followed by group 4. Surface roughness results showed the maximum decrease in roughness values for group 6, followed by group 5. Treatment with toothpaste composition containing theobromine+F-BG resulted in the enamel’s increased micro-hardness and decreased surface roughness.

著者

Tool SRIAMPORN Niyom THAMRONGANANSKUL Chumphol BUSABOK Sushit POOLTHONG Motohiro UO Junji TAGAMI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.33, no.1, pp.79-85, 2014-01-30 (Released:2014-02-01)

参考文献数

65

被引用文献数

27 70

---

The surface morphology and crystal structure change of dental zirconia after hydrofluoric acid (HF) etching were evaluated. Four groups of sintered zirconia specimens were 1) control group, 2) immersion in 9.5%HF at 25oC for 1, 2, 3, or 24 h, 3) immersion in 9.5%HF at 80oC for 1, 3, 5, or 30 min and 4) immersion in 48%HF at 25oC for 30 or 60 min. The specimens were evaluated under SEM and XRD. The SEM analysis revealed changes in surface topography for all the HF-etched zirconia specimens. The irregularities surface increased with increasingly longer immersion times and higher etching solution temperatures. The XRD analysis of the HFetched zirconia specimens revealed the presence of a crystalline monoclinic phase along with a tetragonal form. It was concluded HF can etch dental zirconia ceramic, creating micro-morphological changes. Tetragonal-to-monoclinic phase transformation was induced on the etched zirconia surface.

著者

Maryam MOSHAVERINIA Ali BORZABADI-FARAHANI Abdi SAMENI Alireza MOSHAVERINIA Sahar ANSARI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.35, no.5, pp.817-821, 2016-09-29 (Released:2016-10-01)

参考文献数

25

被引用文献数

6 24

---

Present study evaluated effects of addition of Nanoparticles fluorapatite (Nano-FA) on microhardness and fluoride release of a Glass Ionomer Cement (GIC, Fuji IX GP Fast). Forty-eight specimens prepared, divided equally into 4 groups (2 with Nano-FA); after 24 h and one week Vickers microhardness (HV) was measured. Nano-FA specimens were made from addition of nano-FA to Fuji IX powder (glass powder/Nano-FA ratio=20:1 wt/wt, 3.6:1 P/L ratio). At 24 h, mean (95% CI) HV for GIC and Nano-FA GIC were 40.59 (39.51–41.66) and 46.89 (45.95–47.82) kg/mm2, and at one week 44.98 (44.23–45.72), 53.29 (52.58–53.99) kg/mm2, respectively. Findings indicated higher HV in Nano-FA specimens (F=221.088, p<0.001). Twenty-eight days weekly cumulative fluoride release in both groups was not different (p>0.05). MTT assay exhibited no inhibition of cell proliferation or reduction in metabolic activity in experimental [84.0 (3.3)] or control groups [85.1 (4.7)] with no difference between groups (p>0.05). New nano-FA GIC was biocompatible and showed improved surface hardness. Future clinical trials can verify the usefulness of Nano-FA GIC.

著者

Makoto NODA Yuji OKUDA Jiro TSURUKI Yoshito MINESAKI Yasumi TAKENOUCHI Seiji BAN

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.29, no.5, pp.536-541, 2010 (Released:2010-10-14)

参考文献数

21

被引用文献数

58 50

---

The purpose of this study was to characterize the surface damages of zirconia by Nd:YAG dental laser irradiation through a systematic evaluation of the associated microstructural changes. Disk specimens of yttria-stabilized tetragonal zirconia polycrystals (Y-TZP) and ceria-stabilized zirconia/alumina nanocomposite (Ce-TZP/Al2O3 nanocomposite) were irradiated by Nd:YAG dental laser. The specimens were characterized using scanning electron microscopy, X-ray diffractometry, and wavelength dispersive X-ray spectroscopy. Every single irradiated spot was indicated by a circular black pit surrounded by a circular raised rim with a sunken depression at the center. On surface changes, many cracks were formed inside each irradiated pit. On changes in elemental composition, the concentration of oxygen decreased while that of zirconium increased. After heating in air, the assembly of circular black pits turned white, although the depression and raised rim remained. This study showed that Nd:YAG dental laser irradiation induced cracking and reduced oxygen content on the surface of zirconia. Consequently, these phenomena reduced the mechanical strength of zirconia. Therefore, Nd:YAG dental laser welding should not be performed on tetragonal zirconia.

著者

Koji HAYASHI Ryo ISHII Tosihiki TAKAMIZAWA Shunichi SUDA Ryota AOKI Kana HAYASHI Atsushi KAMIMOTO Masashi MIYAZAKI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2023-073, (Released:2023-11-23)

参考文献数

29

---

This study aimed to evaluate the influence of surface pretreatment on the shear bond strength of resin luting cement to saliva-contaminated resin core foundation. The surface free energy (γS) of the adherent surfaces was examined. The two-way analysis of variance revealed that the surface pretreatment and storage conditions had a significant effect on the strength of the bond to resin core foundation. The γS values of the saliva-contaminated group were significantly lower than those of the other groups, and they tended to improve after surface pretreatment. The tendency of improvement in γS values differed depending on the type of pretreatment agents. Surface treatment with solutions containing functional monomers is effective in removing saliva contaminants from the resin core foundation surfaces and in creating an effective bonding surface for the resin luting cement.

著者

Hiroyasu KOIZUMI Haruto HIRABA Takayuki YONEYAMA Akihiro KUROIWA

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2023-113, (Released:2023-08-22)

参考文献数

63

---

This review describes individual studies of removable dental prostheses, evaluated their performance and clinical applicability for the proposal to expand health insurance coverage of titanium and its alloys to removable dental prostheses. Titanium and its alloys have become clinically applicable as prosthetic materials by improving dental casting systems. They have high biosafety and good mechanical properties, are excellent substitutes for the silver-palladium-gold alloys for casting, and are highly useful for removable dental prostheses. Therefore, the introduction of health insurance coverage for removable dental prostheses made of titanium and its alloys is worthy of consideration.

著者

Kana HAYASHI Hiroyasu KUROKAWA Makoto SAEGUSA Ryota AOKI Toshiki TAKAMIZAWA Atsushi KAMIMOTO Masashi MIYAZAKI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2023-007, (Released:2023-07-15)

参考文献数

29

---

This study aimed to determine the influence of surface roughness of the color adjustment potential restoration of universal resin composites. A structural colored resin composite (Omnichroma, OC) and a pigment-employed universal shade resin composite (Beautifil Unishade, BU) were used. Each resin composite was placed in a cavity to determine its ability to match the color of artificial teeth. The surface of the resin composites was polished with #800- or #2000-grit SiC paper before performing color measurements. One-way analysis of variance and Tukey post hoc tests were performed (α=0.05). The color difference (ΔE*ab) ranged from 2.5–3.9 for OC and 1.8–8.7 for BU. OC has a more stable color adjustment than BU. The color adjustment potential of universal resin composites was affected by the surface roughness of the restorations.

著者

Abdullah KAMEL Toshiki YAMAZAKI Natsuko MURAKAMI Huaxin LYU Kohei KOMINE Amr BADR Gehan FEKRY Hidekazu TAKAHASHI Noriyuki WAKABAYASHI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.42, no.3, pp.336-342, 2023-05-25 (Released:2023-05-30)

参考文献数

35

---

This study aimed to evaluate the retentive force of polyetheretherketone (PEEK) and zirconia secondary crowns on ready-made titanium implant abutments (with height, diameter, and taper as 5.5 mm, 4.5 mm, and 6°, respectively) as the primary crown. PEEK, zirconia, and titanium secondary crowns were fabricated using a CAD/CAM system. Insertion and removal tests of secondary crowns on the primary crown were conducted for 2,000 cycles. The initial retentive forces recorded at the 100th cycle for PEEK, zirconia, and titanium were 13.0±7.9, 2.9±2.6, and 27.6±1.7 N, respectively. The retentive forces of PEEK and zirconia showed no significant difference among all cycles. However, the retentive force of the titanium used as a control decreased (20.3±2.8 N) significantly at the 2,000th cycle. Although the retentive force of PEEK was lower than that of titanium, it was within the range that can provide a suitable retentive force of 5 N for removable dental prostheses.

著者

Mitsunori UNO Hajime ISHIGAMI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.42, no.1, pp.105-111, 2023-01-25 (Released:2023-01-31)

参考文献数

20

被引用文献数

2

---

In this study, a new shear bonding system was created that uses a CO2 laser to form a pattern of conical spots on a zirconia prosthesis surface to improve mechanical interlocking. Four types of zirconia substrates were employed, which underwent particle abrasion after being polished, machined, spotted, and spot-particle abraded. The surface roughness of each substrate was measured via scanning electron microscopy and X-ray diffraction (XRD). A shear bond strength test was performed with the zirconia-based material and a composite resin assuming abutment construction. XRD did not indicate that forming spots caused a phase transformation in zirconia with respect to machined zirconia. The shear bond strength was approximately twice that of the machined samples and approximately 2.3 times that of the samples that underwent particle and spot-particle abrasion. Surface modification by spotting improved the mechanical fitting force. However, no significant difference was observed between particle abrasion and spot-particle abrasion.

著者

Yuan ZHANG Tao YANG Beibei LI Jun LI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.42, no.3, pp.449-457, 2023-05-25 (Released:2023-05-30)

参考文献数

40

被引用文献数

1

---

The aim of this study was to assess the shear bond strength and durability between plasma-pretreated and polydopamine (PDA)-coated zirconia and titanium. Four groups were prepared according to the different surface treatments (untreated ZrO2, plasma-pretreated ZrO2, PDA-coated ZrO2, and plasma-pretreated and PDA-coated ZrO2 (PP+PDA-ZrO2). The surface topography and roughness, contact angle, and elemental analysis of the coatings of the four groups were investigated, and the bond strength and durability of the specimens were evaluated based on shear bond strength and thermocycle tests. Physical and chemical characterization results confirmed that PDA coatings can be successfully formed on zirconia substrates. The roughness and hydrophilicity were significantly higher in the PP+PDA-ZrO2 group, which demonstrated better shear bond strength and durability between zirconia and titanium. The plasma pretreatment of zirconia substrates can enhance the stability of the PDA coating layer, and hybrid surface modifications can provide several bonding advantages for clinical use.

著者

Wenqi DENG Jun-ichiro JO Hidetoshi MORIKUNI Satoshi SASAYAMA Yoshiya HASHIMOTO Naoyuki MATSUMOTO Yoshitomo HONDA

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.42, no.3, pp.351-359, 2023-05-25 (Released:2023-05-30)

参考文献数

52

---

Senescence-associated secretory phenotype (SASPs) secreted from senescent cells often cause the deleterious damages to the surrounding tissues. Although dedifferentiated fat (DFAT) cells prepared are considered a promising cell source for regenerative therapies, SASPs from DFAT cells undergoing long-term cell culture, which latently induce replicative senescence, have barely been explored. The present study was designed to investigate senescent behaviors in rat-derived DFAT cells at high passage numbers and to analyze the possible types of SASPs. Our data show that DFAT cells undergo senescence during replicative passaging, as determined by multiple senescent hallmarks including morphological changes in cell shape and nucleus. Moreover, RT2 PCR array analysis indicated that senescent DFAT cells expressed higher levels of 16 inflammatory cytokines (Ccl11, Ccl12, Ccl21, Ccl5, Csf2, Cxcl1, Cxcl12, Ifna2, IL11, IL12a, IL13, IL1a, IL1rn, IL6, Mif, and Tnf) associated with SASPs than non-senescent cells. This study implicates that rat DFAT cells undergo cellular senescence after long-term cell culture; cautious consideration should be paid to treat SASP secretion when senescent DFAT cells are used in regenerative medicine.

著者

Ji-Hyun JANG Myoung Geun LEE Sang Uk WOO Chung Ok LEE Jin-Kyu YI Duck-Su KIM

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.35, no.4, pp.606-612, 2016-07-29 (Released:2016-07-30)

参考文献数

33

被引用文献数

33 34

---

This study compared the dentin bond strength of a new universal adhesive with that of contemporary multi-step dentin adhesives. Six experimental groups were prepared according to the adhesives used and their application modes: Optibond FL (OB), Adper Single Bond Plus (SB), One-Step Plus (OS), Clearfil SE Bond (CS), All-Bond Universal using etch-and-rinse mode (ABE), and AllBond Universal using self-etch mode (ABS). Micro-tensile bond strength (µTBS) and failure mode were evaluated for each group. The bonded interface was analyzed using transmission electron microscopy (TEM). As a result, µTBS of 6 experimental groups was followed as: OB=ABE=SE=ABS>SB>OS group. TEM micrographs of ABE and ABS groups revealed a homogenous adhesive layer formation. In conclusion, a new universal adhesive can make reliable bond to dentin, regardless of the application mode.

著者

Haruto HIRABA Hiroyasu KOIZUMI Hiroshi NOGAWA Kosuke TAKEHANA Takayuki YONEYAMA Hideo MATSUMURA

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2022-273, (Released:2023-04-28)

参考文献数

17

---

This study investigated the effect of 10-methacryloyloxydecyl dihydrogen phosphate (MDP) in methyl methacrylate (MMA) monomer on the adhesion of tri-n-butylborane (TBB)-initiated resins (MDP/MMA-TBB resins) to human enamel. Enamel surface conditions were either polished only or phosphatized surfaces. The 1.0, 1.7, and 2.0 mol% MDP/MMA-TBB resins, 4-methacryloxyethyl trimellitate anhydride (4-META)/MMA-TBB resin and MMA-TBB resin were prepared as luting materials. The shear bond strength was determined before and after thermocycles, and the results were compared using non-parametric statistical analyses (each, n=15). The MDP/MMA-TBB resins showed significantly better bond durability to enamel than other resins with or without etching. The 1.7 and 2.0 mol% MDP/MMA-TBB resins were suggested to be the optimum MDP concentrations from pre- and post-thermocycling results for the non-etched specimens. The TBB initiator resin including MDP was shown to be effective in bonding to human enamel, and this effect was enhanced in combination with phosphate treatment.

著者

Takeshi WADA Hiroyasu KOIZUMI Haruto HIRABA Takao HANAWA Hideo MATSUMURA Takayuki YONEYAMA

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2022-184, (Released:2023-03-18)

参考文献数

36

---

This study evaluated the effect of luting system with acidic primers on the durability of bonds with Ti-15Mo-5Zr-3Al titanium alloy (Ti-15Mo-5Zr-3Al) and its component metals. Adherend metals were Ti-15Mo-5Zr-3Al, Ti, Mo, Zr, and Al. Four primers were evaluated as adhesion promoters: Alloy Primer (ALP), Estenia Opaque Primer (EOP), M. L. Primer (MLP), and Super Bond liquid (SBL). An acrylic resin was used as the luting material. Pre- and post-thermocycling shear bond strength was determined to evaluate the bonding durability, and the results were compared using non-parametric statistical analyses (n=11/group). The post-thermocycling bond strength in MPa (median) associated with ALP, EOP, MLP, and SBL were 18.8, 19.8, 4.1, and 0.8, respectively, for Ti-15Mo-5Zr-3Al. The results showed that two primers containing 10-methacryloyloxydecyl dihydrogen phosphate (MDP) were effective for the durability of bonding of Ti-15Mo-5Zr-3Al to the resin. MDP enhanced the bonding durability of the resin bonded to either Ti, Zr, or Al.

著者

Watcharapong TONPRASONG Masanao INOKOSHI Muneaki TAMURA Keita HATANO Shunsuke MINAKUCHI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.42, no.1, pp.49-54, 2023-01-25 (Released:2023-01-31)

参考文献数

31

被引用文献数

2

---

Although a surface pre-reacted glass ionomer (S-PRG) exerts a suppressive effect on Candida albicans (C. albicans) activity and growth, its influence on the expression of the lipase gene (LIP) family including LIP1–LIP10, an indicator of clinical infection, has not yet been investigated. Therefore, in this study, we evaluated the effect of S-PRG filler eluates on LIP expression in C. albicans using real-time reverse-transcription polymerase chain reaction. Candida albicans was treated with an S-PRG filler diluted at ratios of 1:32 and 1:64 for 24 h at 37°C. The diluted S-PRG filler eluates (1:32) suppressed lipase activity in C. albicans by downregulating LIP5 (0.54±0.25 relative to that of the control) and LIP8 (0.35±0.074) expression after 24 h, which corresponded with decreased lipase activity. At a dilution factor of 1:64, there was no significant difference in LIP expression. Thus, the S-PRG filler eluate has potential to suppress fungal activity by downregulating LIP expression.

著者

Takeshi NAKAMURA Makoto HAYASHI Muneaki TAMURA Masahiro KAKETANI Tomoka ITO Toshiki TAKAMIZAWA Yusuke SUZUKI Takuya YASUKAWA Akiyoshi SUGAWARA Osamu TAKEICHI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

pp.2022-250, (Released:2023-03-18)

参考文献数

32

---

The recently developed biphasic calcium phosphate cement (BCPC) consists of α-tricalcium phosphate-tetracalcium phosphate as the solid phase and calcium phosphate solution as the liquid phase. BCPC powder is composed of a single solid solution with a monomodal size distribution. Here, we used a bacterial leakage model to examine the utility of BCPC as a seal for root-end filling. We prepared large (median particle size=9.96 µm; BCPC-L) and small (median particle size=4.84 µm; BCPC-S) BCPC powders. In total, 45 single-rooted teeth were instrumented, resected at the root-end, and retrofilled with experimental materials. Mineral trioxide aggregate (MTA) was used as the control. After visual confirmation of BCPC powder size and retrofilling quality by microscopy, bacterial leakage tests were conducted using Enterococcus faecalis. The bacterial leakage tests did not reveal any significant differences between BCPC-S and MTA. Our findings suggest that BCPC-S is useful for root-end filling.