著者

堀 雅明 中井 斌

出版者

日本保健物理学会

雑誌

保健物理 (ISSN:03676110)

巻号頁・発行日

vol.11, no.1, pp.1-11, 1976 (Released:2010-02-25)

参考文献数

37

被引用文献数

1 1

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Genetic risk assessment for potential hazard from environmental tritium to man becomes important with increasing nuclear-power industry. The purpose of this short review is to discuss the possible genetic effects of tritium from a view of genetic risk estimation.The discussion is based mainly on our experimental results on the chromosome aberrations induced in human lymphocytes by tritium at the very low-level. The types of chromosome aberrations induced by radiation from tritium incorporated into the cells are mostly chromatid types. The most interesting finding is that the dose-response relationship observed in both tritiated-water and tritiated-thymidine is composed of two phases. The examination on the nature of two-phase dose-response relationship is very important not only for the mechanisms of chromosome aberrations, but also for the evaluation of genetic risk from low-level radiation.