文献一覧: 井上舞 (著者)

11 0 0 0 OA 溶出性・分割性からみた市販アセトアミノフェン坐剤の比較

著者: 黒田裕子徳田真実井上舞鳥増田克哉寺島朝子前澤佳代子松元一明木津純子
出版者: 一般社団法人日本医療薬学会
雑誌: 医療薬学 (ISSN:1346342X)
巻号頁・発行日: vol.41, no.10, pp.714-721, 2015-10-10 (Released:2016-10-10)
参考文献数: 10
被引用文献数: 3 3

Seven products, currently on the market as acetaminophen suppository 100 mg, are commonly used for pyrexia in children, and yet there have been no reports on their solubility and divisibility. We examined the hourly solubility rate of each suppository using a dissolution tester for suppositories. In addition, we conducted a hardness test using the EZ-test, a questionnaire-based investigation on the accuracy and divisibility when the suppositories were divided. There was a significant difference between each suppository (P < 0.01). While 4 types dissolved completely within 60 minutes, one type took 120 minutes to dissolve completely. Another two had only 51 and 67%, respectively, at 180 minutes. The bases are hard fat in all suppositories. The types and additives of hard fat may have had an influence on solubility. The hardest suppository was assessed as showing marked differences in the weight ratio and solubility between the distal and tail portions when divided in half, due to which division was considered inappropriate, and there were differences in accuracy and divisibility among suppositories.From the above, it was suggested that the acetaminophen suppository 100 mg products may show differences in the solubility, time to action onset, and duration of the action. In addition, we should instruct physicians on important points of caution regarding the characteristics of each preparation when dividing the suppositories so that they can be given safely to infants.

2021-10-10 11:53:41
11 + 65 Twitter

4 0 0 0 OA クエン酸ナトリウムを用いて調製した魚肉加熱ゲルの摂取がラットの血圧および脂質濃度に及ぼす影響

著者: 桑原浩一井上舞安本早穂子鳥巣雄洋野口絵理香久保久美子田丸静香永田保夫田中一成
出版者: 公益社団法人日本水産学会
雑誌: 日本水産学会誌 (ISSN:00215392)
巻号頁・発行日: pp.17-00053, (Released:2018-01-30)
参考文献数: 24

食塩の代わりにクエン酸塩を用いて調製する魚肉の新たな加熱ゲル化方法を開発し,本方法で調製した加熱ゲルがラットの血圧や脂質濃度に及ぼす影響を検討した。新規または従来法で調製した加熱ゲルをAIN-76組成の食餌に添加した。新規加熱ゲルの摂取は,高血圧自然発症ラットの血圧上昇を抑制させた。また,調製方法に関わらず加熱ゲルの摂取は,血清コレステロールおよび肝臓トリグリセリド濃度を減少させ,肝臓の脂肪合成酵素活性を抑制させた。新規加熱ゲルは,血圧上昇抑制および脂質代謝改善作用を有することが明らかになった。

2023-03-04 03:26:43
4 + 7 Twitter

3 0 0 0 OA 動物病院カルテデータをもとにした日本の犬と猫の寿命と死亡原因分析

著者: 井上舞杉浦勝明
出版者: 公益社団法人日本獣医師会
雑誌: 日本獣医師会雑誌 (ISSN:04466454)
巻号頁・発行日: vol.75, no.6, pp.e128-e133, 2022 (Released:2022-06-15)
参考文献数: 8
被引用文献数: 1

犬や猫の死亡時年齢や死亡原因を把握することは,健康診断の設定や健康増進の対策を立てるうえで有用な情報となりうる.著者らは全国の40病院の協力を得て,2020年4月1日~2021年8月31日までの間に死亡した2,133頭の犬及び猫の死亡状況についてのデータを基にコホート生命表を作成したところ,犬の平均寿命は13.6歳,猫の平均寿命は12.3歳であった.犬の死亡原因は腫瘍が18.4%と最も多く,循環器疾患が次いで17.4%,続いて泌尿器疾患が15.2%であり,猫での死亡原因は多い順に泌尿器疾患が29.4%,腫瘍が20.3%,循環器疾患が11.8%であった.死亡原因として多い疾患の影響を除いた平均寿命を算出した所,犬の腫瘍では0.6歳,循環器疾患では0.5歳,猫の泌尿器疾患では1.6歳,腫瘍では1.0歳平均寿命が延びると推計された.このような研究をもとに優先順位をつけて疾患対策を行うことで効率的な健康増進が可能になると考えられる.

2022-09-26 08:23:35
3 + 1 Twitter

3 0 0 0 OA 家庭飼育犬における誤飲発生の実態に関する分析

著者: 島村麻子井上舞新井敏郎
出版者: 獣医疫学会
雑誌: 獣医疫学雑誌 (ISSN:13432583)
巻号頁・発行日: vol.16, no.1, pp.35-36, 2011-07-20 (Released:2013-01-04)
被引用文献数: 1 1

Veterinary clinicians often encounter with foreign body ingestion in domestic dogs. Accumulation of treatment information and epidemiological data about these cases could lead development of methods for prevention and enlightenment for dog owners. So far, these incidents are regarded as carelessness by dog owners, and veterinary clinicians did not show concrete directions for prevention of these incidents for owners. In this study, we analyzed animal health insurance claims data of these incidents in dogs and collected preventive findings about the cases from clinicians and owners using the internet research.Insurance claims data were used for analysis of the prevalence of these incidents in dogs. Total of 252,414 dogs which contracted Anicom animal health insurance from April 1 2009 to March 31 2010 were used as source data for analysis. 5,708 dogs cases were claimed as incidents caused by foreign body ingestion (total claims were 8,296 cases). Difference of prevalence of these incidents between ages is significant. 4.4% (2,728 dogs/61,448 dogs) for puppies under one year of age, 2.5% (736/29,215) for 1 year old, 1.8% (620/34,616) and under 1.5% for 3-10 years old. The average of prevalence for total dogs was 1.7%. Especially in puppies under one year of age, among top 17 breeds of insured dog, the prevalence of foreign body ingestion was 7.1% for French Bulldogs, 6.8% for Golden Retrievers, 6.0% for Cavalier King Charles Spaniels, 5.5% for Papillons, Labrador Retrievers, and 4.5% Toy Poodle. These breeds showed higher prevalence than the average (4.4%) for all breeds. For these breeds with higher prevalence materials/objects (substances) causing these incidents should be removed. The internet research with clinician prevailed that possible substances causing incidents (plural answer available) were some kinds of strings, seeds of fruit and plum pickles, medical supplies, pebble, grains of sand, some kinds of cloth like socks, towel and dust-cloth. Over 84% (145/172) clinicians reported that they encountered these incidents caused by above mentioned objects. Even 27 death cases were reported by strings, 16 cases by medical supplies and 13 cases by kinds of cloth. These objects/materials should be removed from dogs particularly. Death cases by accidental ingestions were also reported in dogs by poisoning of ornamental lily (12 cases), chocolate (9 cases) and onion (4 cases). The internet reserch for pet owners showed that over 90% of owners knew toxicity with chocolate and onion but only 29% of owners knew risk of poisoning with lily.Incidents caused by foreign body ingestion is very dangerous behavior inducing death in dogs, and careful monitoring of these incidents should be carried on with all concerned veterinary medicine.