1 0 0 0 アジ化ナトリウム集団中毒症例の検討
- 著者
- 広瀬 保夫 畑 耕治郎 本多 拓 山崎 芳彦 堀 寧 大関 暢
- 出版者
- 一般社団法人 日本救急医学会
- 雑誌
- 日本救急医学会雑誌 (ISSN:0915924X)
- 巻号頁・発行日
- vol.12, no.3, pp.125-129, 2001
- 被引用文献数
- 3
This report describes 7 victims of sodium azide poisoning caused by drinking poisoned water. Ten employees at the poisoning site developed symptoms immediately after ingesting coffee or tea made from hot water contained in a thermos bottle. Symptoms included altered consciousness, faintness, blackout, palpitation, nausea, and paresthesia of both hands and feet. Seven patients were transferred to our institution by ambulance. We assumed symptoms were caused by acute poisoning but the causative agent was unknown. We could not rule out cyanide poisoning because of the rapid emergence of symptoms suggesting circulatory failure, so we administered amyl nitrate, sodium nitrate, and sodium thiosulfate. Symptoms rapidly subsided. The causative agent was identified the next day as sodium azide. While the victims were being treated at the emergency room, 2 doctors, 3 nurses, and 1 pharmacist complained of faintness, headache, nausea, sensations of dyspnea and eye pain. These medical staff members had all either conducted gastric lavage or treated gastric contents. This strongly suggests that symptoms were caused by hydrazoic acid formed in a chemical reaction between sodium azide and gastric acid. Our experience underscores the potential hazard from hydrazoic acid faced by medical staff treating patients with oral sodium azide intoxication.
1 0 0 0 OA アジ化ナトリウム集団中毒症例の検討
- 著者
- 広瀬 保夫 畑 耕治郎 本多 拓 山崎 芳彦 堀 寧 大関 暢
- 出版者
- Japanese Association for Acute Medicine
- 雑誌
- 日本救急医学会雑誌 (ISSN:0915924X)
- 巻号頁・発行日
- vol.12, no.3, pp.125-129, 2001-03-15 (Released:2009-03-27)
- 参考文献数
- 9
- 被引用文献数
- 1 3
This report describes 7 victims of sodium azide poisoning caused by drinking poisoned water. Ten employees at the poisoning site developed symptoms immediately after ingesting coffee or tea made from hot water contained in a thermos bottle. Symptoms included altered consciousness, faintness, blackout, palpitation, nausea, and paresthesia of both hands and feet. Seven patients were transferred to our institution by ambulance. We assumed symptoms were caused by acute poisoning but the causative agent was unknown. We could not rule out cyanide poisoning because of the rapid emergence of symptoms suggesting circulatory failure, so we administered amyl nitrate, sodium nitrate, and sodium thiosulfate. Symptoms rapidly subsided. The causative agent was identified the next day as sodium azide. While the victims were being treated at the emergency room, 2 doctors, 3 nurses, and 1 pharmacist complained of faintness, headache, nausea, sensations of dyspnea and eye pain. These medical staff members had all either conducted gastric lavage or treated gastric contents. This strongly suggests that symptoms were caused by hydrazoic acid formed in a chemical reaction between sodium azide and gastric acid. Our experience underscores the potential hazard from hydrazoic acid faced by medical staff treating patients with oral sodium azide intoxication.
1 0 0 0 OA IABPの腎血行動態に及ぼす影響とくに腎血流と交感神経トーヌスの関係
- 著者
- 諸 久永 富樫 賢一 土田 昌一 藤田 康雄 小管 敏夫 大関 一 林 純一 斉藤 憲 山崎 芳彦 江口 昭治
- 出版者
- 一般社団法人 日本人工臓器学会
- 雑誌
- 人工臓器 (ISSN:03000818)
- 巻号頁・発行日
- vol.18, no.2, pp.507-510, 1989-04-15 (Released:2011-10-07)
- 参考文献数
- 10
IABPの腎血行動態に及ぼす効果について、腎交感神経切除を施行して、腎血流と腎交感神経トーヌスの関係を中心に、検討した。雑種成犬10頭を用い、熱希釈法にて腎血流量、心拍出量を測定し、腎血流量分配率、腎血管抵抗および末梢血管抵抗を算出し、次の結果を得た。1. IABP作動時の腎血流量の増加は、主として腎血管抵抗の低下によりもたらされた。2. denervation後では、IABP作動の有無に拘らず、腎血管抵抗は低値を維持し、腎血流量は変化しなかった。3. 腎血管抵抗は交感神経トーヌスにより影響されているが、IABPは、かかる交感神経支配下でも、血管抵抗の低下をもたらした。
