著者

前田 雅子 前田 稔彦 松元 加奈 森田 邦彦

出版者

一般社団法人 日本プライマリ・ケア連合学会

雑誌

日本プライマリ・ケア連合学会誌 (ISSN:21852928)

巻号頁・発行日

vol.38, no.4, pp.335-339, 2015 (Released:2015-12-25)

参考文献数

11

被引用文献数

3

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目的 : 診療時グラム染色検査の導入が抗菌薬の使用動向に影響を及ぼすかを検討することを目的とした.方法 : グラム染色導入前後での抗菌薬の種類・使用量の動向, 診療経過の動向を後方視的に調査した.結果 : 抗菌薬処方頻度 (100 人当たり) は, マクロライド系は20.9件 (2006年) から3.6件 (2012年) , 第三世代セフェム系は7.9件 (2005年) から2.4件 (2012年) に減少の一方, ペニシリン系は1.6件から3.9件に増加した. それにともなって1人当たりの抗菌薬消費額が約1/5に低下した. 小児急性副鼻腔炎患者50人当たりの抗菌薬不使用患者数は9倍に増加した一方, 治療期間中に抗菌薬2種類以上を処方された患者数は26名から9名に減少し, 治癒に要した日数は約6日間短縮された.結論 : グラム染色導入がよりよい抗菌薬使用につながる取り組みとなる可能性が示唆された. 多施設での研究的取り組みによる評価の必要性が考慮される.

著者

三木 芳晃 塚本 啓介 奥村 裕英 半崎 隼人 安井 良則 松元 加奈 森田 邦彦 萱野 勇一郎

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.44, no.7, pp.349-354, 2018-07-10 (Released:2019-07-10)

参考文献数

4

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There are few reports regarding the optimal decomposition condition of the antimicrobial agent. We therefore conducted a questionnaire about the decomposition operation of the antimicrobial agent vial preparation for nurses in Osaka Saiseikai Nakatsu Hospital. Furthermore, the optimal dissolution conditions for “Zosyn ® IV for intravenous injection 4.5 (tazobactam/piperacillin; TAZ/PIPC)” were examined. As a result of the questionnaire survey, most nurses selected a syringe of 10 mL for formulations that are easy to dissolve while, for difficult to dissolve formulations, answers were split between 10 mL and 20 mL. The shaking time of vials ranged from under 5 seconds to under 30 seconds for the soluble formulations and from under 5 seconds to more than 1 minute for the difficult to dissolve formulations. We set each decomposition condition from the questionnaire results and examined the optimal condition, which accorded with the clinical settings in the decomposition operation of TAZ/PIPC. As a result of having examined the decomposition condition from the absorbance of each complete decomposition preparation of TAZ/PIPC, it was found that more than 93% of dissolution was carried out with the injection of saline at 15 mL and the shaking time of 10 or 20 seconds, or the injection of saline at 20 mL and the shaking time of 10 seconds. If the injection volume and the shaking time are less than these conditions, residual drugs are found in the vials.

著者

長井 紀乃 島 正吾 森田 邦彦 栗田 秀樹 吉田 勉 鵜飼 弥英子 森 紀樹 荒川 友代 谷脇 弘茂

出版者

The Japanese Society for Hygiene

雑誌

日本衛生学雑誌 (ISSN:00215082)

巻号頁・発行日

vol.44, no.5, pp.1014-1020, 1989-12-15 (Released:2009-02-17)

参考文献数

15

被引用文献数

3 3

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The effects of cobalt (Co) and nickel (Ni) on the humoral immune response were studied by two indexes of specific IgM antibody production against sheep red blood cells (SRBC) and polyclonal IgG antibody production in the spleens of mice intraperitoneally injected with cobalt chloride or nickel chloride.An experiment for the effect of both metals on specific IgM production was carried out by measuring IgM plaque-forming cells in the spleens of mice intraperitoneally injected with both metal salts using 1/10, 1/100 or 1/200 of LD50 for i. p. injection three times every other day and were immunized with SRBC on the day of the last injection of each metal salt. The other experiment for the effect of both metals on polyclonal IgG production was done by measuring, on days +3 or +6 in relation to the last injection of metal salts, polyclonal IgG-forming cells in the spleens of mice injected with both metal salts using 1/10 or 1/100 of LD50 for i. p. injection three times every other day by the reverse plaque-forming method.The following results may be drawn from this study:1. Co may cause changes in the homeostasis of humoral immune response even more than affecting the immune system with immunotoxicity as antigenicity.2. On the other hand, Ni may have antigenicity even more than an acting as immunomodulator influencing the immune system.

著者

松元加奈 森田邦彦[著]

出版者

中外医学社

巻号頁・発行日

2020

著者

矢野 育子 井関 健 東海林 徹 青山 隆夫 木津 純子 中村 均 藤井 俊志 渡邊 美智留 野田 幸裕 脇屋 義文 森田 邦彦 手嶋 大輔 二神 幸次郎

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.35, no.1, pp.43-49, 2009 (Released:2010-02-07)

参考文献数

8

被引用文献数

1 1

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With the introduction of 6-year pharmacy educational program in 2006,a provision was made to assign pharmacist faculties having working experience as pharmacists in pharmacy schools.In October 2007,we conducted a survey to investigate the situation of pharmacist faculties.We sent a questionnaire to 247 pharmacist faculties in 66 pharmacy schools and the response rate was 84.9%.The faculties consisted of professors (43%),associate professors (23%) and lecturers (23%),and 77% of them had a Ph.D.degree.In a typical week,the major activities they engaged in were educational activities (20.6 hrs),research (12.2 hrs) and management (9.6 hrs).While the average time they were occupied by clinical practice was 3.5 hrs,67% of them did not do any.Half of the faculties did not conduct any research with students or graduate students in their own schools,and in 2007 only 55% applied for Grant-in-aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology of Japan.Twenty-six percent said they were very satisfied or satisfied with their work on a five-point scale,and 44% rated their degree of satisfaction as fair.In conclusion,our survey showed that most pharmacy faculties are not sufficiently engaged in clinical practice and do not spend much time in clinical research.We hope that its results will promote discussions among pharmacy personnel concerning the role of pharmacist faculties so that even better clinical pharmacy education may be provided to students in pharmacy schools.

著者

山内 真里奈 西端 麻莉 松元 加奈 本田 順一 森田 邦彦

出版者

日本医療薬学会

雑誌

日本医療薬学会年会講演要旨集

巻号頁・発行日

vol.20, 2010-10-25