著者
米田 一路 齋藤 美樹 西山 正晃 植木 洋 坂上 亜希恵 渡部 徹
出版者
公益社団法人 土木学会
雑誌
土木学会論文集G(環境) (ISSN:21856648)
巻号頁・発行日
vol.78, no.7, pp.III_23-III_32, 2022 (Released:2023-03-10)
参考文献数
35

牡蠣を人為的にノロウイルスGII.2とGII.4に汚染する実験を行い,牡蠣に蓄積されたノロウイルス量の分析を行った.ノロウイルスGII.2(陽性率:80.0%)はGII.4(陽性率:60.0%)よりも牡蠣に蓄積されやすい傾向があった.遺伝子型に関わらず,高濃度のノロウイルスGIIを添加した人工海水で24時間飼育しても,ノロウイルスGIIを蓄積しない牡蠣が存在し,ウイルス蓄積量の多い牡蠣(中腸腺1g当たり約4.08log copies)と少ない牡蠣では100倍以上の個体差があったが,牡蠣のノロウイルスGII蓄積量は,個体重量や中腸腺重量とは相関がなかった.今回の実験で確認されたようなウイルス蓄積量の少ない牡蠣を選別して養殖できれば,より安全性の高い牡蠣の提供につながるだろう.
著者
林清 五郎 植木 寛 植木 洋子
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.54, no.4, pp.381-390, 1963-12-31 (Released:2008-10-23)
参考文献数
14

The antitumor activities of 4, 5-bis(ethyleneimino)-1, 2-benzoquinone (OBE), 2, 5-bis(ethyleneimino)-1, 4-benzoquinone (PBE), and 4-ethyleneimino-1, 2-naphthoquinone (NQE) were investigated in Ehrlich carcinoma. OBE was effective not only in prolonging the life-span of mice bearing Ehrlich ascites carcinoma but also in retarding the growth of the solid form of the same tumor. This compound was proved to be effective even in a smaller dose than the minimum effective dose of PBE, with lower toxicity than the latter. With NQE, the mice bearing the same ascites tumor did not survive longer than the control.Ratio of the number of neutrophils to lymphocytes (N/L) in the peripheral blood was compared with the non-treated and the treated groups of animal bearing the tumor. Generally speaking, the more progressed the growth of the ascites tumor was, the greater the value of N/L, but such increase of N/L was eventually observed in case of leucopenia induced by these agents. It may therefore be said that the observation of change of N/L should be considered as an element for evaluation of the result of screening experiment.
著者
植木 洋輔
出版者
一般社団法人 日本機械学会
雑誌
日本機械学会論文集 (ISSN:21879761)
巻号頁・発行日
vol.81, no.821, pp.14-00225, 2015 (Released:2015-01-25)
参考文献数
7
被引用文献数
1

The objective of this study is to establish a methodology for high-speed fatigue testing, especially for resin materials, which includes fiber reinforced composites. To exert periodic stress on a material at a frequency of more than 200 Hz, a specimen was fixed as a cantilever to an electromagnetic vibrator and vibrated in its resonant frequency of the 1st bending mode by using a resonance tracking control. The shape of a specimen made of glass fiber-epoxy laminate was designed with finite element vibration analysis to obtain a resonant frequency of more than 200 Hz and a desired strain distribution for inducing fatigue damage under a certain stress level. A rise of temperature during the fatigue testing due to damping loss was estimated with a heat transfer theory and suppressed by external cooling to keep the specimen at a normal temperature. To confirm the validity of the high-speed testing, a completely reversed bending test at 1 Hz with identical specimens was also performed. Results both from testing at 230 Hz and 1 Hz were plotted on a single power-law curve in an S-N plot, which is a well-known fitting for fiber reinforced composites. This result suggests that we can evaluate fatigue strength in the high- or giga-cycle region for resin and composites in a very short time if temperature is controlled appropriately.