著者

池田 克巳 引間 徹 楠 公仁 渡辺 幸男 藤橋 弘 日吉 貴一郎 菅沼 信夫 岩崎 浩一郎

出版者

特定非営利活動法人 日本歯周病学会

雑誌

日本歯周病学会会誌 (ISSN:03850110)

巻号頁・発行日

vol.23, no.3, pp.437-450, 1981-09-28 (Released:2010-07-16)

参考文献数

32

被引用文献数

3 3

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In order to prevent the periodontal disease, it would be a matter of important fact to apply cleaning the teeth and giving massage on marginal gingiva by means of brushing and using dentifrices including effective ingredients.The aim of this study was to investigate on the effects of the dentifrice including tranexamic acid (T dentifrice) comparing with placebo (P dentifrice).Subjects were 242 students of Josai Dental University who had no serious oral disease.P-M-A index, redness, bleeding and dental plaque were selected as indices for clinical evaluation of periodontal disease. This study was conducted with double blind method.The results obtained were as follows:1) Subjects used for statistical analysis were 207 students. (104: T dentifrice group, 103: P dentifrice group).2) T dentifrice was significantly more superior in recovery of P-M-A index (p<0.01), redness (p<0.01) and bleeding (p<0.05). On the other hand, there was no significant difference in recovery of dental plaque between T dentifrice and P dentifrice.3) The mean reduction rates of T dentifrice and P dentifrice were 31.0% and 14.3% in P-M-A index, 36.3% and 19.6% in redness, 66.7% and 42.9% in bleeding, respectively.4) Significant difference was observed in the general improvement (p<0.01). The rates of the general improvement of T dentifrice and P dentifrice were 71.0% and 48.5%, respectively.5) No particular side effect was observed through this study.

著者

伊藤 弘 仲谷 寛 沼部 幸博 鴨井 久一 辰已 順一 栗原 徳善 渡辺 幸男 池田 克已

出版者

特定非営利活動法人 日本歯周病学会

雑誌

日本歯周病学会会誌 (ISSN:03850110)

巻号頁・発行日

vol.35, no.2, pp.417-428, 1993-06-28 (Released:2010-08-25)

参考文献数

36

被引用文献数

2 1

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本研究の目的は, 垂直性骨欠損においてコラーゲンより精製した吸収性膜を組織再生誘導法 (GTR法) に応用し, 臨床的な評価を検索することである。慢性辺縁性歯周炎と診断され, 歯周初期治療終了後, 外科処置の必要性がある垂直性骨欠損を有する31名の患者に対してGTR法を応用した。GTR法は通常のフラップ手術に準じて行った。すなわち, 粘膜骨膜弁にて剥離, 翻転した後, 骨欠損部にコラーゲン膜を完全に覆うように調整し, 歯肉弁を復位し縫合を行った。術後3カ月, 6カ月に各々臨床評価を行った。その結果, 術後3カ月では術前と比較して骨変化量は, 1.15mmの増加, 付着の獲得量は, 1.52±1.81mmの増加, また, ボケットの深さは2.75±1.54mmの減少を認めた。術後6カ月では術前と比較して骨変化量は, 1 . 26mmの増加, 付着の獲得量は, 1.68±1.75mmの増加, また, ポケットの深さは2.84±1.54mmの減少を認めた。以上の結果より, 歯周組織の再生を目的としたGTR法におけるコラーゲン膜の応用は有用な処置方法であることが示唆された。

著者

江藤 正信 落合 美和子 渡辺 幸男

出版者

日本養豚学会

雑誌

日本養豚研究会誌 (ISSN:03888460)

巻号頁・発行日

vol.16, no.2, pp.155-157, 1979-09-30 (Released:2011-06-08)

参考文献数

5

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PPVはきわめて抵抗性の強いウィルスである。その不活化は73゜30分間, 70゜1時間の熱作用により行なわれた。化学的薬剤に対しては, 次亜塩素酸ナトリウム液0.5%, ジクロールイソシアヌール酸カリウム0.06%5分間およびホルマリン3%1時間作用により不活化され, 有効であった。

著者

石原 勝也 菅沼 保治 渡辺 幸男

出版者

社団法人日本獣医学会

雑誌

日本獸醫學雜誌 (ISSN:00215295)

巻号頁・発行日

vol.39, no.2, pp.149-157, 1977-04-25

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The present studies were undertaken to obtain data on serum lipoprotein analysis which would serve as normal references for studies on serum lipoproteins in diseased dogs, especially those with canine dirofilariasis. Serum samples were collected from 35 normal dogs of various ages proved to be free from Dirofilaria immitis (filaria) by the routine physical checkup and laboratory examination. They were analyzed for lipoproteins by cellulose acetate electrophoresis (electrophoresis). The serum lipoproteins were obtained basically as four distinct fractions, i.e., α-, pre-β-, β-lipoprotein and chylomicron fractions. The last-named fraction was only in trace quantities. It was presumed that the four fractions might have a density of 1.063<1.210, 1.006<1.019, 1.019<1.063 and <1.006, resptctively, as estimated from the electromigration velocities (mobilities) of other samples which had been separated ultracentrifugally. The mobility of the pre-β-lipoprotein fraction, however, varied with the serum sample, possibly due to the difference in the quantity of lipids bound to this fraction of serum lipoproteins. On the basis of analytical data on the 35 normal dogs, the normal percentage composition (relative proportion) of the serum lipoprotein fractions was investigated in dogs. Furthermore, the concentrations of these fractions in the serum were calculated from data on the total serum lipid content, the percentage composition of the serum lipoprotein fractions, and the amounts of lipids bound to the lipoprotein fractions obtained from 25 of the 35 dogs in order to clarify the normal ranges.