著者

Hiroyuki Tsugita Maho Aoyama Noriaki Satake Makoto Saito Yusuke Hiratsuka Akira Inoue Shin Takayama Mitsunori Miyashita

出版者

Tohoku University Medical Press

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.254, no.3, pp.155-161, 2021 (Released:2021-07-03)

参考文献数

20

被引用文献数

2

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Management of nausea is an important dimension of palliative care. The first choice for treating nausea is antiemetics, but their efficacy is inadequate. Acupressure intervention for nausea in cancer patients has been studied as a non-pharmacological therapy, and appears to have had some effect. However, such a therapy has not been well reviewed in patients with terminal cancer. The purpose of this study was to clarify the feasibility of acupressure intervention and examine its safety and preliminary efficacy. We recruited cancer patients that fulfilled the eligibility criteria and were admitted to the palliative care unit, from August 2018 to February 2019, in Tohoku University Hospital, Japan. We conducted a longitudinal assessment of acupressure intervention in a single arm. We identified the patient’s research accomplishments and evaluated possible fainting due to the vagal reflex and symptom severity. Descriptive statistics were used to calculate the completion rate for the feasibility and Wilcoxon signed-rank tests to compare the average of continuous variables for the safety and efficacy. Twelve patients participated in this study and completed the procedure. Their average age was 70 years (SD = 9.3), and the most common primary cancer sites were the rectum and pancreas. The blood pressure and pulse rate did not drop sharply. Four patients exhibited decreased nausea but there was no statistically significant difference (P = 0.5). We suggested that acupressure has high feasibility and safety, as an intervention for patients with terminal cancer. However, no significant differences were observed regarding its effect on nausea.

著者

Hiroshi Takagi Akihiko Ito Heon-Sook Kim Shamil Maksyutov Makoto Saito Tsuneo Matsunaga

出版者

Meteorological Society of Japan

雑誌

SOLA (ISSN:13496476)

巻号頁・発行日

vol.17, pp.213-219, 2021 (Released:2021-12-14)

参考文献数

45

被引用文献数

2

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Numerous wetlands, including the world's two largest contiguous wetlands, lie along the free-flowing Paraná and Paraguay Rivers that travel the length of subtropical South America (SSA) region. These wetlands are floodplains that are inundated with rising river water in flood events; their morphology and area are highly changeable with flooding extent. The long-term variability of methane emission from this wetland hotspot and its sensitivity to meteorological conditions are not well known. We herein explore this unknown using space-based estimates of methane flux for the SSA region between 2009 and 2015 along with data of water balance. We find that methane emission from this region coherently varies with precipitation and inundation areal extent.

著者

Etsuro MORI Masatsune ISHIKAWA Takeo KATO Hiroaki KAZUI Hiroji MIYAKE Masakazu MIYAJIMA Madoka NAKAJIMA Masaaki HASHIMOTO Nagato KURIYAMA Takahiko TOKUDA Kazunari ISHII Mitsunobu KAIJIMA Yoshihumi HIRATA Makoto SAITO Hajime ARAI

出版者

The Japan Neurosurgical Society

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

vol.52, no.11, pp.775-809, 2012 (Released:2012-11-25)

参考文献数

253

被引用文献数

149 478

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Among the various disorders manifesting dementia, gait disturbance, and urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus (iNPH) is becoming of great importance. After the publication of the first edition of the Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus in 2004 (the English version was published in 2008), clinical awareness of iNPH has risen dramatically, and the number of shunt surgeries has increased rapidly across Japan. Clinical and basic research on iNPH has increased significantly, and more high-level evidence has since been generated. The second edition of the Japanese Guidelines was thus published in July 2011, to provide a series of timely evidence-based recommendations related to iNPH. The revision of the Guidelines has been undertaken by a multidisciplinary expert working group of the Japanese Society of Normal Pressure Hydrocephalus in conjunction with the Japanese Ministry of Health, Labour and Welfare research project on “Studies on the epidemiology, pathophysiology, and treatment of normal pressure hydrocephalus.” This English version of the second edition of the Guidelines was made to share these ideas with the international community and to promote international research on iNPH.

著者

Hiroshi Takagi Akihiko Ito Heon-Sook Kim Shamil Maksyutov Makoto Saito Tsuneo Matsunaga

出版者

Meteorological Society of Japan

雑誌

SOLA (ISSN:13496476)

巻号頁・発行日

pp.2021-037, (Released:2021-10-13)

被引用文献数

2

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Numerous wetlands, including the world's two largest contiguous wetlands, lie along the free-flowing Paraná and Paraguay Rivers that travel the length of subtropical South America (SSA) region. These wetlands are floodplains that are inundated with rising river water in flood events; their morphology and area are highly changeable with flooding extent. The long-term variability of methane emission from this wetland hotspot and its sensitivity to meteorological conditions are not well known. We herein explore this unknown using space-based estimates of methane flux for SSA region between 2009 and 2015 along with data of water balance. We find that methane emission from this region coherently varies with precipitation and inundation areal extent.

著者

Katsuhiro Asamatsu Kai Yoshitake Makoto Saito Wipoo Prasitwuttisak Jun-ichiro Ishibashi Akihi Tsutsumi Nurul Asyifah Mustapha Toshinari Maeda Katsunori Yanagawa

出版者

Japanese Society of Microbial Ecology / Japanese Society of Soil Microbiology / Taiwan Society of Microbial Ecology / Japanese Society of Plant Microbe Interactions / Japanese Society for Extremophiles

雑誌

Microbes and Environments (ISSN:13426311)

巻号頁・発行日

vol.36, no.4, pp.ME21048, 2021 (Released:2021-11-25)

参考文献数

71

被引用文献数

1

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A novel deep-branching archaeal lineage was discovered at high-temperature hot springs around Oyasukyo Gorge in Akita Prefecture, Japan. Actively boiling hot spring water contained >1×104 microbes mL–1. The microbial community composition assessed by analyzing 16S rRNA gene amplicons revealed that the dominant bacterial phyla were Proteobacteria and Aquificae (>50% of the microbial composition) in samples collected in 2016 and 2019, respectively. Approximately 10% of the reads obtained in both years were not assigned to any taxonomy. The more detailed phylogenetic positions of the unassigned sequences identified using a clone library and phylogenetic tree showed that they formed a clade that was independent, distantly related to known phyla, and had low similarity (<82%) to all other sequences in available databases. The present results suggest that this novel archaeal phylum-level lineage thrives in boiling hot springs in Japan.

著者

TAKESHI AMEMIYA MAKOTO SAITO KEIKO SHIMONO

出版者

JAPANESE ECONOMIC ASSOCIATION

雑誌

The Economic Studies Quarterly (ISSN:0557109X)

巻号頁・発行日

vol.44, no.1, pp.13-28, 1993-03-19 (Released:2008-02-28)

参考文献数

6

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In this paper we analyze the investment patterns of Japanese households using three kinds of generalized Tobit models. We consider the following three types of investments: (1) bank deposits, (2) long-term income-gain assets, and (3) capital-gain assets. Generalized Tobit models are called for because there are households which do not possess either or both of the last two types of assets. In our data every household does possess the first type of asset, and this fact will be incorporated into our models as a priori specification. The three models we estimate are a simultaneous equations Tobit model, a Dubin-McFadden type model, and a sequential Tobit model. The first model arises from a Kuhn-Tucker solution to the maximization of a quadratic utility function subject to the constraint that the sum of the investments into the three types of assets is equal to an exogenously-determined value of the total assets of a household. The second model is based on the assumption that there are fixed costs of owning the last two types of assets. Finally, the last model is derived from the assumption that a household first determines the amount of the first type of asset it should hold and second allocates whatever left into the other two types of assets. Simpler, more obvious ways to analyze our data are available, such as ordinary least squares, probit and logit, and standard Tobit. These estimates are also reported and compared with our elaborate estimates in a later section.

著者

尾田 十八 / 齊藤 誠 Makoto SAITO

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集 A編 (ISSN:03875008)

巻号頁・発行日

vol.67, no.653, pp.121-126, 2001-01-25 (Released:2008-02-21)

参考文献数

8

被引用文献数

4 3

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Lsystem (LS) is a technique expressing a formation algorithm creating the various shape patterns by the simple rules. Using LS, the complex branch phenomena of plants could be described by simple rules. This paper has tried the methodology to apply LS to the structural design. This methodology grows up the structure as if plants grow up, and produces the optimum structure that is appropiate for the design purpose. It is difficult to acquire LS rules for the optimum structure because the rules have many degrees of freedom. Therefore, this paper proposes an idea that evolves LS rules using Genetic Algorithms (GA) . The methodology is called as an evolutionary LS (ELS) . Using the methodology, the design problems to decide optimum distribution of material and plate thickness are solved.