著者

今橋 鐵三

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.40, no.12, pp.2451-2464, 1928

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Es wurde der Einfluss verschiedener Mittel auf die zum Tode führende Tetrodotoxinvergiftung bei der Maus untersucht, indem man dem Tiere diese Mittel mit der letalen Dosis von Tetrodotoxin gleichzeitig subkutan einführte. Die Versuche erstreckten sich einerseits auf die vorwiegend zentral erregenden, andrerseits auf die die peripheren motorischen Apparate erregenden Gifte und ferner auf die Substanzen mit keiner spezifischen Wirkung, wie Traubenzucker und Alkalien, welch letztere in vitro das betreffende Gift entgiften sollen. Die Ergebnisse sind, wie folgt, kurz zusammenzufassen. 1. Pikrotoxin, Physostigmin, Guanidin und Adrenalin beeinflussen nicht nur den Tetrodotoxintod antagonistisch, sondern verstärken auch die Toxizität. 2. Kaffein, Hexeton und Coramin wirken der Vergiftung entgegen, indem sie die Lebensdauer der Tiere mässig zu verlängern vermögen. Cardiazol und Traubenzucker sind auch wirksam, scheinen aber diesen genannten etwas nachzustehen. 3. Lobelin und Natriumkarbonat zeigen einen viel günstigeren Erfolg, denn sie verlängern nicht nur die Lebensdauer, sondern vermindern auch die Mortalität der vergifteten Tiere. Besonders ist Natriumkarbonat am stärksten wirksam. Daraus geht hervor, dass bei der tödlichen Vergiftung durch Fugugift die atmungserregenden Mitiel mit mehr Erfolg lebensrettend sind, als die Mittel, welche auf die peripheren motorischen Apparate erregend wirken, und dass Alkalien, die das Gift chemisch zerstören können, den besten Erfolg haben.

著者

高樹 正浩

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.1, pp.79-94, 1959-12-30

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In order to elucidate the stability of the occured change on the properties of the tsutsugamushi disease rickettsia by contineous action of small amount of chloramphenicol in the body of mouse, the author investigated the stability of the varied rickettsia using that rickettsia as the antigen in the complement fixation test. As the result of this investigation, the occured change on the properties of the rickettsia found to be turned back to that of the original rickettsia by serial passage through normal mouse at least 7 generations.

著者

Takahashi Yoshio

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.38, no.437, pp.611-632, 1926-06-30

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炭類ガ著明ナル吸着作用ヲ有スルコトハ甚ダ舊キ時代ヨリ知ラレタル事實ニシテ, 之レガ治療的應用ハ既ニ埃及時代ヨリ試ミラレタルガ如シ. 而シテ炭類ノ吸着作用ニ就テ, 科學的ニ藥物學的研究ヲ行ヒタルハWichowskiヲ以テ嚆矢トナス. 輓近丹村氏ハ血炭及ビ木炭ノ毒物吸着ニ關スル生物學的研究ヲ發表セリ. 余ハ摘出家兎腸管, 子宮及ビ蛙心ニ於テ, 骨炭ノ外, 白陶土, 滑石, 硫酸「バリウム」及ビ「アラビアゴム」ヲ吸着相トシ, 種々ノ毒物吸着作用ニ關スル生物學的研究ヲ行ヒ, 大要次ノ如キ結論ヲ得タリ. 物理學上吸着相トシテ知ラレタル骨炭, 白陶土, 滑石, 硫酸「バリウム」及ビ「アラビアゴム」ハ生物學的實驗ニ於テモ亦其吸着現象ニヨリ解毒作用ヲ呈スルヲ認メ, 且夫等吸着相ノ諸種毒物ニ對スル吸着ノ量的關係ヲ明ラカニスルコトヲ得タリ. 如上ノ諸吸着相ハ, 毒物ノ營養液中ニ溶解セルモノハ勿論, 既ニ臟器組織内ニ侵入セルモノヲモ尚良ク吸着脱取シテ其作用ヲ消失セシム. 而シテ其際吸着セラレ得ベキ毒物最大量ハ兩者ノ場合ニ於テ殆ンド差異ヲ呈セズ. 各吸着相ノ吸着能力ヲ比較スルニ, 骨炭ハ其力最モ顯著ニシテ白陶土, 滑石及ビ「アラビアゴム」ハ其力著シク劣リ, 硫酸「バリウム」ニ至リテハ其力微弱ニシテ骨炭ト比較ス可クモアラズ. 同一吸着相ニ吸着セラルル毒物ノ量ハ, 其種類ニヨリテ大差アルヲ認メタリ. 余ノ實驗成績ニ據レバ一定量ノ吸着相ニ吸着セラルル毒物量ハ, 濃度ヲ増スニ從ツテ比較的減少スルヲ見タリ. 之ハ物理學的實驗ト全ク一致スル所ナルガ, 例外トシテ「ビロカルビン」及ビ「ストロフアンチン」ハ之レニ反シテ濃度ヲ増セバ被吸着量ハ吸着相増加トノ比例以上ニ増加スルヲ認メタリ. 本實驗ニ於テ吸着作用ハ頗ル迅速ニ起ルヲ見, Freundlichノ凡テ吸着現象ハ極メテ迅速ニ現ハレ數秒ニシテ一定ノ平衡状態ニ達ス, ト云ヘル事實ニ一致スルヲ認メタリ. 即チ營養液中ニ第一次吸着相ヲ, 第二次毒物ヲ注加スルトキハ, 毒物ハ直チニ吸着セラレテ其作用ハ全ク表ハレザルカ, 或ハ現ハルルモ甚ダ微弱ニシテ直チニ正常ニ恢復スルヲ見ル. 之レニ反シ, 第一次毒物ヲ注加シ其作用ヲ臟器ニ及ボシタル後, 第二次吸着相ヲ加ヘ其毒物ヲ吸着脱取セシメテ臟器ノ官能ヲ恢復セシムルニハ, 毒物ノ種類ニヨリテ著シク時間的差異アルヲ見ル. 「ビロカルビン」「アドレナリン」及ビ「コカイン」等ニ對シテハ容易ニ其官能ヲ恢復セシメ得ルモ, 「ストロフアンチン」ノ如キ「デイギタリス」屬ノ通有性トシテ組織ト堅ク結合スル毒物ニ對シテハ, 臟器ノ官能ヲ恢復セシムルニ甚ダ長時間ヲ要スルヲ認メタリ. 實驗方法トシテ, 吸着相ノ器底ニ沈滯スルヲ防ギ可及的平等ニ營養液中ニ浮遊セシメンガ爲四本ノ通氣嘴管ト一個ノ攪拌器トヲ設ケタルガ, 甚好成績ヲ收メ得タリ. 上述各吸着相特ニ骨炭ノ如キ吸着作用顯著ナルモノハ, 解毒ヲ目的トスル治療的應用ニ向ツテ効果確實ナル可キハ勿論ナレドモ, 爾他ノ吸着相ノ如キ吸着能力比較的微弱ナルモノト雖モ, 之レヲ他ノ藥物ト併用スルニ際シテハ, 其作用ヲ減弱乃至遲延セシムル虞アルハ實地上看過ス可カラザル事實ナリト云フ可シ.

著者

小野 吉昭

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.68, no.10, pp.1821-1837, 1956-10-31 (Released:2009-03-30)

参考文献数

58

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“Umayado Disease” has happened in summer especially at east area of Kagawa-ken.I have studied about. what kind of Tsutsugamushi will have increased and made peak at summer.Against this purpose, I have caught rats and collected the Tsutsugamushi living upon the rats twice a month regularly extending full 2 years up, and I have determined that a lot of Trombicula tosa has appeared and made the peak at summer usually.I think Trombicula tosa should be valuable agency to contaminate the Rickettsia orientalis at Kagawa-ken.

著者

吉岡 明彦

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.120, no.3, pp.285-289, 2008-12-01 (Released:2009-01-05)

参考文献数

21

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Objective: To examine the specificity of QuantiFERON®TB-2G (QFT) in tuberculosis contact investigations of children. Methods: A schoolgirl was diagnosed with smear-positive pulmonary tuberculosis. To determine the extent of tuberculosis infection among contact schoolchildren, tuberculin skin tests were performed on 75 children enrolled in the school. All the children had been vaccinated with BCG at least once. The QFT test was then given to the 68 children who had tuberculin reactions including erythema larger than 10mm in diameter. Written informed consent was obtained from a parent of each child. Results: The number of infected subjects was 22 based on tuberculin skin test results. Of the 68 contacts, 1 was positive for QFT, 2 were doubtful positive, and the remaining 65 were negative. During the 2-year follow-up, none of the children developed tuberculosis. Specificity was 95.6%. Conclusions: It was confirmed that the additional use of QFT would reduce the number of indications for chemoprophylaxis cases. The current criteria for the indication of chemoprophylaxis based on a strong tuberculin reaction are considered unreliable, causing many subjects with strong reactions to be given unnecessary preventive medications.

著者

板谷 裕子

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.116, no.1, pp.29-38, 2004-05-31 (Released:2011-06-03)

参考文献数

48

著者

万倉 三正 野田 泰子 森 昭胤

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.124, no.1, pp.15-26, 2012-04-02 (Released:2012-04-29)

参考文献数

61

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Diabetes mellitus (DM) represents a global health and economical problem. Many patients with DM in Asia, South America, India and East Africa have traditionally used the water extract of unripe fruits of Momordica charantia (bitter melon) as some form of complementary and alternative medicine. Studies of laboratory animals have shown the beneficial blood-glucose lowering and anti-diabetic effects of this remedy. Some oral components that bring lower blood glucose level have been isolated : charantin (sterol glycosides), charantin (polypeptide) and cucurbine-type triterpenes. Part of their actions are related to AMP-activated kinase and repression of the oxidative stress that is increased in DM. Most clinical reports are not fully convincing due to the lack of randomized control studies. The present article reviews the pharmacological and clinical effects of bitter melon with special emphasis on the anti-diabetic effects, and some effects that would require caution in the context of human trials.

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.31, no.348, pp.41-41, 1919 (Released:2009-08-24)

著者

吉井 清水

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.63, no.2, pp.56-58, 1951-03-31 (Released:2009-05-26)

参考文献数

6

被引用文献数

1

著者

高塚 住子

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.82, no.9, pp.431-434, 1970-10

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In order to know the relationship between concentration of trichloroethylne and the amount of urinary trichloroethanol or trichloroacetic acid, average concentration of trichloroethylene inhaled by the workers in an automobile parts factory was measured by Kitagawa detector tube at 20-minute's interval. And urinary trichloroethanol and trichloroacetic acid were determined by Ikeda's oxidation method of chromium trioxide and our direct colorimetricmethod. The results were as follows. 1. Straight relationship between trichloroethylene concentration in the air and trichloroethanol or trichloroacetic acid in the urine was recognized by Ikeda's method. 2. Urinary trichloroethanol and trichloroacetic acid concentrations in workers exposed to trichloroethylene were determined by both our direct colorimetric method and Ikeda's oxidation method of chromium trioxide. Correlation between urinary trichloroethanol and trichloroacetic acid determined by Ikeda's method and our direct colorimetric method was observed.泄されるのであろうと言つている.1946年,Forssman,Ahlmark(2)3))はトリクレン蒸気中で働く労働者の訴えと,その尿中三塩化酢酸濃度との関係を見い出し,その75mg/lがトリクレン中毒の警戒すべき限界であると報告した.これに対して,1950年,Frant,Westeadorp(4))は,環境に気中のトリクレン濃度100ppmのもとで働く場合,その尿中には200mg/l濃度の三塩化酢酸を含むと述べられている.現在までは,三塩化酢酸の許容濃度はFrantの成績より75mg/lであるとしている.又,トリクレンの尿中代謝産物には三塩化エタノールのグルクロン酸抱合物もあり,soucek and Vlachova(5))等は1964年に,三塩化エタノールは,三塩化酢酸より排泄量が多く,しかも,排泄速度がはやい事を報告している.著者は実際の作業場で,三塩化エタノール,三塩化酢酸の関係を調べ,気中濃度との関係を求めた.又,三酸化エタノールの定量を池田氏の方法に比べて,簡便な定量を見いだした.そして作業者の尿を用いて,著者等の方法と池田氏の方法との相関を調べた.その成績をここに報告する.

著者

宮田 義昭

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.100, no.9-10, pp.843-855, 1988 (Released:2009-03-30)

参考文献数

31

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The thalamic afferents to the cortical taste area in the cat were studied by retrograde transport of horseradish peroxidase. The taste area extends from the lateral lip of the presylvian sulcus to the posterior part of the orbital gyrus. It is bounded anteriorly and anteromedially by area 6, medially by the fundus and medial bank of the presylvian sulcus, laterally by the first somatosensory area, and posteriorly by the insular area. The taste area receives fibers mainly from the medial smaller-celled part of the posteromedial ventral nucleus (VPMM). Cortical projections of the VPMM form a complicated pattern, but are organized roughly in a topical manner anteroposteriorly. The anterior part of the taste cortex receives fibers from the anterodorsal and posteroventral portions of the anterior two-thirds of the VPMM, whereas the posterior taste cortex receives fibers from the anteroventral, posterodorsal and posterior portions of the posterior two-thirds of the VPMM. In addition, there appears to be a mediolateral organization of cortical projections of the VPMM to the taste area. The taste cortex receives a few projections from the ventral lateral, ventral medial, submedial, paracentral, lateral central, parafascicular and medial central nuclei.

著者

高嶋 成光

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.89, no.3-4, pp.333-360, 1977-04-30 (Released:2009-03-30)

参考文献数

57

被引用文献数

1

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Clinicopathological studies of the histogenesis of the thyroid cancer on the emphasis of morphological features and growth pattern of the occult thyroid carcinoma measuring under 1.0 cm in diameter obtained at autopsy and surgery were performed.The occult thyroid carcinoma observed from the routine section of the thyroid gland obtained from 500 cases at autopsy and 259 cases at surgery were 21 cases (4.2%) and 10 cases (3.9%), respectively. Histological typing were 25 cases of papillary adenocarcinoma and 6 cases of follicular adenocarcinoma.Papillary adenocarcinoma cases were subdivided histologically into sclerosing, cystic and non-sclerosing types. The sclerosing type showed the proliferation of the fibrous connective tissue in the tumor and lymphogenous metastasis with intraglandular metastasis.One case of surgically obtained sclerosing type showed the recurrence and death. The cystic type were enclosed by the capsule and morphologically papillary cystadenocarcinoma. The non-sclerosing type did not show the fibrous connective tissue or capsular formation and smaller compared to the above 2 types. This type suggests the early stage of papillary adenocarcinoma histogenetically.Follicular adenocarcinoma cases were diagnosed according to the atypism of the tumor tissue and in 3 cases capsular formation was observed and in the other cases tumor tissue was directly attached to the thyroid tissue.Metastatic thyroid cancer was found in 12 cases (3.4%) among 349 autopsy cases of the malignant neoplasia. The mode of growth was either diffuse infiltration or solitary nodular formation in the thyroid tissue.Tumor like lesion (51cases, 10.2%) was correspond to the so-called solid cell nest and suggested the squamas metaplasia according to the histological finding of the early histogenesis.

著者

緒方 正名 長谷川 敬彦 高越 良明 竹久 亨 長尾 逸子 寺谷 巌 大隈 義文 人見 硬 長尾 寛 粟屋 研吾 高橋 武夫

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.78, no.1supplement, pp.1-29, 1966-01-30 (Released:2009-08-24)

参考文献数

7

被引用文献数

1

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1) Data has been presented on the trend of Japanese B. Encephalitis from 1959 to 1965 in Okayama, Miyazaki, Kagawa, Tokushima, Kochi, Ehime, Hyogo and Aichi Prefectures, middle and western parts in Japan.2) The prevalence started from Miyazaki, most southern part in Japan, and progressed succesively to Kochi, Okayama, Tottori and Miyagi. The difference in date between Okayama and Miyazaki was 20 days, Okayama and Kochi was 10 days, Okayama and Tottori, adjacent to northern part in Okayama, was 2 days and also the difference in date between northern and southern part in Okayama was 7 days. We woulld like to call this phenomenon “Tendency towards northeast”.This tendency can be arranged in the order of its average atmospheric temperatures. However, there is no correlation between the date of incidence in each year and the temperature gradient.3) From 1950 to 1959, the incidence rate was higher in the southern district than in the northern district, and from 1960 to 1965 it became higher in the northern district than in the southern district of Okayama Prefecture.4) The incidence rate by age from 1960 to 1965 was higher in the old over 60 ages in northern district and in the child below 10 ages in the southern district of Okayama Prefectuve. A marked tendency to decrease the incidence rate in the child has been seen since 1959. This downward tendency would be caused by the J. B. E vaccination.5) There is some indication from the geographycal distribution that the prevalence spreaded from focus to other villages contiguously, except for the town.6) In past five years the district where the incidence rate exceeded over 10/100, 000 peoples three times or exceeded over 20 was shown by the following districts, Northern district in Okayama. PrefectureEastern and western district in Tottori. PrefectureNorthwest district in Hyogo. PrefectureEast and west parts in Kochi. PrefectureSouthern district in Miyagi. PrefectureIn general, the high incidence was observed in the plain near mountain or the basin but not in the town.7) There is a phenomenon that when the incidence rate was over 20 in the year, the incidence rate next year became low.

著者

Hosokawa T.

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.448, pp.593-604, 1927-05-31

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1. Die Cholsäure, welche in Ringerlösung 0.03-0.1% enthalten ist, erhöht das Schlagvolumen des Herzens der Fröche und vermehrt bald die Schlagrequenz, bald setzt sie dieselbe herab. 2. Desoxycholsäure, die in Ringerlösung 0.002-0005% enthalten ist, wirkt auf das Schlagvolumen des Froschherzens vergrössernd, aber auf die Schlagfrequenz herabsetzend. 3. Diese Wirkung ist von der Wasserstoffionenkonzentration der Lösungen ganz unäbhangig. 4. Um die Beeinflussung von N. vagus auszuschliesen, wurde das Herz atropinisiert; auch dieses Herz reagiert auf die Gallensäuren, genau wie ein nicht atropinisiertes Herz. 5. Eine Ringerlösung, welche durch die Leber geflossen ist, erhöht im Vergleich zur Kontrollösung das Schlagvolumen des Froschherzens. Dadurch wurde die Richtigkeit des Versuches von Richardet erwiesen. 6. Die 0.03-0.04% cholsäurehaltige Ringerlösung, die durch die Leber gegangen ist, erhöht im Vergleich mit der Ringerlösung, die auch durch Leber geflossen ist, das Schlagvolumen des Froschherzens mehr. 7. Aus dem Vergleich der das Schlagvolumen verstärkenden Wirkungen der 0.04% cholathaltigen Ringerlösung und dieser Lösung, die durch die Leber gegangen ist, geht hervor, dass die letztere als vordere auf die Herztätigkeit viel stärker wirkt. 8. Margarincholeinsäure, die im Organismus von Natur zu finden müsste, bewirkt dieselbe Erscheinungen, genau wie die Cholsäure und Desoxycholsäure. Aber these Wirkung ist in derselben Konzentration viel schwächer als die der Desoxycholsäure. Dadurch ist es erwiesen, dass der Additionsmechanismus der Desoxycholsäure mit Fettsäuren eine Entgiftungserscheinung ist, und dass diese Erscheinung auch bei der Herztätigkeit auftritt. 9. Kampfercholeinsäure wirkt viel stärker als die Margarincholeinsäure im Sinne der das Schlagvolumen des Herzens verstärkenden Wirkung. 10. Aus diesen Tatsachen folgt, dass das sog. Hormon der Leber von Richardet, welches das Schlagvolumen des Herzens im Sinne sympatischer Erregung fördert, mit den Gallensäuren in innigem Zusammenhang steht. Dadurch scheint mir bewiesen, dass der Gallensäure, die aus der Gallenblase resorbiert in den allgemeinen Kreislauf gelangt, im Sinne der chemischen Regulation der Herztätigkeit eine physiologische Digitaliswirkung zukommt.著者ハ嘗テ抱合膽汁酸ハ犬ノ膽嚢ヨリ吸収セラルル事ヲ實驗的ニ證明シテ其ノ吸収セラレタル膽汁酸ハ何等カ生理的作用アラザルベカラザル事ヲ述ベタリ. 最近高橋及ビRichardet兩氏ハ蛙ノ生肝ヲ長時間灌流シタルリンゲル氏液中ニ蛙心臟ノ交感神經的亢奮ヲ促進セシムル一種ノ「ホルモン」ノ存在スルコトヲ認メテ肝臟ハ心臟ノ生理的作用ヲ調節スル働キヲ有スル「ホルモン」ヲ常ニ分泌スルト稱セリ. 膽汁中ノ抱合膽汁酸ガ腸ヨリ吸収セラレテ肝臟ニ至ル時ハ恰モ膽嚢ヨリ吸収セラレテ大循環系統ニ入ル如ク一部分ハ肝臟ヨリ大循環系統ニ入リテ生理的作用ヲ營ミ得ベキハ考ヘラルルコトナリ, 而モSzilárd氏ノ研究ニヨレバ膽汁酸ガ正常血中ニ存在ストノ報告アルニ於テハ膽汁酸ノ正常血中ニ於ケル生理的作用ノートシテ心臟ニ封スル作用ヲ見テ彼ノ高橋, Richardetノ所謂肝臓「ホルモン」トノ關係ヲ知ルコトハ意義ナキニ非ズ. カカル見地ノ下ニアーシヤー氏變法ヲ用ヒ蛙心ノ驅出量及ビ搏動數ニ對スル膽汁酸ノ作用ヲバ高橋及ビRichardet氏ノ成績ト比較研究シ次ノ結論ヲ得タリ. 抱合膽汁酸ハ唐澤氏ノ實驗ニ明カナル如ク組織内ニ於テハ其ノ成分ニ分カタルルニヨリテ特ニ「ヒヨール」酸及ビ「デゾオキシヒヨール」酸「ナトリウム」ヲ使用シ又「デゾォキシヒヨール」酸ハ動物體内ニ於テハ高級脂肪酸ト「ヒヨレイン」酸ヲ形成スルニヨリ「マルガリンヒヨレイン」酸「ナトリウム」ヲ使用セリ. 1) 0.03-0.1%ニ「ヒヨール」酸鹽ヲ含有セルリンゲル氏液ハ蛙心ノ驅出量ヲ増加ス, 而シテ搏動數ハ或ハ増加シ或ハ減少ス. 2) 0.002-0.005%「デゾオキシヒヨール」酸鹽ヲ含有セルリンゲル氏液ハ蛙心ノ驅出量ヲ増加スレドモ搏動數ヲ減少ス. 3) 此ノ作用ハ溶液ノ水素「イオン」濃度ニ全然無關係ナリ. 4) 「アトロビン」麻痺心ニテモ膽汁酸ハ其作用テ顯ハス. 5) Richardetノ言ヘルト同ジク肝臟ヲ灌流セシメシリンゲル氏液ハ對照液ト比較シテ蛙心ノ驅出量ヲ高ム. 6) 肝臟ヲ灌流セル0.03-0.04%ニ「ヒヨール」酸鹽含有ノリンゲル氏液ハ單ニ肝臟ヲ灌流セルリンゲル氏液ニ比シ蛙心ノ驅出量ヲ増ス. 7) 0.04% 「ヒヨール」酸鹽ヲ含有セルリンゲル氏液ト肝臟ヲ灌流セルコノ液トヲ比較セバ前者ヨリモ後者ハ心臟驅出量ヲ高ムル作用ハ一層強盛ナリ. 8) 多分生體ニ存スベキ「マルガリンヒヨレイン」酸ハ「ヒヨール」酸及ビ「デゾオキシヒヨール」酸ト同様ノ現象ヲ表ハスト雖モコノ作用ハ同一濃度ニテハ遙ニ弱シコレ「デゾオキシヒヨール」酸ト脂肪酸トノ複合物生成機轉ニヨリテ解毒現象ヲ現ハスモノニシテコノ現象ハ心臟ニ對スル作用ニ於テモ顯ハル. 9) 「カンフルヒヨレイン」酸ハ 「マルガリンヒヨレイン」酸ヨリモ一層強キ作用ヲ現ハス. 10) 以上ノ事實ヨリRichardetノ言ヘル心臟驅出量ヲ高ムル作用則チ交感神經的亢奮ヲ促進スル肝臟ノ所謂「ホルモン」ハ膽汁酸卜甚ダ密接ナル關係ヲ有シ肝及ビ膽嚢ヨリ吸収セラレ大循環系統ニ達セル膽汁酸ハ「ヂキタリス」ノ生理的作用ノ如ク心營爲力ヲ化學的ニ調節スルモノノ如シ.

著者

守屋 文夫 何川 凉 橋本 良明

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.103, no.4, pp.455-462, 1991 (Released:2009-03-30)

参考文献数

18

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Poisons and drugs other than alcohol and CO were detected in 17 of all judicial autopsy cases in the Department of Legal Medicine, Okayama University Medical School during the last 12 years. We report 7 cases from the forensic toxicological viewpoint. 1) lethal overdose of Sedes® A, 2) fatal poisoning due to biperiden, thioridazine and nitrazepam taken simultaneously, 3) fatal DDVP poisoning, 4) fatal paraquat poisoning, 5) hypoxic death by inhalation of liquefied petroleum gas, 6) fatal shock induced by sulpyrine, and 7) fatal shock induced by ketoprofen.

著者

Schoda Masato

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.447, pp.443-445, 1927-04-30

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膽汁酸ハ動物ノ種類ニヨリテ異ル. 又膽汁酸ノ種類ハ動物ノ食物ヲ異ニスルニヨリテ差異アルモノノ如ク食物ノ成分ト膽汁酸ノ關係ヲシルニツキテ各種動物ノ膽汁酸ヲ研究スルコトハ意義ナキニ非ズ. 魚類ノ膽汁酸ニツキテハソノ研究吾教室ニ於テ2, 3アルノミ, 余ハ鰆ノ膽汁ニ就キテ研究セルニ膽汁酸ノ主成分ハCholsäuseナルコトヲ確定セリ.

著者

正田 政人

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.447, pp.443-445, 1927

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膽汁酸ハ動物ノ種類ニヨリテ異ル.又膽汁酸ノ種類ハ動物ノ食物ヲ異ニスルニヨリテ差異アルモノノ如ク食物ノ成分ト膽汁酸ノ關係ヲシルニツキテ各種動物ノ膽汁酸ヲ研究スルコトハ意義ナキニ非ズ.魚類ノ膽汁酸ニツキテハソノ研究吾教室ニ於テ2, 3アルノミ,余ハ鰆ノ膽汁ニ就キテ研究セルニ膽汁酸ノ主成分ハCholsäuseナルコトヲ確定セリ.

著者

渡部 昌実

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.1, pp.1-5, 2007

著者

金廣 有彦

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.118, no.1, pp.47-52, 2006-05-01 (Released:2011-06-03)

参考文献数

6

著者

難波 寿夫 大西 弘之 有地 茲 三木 福治郎

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.4, pp.1005-1009, 1960-03-30

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In order to determine the fluctuation of vitamin B(1) in the urine after drinking "Yakult", cow's milk fermented by some sort of "Family Lactbacillaceae", the authors made normal adults and patients with lung tuberculosis drink one bottle (60 cc) a day of Yakult successively, and estimated their content of vitamin B(1) in their urine polarographically and with paper chromatography. Results are as follows. 1. In the case of one bottle (60 cc) of Yakult successively, there occurs a little increment of vitamin B(1) content in their urine of normal adults comparing with tuberculous patients receiving chemotherapy. 2. In the case of taking one bottle of Yakult, no marked effect can be recognized in their urine of tuberculous patients receiving chemotherapy. However, when three bottles (180 cc) of Yakult are given every day, marked increase of vitamin B(1) can be observed even in their urine of the patients, and also impeding factor in polarographical estimation disappears, proving that Yakult is considerably effective in improving vitamin B(1) metabolism.