1 0 0 0 OA 岡山県下で起きた早春室内での凍死例
- 著者
- 石川 隆紀 宮石 智 土井 裕輔 高田 智世 今林 貴代美 稲垣 幸代 吉留 敬 山本 雄二 石津 日出雄
- 出版者
- Okayama Medical Association
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.114, no.3, pp.303-308, 2003-01-31 (Released:2009-03-30)
- 参考文献数
- 11
We encountered two cases of unnatural death occurring indoors in early spring in Okayama Prefecture. The two cases were both females aged 31yearsold and 88yearsold. Autopsies revealed death from hypothermia as the cause of death. The diagnosis of death from cold was not based solely on the characteristic findings of the dead body. After confirming that there were no other accidents and diseases that may cause death, an overall evaluation should be made considering the conditions surrounding occurrence of death from cold. We describe these procedures using these two autopsy cases of death from hypothermia.
1 0 0 0 IR 癌化学療法が奏効しTumor Lysis Syndromeを呈した結腸癌再発症例の一例
- 著者
- 井口 利仁 岩垣 博巳 浜中 荘平 モレイラ ルイスフエルナンド 難波 浩 岡林 孝弘 日伝 晶夫 折田 薫三
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.103, no.11, pp.1171-1176, 1991
A case of recurrence of colon cancer with marked tumor reduction after effective chemotherapy is reported. The patient was a 27-years-old female who was admitted to the 1st department of surgery because of a giant abdominal tumor. She had undergone surgery for cecal cancer 16 months before admission. Abdominal and pelvic CT-SCAN revealed a giant tumor (21×18cm) invading the rectum and uterus. Surgical cannulation was performed into bilateral internal iliac arteries, and anti-cancer drugs (5-FU : 5000mg, ADR : 40mg, CDDP : 200mg) were administered intraarterially. The occurrence of hyperkalemia and striking rises in LDH, CEA, CA19-9 after the chemotherapy strongly suggested the tumor lysis syndrome, which to our knowledge, has not been reported as a complication of the treatment of colon carcinoma.
1 0 0 0 OA 若年型家族性黒内障性白痴の2例
- 著者
- 白髭 郁子
- 出版者
- Okayama Medical Association
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.78, no.2-3, pp.365-386, 1966-03-30 (Released:2009-02-13)
- 参考文献数
- 44
- 被引用文献数
- 1
Two cases of the juvenile form of amaurotic family idiocy were described in the present communication. 1) Case 1 was a 11-year-10-month boy. His family history had consanguinities. He was slightly deteriorated before the onset of the disease. At the age of 5 years, the ataxia of gait was initially manifested. Later there developed the progressive mental deterioration and the “Blitz-Nick- Salaam Krämpfe”. On neurological examinations the marked cerebellar syndroms (ataxia, intention-tremor and hypotonia), the involuntary movements and the narrowing of the ocular vessels could be recognised. Case 2 was 10-year-7-month girl. Her two brothers died of amaurotic family idiocy. She had been healthy until she complained of the myoclonic contractions of the tips of the fingers. The mental deterioration, the convulsive seizures and the visual disturbances were gradually appeared. The neurological examinations showed the involuntary movements, the hypotonia, the optic atrophies and the retinal degeneration. Both patients died six years after the onset of the disease. 2) The autopsy findings of the brains in both cases revealed macroscopically the generalised atrophy and the increased consistency. Microscopically the essential changes were observed in the neuronal swelling and the lipidosis. These changes were distributed ubiquitously throughout the central nerves system and were most markedly in the cerebral cortexes, decreasing by degrees caudally. Furthermore in the case 1, the severest damage was seen in the cerebellar cortex. In the cerebellum of case 1, the entire nerve cell elements except Golgi's cells and the nerve fivers were almost completely obliterated. The swelling of axons in the the cerebral cortexes was recognised in both cases. too. 3) The findings of the organs such as liver, spleen and others in case 2 revealed no lipid accumuration as seen in Niemann-Pick's disease. There were observed the degeneration of the retinal outer layer which was characteristic of the juvenile form of the disease. 4) From the results of the histochemical observations in both cases it was concluded that the intraneuronal substances consisted of the mixture of the sphingomyelin and PAS-positive substances that might be the glycolipid. A part of them and the substances in the fat granulle cells were assumed to be combined with the protein. 5) Above mentioned results, the clinical, the histological and the histochemical findings in both cases indicated the jnvenile form of the disease. In case 1 there would be the developmental anomaly of the brain beside the essential chages of amaurotic family idiocy.
1 0 0 0 OA 葉酸欠乏症の原因に関する研究
- 著者
- 原 功一
- 出版者
- Okayama Medical Association
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.86, no.9-10, pp.453-464, 1974-10-30 (Released:2009-03-30)
- 参考文献数
- 41
Folic acid contents of various foods (147 items) were estimated by the microbioassay using Lactobacillus casei as the test organism. Folic acid were abundant in vegetables, fruits, fishes and the liver of animals. Nineteen foods were examined for loss of folic acid during boiling. Leaching out into the water was also examined. 20-70% of free folate was destroyed after 5 minutes and 20-90% after 15 minutes. Destruction of total folate was less than that of free folate i.e., 30% after 5 minutes and 40-60% after 15 minutes. Pteroylglutamic acid was not destroyed by boiling for 15 minutes. So the folate destroyed during boiling was considered to be other forms of folate except pteroylglutamic acid.Folic acid contents of two hospital diet in Okayayma city was estimated. Mean daily folic acid amount in the diet of hospital A was 205μg of free folate and 839.8μg of total folate. In the diet of hospital B, 305.5μg of free folate and 738.1μg total folate were present. These amounts were much more than those reported in USA and England. As to the reason why megaloblastic anemia is rare and folic acid defi ciency is so mild in Japan, abundant folic acid intake from diets, uniformity of dietary habits i.e. boiled rice as basic food, were discussed.
1 0 0 0 OA XV 放射線治療
1 0 0 0 OA 薬物相互作用(18―降圧薬の薬物相互作用)
- 著者
- 井口 利仁 岩垣 博巳 浜中 荘平 モレイラ ルイス・フエルナンド 難波 浩 岡林 孝弘 日伝 晶夫 折田 薫三
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.103, no.11, pp.1171-1176, 1991
A case of recurrence of colon cancer with marked tumor reduction after effective chemotherapy is reported. The patient was a 27-years-old female who was admitted to the 1st department of surgery because of a giant abdominal tumor. She had undergone surgery for cecal cancer 16 months before admission. Abdominal and pelvic CT-SCAN revealed a giant tumor (21×18cm) invading the rectum and uterus. Surgical cannulation was performed into bilateral internal iliac arteries, and anti-cancer drugs (5-FU : 5000mg, ADR : 40mg, CDDP : 200mg) were administered intraarterially. The occurrence of hyperkalemia and striking rises in LDH, CEA, CA19-9 after the chemotherapy strongly suggested the tumor lysis syndrome, which to our knowledge, has not been reported as a complication of the treatment of colon carcinoma.
1 0 0 0 OA 薬物相互作用(16―抗真菌薬の薬物相互作用)
1 0 0 0 OA 肺移植の現状
- 著者
- 伊達 洋至
- 出版者
- Okayama Medical Association
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.118, no.2, pp.113-117, 2006-09-01 (Released:2011-06-03)
- 参考文献数
- 12
1 0 0 0 OA 薬物相互作用 (11―抗がん剤の薬物相互作用)
1 0 0 0 OA 変形性股関節症
1 0 0 0 OA 老壯年者の心電図に関する研究
- 著者
- 原岡 昭一
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.74, no.1-3, pp.381-392, 1962-03-30 (Released:2009-03-30)
- 参考文献数
- 41
By means of the lead X, Y, Z, the scalar recording of its component, a difference of the electrocardiogram was compared between the young and the old persons. They include the normal healthy and diseased ones. The former consisted of 88 elder and 32 younger persons. In this study, criteria of ventricular hypertrophy were sought.P-wave showed a positive or diphasic one in the lead X, Y, but a negative in the lead Z. QRS-wave also showed a positive one in the lead X, Y, and a diphasic or positive, in the lead Z. T. wave showed a positive one in the lead X, Y, and a negative in the lead Z.The frontal QRS axis calculated from the lead X, Y, exhibited a correlation with the Eintoven's triangle, although the normal range of the former was narrower than that of the latter.It was found that the mean spatial T-magnitude was smaller in the younger aged groups than in the elder groups. in hypertensive patients an increase of the elevational QRS-Vo was considered to be due a shift of the QRS vecthr to the left and posterior. It was also noted that the mean spatial QRS-T angle and QRS, T. magnitude were angmented. The mean spatial T-magnitude showed a decrease upon an elevation of the diastolic presure.Thus, it would seem that R×+R=≤ 20 mm is more quantitative method for criteria of the diagnosis of left ventricular hypertrophy.This leading method is found to be more quantitative method than ever before and to have fewer leading sited of the electrodes. Therefore, it may clinically be useful.
1 0 0 0 OA 指紋上よりみたる日本人の研究
- 著者
- 福元 一男
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.70, no.7, pp.2533-2540, 1958-07-31 (Released:2009-03-30)
- 参考文献数
- 11
1. I took 5.520 (2.740 males and 2.780 females) of the people living in the southern part of Satuma Peninsula as examples of the southern Kyushu inhabitants from among all the Japanese of Kyushu to examine the frequency of the occurrence of the four basic fingerprints. And of the four prints in the cast of males, a type is 1.5%±0.07%; r type 3.2%±0.1%; u type 54.6%±0.30%; and w type 40.7%±0.29%. And in the case of females, a type is 2.1%±0.08%, r type 2.6%±0.09%, u type 59.1%±0.29%, and w type 36.2%±0.28%.2. When the above mentioned frequency of the occurrence of each of the four basic fingerprints is compared with that of the representative one of the Japanese rase, it is found that there is a resemblance to east-share people of Koshikijima (Kagoshima Prefecture), and the Indonesians (Java) as southern race.
1 0 0 0 陽子線治療
1 0 0 0 OA 脳のトランスアミナーゼ
- 著者
- 小野 昌也
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.72, no.2, pp.515-520, 1960-01-30 (Released:2009-03-30)
- 参考文献数
- 16
- 被引用文献数
- 2
ダイコクネズミ脳homogenateを用い,グルタミン酸-アスパラギン酸トランスアミナーゼ(GAT)活性に及ぼす18種の向精神薬,および3種の向神経薬の影響を測定した.1. フエノチアジン系向精神薬は, Prochlorperazineを除く他の6種はいずれもGAT阻害を示し,阻害作用はChlorpromazineに最も強かつた. Chlorpromazine S-oxideはChlorpromazineに比してGAT阻害作用は著しく弱い. 2種のフエノチアジン系向神経薬はGAT活性に影響をみなかつた.2. AzacyclonolはGAT阻害を示し, LSD-25は高濃度で阻害を示したが低濃度では影響を与えなかつた.3, 中枢刺戟剤4種のうち, PipradrolとDMAEは促進, Methylphenidateは影響なく, Tofranilは阻害を示した.4. バルビツール酸系睡眠剤AmobarbitalとPhenobarbital,非バルビツール酸系睡眠剤MethyprylonとGlutethimideは,すべて阻害を示した.しかるにバルビツール酸拮抗剤BemegrideはGATに無影響であつた.抗てんかん剤Primidoneは阻害を示した.5. 実験に用いた中枢抑制剤13種のうち12種が阻害を示した.6. GATに及ぼす作用において, ImipramineとChlorpromazineの類似, DiethazineやPromethazineとChlorpromazineとの差異を,化学構造における2個のN原子間の距離の一致と相異に対応すると考えた.
1 0 0 0 IR 螢光燈による人工照明 臨床編II 石原氏色盲表と螢光燈
- 著者
- 桑原 進
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.67, no.7, pp.1377-1382, 1955-12-31
Reading tests were made with Ishihara's Charts (10th edition) under incandescent lamps, daylight fluorescent lamps. de luxe daylight fluorescent lamps, mixed light of daylight fluorescent lamps and incandescent lamps, and neutral daylight. The result was as follows: The reading accuracy was highest under the de luxe daylight fluorescent lamp, and neutral daylight. the daylight fluorcscent lamp, mixed light of the daylight fluorescent and the incandescent lamps followed in this order with slight differences, and the incandescent lamp was the lowest.
- 著者
- 渡辺 漸
- 出版者
- Okayama Medical Association
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.70, no.12supplement, pp.53-66, 1958 (Released:2009-08-24)
- 参考文献数
- 20
No systemic study to induce leukemia in the experimental animals with the internal irradiation with radioactive isotopes has ever been attempted. We set about experiments with this object in 1953 and succeeded in the induction of experimental leukemia in dt, ddF and ddN uniform strain mice treated with small frequent doses of P32, Sr89 and Ce144.Single dosis of the isotopes ranged from 0.03 to 0.5 μc per gram body weight twice a week was administrated to mice with the methods of intravenous injection, intraperitoneal injection, intratracheal administration and intraesophageal dripping. The total administrations of the isotopes were 7-16 times.The development of leukemia was confirmed in higher frequencies among mice which were administered with small frequent doses of P32. The highest incidence of leukemia throughout our experiments was about 42% in the experiment with P32 at 0.3-0.5 μc level.The development of leukemia remains in lower frequencies among mice which were given small frequent doses of Sr89 or Ce144. In the former cases we confirmed the higher incidence of osteogenic sarcoma. In the latter cases the aplasia of the bone marrow were easily resulted.Among the Beta-emitting radioisotopes the one which has the shorter halflife and more intensive energy such as P32 is more suitable to induce leukemia in mice so far we had experienced.The excessive and at the same time partially abnormal regeneration preceed the development of leukemia after the administrations of small frequent doses of the radioisotopes.The order of the intensity of the radioactivity in the bone after the administration of the radioisotope change from time to time. Such effect will also contribute to enforce the abnormal regeneration of the bone marrow.For the development of leukemia in mice after the administration of the frequent small doses of the radioisotope we should not overlook the most intensive regenerative hematopoietic activity in the bone marrow corresponding middle portion of the long bone such as the femur.
1 0 0 0 OA 發作性血色素尿症ニ關スル知見補遺
- 著者
- 伊藤 駒夫
- 出版者
- 岡山医学会
- 雑誌
- 岡山醫學會雜誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.40, no.3, pp.487-512, 1928-03-31 (Released:2009-03-31)
- 参考文献数
- 54
Das Wesen des Kältehämolysins ist noch nicht völlig aufgeklärt. Der Verfasser hat an 2 Fällen der paroxysmalen Hämolobinurie (die eine gehört nach Dungern und Hirschfeld der O-Blutgruppe, die andere der B-Gruppe an) verschiedene Versuche angestellt, von deren Resultaten die folgenden hier besonders hervor zu heben sind.Nachdem bei Ausführung des Donath-Landsteiner'schen Versuchs als Erythrozytensuspension ausser den eigenen Erythrozyten der Kranken je auch die der A-, B-, AB- und O-Blutgruppe, und als Hämolysin ausser dem nativen Krankenserum auch das in der Kälte vorher mit den roten Blutkörperchen der obigen verschiedenen Gruppen behandelte, sog. Restserum zur Anwendung gebracht worden waren, haben wir gefunden, dass das Autokältehämolysin jedes Kranken am stärksten auf das rote Körperchen der AB-Gruppe, weniger stark auf das der A-Gruppe, viel schwächer auf das der B-Gruppe und ganz schwach oder sogar kaum auf das der O-Gruppe hämolytisch wirkte.Die unnötig lang dauernde Wirkung der Kälte hemmte den Ausfall des D.-L.'schen Versuchs; das rote Blutkörperchen der AB-Gruppe war dabei am stärksten und das der O-Gruppe am schwächsten gegen die Kälte empfindlich.Die 3-malige Vorbehandlung des Serums mit den roten Blutzellen der AB-Gruppe übte keinen Einfluss auf den Ausfall der Wassermann'schen Reaktion des Serums aus.Das Komplement scheint manchmal durch die mehrmaligen Salvarsaninjektionen zum Verschwinden gebracht zu werden, weil danach die sonst positiv ausfallenden D.-L.'schen Versuchsresultate ohne Hinzufügen des Meerschweinchenserums ausblieben. Demzufolge mag es solche Fälle geben, die für klinisch geheilt gehalten werden, wenn auch dort noch das Kältehämolysin nachzuweisen ist.In der Lumbalflüssigkeit der Kranken konnten wir das Auto- wie auch Isolysin nachweisen und durch die subkutane Pituitrininjektion wurden sie sogar vermehrt, und zwar das letztere in erheblicherer Weise, gefunden.
1 0 0 0 IR 諸種製劑ノ河豚毒々性ニ及ボス影響ニ就テ
- 著者
- 加藤 艮六
- 出版者
- 岡山医学会
- 雑誌
- 岡山医学会雑誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.52, no.5, pp.1020-1027, 1940-05-31
Es wurde der Einfluss verschiedener Mittel auf die tum Tode führende Tetrodtoxinvergiftung bei der Maus untersucht, indem man dem Tiere diese Mittel mit der letalen Dosis von Tetrodtoxin gleichzeitig subkutan einführte. Die Versuche erstreckten sich einerseits auf Vitamin C, Omnadin und Erstin, andrerseits auf verschiedene Organpräparate, wie Thyroxin, Lienalin, Opostatin, Yakriton, Interenin, Oporenin, Antasthol, Enarmon und Ovahormon. Die Resultate sind, wie folgt, kurz zusammenzufassen. 1) Vitamin C beeinflusst den Tetrodtoxintod nicht antagonistisch. 2) Omnadin und Erstin; die zum Zwecke der unspezifischen Immuno-Therapiegebraucht werden, scheinen der Vergiftung etwas entgegenzuwirken. 3) Thyroxin, ein Schilddrusenhormon, zeigt einen viel gunstigeren Erfolg, denn sie verlangert nicht nur die Lebensdauer, sondern vermindert auch die Mortalitat der vergifteten Tiere. 4) Yakriton, Interenin, Lienalin, Opostatin, Enarmon und Ovahormon wirken der Vergiftung nicht entgegen. Im Gegenteil verkurzen Oporenin und Antasthol die Lebens dauer.
1 0 0 0 IR 諸種製劑ノ河豚毒々性ニ及ボス影響ニ就テ
- 著者
- 加藤 艮六
- 出版者
- 岡山医学会
- 雑誌
- 岡山醫學會雜誌 (ISSN:00301558)
- 巻号頁・発行日
- vol.52, no.5, pp.1020-1027, 1940
Es wurde der Einfluss verschiedener Mittel auf die tum Tode führende Tetrodtoxinvergiftung bei der Maus untersucht, indem man dem Tiere diese Mittel mit der letalen Dosis von Tetrodtoxin gleichzeitig subkutan einführte. Die Versuche erstreckten sich einerseits auf Vitamin C, Omnadin und Erstin, andrerseits auf verschiedene Organpräparate, wie Thyroxin, Lienalin, Opostatin, Yakriton, Interenin, Oporenin, Antasthol, Enarmon und Ovahormon. Die Resultate sind, wie folgt, kurz zusammenzufassen. 1) Vitamin C beeinflusst den Tetrodtoxintod nicht antagonistisch. 2) Omnadin und Erstin; die zum Zwecke der unspezifischen Immuno-Therapiegebraucht werden, scheinen der Vergiftung etwas entgegenzuwirken. 3) Thyroxin, ein Schilddrusenhormon, zeigt einen viel gunstigeren Erfolg, denn sie verlangert nicht nur die Lebensdauer, sondern vermindert auch die Mortalitat der vergifteten Tiere. 4) Yakriton, Interenin, Lienalin, Opostatin, Enarmon und Ovahormon wirken der Vergiftung nicht entgegen. Im Gegenteil verkurzen Oporenin und Antasthol die Lebens dauer.