著者

Misaki Keizo

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.446, pp.306-310, 1927-03-31

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1. Der Extrakt der Magen-und Dündarmschleimhaut bei experimenteller Hyperglykämie des Kaninchens enthält keine insulinartige Substanz, aber der Extrakt der Blinddarmschleimhaut des normalen Kaninchens zeigt eine vorübergehende Wirkung auf den Blutzucker des normalen Kaninchens. 2. Der Extrakt der Blinddarmschleimhaut bei experimenteller Hyperglykämie bewirkt ziemlich deutlich die Erniedrigung des Blutzuckers des normalen Kaninchens. 3. Nach diesem Befund kann man wohl sagen, dass das Insulin bei experimenteller Hyperglykämie aus der Bauchspeicheldrüse je nach dem Bedarf in die Blinddarmschleimhaut wandert, zur Bildung des Glykogens beitragt und dadurch zur Regulierung des Zuckerverbrauches dient.正常家兎竝ニ萄葡糖注入ニヨリ過血糖ヲ惹起セシメタル家兎ノ胃, 小腸竝ニ盲腸ヨリBanting u. Bestノ變法ニヨリ抽出セル物質ヲ健康ナル正常家兎ニ注射シソノ血糖量ニ及ボス影響ヲ檢シ次ノ結果ヲ得タリ. 1) 過血糖家兎ノ胃及ビ小腸粘膜抽出物ニハ「インシュリン」樣物質ヲ認メザルモ, 正常家兎盲腸抽出物ハ僅微ナル血糖降下作用ヲ有ス. 2) 過血糖家兎ノ盲腸ヨリ抽出セル物質ハ稍著明ナル血糖降下作用ヲ有ス. 3) 過血糖時家兎盲腸粘膜ニ糖原質ノ生成ヲ見タル藤原氏ノ實驗ヨリ此處ニ「インシュリン」樣物質存在シテ糖原質ノ合成ニ關與スルモノト考へ得べシ.

著者

御前 慶造

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.446, pp.306-310, 1927

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正常家兎竝ニ萄葡糖注入ニヨリ過血糖ヲ惹起セシメタル家兎ノ胃,小腸竝ニ盲腸ヨリBanting u. Bestノ變法ニヨリ抽出セル物質ヲ健康ナル正常家兎ニ注射シソノ血糖量ニ及ボス影響ヲ檢シ次ノ結果ヲ得タリ.<br>1) 過血糖家兎ノ胃及ビ小腸粘膜抽出物ニハ「インシュリン」樣物質ヲ認メザルモ,正常家兎盲腸抽出物ハ僅微ナル血糖降下作用ヲ有ス.<br>2) 過血糖家兎ノ盲腸ヨリ抽出セル物質ハ稍著明ナル血糖降下作用ヲ有ス.<br>3) 過血糖時家兎盲腸粘膜ニ糖原質ノ生成ヲ見タル藤原氏ノ實驗ヨリ此處ニ「インシュリン」樣物質存在シテ糖原質ノ合成ニ關與スルモノト考へ得べシ.

著者

北山 加一郎 山本 太郎

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.446, pp.430-436, 1927-03-31

著者

北山 加一郎 山本 太郎

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.39, no.446, pp.430-436, 1927

著者

池尻 孝治

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.77, no.1, pp.59-69, 1965-01-30 (Released:2009-08-24)

参考文献数

51

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As one of the series of studies on radiation leukemogenesis, changes in the peripheral blood picture occurring with lapse of time were pursued with the Cb, D103, StA, and Zb strains of mice (30-50 days old) after a single whole body X-irradiation of 350 r. The results are summarized as follows.1. Both erythrocyte counts and hemoglobin contents showed the minimum values 2 weeks after the irradiation, and after recovering once they tended to decrease again. Reticulocytes decreased to about 2-4‰ immediately after the irradiation but by the second week they increased to about twice the number in normal condition, and thereafter they returned to the normal count. This change was most marked in the D103 strain, but ultimately the changes in the erythrocyte series presented similar curves in all the four strains mentioned above, and these changes did not differ from those observed in RF strain.2. The number of leukocytes decressed rapidly to as low as 2, 000 immediately after the X-irradiation. The susceptibility to X-ray irradiation was higher in the leukocyte series than in the erythrocyte series.3. Lymphopoiesis was more sensitive to X-irradiation than myelogenous hematopoiesis, and the decrease of lymphocytes was greater than that of neutrophils, showing a relative neutrophilia for several weeks after the irradiation.4. After once recovering, the leukocyte counts in the Cb, D103, StA, and Zb strains of mice all did not show such a transient decrease as observed in the preleukemic stage of RF strain about 13 weeks after the irradiation. In addition, lymphocytic leukemia did not develop.5, In the Cb, D103, StA, and Zb strains irradiated with X-ray there could be recognized no severe eosinophilia such as observed in the RF strain that received X-irradiation.From these findings it has been confirmed that there can be recognized no marked differences in the peripheral blood picture immediately after a single whole body X-irradiation of 350 r between the RF strain of mice that develop leukemia by X-ray, and the Cb, D103, StA. and Zb strains that do not develop leukemia by X-irradiation, but in the observations conducted thereafter along with lapse of time there can be seen several distinct differences in the changes of the leukocyte series between them.

著者

岸本 済美

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.71, no.12, pp.8375-8388, 1959-11-30

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Bronchospirometric study was performed with ambient air and oxygen on 46 patients of pulmonary tuberculosis. Entire series were divided into three groups. The first group was consisted of 28 patients where bronchospirometry was made under air and oxygen breathing, alternatively. The test was made on ten patients of the second group where one lung breath air and the other oxygen. The third group was consisted of 8 patients where one lung breath air and the other oxygen following oxygen breathing of both lungs. 1) Decrease of oxygen uptake was marked under air breathing compared to in oxygen breathing in advanced cases of pulmonary tuberculosis. However, no constant changes in oxygen uptake were noted in moderately advanced and minimum cases. 2) Increase of ventiratory volume, respiratory frequency and minute volume were usually noted in the lung which breathes ambient air. Increase of minute volume is marked in the side of better functioning lung. 3) Respriatory equivalent increased in the lung which breathes air, especially marked in advanced and moderately advanced cases. 4) Vital capacity increased slightly in the side breathing air. 5) Bronchospirometry with air breathing can be performed without any undue burden on patients, if the test is limited in ten minutes, and give more precise information of pulmonary function of the affected lung than in ordinary bronchospirometry with oxygen.

著者

岸本 済美

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.71, no.12, pp.8389-8400, 1959-11-30

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1) Effects of surgical treatment of pulmonary tuberculosis, especially, lobectomy, thoracoplasty, extrapleural pneumothorax, segmental and partial resection on respiratory function were studied by bronchospirometry preoperatively andsix months postoperatively. Following results were obtained. 2) Effects on operated lung were most marked in thoracoplasty, and diminished in lobectomy, extrapleural pneumothorax and segmental resection in that order. It was minimum inpartial resection. 3) Decrease of respiratory function was exaggerated in cases where thoracoplasty was supplemented or pleural thickening developed following lobectomy compared to in cases without complications. 4) Decrease of vital capacity was most prominent in all the groups and decrease in oxygen consumption is in the second place. Decrease was minimum in minute volume. 5) In the contralateral lung, compensatory increaseof oxygen uptake and minute volume were noted though vital capacity decreased in all the groups. 6) Effects of extrapleural pneumothorax on respiratory function were variable. Some showed marked increase in ventiratory function, though marked decrease ensued in others.

著者

船隠 恵子 堀田 修次 濱岡 照隆 田阪 武志 立花 広志 村上 敬子 豊川 達也 佐藤 英治 友田 純

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.125, no.1, pp.29-33, 2013-04-01 (Released:2013-05-01)

参考文献数

10

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Ulcerative proctitis (UP) is a prevalent condition associated with increased morbidity, and topical mesalazine (5-aminosalicylic acid [5-ASA]) is known to inhibit the inflammatory processes in UP. We successfully devised mesalazine suppositories, in which 250mg mesalazine was equally distributed and remained stable for at least 2 weeks. We evaluated the effect of using mesalazine suppositories twice a day (BID) on two UP patients. The results demonstrated that mesalazine suppositories were efficacious, well tolerated and safe for the long-term maintenance of UP remission.

著者

萩谷 英大 塩田 澄子 三好 伸一 黒江 泰利 野島 宏悦 大谷 晋吉 杉山 淳一 内藤 宏道 川西 進 萩岡 信吾 森本 直樹

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.125, no.1, pp.35-39, 2013-04-01 (Released:2013-05-01)

参考文献数

22

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A 68-year-old man with alcohol addiction, who lived in the suburbs of Tsuyama, an inland city located in northeast Okayama prefecture, was transported to the emergency unit of the Tsuyama Central Hospital in a state of cardiopulmonary arrest (CPA). Despite rigorous systemic investigation and treatment, the patient died 2 hours after arrival. After his death, Vibrio vulnificus was isolated from his blood culture. Vibrio vulnificus causes fatal infection in humans, usually only in areas located close to the sea where appropriate temperature and suitable salt concentration for its growth are available. Therefore, its occurrence is epidemiologically restricted ; in Japan, the western coastal areas, especially in summers, are reported to be the high-risk regions. This is a rare case because it occurred in a city approximately 50 kilometers from both the Sea of Japan and the Pacific coast of Okayama, and at the end of October in 2011. Economic development and distribution systems have made it possible to transport various food products from coastal areas or abroad to any place in a short time, such that these infections can potentially develop in areas other than expected. We should be aware of the increasing risk of Vibrio vulnificus infection during any season and at any place, especially in patients with abnormal liver function.

著者

内田 勇人 大貫 克英 諸冨 嘉男 青山 英康

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.111, no.1, pp.1-9, 1999-02-28

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This study was designed to clarify the characteristics of height, body weight, body composition and grip strength in Chinese baseball players, and also to examine whether the differences in physical profiles existed by position as the basic data in the country developing a baseball.The subjects were 35 baseball players (19.8±2.3 years) consisting of the champion and the upper distinguished teams in the highest level of baseball tournament in China. The survey was carried out in July and August of 1996 in Tianjin City, China. The mean values of height, body weight and lean body weight (LBW) of Chinese baseball players were 179.7±4.7cm, 77.3±8.6kg and 67.0±6.5kg. Those values were significantly taller and heavier than the average of 20-year-old male persons which lived in Beijing City, China; that is 6.9cm, 18.7kg and 16.1kg, respectively (P<0.01). Chinese pitchers were taller and heavier than Chinese players of other positions. The mean values of height and LBW of Chinese pitchers, infielders and outfielders were significantly smaller (P<0.01) and lighter (P<0.05) than those of professional players in the United States, respectively. Although no significant differences were observed in the mean height and LBW between Chinese pitchers and those of collegiate pitchers in the United States, the mean value of LBW of Chinese pitchers were significantly heavier than those of Japanese collegiate and professional pitchers (P<0.05, respectively). These results are as follows: 1. Baseball players in China are selected based on body muscle mass. 2. Pitchers are selected especially than the players of other positions. 3. As for body muscle mass, there is no difference of body muscle mass between China of developing country and Japan and the states of most developed countries.

著者

蓮池 堯民 吉田 豐太

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.40, no.3, pp.473-486, 1928-03-31

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Die Wirkungsweise des Termins (Tetrahydro-β-Naphthylamine) auf die vegetativen Funktionen, insbesondere auf den Blutdruck, ist noch nicht völlig aufgeklärt worden. Daher haben wir an Kaninchen zuerst die Beeinflussung der Blutdruckkurve durch die einmalige wie auch durch die mehrmalige intravenöse Injektion des Termins untersucht und dann dieselben Versuche nach der Atropin- oder Ergotamininjektion, nach der Durchschneidung des Vagus am Halse und auch nach der Durchschneidung des Halsmarks angestellt. 1) Durch die subkutane Injektion des Termins wurde keine bestimmte Veränderung der Blutdruckkurve hervorgerufen. Durch die intravenöse Injektion einer kleinen Dose desselben wurde nur eine geringe kurzdauernde Erhöhung des Blutdrucks, bei mittlerer oder noch grösserer Dose dagegen eine mehr oder weniger erhebliche Herabsetzung desselben konstatiert und etwa in der Hälfte der Fälle war die anfängliche Herabsetzung von einer leichten Erhöhung begleitet. Bei mehrmaligen Injektionen der mittleren und noch grösseren Dose wurde kein Einfluss auf die anfängliche Druckherabsetzung bemerkt. 2) Die vorangegangene Atropinisierung und die Vagusdurchschneidung am Halse übten keinen Einfluss auf den durch das Termin bedingten Blutdruckkurvenverlauf aus. 3) Die Ergotamininjektion konnte die leichte Erhöhung des Blutdrucks durch die kleine Dose Termin hemmen, aber die Herabsetzung durch die grössere Dose nicht. Nach der Durchschneidung des Halsmarks wurde niemals die Herabsetzung, sondern immer die deutliche und länger als sonst dauernde Erhöhung des Blutdrucks durch das Termin hervorgerufen, welche aber durch die vorangegangene Ergotamininjektion entweder an Grad verringert oder ganz beseitigt wurde oder sogar in das Gegenteil umschlug. Aus all dem wollen wir annehmen, dass die Herabsetzung des Blutdrucks durch das Termin weder von der zentralen noch von der peripheren Vaguserregung, sondern vorwiegend von der Erregung des sympathischen Zentrums, und die Erhöhung des Blutdrucks vorwiegend von der peripheren sympathischen Erregung herbeigeführt wird, und, ferner, dass bei normalen Kaninchen im allgemeinen die zentrale Wirkung der peripheren übergeordnet ist, da ja dort gewöhnlich die Herabsetzung des Blutdrucks durch das Termin im Vordergrunde steht.

著者

吉崎 文彦

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.73, no.1, 1961-03

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The anterior belly of the left digastric muscle of a 75 year old woman was found to be innervated both by the mylohyoid nerve, which entered the deep surface, and by a branch of the stylohyoid branch of the facial nerve, which was distributed in the lateral two-thirds of the more superficial half of the muscle belly. The stylohyoid muscle attached to the hyoid bone by two insertions, neither of which, however, passed superficial to the intermediate tendon of the digastric. It may not be quite impossible to regard this anomaly as showing a transitional stage of the innervation change (Futamura 1906), but origin and course of the anomalous nerve does not agree with that of the embryonal stage. It is suggested, that the part of the normal stylohyoid muscle, which lies superficial to the intermediate tendon, would have been fused to the anterior belly.

著者

村上 昌穂

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.96, no.11, pp.1119-1134, 1984-12-30

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Seven dystonic and eight athetotic patients with cerebral palsy were clinically diagnosed following the classification of motor symptoms of the American Academy for Cerebral Palsy, and examined with surface electromyography while at rest in the supine position, under mental stress, making voluntary contractions and responding to passive stretch. Involuntary movements of both dystonic and tension athetotic cerebral palsy were characterized by nonreciprocal involuntary muscle activity in agonists and antagonists. There was more tonic involuntary muscle activity in dystonic than in tension athetotic cerebral palsy patients. During involuntary movements in three dystonic patients, muscle action potentials recorded simultaneously in different muscles had a uniform pattern of duration and amplitude. Electromyographical findings under mental stress were almost the same as those at rest in both dystonic and tension athetotic forms, except that the amplitude and duration of muscle activity was larger under mental stress than at rest. When both dystonic and tension athetotic patients were asked to make voluntary contractions, they were unable to do so smoothly, because involuntary movements were induced in agonists and antagonists. Especially in dystonic patients, voluntary efforts induced involuntary movements not only in agonists and antagonists but also in other muscles not concerned with voluntary contraction. In all dystonic patients, the responses to passive stretch were characterized by rigidity or rigidospasticity. In five tension athetotic patients, the stretch reflex was characterized by spasticity, but in three patients the stretch reflex was not seen at all. Therefore, it is assumed that dystonic movements arise from rigidity or rigidospastic hypertonus. In three dystonic patients, the stretch reflex brought about action potentials not only in antagonists of the stretched muscle, but also in other muscles not concerned with passive stretch. These synchronized action potentials were neither of involuntary muscle activity induced by passive stretch nor of paradoxical contraction of Westphal. It is presumed that such action potentials are induced by suprasegmental central mechanisms closely related to the stretch reflex.

著者

川北 祝史 宮武 伸行 瀧川 智子 汪 達紘 荻野 景規 沼田 健之

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.2, pp.165-171, 2007-09-03 (Released:2008-07-04)

参考文献数

11

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We compared the status of stress with and without metabolic syndrome in Japanese. We used data for 774 men and 1,136 women who had received annual health checkups at Okayama Southern Institute of Health. Status of stress was evaluated using a stress check provided by the Department of Public Health, Nihon University. Metabolic syndrome is defined by new criteria in Japan. Physical stress was significantly higher in men with metabolic syndrome than in men without it. However, the ability of coping with stress in men with metabolic syndrome was significantly higher than that in men without it. Thus a linkage between metabolic syndrome and the status of stress was characteristic in Japanese men.

著者

細川 敦之 宮本 勉 松野 慎介 川崎 幸子 玉井 豊理 田辺 正忠

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.100, no.9, pp.921-926, 1988

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Ga-67-scintigraphy was performed on 3 patients with malignant lymphoma of the thyroid. Ga-67-accumulation was noted in the primary lesions of two patients. Ga-67-accumulation was seen in an inflammatory lesion, which was not the primary lesion, in the other patient. One of the patients, who was a 48 year-old woman with primary malignant lymphoma of the thyroid, had metastases in the mediastinum, neck and axillar region. The metastases were clearly detected by T1-201 imaging, but Ga-67 did not accumulate in the metastatic foci. It seems that T1-201 is superior to Ga-67 in defining a primary malignant lymphoma of the thyroid.甲状腺原発の悪性リンパ腫は比較的稀な疾患であるが,甲状腺に腫瘤を触知する時には常に鑑別を要する疾患である.私共は3例の甲状腺原発の悪性リンパ腫を経験し,治療前の3例すべてに(67)Ga-citrate似下(67)Gaと略す)シンチグラフィーを施行し,そのうち1例には(201)Tl-chloride(以下(201)Tlと略す)シンチグラフィーを合せ行ない,病巣の進展の描出に(201)Tlが(67)Gaに比べて優れていたので若干の文献的考察を加えて報告する.

著者

小林 由佳 山田 美佐 藤井 裕美 甲 由紀子 魚谷 いづみ 田本 真理子 名田 正子 村井 裕之 角 英 岩垣 博巳 友田 純 斎藤 信也

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.122, no.3, pp.225-229, 2010-12-01 (Released:2011-01-04)

参考文献数

17

被引用文献数

1

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To evaluate the usefulness of the waterless hand washing method for surgical anti-sepsis, we conducted a microbial sampling study, comparing it to a conventional surgical scrub method. A total of 18 operating-room nurses were undertaking the following three-hand washing protocols : scrubbing with blushes using 4w/v% chlorhexidine gluconate (CHG) and also rubbing with CHG, followed by application of a 0.2w/v% CHG with ethanol (HS) preparation. (conventional method); rubbing with CHG and application of HS (two-stage surgical scrub method; TSS); rubbing with anti-septic soap and application of HS (waterless method; WL). Microbial sampling was conducted after hand washing using the glove juice method. No statistically significant differences in bacterial numbers were found among these three methods. The number of bacterially positive subjects was significantly higher in the conventional method than the TSS method. These results indicate that there are adverse effects of blush-scrubbing, as the detected bacteria were related to normal skin flora. As such, the WL method for hand anti-sepsis appears to be equivalent to the conventional surgical scrubbing method in terms of microbial detection. The WL method should therefore be introduced as a standard hand anti-sepsis method at the time of surgery because it is cost-effective as well as time-efficient.

著者

松井 義典

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.94, no.7, pp.p667-672, 1982-08

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The benzethonium chloride method of Iwata for the turbiditometric determination of minute amounts of protein reacted in alkali condition was improved for application to the measurement of urinary protein before and after physical loading. 1) In order to determine minute amounts of protein based on Iwata's method, an improved method was devised. A 0.2ml of urine was added to 3.9ml of a mixture of 33.85mol/l of EDTA 4Na and 0.5mol/l of NaOH. 2) The correlation coefficient of both modified Meulemans method and modified Iwata's one was R=0.96 and the regression equation was y=1.33x+0.17 where x was protein concentration obtained by modified Iwata's method using urine of students before Judo and basketball exercise. The correlation coefficient of both methods was R=0.98 and the regression equation was y=0.91x+0.27 using urine of students agter Judo and basketball exercise. The value obtained by both methods nearl coincided with each other. 3) Turbidity produced by modified Iwata's method was more stable after addition of reagents than that by modified Meulemans method. 4) A minute amount of urinary protein could be preserved and determined by modified Iwata's method up to 4days under freezing at -20℃.