著者

新井 達潤

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.89, no.1-2, pp.21-36, 1977-02-28 (Released:2009-03-30)

参考文献数

59

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Ventricular fibrillation was induced in fifteen monkeys by electric stimulation using a bipolar intracardiac pacemaker electrode which was inserted through a femoral vein. The monkeys were defibrillated and resuscitated after several minutes. Cerebral blood flow (CBF), intracranial pressure (ICP) and EEG were monitored continuously. CBF autoregulation was checked regularly before and after ventricular fibrillation to study the relation between it and other parameters such as CBF, ICP, EEG.Fifteen monkeys were divided into two groups, a burr-hole group and a no burr-hole group. ICP was measured in the burr-hole group (10 monkeys). The purpose of having two groups was to ascertain the effect of a burr-hole (artificial injury in the skull and dura) on the parameters CBF, EEG and autoregulation. CBF was measured with electromagnetic flowmeter at internal carotid artery.The conclusion of the experiment was as follows;(1) Autoregulation was lost in all monkeys after resuscitation. In the monkeys which had had autoregulation before cardiac arrest, the autoregulation recovered in three (no burr-hole group) to five (burr-hole group) hours after resuscitation, if resuscitation took place within five minutes. In the monkeys whose autoregulation had already been lost before cardiac arrest, it did not return despite successful cardiac resuscitation.(2) Immediately after resuscitation, BP, ICP and CBF increased for 20-60 minutes. In the monkeys who had no recovery of autoregulation after resuscitation, the rate of increase of ICP was much larger than those whose autoregulation recovered, and at the peak of ICP, the CBF decreased. Impairment of autoregulation itself, indicates that the ballance of circulatory dynamics of the brain is easily impaired by noxious stimulation such as hypoxia.(3) In the monkeys with recovery of autoregulation, general status was good after resuscitation but in the monkeys without recoverey, symptomes of increased ICP were seen and the prognosis was poor.(4) Six minutes of cardiac arrest would appear to be the upper limit for monkeys to survive after resuscitation.(5) Before ventricular fibrillation, corresponding changes in the CBF and the frequency of the EEG wave recorded, but after resuscitation the frequency of the EEG wave decreased despite an increase in CBF. This is probably the same mechanism as occures in the “luxury perfusion syndrome”.There was no relation between EEG and autoregulation, but when EEG showed dominant slow or flat waves, there was no autoregulation.

著者

杉山 明

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.99, no.3-4, pp.251-260, 1987-04-30 (Released:2009-03-30)

参考文献数

20

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The kinetics of serum ferritin were studied in 42 male patients with alcoholic liver diseases (17 with alcoholic fibrosis, 10 with alcoholic hepatitis and 15 with alcoholic cirrhosis). In addition, the chromatic reaction of biopsied liver tissue to ferritin staining (PAP method) was examined and compared with serum ferritin levels and the iron-staining data. Serum ferritin levels in patients with alcoholic liver diseases, determined immediately after abstinence, were significantly higher than those in normal controls, although no significant difference was noted in serum ferritin among the different disease types. The serum ferritin levels decreased exponentialy after abstinence regardless of the disease type. There were positive correlations between serum ferritin and the intensity of hepatic hemosiderin and between the intensity of hepatic hemosiderin and hepatic ferritin. These correlations indicate that the ferritin level changes according to the amount of hepatic iron stores. These results indicate that hyperferritinemia of patients with alcoholic liver diseases reflects an increase in hepatic iron stores and that the escape of hepatic ferritin due to hepatocellular damage and the reduced clearance of serum ferritin are also related to hyperferritinemia.

著者

高原 光弘

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.91, no.9-10, pp.1235-1248, 1979-10-30 (Released:2009-03-30)

参考文献数

37

被引用文献数

1 1

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Persistent juvenile T wave patterns found in mass examination and in clinical cases were studied for the purpose of clarifying their significance. Persistent juvenile T wave patterns were classified into three types. Type I had negative T waves in lead V1 only, Type II in lead V1 and V2 and Type III in V1 to lead V3 or V4. During mass examinations, persistent juvenile T wave patterns were found in 243 cases (43.5%) of 558 male subjects. Of these, 15 (6.2%) were Type II, III. On the other hand they occurred in 547 (66.5%) of 823 female subjects. Of these, 86 (15.7%) were Type II, III. The incidence of each Type of persistent juvenile T wave pattern did not vary significantly with age, but Type II, III were relatively more frequent between 35 and 49 years of age. Persistnet juvenile T wave patterns were often positive in many cases in electrocardiograms (ECG) thaken from the same subjects 8 years after the first mass examination. Standard ECG's and Frank's system vectorcardiogram (VCG)'s were analysed in 116 clinical cases showing persistent juvenile T wave patterns. Transitional zone and electrical axis deviation in ECGs were almost normal in the persistent juvenile T wave pattern. The shape of the transverse T loop was mostly normal whereas the transverse QRS loop normally varied in shape. Clockwise rotation of the transverse T loop was observed in 15 of 116 clinical cases. The maximum magnitude of the T loop in VCG was significantly smaller in Type III than in Type I, II. Changes in the persistent juvenile T wave pattern on ECG and VCG were studied in 25 cases after administration of Propranolol. The negative T wave in ECG tended to become positive and the maximal T vector tended to become larger shifting towards anterior in VCG after administration of Propranolol. The persistent juvenile T wave pattern was observed more frequently in middle aged women and usually became normal after administration of Propranolol. These results suggest that increased sympathetic tone is one of the pathological mechanisms involoved in the persistent juvenile T wave pattern.

著者

四方 賢一

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.123, no.3, pp.197-206, 2011-12-01 (Released:2012-01-04)

参考文献数

46

著者

水川 展吉 冨永 進 木股 敬裕 小野田 友男 野宮 重信 杉山 成史 川本 知明 山近 英樹 植野 高章 高木 慎

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.3, pp.267-272, 2008-01-04 (Released:2008-07-04)

参考文献数

10

被引用文献数

2 2

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There is a medical team approach used in many hospitals for oral cancer patients. The members are head & neck surgeons and plastic surgeons, or oral surgeons and plastic surgeons. However, in Japan, it is very difficult for oral surgeons to cooperate with head & neck surgeons, except in the case of extractions and oral health care, because both surgeons treat oral carcinomas and there is therefore a conflict in their scope of practice. We believe it desirable for head & neck surgeons to treat oral cancer patients with tumors extending to other regions, and oral surgeons should be in charge of occlusion in head and neck carcinomas. We treated two patients with oral carcinomas in collaboration with head and neck surgeons and plastic surgeons, with head & neck surgeons resecting the tumors, plastic surgeons reconstructing, and oral surgeons (dentists) taking charge of the occlusion for patients in the operating room. This collaboration resulted in patients having good position of the temporomandibular joint and occlusions after the operation. We therefore conclude that this collaborative team approach may be of benefit to the patients.

著者

山元 敦也

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.105, no.5-6, pp.629-639, 1993 (Released:2009-03-30)

参考文献数

13

被引用文献数

1 1

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It was previously reported that the elevation of inorganic fluorine level in plasma after inkalation of methoxyflurane causes acute renal failure. This study investigated whether the peak concentration or the duration of the inorganic fluorine is responsible for the renal failure. Continuous infusion (5 millimols/liter and 10 millimols/liter) or a single intravenous bolus injection (720 millimols/liter) of sodium fluoride solution was administered to rabbits. The plasma concentration and the duration of the plasma fluorine was measured.There werer no signs of pathological or biochemical changes that suggested renal failure when the peak plasma concentration was less than 50 millimols/liter for over 4 hours (5 millimols/liter, 24 hours), or whether peak concentration of plasma inorganic fliorine was over 50 millimols/liter for less than 4 hours (720 millimols/liter, intravenous bolus). However when 10 millimols/liter of sodium fluoride solution was administered at a speed of 10 milliliters/hour for 24 hours, the rabbits showed a peak plasma inorganic fluorine concentration over 50 micromols/liter for more than 4 hours and signs of renal failure developed ata plasma concentration of 65.8 micromols/liter 24 hours after the beginning of infusion. renal failure was mainly inthe form of edema of the tubular cells in both the cortex and medulla and abnormal biochemical changes (blood urea nitrogen 55.8±12.5 milligrams/deciliter, plasma creatinine 1.2±0.1 milligrams/deciliter).Inorganic fluorine can cause renal changes when its paek plasma concentration reaches more than 50 micromols/liter and lasts for more than 4 hours.

著者

松本 尚美 樋口 千草 三橋 利晴 萩谷 英大 高尾 総司 頼藤 貴志

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.134, no.1, pp.35-42, 2022-04-01 (Released:2022-05-02)

参考文献数

16

被引用文献数

1 2

著者

片山 昭

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.91, no.7-8, pp.847-860, 1979-08-30 (Released:2009-03-30)

参考文献数

12

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In order to study the fundamental touch in piano playing, the physiological mechanics of the player and the kinetic mechanics of the swing-stroke system in the piano need to be studied.Equipment for analyzing and measuring the intensity of the swing-strokes has been developed to study the fundamental touch in piano playing. This equipment measures the velocity of the hammer and indicates the relationship of the intensity and the velocity of the swing-strokes.The tone-volume depends on the amount of kinetic energy which the player spends in striking the key. The kinetic energy is in direct proportion to the mass set in motion and is the square of the velocity.The mass set is always constant and the energy depends only upon the velocity of the hammer. Thus it is possible to analyze the tone-volume by measuring the velocity of the hammer.Two methods of swing-strokes were set up to analyze the movement of the swing-stroke. Two experiments were performed: (a) static swing-stroke in which the height of the swingstroke was fixed and the weight was changed and (b) dynamic swing-stroke in which the weight of the swing-stroke was fixed and the height was changed.Experiments with the swing-stroke were made by a skilled pianist. The control system of the intensity of the swing-strokes is discussed.

著者

平木 潔 太田 善介 入野 昭三 三好 勇夫 瀬崎 達雄 原田 英雄 鈴木 信也 大里 尚司 永森 俤一郎 守屋 純一郎 六車 昌士 高杉 潔 駄場崎 浩 池田 一彦

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.77, no.5-6, pp.795-835, 1965-06-30 (Released:2009-03-30)

参考文献数

229

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Morphologic characteristics of most of known oncogenic viruses, some of which were investigated by us, were described in relation to their oncogenicity and their localizations in tumor tissues.Oncogenic viruses were classified into six groups: type A, B, C, D, E and F. Viruses pertaining to type A were presumably not mature virus particles. Some of them could, however, be immature form or incomplete form of oncogenic virus particles. Viruses belonging to type B, C, D, E, and F were represented by mammary tumor virus of mice, leukemia viruses of mice and chickens, polyoma virus, Shope fibroma virus and Lucké renal adenocarcinoma virus, respectively. They were different in size and shape, and in the mode of development.It was presumed that type B and C viruses were members of the Myxovisus group and type D viruses belonged to Adenovirus and the Papova virus group. It was also believed that type E and F viruses had in general the feature of the Pox virus group and Herpes virus group, respectively.

著者

松岡 賢市 青山 一利 小山 幹子 橋本 大吾 朝倉 昇司 一戸 辰夫 谷本 光音 豊嶋 崇徳

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.120, no.1, pp.23-28, 2008-05-01 (Released:2008-07-08)

参考文献数

32

著者

關場 代五郎

出版者

岡山医学会

雑誌

岡山醫學會雜誌 (ISSN:00301558)

巻号頁・発行日

vol.29, no.332, pp.737-743, 1917-09-30 (Released:2009-08-24)

著者

三宅 進 宮村 能子

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.124, no.3, pp.239-241, 2012-12-03 (Released:2013-01-04)

参考文献数

5

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We herein report a case of bilateral frontal horn cysts. The infant was delivered with a low birth weight (1,710g) at 31 weeks, 0 days by emergency Cesarean section. She was severely asphyxiated and exhibited respiratory distress syndrome. Surfactant was administered, and mechanical ventilation was required until 21 days of age. Brain computed tomography (CT) at 45 days of age revealed bilateral cysts adjacent to the frontal horns of the lateral ventricles. Her growth and development were normal. At 1 and a half- years of age, she underwent brain CT again and the above-mentioned cystic abnormality had disappeared. No dilatation or irregularity of the lateral ventricles was found. Normal development and transient abnormal cystic findings in brain CT suggested a diagnosis of frontal horn cysts. Frontal horn cysts should be considered as the causes of cystic lesions of the brain.

著者

高橋 義雄 難波 祐三郎 岸本 晃司 光嶋 勲

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.113, no.3, pp.279-284, 2001-12-31 (Released:2009-03-30)

参考文献数

9

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GENDER IDENTITY DISORDER (GID) is a unique human condition that is classified behaviorally and treated medically with hormones and surgery in the severe form. This condition has been and still somewhat remains controversial by religious beliefs, social institutions and health care delivery systems. We described the surgical management of transsexuals, so called SEX REASSGINMENT SURGERY (SRS) and showed the team for gender treatment, GENDER CLINIC. A gender treatment team composing staff members from the Psychiatric, Plastic Surgery, Urology, Obstetric/Gynecological Surgery, and the Social Service, was established at the Hospital of Okayama University Medical schools in 1999. Female-to-Male procedures include mastectomy, phalloplasty, Phalloplasty are completion and an appurtenance, something pleasing to others. Male-to-Female program includes the genital surgery. The genital change surgery consists of the penile inversion, orchiectomy, vaginoplasty. Other procedures include reduction thyroid chondroplasty, hair transplant, voice change, laryngeal surgery, epilation with the laser.SRS is the only effective treatment available today in the management of GID. The aesthetic and functional results achievable from various procedures are generally satisfactory and are acceptable to the patients. On the other hand, we should remember that the numerous steps of information for SRS will be required.

著者

池口 豪泉

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.119, no.2, pp.153-163, 2007-09-03 (Released:2008-07-04)

参考文献数

35

被引用文献数

1

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The purpose of this study is to analyze the background factors relating to opinions on organ donation through factorial and structural comparisons between Japanese and Americans. The data were obtained from responses to a questionnaire (371 Japanese and 41 Americans).The main findings are as follows:1. Most of the factors, ‘a will for organ donation depending on a recipient’, ‘view of remains’, ‘understanding of brain death’ and so on showed significant differences between Japanese and Americans.2. Japanese had a better understanding of brain death. On the other hand, the ratio of Americans who were willing to donate an organ was higher than that of Japanese.3. It was revealed that “the approval of organ donation for the third person, not only for one's family” had an impact for having donor card showing the approval for organ donation. Furthermore, as underlying factors generating differences on organ transplant opinions, differences were found among Japanese between “approval of organ transplant” and the attitude assuming that oneself or a member of one's family was the person concerned with organ transplantation. There were also differences between Japanese and Americans on ideas about a view for life and death such as soul existence or view of remains.The argument for transplantation in Japan should consider these structural differences.

著者

吉本 弘満

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.1, pp.359-380, 1960

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The author performed quantitative analyses of the amount of urine excreted, the urine density, pH's, microprotine content, urine protein content, the amount of Donaggio reaction-positive substance, urine creatinine, uric acid, urine lactic acid, urine phosphoric acid, and the urine calcium content in the urine before and after work, selected from various groups of persons such as a group of marathon runners, a group of soldiers marching, and a group of ammunition carriers; and obtained the following results.<br>1. In the group of marathon runners whose work is thought to be relatively intense and of a comparatively short duration there can be recognized a rapid decrease in the urine content, an increase in the amount of urine microprotein and in urine protein-positive cases, an increase in the hourly excretion of Donaggio reaction-positive substance, a rapid increase in the density and hourly excretion of lactic acid, a slight decrease in the density and the hourly excretion of creatinine, an increase in the density and hourly excretion of phosphoric acid, and a decrease in the density and hourly excretion of calcium.<br>Judging these estimated values stoistically, it has become possible to obtain significant values in the Donaggio reaction and in the lactive acid with an error of less than one per cent in the hourly excretion contents and similarly significant values in the mucoprotein and phosphoric acid contents under 5 per cent deviation.<br>2. In the marching which is relatively of an intermediate degree of fatigue and of a longer duration, there can be observed a decrease in the quantity of urine, an incrase in the urine density, acidification of the pH, increase in the protein-positive cases, a transient increase and decrease in the excreation of creatinine and the hourly excretion amount, stability of the density and houly excretion of uric acid, a transient increase in the early stage uric acid, and a transient increase in the density and excretion of phosphoric acid. Namely, the substance estimated in this group tend to iucrease at an early stage of the marching but in the terminal stage they tend to return to the normal values.<br>3. In the group of munition carriers whose work is successive from day to day and is of a high degree, there can be recognized a tendency of relatively little change in the urine pH's, an increase in the donaggio value, a transient increase in the density and hourly excretion of creatinine, and also an transient increase in the quantity and hourly excretion of uric acid, revealing a tendency to become orientated to the daily successive labor.

著者

吉本 弘満

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.72, no.1, pp.359-380, 1959-12-30

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The author performed quantitative analyses of the amount of urine excreted, the urine density, pH's, microprotine content, urine protein content, the amount of Donaggio reaction-positive substance, urine creatinine, uric acid, urine lactic acid, urine phosphoric acid, and the urine calcium content in the urine before and after work, selected from various groups of persons such as a group of marathon runners, a group of soldiers marching, and a group of ammunition carriers; and obtained the following results. 1. In the group of marathon runners whose work is thought to be relatively intense and of a comparatively short duration there can be recognized a rapid decrease in the urine content, an increase in the amount of urine microprotein and in urine protein-positive cases, an increase in the hourly excretion of Donaggio reaction-positive substance, a rapid increase in the density and hourly excretion of lactic acid, a slight decrease in the density and the hourly excretion of creatinine, an increase in the density and hourly excretion of phosphoric acid, and a decrease in the density and hourly excretion of calcium. Judging these estimated values stoistically, it has become possible to obtain significant values in the Donaggio reaction and in the lactive acid with an error of less than one per cent in the hourly excretion contents and similarly significant values in the mucoprotein and phosphoric acid contents under 5 per cent deviation. 2. In the marching which is relatively of an intermediate degree of fatigue and of a longer duration, there can be observed a decrease in the quantity of urine, an incrase in the urine density, acidification of the pH, increase in the protein-positive cases; a transient increase and decrease in the excreation of creatinine and the hourly excretion amount, stability of the density and houly excretion of uric acid, a transient increase in the early stage uric acid, and a transient increase in the density and excretion of phosphoric acid. Namely, the substance estimated in this group tend to iucrease at an early stage of the marching but in the terminal stage they tend to return to the normal values. 3. In the group of munition carriers whose work is successive from day to day and is of a high degree, there can be recognized a tendency of relatively little change in the urine pH's, an increase in the donaggio value, a transient increase in the density and hourly excretion of creatinine, and also an transient increase in the quantity and hourly excretion of uric acid, revealing a tendency to become orientated to the daily successive labor.

著者

猪田 宏美 北村 佳久 千堂 年昭

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.127, no.1, pp.59-61, 2015-04-01 (Released:2015-05-01)

参考文献数

7

著者

大塚 愛二

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.133, no.2, pp.104-108, 2021-08-02 (Released:2021-09-01)

参考文献数

8

著者

松原 一志

出版者

Okayama Medical Association

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.99, no.3-4, pp.287-301, 1987-04-30 (Released:2009-03-30)

参考文献数

23

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The infuluence of 2 stout build on the body surface electrocardiogram was studied by comparing the body surface isopotential maps of 93 normal men and 107 obese men without cardiovascular abnormalities. There were no clear differences in the mean map patterns between these groups, although the position of the peak maximum positive potential shifted slightly leftward in the obese group. The maximum positive potentials of the QRS wave (Rmax V) and T wave (Tmax V) at 87 lead points on the left anterior chest and back surface were significantly greater in the obese group. However, on the lower anterior chest surface, the values of Rmax V were smaller in the obese group. The correlations between the Rmax V of the lead points where significant differences between the groups were found and the relative body weight, skinfold thickness, chest configuration, mean frontal QRS axis of ECG, age and respiratory function (% VC, FEV 1.0%) were studied statistically. There were good correlations between Rmax V and the QRS axis and relative body weight. However, there were no apparent correlations between Rmax V and the chest configuration and skinfold thickness. These results suggest that obesity might lead to an increase in abdominal grith and elevation of the diaphragma that produces a mechanical effect on the heart, causing a left-axis shift.

著者

青野 要 山本 道夫 飯田 荘介 内海 耕慥

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.90, no.9, pp.1297-1308, 1978

被引用文献数

1

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In relation to the mechanism by which hemolysis was induced in radiated human erythrocytes <i>in vitro</i>, several inducements of membrane lipid peroxidation and protective effects of V. E and SOD were investigated. Results obtained were as follows:<br>(1) K⁺-release from erythrocytes was accelerated by radiation prior to hemolysis. These accelerated hemolysis and K⁺-release were protected remarkably by V. E and evidently by SOD.<br>(2) Mitochondrial Fe²⁺ induced and Fe³⁺-O₂ generating system - ADP induced lipid peroxidation, and microsomal O₂ generating system - induced lipid peroxidation were also protected by V. E and SOD.<br>(3) Radiation of X-ray or ⁶⁰Co &gamma;-ray accelerated lipid peroxidation of liver homogenate, microsome and liposome. Some of these accelerated lipid peroxidations were protected effectively by V. E and SOD.<br>These results suggest that O₂ and/or OH&middot;generation by radiation induces of membrane lipid peroxidation, which leads deterioration of membrane resulting in the change of ion permeability and then hemolysis.