著者

猪熊 壽 大野 耕一 山本 静雄

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.61, no.10, pp.1153-1155, s・vi, 1999-10

被引用文献数

3 35

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山口大学家畜病院に来院した犬430頭を対象にEhrlichia canisおよびHepatozoon canis抗体保有状況を調査するとともに,感染に関連する要因(年齢,性,品種,屋外室内飼育,住所)を解析した.E.canisおよびH.canis抗体陽性率はそれぞれ4.7と4.2%であった.両抗体とも性および年齢別の陽性率には差が認められなかったが,高い陽性率を示す市町が存在した.また屋外飼育の犬は室内飼育のものに比べて陽性率が高かった.さらにE.canisではビーグル,ゴールデン・レトリバー,ポインター,またH.canisについては秋田,柴,ビーグル,ポインター,雑種といった品種で陽性率が高い傾向がみられた.

著者

TAJIMA Yuko MAEDA Kaori YAMADA Tadasu K.

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

2014

被引用文献数

9

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One hundred and twenty stranding events of Stejneger's beaked whales were reported in Japan between 1999 and 2011. The purpose of this study was to introduce pathological data and to discuss probable causes of death for 44 Stejneger's beaked whales among the reported cases. The significant pathological findings were the pulmonary edema, parasitic granulomatous nephritis, emaciation, amyloidosis, suppurative bronchopneumonia and so on. The probable causes of death were categorized as noninfectious in 43 of the cases, which included drowning, starvation and secondary amyloidosis. One individual was diagnosed with septicemia, which was the only example of an infectious disease. Because we could not always perform advanced analyses, such as microbiology tests, biotoxin examinations or contaminant analyses, the finality of our findings may be impaired. However, the present study has broad implications on the causes of death of Stejneger's beaked whales of the seas around Japan, which are valuable for the future studies and for the detection of emerging diseases.

著者

長谷川 晃久 佐藤 文夫 石田 信繁 福島 康敏 向山 明孝

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.62, no.10, pp.1109-1110, 2000-10-25

被引用文献数

1 52

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馬の性判別を迅速に行なう方法としてY染色体性決定領域(SRY)およびアメロゲニン遺伝子(AMEL)を同時増幅する方法を開発した.これによりY染色体の有無とSRY遺伝子の有無を同時に判定することが可能となり, 本法はXY雌馬症例に対して時間と経験を要する細胞遺伝子学的な分析を行なう前の迅速診断法として有効と考えられた.

著者

Yuya NAKAMOTO Takashi UEMURA Hiroki HASEGAWA Miwa NAKAMOTO Tsuyoshi OZAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0447, (Released:2019-04-30)

被引用文献数

4

---

Many of the reports summarizing neurological disorders in cats considered only a limited disease group(s). There is only one large-scale survey on neurological disorders in cats based on the histopathological viewpoint. We described the localizations and frequencies of neurological diseases in a large population of cats that were referred to the Kyoto Animal Referral Medical Center between 2009 and 2016. We attempted to determine the localization of lesions at the time of the examination in each case and to classify the disease etiologies of these 276 cats with neurological disorders retrospectively. There were 174 cases with lesions in the brain region, 14 cases with lesions in the cervical cord region, 34 cases with lesions in the thoracolumbar cord region, and 54 cases with lesions in the peripheral neuromuscular region. High morbidity rates were observed in cases of idiopathic epilepsy and intracranial tumor in the brain region, spinal cord infarction in the cervical cord region, spinal cord infarction and spinal cord tumor in the thoracolumbar cord region, and peripheral vestibular dysfunction arising from otitis media/interna in the peripheral neuromuscular region. It was suggested that there is a higher number of brain diseases than spinal cord and peripheral neuromuscular diseases in cats. Idiopathic and neoplastic diseases were common in the brain region, vascular diseases were common in the spinal cord region, and infectious diseases were common in the peripheral neuromuscular region.

著者

Yohei MOCHIZUKI Ryohei SUZUKI Yuyo YASUMURA Takahiro SAITO Takahiro TESHIMA Hirotaka MATSUMOTO Hidekazu KOYAMA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0718, (Released:2019-04-02)

被引用文献数

3

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Beta-blockers are used to treat cats with hypertrophic obstructive cardiomyopathy (HOCM). However, there are various hemodynamic responses to beta-blockers. This retrospective study aimed to explore the relationship between the response to carvedilol and the presence of geometric abnormalities. Medical records were reviewed for 16 cats diagnosed with HOCM. Cats were divided into two groups based on the velocity of the left-ventricular outflow-tract after carvedilol treatment (responder: eight cats, non-responder: eight cats). Baseline intergroup comparison revealed that anterior mitral valve leaflet length and diastolic left-ventricular posterior-wall thickness were significantly greater in the non-responder group. Longer anterior mitral valve leaflet and thicker left-ventricular posterior-wall may cause poor response to carvedilol. Thus, these properties may predict a lack of response to carvedilol therapy.

著者

Seoung-Woo LEE Hoon JI Su-Min BAEK A-Rang LEE Min-Ji KIM Sang-Joon PARK Seong-Kyoon CHOI Sungho YUN Tae-Hwan KIM Kyu-Shik JEONG Jin-Kyu PARK

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.2, pp.269-273, 2019 (Released:2019-02-28)

参考文献数

15

---

A 2-year-old castrated male mongrel dog presented with a well-demarcated fluctuant dermal mass, located on the back of the neck. Grossly along with cystic structures filled with a black greasy fluid, when cut open. Microscopically, the mass was multi-lobulated. The lobules consisted of neoplastic basaloid cells and showed central degeneration, forming multiple central cystic structures filled with dark melanin-pigmented materials. Immunohistochemically, the neoplastic cells were strongly positive for CK14 and partially positive for CK19, but negative for CK7, CK8/18, CD34, S-100, Melan-A and α-SMA. Based on the findings, the present case was diagnosed as a feline-type basal cell tumor characterized by cystic structures filled with abundant black fluid.

著者

Hajime ASADA Osamu ICHII Hirotaka TOMIYASU Kazuyuki UCHIDA James K. CHAMBERS Yuko GOTO-KOSHINO Koichi OHNO Yasuhiro KON Hajime TSUJIMOTO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.3, pp.353-356, 2019 (Released:2019-03-14)

参考文献数

8

被引用文献数

1

---

The mutations of TP53 gene are frequently observed in canine histiocytic sarcoma (HS). The objective of this study was to examine the distribution of tumor cells with TP53 gene mutations. Tumor tissues were divided into three or four regions and TP53 gene mutations were examined. TP53 gene mutations were detected only in parts of the HS tissues from six of the eight dogs, and the frequency of the mutant allele varied (0–65%) among the tumor regions. This study suggests that canine HS can exhibit intratumor heterogeneity. Further studies are needed to examine the clinical significance of the intratumor heterogeneity of TP53 gene mutations.

著者

Hidetaka NISHIDA Midori YAMAZAKI Hiroki SAKAI Sadatoshi MAEDA Hiroaki KAMISHINA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.3, pp.365-368, 2019 (Released:2019-03-14)

参考文献数

25

被引用文献数

4

---

A 4-year-old male Toy Poodle was presented with a history of status epilepticus. On presentation, neurological examination revealed a delay in postural reactions in the right pelvic limb. Magnetic resonance imaging showed a fluid-containing cystic lesion that compressed the mesencephalon, hippocampus, and amygdala. The cyst was surgically removed via left rostrotentorial craniotomy. The final diagnosis was an intracranial ectopic choroid plexus cyst. The patient has remained free of seizures for 18 months after surgery. This is the first case report of an intracranial ectopic choroid plexus cyst that was surgically removed in a dog.

著者

Ken OKABAYASHI Takanori NARITA Saki TAKASHIRO Sawako NADAOKA Shuichiro KANAI Daisuke ITO Masato KITAGAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.3, pp.369-372, 2019 (Released:2019-03-14)

参考文献数

16

被引用文献数

5

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This study was undertaken to establish a method for measuring mRNA expression by using real-time RT-PCR in the diagnosis of canine meningiomas. When performing real-time RT-PCR, it is essential to include appropriate control tissues and to select appropriate housekeeping genes as an internal standard. Based on the results of our study, RPS18 constitutes a suitable internal standard for the comparison of mRNA expression between normal meninges and meningiomas. The results showed increased mRNA expression of VEGFA and EGFR; however, mRNA expression of KDR was reduced. Measuring mRNA expression by using real-time RT-PCR with appropriate control tissues and internal standards can provide useful information to understanding the pathogenesis of canine meningiomas, which corresponds with immunohistochemical findings.

著者

Shiori GAMO Teruaki TOZAKI Hironaga KAKOI Kei-ichi HIROTA Kotono NAKAMURA Noriko NISHII Julio ALUMUNIA Masaki TAKASU

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.1, pp.91-94, 2019 (Released:2019-01-08)

参考文献数

15

被引用文献数

4

---

A routine parentage test as part of a conservation program for Kiso horses identified a possible sex chromosome anomaly in a 7 months-old filly because of an aberrant result using LEX3, an X-linked marker. We then analyzed X-linked markers (LEX26, TKY38, and TKY270), Y-linked markers (Eca.YH12, Eca.YM2, Eca.YA16, and the sex-determining region Y gene), and an X/Y marker (Amelogenin gene). This analysis demonstrated that the filly had not inherited an X chromosome from her sire. A karyotyping analysis confirmed that the filly was 63,XO. As it was suspected that the horse would be sterile, we avoided using the horse as a broodmare; the information should also serve to prevent unnecessary conflict between owners transferring and receiving the horse.

著者

Yuto SANO Mai MIYAZAKI Rina YAEGASHI Minoru OKAMOTO Arisa MASUKO Seiya MAEHARA Kazuya MATSUDA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.1, pp.30-34, 2019 (Released:2019-01-08)

参考文献数

26

被引用文献数

1

---

An 8-year-old castrated Toy poodle presented with swelling and proptosis of the right third eyelid caused by an exophytic mass on the bulbar surface. Histologically, the mass was composed of stratified neoplastic basaloid cells, arranged in nests and interconnecting islands, which were mixed with tubular structures. Immunohistochemically, the basaloid cells were positive for p63 and cytokeratin (CK) 14, and the inner epithelial cells of the tubular structures were positive for CK7, CK8, and CK19. According to these findings, the mass was diagnosed as a basal cell adenocarcinoma. Although basal cell adenocarcinoma is rare in animals, it should be included in the list of differential diagnoses for superficial tumors of bulbar conjunctiva of third eyelid in dogs.

著者

Masatoshi KAMATA Shotaro NAGAHAMA Kei KAKISHIMA Nobuo SASAKI Ryohei NISHIMURA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.2, pp.231-234, 2012 (Released:2012-03-02)

参考文献数

13

被引用文献数

8 17

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Behavioral effects induced by intravenous administration of morphine at 0.3, 0.6, 1.2, and 2.4 μg/kg and fentanyl at 5, 10, 20, and 40 μg/kg were evaluated in dogs and cats. In dogs, fentanyl and morphine depressed activity and level of consciousness in a dose- dependant manner. In cats, higher doses of fentanyl stimulated activity temporarily, but excitement, so-called "opioid mania," was not observed. Morphine induced distinctive behavioral changes characterized by sitting with fixed staring, and "opioid mania" was not observed in cats.

著者

Yui KOBATAKE Hiroki SAKAI Hidetaka NISHIDA Yosuke UEMATSU Sadatoshi MAEDA Hiroaki KAMISHINA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.80, no.8, pp.1277-1280, 2018 (Released:2018-08-22)

参考文献数

14

被引用文献数

3

---

An 8-year-old castrated male cat presented with acute ataxia and paresis in all four limbs. The cat also exhibited signs of autonomic nervous system impairment. Magnetic resonance imaging revealed swelling of the brachial plexuses bilaterally. Despite treatment, the cat died after 10 days of treatment. A postmortem examination revealed swollen radial nerves and cervical nerve roots in which infiltration of inflammatory cells was histologically confirmed. Additionally, lymphocytic infiltration was found around the blood vessels of the sciatic nerve bundle and the vagus nerve. Histological features were comparable to previously reported brachial plexus hypertrophic neuritis in a cat. Our case was unique in that the autonomic nerves were also involved in addition to the somatic nerves in all four limbs.

著者

Fumitaka TAKAHASHI Shigenori KOUNO Shinya YAMAGUCHI Yasushi HARA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.17-0553, (Released:2018-12-24)

被引用文献数

1

---

This study investigated cerebral ventricle size and concurrent craniocervical junction abnormality in relation to atlantooccipital overlapping (AOO) in dogs with atlantoaxial instability (AAI). A total of 61 dogs were treated with atlantoaxial ventral fixation. Medical records of each dog, including magnetic resonance (MR) and computed tomography (CT) images, were retrospectively reviewed. CT images were assessed for the presence of AOO and the dogs were then assigned to either an AOO group or a non-AOO group accordingly. CT images were also evaluated to determine the foramen magnum (FM) index. Syringomyelia, cerebellar compression, dorsal compression, and the degree of enlargement of each cerebral ventricle were evaluated using MR images. Of the 61 dogs, 23 had AOO and 38 did not. Furthermore, the ventricle/brain height ratio, the fourth ventricle height/cerebellum length ratio, and the fourth ventricle width/cerebellum length ratio were significantly higher in the AOO group than in the non-AOO group. However, the FM index, third ventricle/brain height ratio, and incidence of syringomyelia did not differ significantly between the two groups. Dogs with concurrent AOO exhibited significantly more dilatation of the lateral and fourth ventricles.

著者

Yusuke WADA Shunsuke NOGUCHI Hiromitsu SASAKI Ai TAKETOMI Mizuho HAMAKAWA Shunsuke SHIMAMURA Terumasa SHIMADA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.80, no.11, pp.1724-1727, 2018 (Released:2018-11-23)

参考文献数

15

被引用文献数

6

---

Canine nasal carcinomas are often treated with radiotherapy. Presence of lysis of the cribriform plate by tumor invasion (stage 4 by modified Adams’s staging system) is a well-known prognostic factor. In this study, dogs with stage 4 disease were divided into two subgroups based on the presence or absence of midline shift of the olfactory or frontal lobes of the brain (Stage 4a: without presence of midline shift. Stage 4b: with midline shift). The median survival time of dogs with midline shift was significantly shorter than that of dogs without midline shift (64 vs. 208 days). Our results indicate that the finding of a midline shift might have a prognostic significance in dogs with nasal carcinoma treated with radiotherapy.

著者

白井 明志 有嶋 和義 政岡 俊夫 高木 博隆 山本 雅子 江口 保暢 赤堀 文昭

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.56, no.2, pp.413-414, 1994-04-15

被引用文献数

1

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ラット胎子動脈管に対するパラコート(PQ)の作用を検索した.PQを25mg/kgの用量で妊娠19〜21日のラットに剖検前3時間に投与した.胎齢19日の午後1時に剖検した胎子では,動脈管の収縮はみられなかったが,胎齢19日の午後4時以降に剖検した胎子では有意な動脈管の収縮がみられた.これらの結果は,PQは胎子動脈管に対して収縮作用をもち,その収縮の臨界期は胎齢19日の前半であることを示すものである.

著者

Mami MURAKAMI Takashi MORI Yasuhiro TAKASHIMA Kisaburo NAGAMUNE Junpei FUKUMOTO Katsuya KITOH Hiroki SAKAI Kohji MARUO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0340, (Released:2018-11-08)

被引用文献数

7

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An 11-year-old cat presented with nasal discharge and lacrimation and was diagnosed with nasal lymphoma. Although the cat showed favorable progression after undergoing chemotherapy, CT imaging demonstrated enlarged pulmonary nodules caused by Toxoplasma gondii. Following the cessation of chemotherapy, the cat was prescribed clindamycin hydrochloride for toxoplasmosis treatment; however, the cat developed kidney lymphoma and died. No T. gondii organisms were observed in the whole body necropsy specimens. It is known that immunocompromised human patients, including those who undergo chemotherapy, are considered at risk for toxoplasmosis. However, the risk of developing toxoplasmosis in cats undergoing chemotherapy is currently unknown. Findings from this case report suggest that cats with chemotherapy-resistant pulmonary masses might have a T. gondii infection rather than metastatic disease.

著者

Yuto SANO Mai MIYAZAKI Rina YAEGASHI Minoru OKAMOTO Arisa MASUKO Seiya MAEHARA Kazuya MATSUDA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0369, (Released:2018-11-06)

被引用文献数

1

---

An 8-year-old castrated Toy poodle presented with swelling and proptosis of the right third eyelid caused by an exophytic mass on the bulbar surface. Histologically, the mass was composed of stratified neoplastic basaloid cells, arranged in nests and interconnecting islands, which were mixed with tubular structures. Immunohistochemically, the basaloid cells were positive for p63 and cytokeratin (CK) 14, and the inner epithelial cells of the tubular structures were positive for CK7, CK8, and CK19. According to these findings, the mass was diagnosed as a basal cell adenocarcinoma. Although basal cell adenocarcinoma is rare in animals, it should be included in the list of differential diagnoses for superficial tumors of bulbar conjunctiva of third eyelid in dogs.

著者

Pan I.C.

出版者

社団法人日本獣医学会

雑誌

日本獣医学雑誌 (ISSN:09167250)

巻号頁・発行日

vol.54, no.1, pp.43-52, 1992-02-15

被引用文献数

1

---

アフリカ豚コレラ(ASF)強毒ウイルスTengani株をVero細胞に馴化してから, そのまま継代培養した場合と, クローニングしてから更に高継代した場合の両方共, 病原性, 免疫原性, 及び感染性の異ったSubpopulationを含むウイルスが容易に産生された. 第27代継代ウイルスの99%以上は接種豚体内で増殖の出来ない非病原性ウイルスであって, 明らかに自然界に存在しない実験室に於ける人工産物であった. 新Subpopulationの病原性の減弱は, 全く均一に起きる訳ではなく, 弱毒化した第27代継代ウイルスを接種した豚個体内では, 血中に連続的に夫々病原性及び免疫原性の異るSubpopulationの出現を見, ある時期に採取した血液材料から強い病原性を有するウイルスが分離出来た. 最初にクローニングを行ってから23代継代培養したウイルスの99.9%は, 接種豚にSubclinicalな感染を起す弱い病原性を示すウイルスであったが, 耐過豚を親株であるTengani株で攻撃した所, 完全な感染防御を示さなかった. Tengani株ウイルス中には, Lisbon '60株と共通の免疫原性を有するSubpopulationと, Tengani株固有のSubpopulationを保有する事が明らかとなった.

著者

Misato NAKAMURA Toshinori YOSHIDA Ayumi EGUCHI Mari INOHANA Rei NAGAHARA Ayako SHIRAKI Nanao ITO Makoto SHIBUTANI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.80, no.2, pp.337-340, 2018 (Released:2018-03-02)

参考文献数

7

被引用文献数

2

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An 18-year-old female black leopard (Panthera pardus) showed renal failure, leukocytosis and presence of subcutaneous masses in the lower abdominal region and right shoulder; she eventually died. Histopathological observations included a mammary gland carcinoma with comedo, solid and tubulopapillary patterns in subcutaneous tissue, and highly proliferated tumor cells in systemic organs. The tumor cells were positive for cytokeratin AE1/AE3. The mammary gland tumor was diagnosed as intermediate-grade adenocarcinoma, based on a previously reported histological grading system of feline mammary carcinomas. Chronic interstitial nephritis was estimated to have been ongoing for 5 years, whilst acute necrotic pancreatitis in relation to tumor metastasis could have been the cause of death.