著者

佐々木 一郎 鈴木 正 石井 文由

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.41, no.10, pp.1055-1060, 1992-10-20 (Released:2009-10-16)

参考文献数

29

被引用文献数

3 3

---

The degree of lytic action due to interactions between nonionic surfactants and liposomes was determined in terms of affinity for lipid membranes. The solubilization potential of some surfactants toward liposome membranes was estimated based on physicochemical measurements such as fluorometry to detect the release of fluorescent markers (calcein) from liposomes, turbidimetry in suspensions and surface tensiometry. The lytic action of the alkyl poly (oxyethylene) ether (POE) toward lipid membranes was greatest when the alkyl and ethylene oxide chain lengths were 12 and 8, respectively. The lytic action of nonionic surfactants with various hydrophobic portions (hydrogenated caster oil POE ethers, cholesteryl POE ethers, nonylphenyl POE ethers and POE stearate) was found to depend on structure. Maximum activity in each homologous series was 1.2 I.O.B. (Inorganic Organic Balance).The critical micelle concentrations (cmc) of dodecyl POE (5) and POE (10) ether in the absence and presence of liposomes were determined using a surface tension meter. Addition of liposomes caused cmc of the surfactants to increase. Dodecyl POE (5) ether causes marker release at lower concentration than cmc without change in turbidity. Dodecyl POE (5) ether concentration increase further, marker release from liposomes greatly increase minor change in turbidity. For dodecyl POE (10) ether, marker release started from cmc with decrease in turbidity. The lytic action of nonionic surfactants on liposomes would thus appear related to their capacity formixed micelle formation with phospholipids.

著者

田村 隆光

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.42, no.10, pp.737-745, 1993-10-20 (Released:2009-10-16)

参考文献数

49

被引用文献数

1 1

---

The existing test methods for measuring foaming and antifoaming properties of liquids are reviewed. The foaminess of liquids strongly depends on the test method. A number of methods cover most aspects of foam formation and stabilization. According to the principal of the foam generation, the foaming methods have been classified into two groups ; static and dynamic. The foam stability are expressed in terms of defined parameter such as the lifetime of bubbles, bubble size distribution and the gradual transformation of foam film caused by drainage.

著者

奥村 烝司

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.35, no.4, pp.254-259, 1986-04-20 (Released:2009-11-10)

参考文献数

13

著者

Sahar Y. Al-Okbi Doha A. Mohamed Thanaa E. Hamed Amr E. Edris Karem Fouda

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.67, no.3, pp.345-353, 2018 (Released:2018-03-01)

参考文献数

58

被引用文献数

7 8

---

The aim of the present research was to investigate the effect of fish oil, crude Nigella sative oil and combined fish oil/Nigella sative volatile oil as hepato-regenerative and renal protective supplements. The oils were administered as emulsions to rat model with liver injury induced by CCl4. Plasma activities of transaminases (AST and ALT) were evaluated as liver function indicators, while plasma creatinine and urea and creatinine clearance were determined as markers of kidney function. Plasma malondialdehyde (MDA), nitrite (NO) and tumor necrosis factor-α (TNF-α) were estimated to assess the exposure to oxidative stress and subsequent inflammation. Liver fat was extracted and their fatty acids´ methyl esters were determined using gas chromatography. Results showed that plasma activities of AST and ALT were significantly higher in CCl4 control group compared to control healthy group. Plasma levels of creatinine and urea increased significantly in CCl4 control, while creatinine clearance was reduced significantly in the same group. All rat treated groups given the three oil emulsions showed improvement in liver function pointing to the initiation of liver regeneration. The combination of fish oil/Nigella sative volatiles showed the most promising regenerative activity. Oxidative stress and inflammation which were increased significantly in CCl4 control group showed improvement on administration of the three different oil emulsions. Fatty acids methyl ester of liver fat revealed that rats treated with fish oil/Nigella sative volatile oil presented the highest content of unsaturated fatty acids (45.52% ± 0.81) while fish oil showed the highest saturated fatty acids (53.28% ± 1.68). Conclusion; Oral administration of oil emulsions of native fish oil, Nigella sative crude oil and combined fish oil/Nigella sative volatile oil reduced liver and kidney injury in rat model of CCl4 through exerting anti-inflammatory and antioxidant activity. Fish oil/Nigella sative volatile oil emulsion was the most promising hepato-regenerative and reno-protective formula among the different groups.

著者

阿部島 杞干

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.28, no.10, pp.700-708, 1979-10-20 (Released:2009-11-10)

参考文献数

34

被引用文献数

3 2

著者

鈴木 平光

出版者

Japan Oil Chemists' Society

雑誌

日本油化学会誌 (ISSN:13418327)

巻号頁・発行日

vol.48, no.10, pp.1017-1024,1197, 1999-10-20 (Released:2009-11-10)

参考文献数

72

被引用文献数

3 3

---

魚油には, ドコサヘキサエン酸 (DHA) やエイコサペンタエン酸 (EPA) といったn-3系多価不飽和脂肪酸が豊富に含まれている。これらの脂肪酸は, 心血管系疾患, がん, 炎症の予防に有効であるため, 生物学的に重要な脂質として広く認められている。さらに, 魚油, 特にDHA, の摂取は, 脳の発達, 記憶学習能, 視覚機能に影響するということが多くの研究で明らかにされている。最近では, 痴呆症や精神障害に及ぼすDHA油の予防及び治療効果が報告されている。この総説では, 魚油の健康機能についてまとめると同時に, 高齢者の知能や視力に及ぼすDHA油の効果についてのデータも紹介する。

著者

榊原 敏之

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.39, no.7, pp.451-458, 1990-07-20 (Released:2009-10-16)

参考文献数

34

被引用文献数

1

---

Of the hydrophilic groups functioning as surface-active agents, sugar esters of the higher fatty acid have long been known. Recently, alkyl glycosides have been found to be similar surface-active agents, and are being applied domestically as detergents for kitchen and so forth.Several properties have been observed which have lead to the use of alkyl glycosides. They are nonionic surface-active agent, with high stability and good lathering. They are also low in toxicity, low in skin irritability, and is biodegradable. Alkyl glycosides are not just surface-active agents, however. They can be used in cellulose processing, are enzyme stabilizers, have applications in the biochemical field, and are components used in artificial cell (liposome). In the future, it is to be supposed, functional compounds containing sugar components, such as alkyl glycosides, will see increasingly wide-spread use.

著者

土屋 文安

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.19, no.8, pp.757-764, 1970-08-20 (Released:2009-10-20)

参考文献数

72

被引用文献数

1 1

著者

三輪 トーマス完二

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.27, no.10, pp.650-657, 1978-10-20 (Released:2009-11-10)

参考文献数

39

被引用文献数

1 1

著者

島村 馬次郎

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.34, no.8, pp.599-605, 1985-08-20 (Released:2009-11-10)

参考文献数

64

著者

Yoshimune Nonomura Momoka Sano Ryota Sekine Yoshiyuki Daikoku

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

pp.ess21210, (Released:2021-11-09)

被引用文献数

2

---

Surface treatment of wood surface is an effective method to improve the physical properties. The friction dynamics of wood coated with vegetable oil were evaluated and compared to wood treated with polyurethane and untreated wood. The kinetic friction coefficient, µk, was 0.39±0.01, which was smaller than the values for polyurethane–treated wood and untreated oak. The effect of the surface treatment was also observed in the dependence of velocity on the friction coefficient. The friction profile of the wood surface treated with vegetable oil was similar to that of untreated wood, and the friction coefficient was nearly constant, except in the static friction region of sliding out. These results suggest that wood treated with vegetable oil is suitable for inducing a smooth feel.

著者

Kürşat Karaman Sibel Kizil Merve Başak Bülent Uzun Engin Yol

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.70, no.11, pp.1631-1640, 2021 (Released:2021-11-03)

参考文献数

75

被引用文献数

7

---

Reducing allergenicity and increasing oleic content are important goals in groundnut breeding studies. Ara h 1 is a major allergen gene and Delta(12)-fatty-acid desaturase (FAD2) is responsible for converting oleic into linoleic acid. These genes have homoeologues with one copy in each subgenome, identified as Ara h 1.01, Ara h 1.02, ahFAD2A and ahFAD2B in tetraploid groundnut. To alter functional properties of these genes we have generated an Ethyl Methane Sulfonate (EMS) induced mutant population to be used in Targeting Induced Local Lesions in Genomes (TILLING) approach. Seeds were exposed to two EMS concentrations and the germination rates were calculated as 90.1% (1353 plants) for 0.4% and 60.4% (906 plants) for 1.2% EMS concentrations in the M1 generation. Among the 1541 M2 mutants, 768 were analyzed by TILLING using four homoeologous genes. Two heterozygous mutations were identified in the ahFAD2B and ahFAD2A gene regions from 1.2% and 0.4% EMS-treated populations, respectively. The mutation in ahFAD2B resulted in an amino acid change, which was serine to threonine predicted to be tolerated according to SIFT analysis. The other mutation causing amino acid change, glycine to aspartic acid was predicted to affect protein function in ahFAD2A. No mutations were detected in Ara h 1.01 and Ara h 1.02 for both EMS-treatments after sequencing. We estimated the overall mutation rate to be 1 mutation every 2139 kb. The mutation frequencies were also 1/317 kb for ahFAD2A in 0.4% EMS and 1/466 kb for ahFAD2B in 1.2% EMS treatments. The results demonstrated that TILLING is a powerful tool to interfere with gene function in crops and the mutagenized population developed in this study can be used as an efficient reverse genetics tool for groundnut improvement and functional genomics.

著者

永山 升三 伊佐 弘

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.28, no.12, pp.881-889, 1979-12-20 (Released:2009-11-10)

参考文献数

107

被引用文献数

1 1

著者

原 一郎

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.20, no.10, pp.658-662, 1971-10-20 (Released:2009-11-10)

参考文献数

20

著者

柏 一郎 田村 良一 橋本 茂

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.28, no.8, pp.560-564, 1979-08-20 (Released:2009-11-10)

参考文献数

8

被引用文献数

1

---

Some proteins which construct human hair were solubilized in aqueous solutioons of surfactants generally applied for shampoos. 1) The aqueous solution of sodium dodecylpoly (oxyethylene) sulfate solubilized smaller amounts of proteins from the hair than that of other surfactants used in this experiment. 2) The amount of solubilized proteins had the relationship with the degree of damage in hair. The higher damaged hair gave larger amounts of solubilized proteins. 3) Solubilization of proteins was influenced with pH of the solution. The minimum amount of solubilized proteins was obtained at pH 56 corresponding to the isoelectric point of human hair. 4) The hair of which proteins was extracted with an aqueous solution of the surfactant had poor water holding capacity and gave much splitted hair caused by combing. These facts have provided valuable imformation on the effect of surfactants on human hair.

著者

松下 雪郎

出版者

Japan Oil Chemists' Society

雑誌

油化学 (ISSN:18842003)

巻号頁・発行日

vol.20, no.4, pp.195-204, 1971-04-20 (Released:2009-11-10)

参考文献数

73

被引用文献数

2 3

著者

Alexander I. KUZMENKO Etsuo NIKI Noriko NOGUCHI

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.50, no.6, pp.497-506, 2001 (Released:2009-07-28)

参考文献数

21

被引用文献数

7 13

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The antioxidizig action of 20-hydroxyecdysone was investigated in several systems in vitro. Changes in the parameters of chemiluminescence in the presence of 20-hydroxyecdysone were found in rat liver mitochondrial fractions. The effect of 20-hydroxyecdysone on methyl linoleate micelles free radical oxidation was studied. The rate of oxygen uptake in methyl linoleate micelles was found to be smaller when 20-hydroxyecdysone was present than at its absence. The action of 20-hydroxyecdysone in the liposomal membranes oxidation was investigated be means of α-tocopherol consumption. A lower rate of α-tocopherol consumption in the oxidation of liposomal membranes was found when 20-hydroxyecdysone was present.   The effect of cholesterol on free radical formation in liposomal membranes was investigated. The rate of free-radical formation was smaller when cholesterol was present in the membrane than in membranes free of cholesterol. The α-tocopherol antioxidant effect in the membrane was also lower when cholesterol was present. We show here for the first time that 20-hydroxyecdysone has an antioxidant action in combination with α-tocopherol in membranes with cholesterol overload. Kinetic measurements were revealed the 20-hydroxyecdysone antioxidant effect on free radical reactions in membranes.

著者

Naohiro Gotoh Satoshi Kagiono Kazuaki Yoshinaga Hoyo Mizobe Toshiharu Nagai Akihiko Yoshida Fumiaki Beppu Koji Nagao

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.67, no.3, pp.273-281, 2018 (Released:2018-03-01)

参考文献数

29

被引用文献数

5 19

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The intake of trans fatty acids (TFAs) in foods changes the ratio of low density lipoprotein (LDL) to high density lipoprotein (HDL) cholesterol in blood, which causes cardiovascular disease. TFAs are formed by trans isomerization of unsaturated fatty acids (UFAs). The most recognized formation mechanisms of TFAs are hydrogenation of liquid oil to form partially hydrogenated oil (PHO,) and biohydrogenation of UFAs to form TFA in ruminants. Heating oil also forms TFAs; however, the mechanism of formation, and the TFA isomers formed have not been well investigated. In this study, the trans isomerization mechanism of unsaturated fatty acid formation by heating was examined using the model compounds oleic acid, trioleate, linoleic acid, and trilinoleate for liquid plant oil. The formation of TFAs was found to be suppressed by the addition of an antioxidant and argon gas. Furthermore, the quantity of formed TFAs correlated with the quantity of formed polymer in trioleate heated with air and oxygen. These results suggest that radical reactions form TFAs from UFAs by heating. Furthermore, trans isomerization by heating oleic acid and linoleic acid did not change the original double bond positions. Therefore, the distribution of TFA isomers formed was very simple. In contrast, the mixtures of TFA isomers formed from PHO and ruminant UFAs are complicated because migration of double bonds occurs during hydrogenation and biohydrogenation. These findings suggest that trans isomerization by heating is executed by a completely different mechanism than in hydrogenation and biohydrogenation.

著者

Naoki Takatani Fumiaki Beppu Yumiko Yamano Takashi Maoka Masashi Hosokawa

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.70, no.4, pp.549-558, 2021 (Released:2021-04-02)

参考文献数

29

被引用文献数

1

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β-Apocarotenoids are the cleavage products of β-carotene. They are found in plants, carotenoid-containing foods, and animal tissues. However, limited information is available regarding the health benefits of β-apocarotenoids. Here, we prepared seco-type β-apocarotenoids through the chemical oxidation of β-carotene and investigated their anti-inflammatory effects against activated macrophages. Oxidation of β-carotene with potassium permanganate produced seco-β-apo-8’-carotenal, in which one end-group formed an “open” β-ring and the other was cleaved at the C-7’,8’ position. In lipopolysaccharide-stimulated murine macrophage-like RAW264.7 cells, seco-β-apo-8’-carotenal inhibited the secretion and mRNA expression of inflammatory mediators such as nitric oxide, interleukin (IL)-6 and IL-1β, and monocyte chemoattractant protein-1. Furthermore, seco-β-apo-8’-carotenal suppressed phosphorylation of c-Jun N-terminal kinase and the inhibitor of nuclear factor (NF)-κB as well as the nuclear accumulation of NF-κB p65. Notably, since seco-β-apo-8’-carotenal exhibited remarkable anti-inflammatory activity compared with β-apo-8’-carotenal, its anti-inflammatory action could depend on the opened β-ring structure. These results suggest that seco-β-apo-8’-carotenal has high potential for the prevention of inflammation-related diseases.

著者

Jin Liu Weiming Wang Limin Chen Yachai Li Shuimiao Zhao Yijuan Liang

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.70, no.5, pp.675-683, 2021 (Released:2021-05-01)

参考文献数

35

被引用文献数

7

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Cyclophosphamide (CP) is very well-known anticancer drug and commonly used against various cancers. CP therapy is related to female ovarian cancer and causes female infertility. The ovarian cancer associated with the increase oxidative stress and inflammatory reaction. Syringic acid (SA) is very well phyto-constituent and already proof antioxidant and anti-inflammatory effects on various diseases. We investigated the chemoprotective impact of SA on CP mediated ovarian damage, and the underlying mechanism. CP (75 mg/kg) was used to cause ovarian damage and rats were randomly divided into separate groups and received a different dose of SA for 14-day. Body weight, food and water intake were determined. Ovarian weight and tumor index was measured. Antioxidant parameters were determined in the serum and ovarian tissue. Pro-inflammatory cytokines, apoptosis parameters and inflammatory mediators were estimated in the serum. Hormonal parameters and Histomorphometry were estimated. Dose dependently treatment of SA significantly (p < 0.001) decreased the levels of biochemical parameter such as nitric oxide (NO), myeloperoxidase (MPO) and augmented the antioxidant parameters include catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD) and reduced malondialdehyde (MDA) level in serum and ovarian tissue. SA treatment significantly (p < 0.001) suppressed the level of luteinizing hormones (LH), anti-mullerian hormone (AMH), estradiol (E2) and folliclestimulating hormone (FSH) as well as ovarian follicles. SA significantly (p < 0.001) down-regulated cytokines, inflammatory mediator and caspase-3 parameters. Taken altogether, we conclude that SA considerably reduced ovarian damage via reduced oxidative stress and inflammatory reaction.