著者

大西 肇

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.41, no.5, pp.466-467, 1983-05-01 (Released:2009-11-13)

著者

早川 謙二 兼松 顕

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.44, no.2, pp.109-117, 1986-02-01 (Released:2009-11-13)

参考文献数

58

被引用文献数

6 7

---

This article reviews the recent advances in the intramolecular Diels-Alder reactions of furans, which include the reactions with furan as a diene (type I), furan as a part of diene (type II), and furan as a dienophile (type III). This review involves the analysis of the important controlling factors in these reactions as well as their application to the natural product synthesis.

著者

大橋 裕二

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.58, no.4, pp.334-338, 2000-04-01 (Released:2009-11-13)

被引用文献数

1

著者

岩井 清明

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.41, no.11, pp.1110, 1983-11-01 (Released:2009-11-13)

著者

野依 良治

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.50, no.12, pp.1131-1139, 1992-12-01 (Released:2009-11-16)

参考文献数

26

被引用文献数

8 8

---

Homogeneous catalysis using chiral metal complexes provides a general principle for chemical multiplication of chirality. A wide range of optically active substances can be synthesized catalytically by the appropriate combination of transition metals or main group elements and suitably designed chiral organic elements. This chemistry is useful not only for stereoselective preparation of chiral compounds in laboratories but also even on industrial level. The recent progress in this field greatly raised the potential of organic synthesis in general. The current status is discussed.

著者

渡嘉敷 通秀

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.43, no.7, pp.703-716, 1985-07-01 (Released:2009-11-13)

参考文献数

69

被引用文献数

2 2

---

Mineral oils are made by refining crude oils with physical operations. On the other hand, synthetic oils are products made by combining low molecular weight components from mineral oil or natural oils and fats via various chemical processes.Those are classified into several categories such as synthetic hydrocarbons (α-olefin oligomer, alkylbenzene, etc.), esters (diester, polyol lester, phosphate, silicate, etc.), ethers (polyalkyleneglycol, polyphenylether) and others (silicone, fluorinated compounds, etc.). Some synthetic fluids show better properties in which mineral oils are poor ; for examples, in viscosity-temperature relations, low tempreature fluidities, high temperature stabilities, fire resistances, etc.Recently, these synthetic oils are getting more important in connection with energy conservation or development of high performance machines. They are applied mainly to aircraft gas turbine oils, automotive engine oils, hydraulic oils, compressor oils and gear oils.In this review, synthetic lubricating oils are introduced for research chemists and chemical engineers of organic syntheses.

著者

小林 淳一 津田 正史

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.55, no.12, pp.1114-1123, 1997-12-01 (Released:2009-11-16)

参考文献数

37

被引用文献数

4 7

---

Manzamines, β-carboline alkaloids having unique heterocyclic systems from marine sponges, are of considerable current interest as compounds generated through unprecedented biosynthetic path or as a challenging target for total synthesis. Recently many manzamine-related alkaloids have been isolated from marine sponges, indicating the unique biogenetic path of manzamines.

著者

北川 敏一 竹内 賢一 小松 紘一 木下 知己

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.50, no.8, pp.746-757, 1992-08-01 (Released:2009-11-16)

参考文献数

44

被引用文献数

2 3

---

Two novel classes of hydrocarbons, i.e. hydrocarbon salts and ionically dissociative covalent hydrocarbons, were prepared from Kuhn's carbanion (5-) and various cyclopropenylium and tropylium ions.The ionic structures of the hydrocarbon salts were evidenced by IR spectra (solid state), UV-vis spectra (DMSO), and electric conductivity measurements (DMSO) The salt obtained from 5- and tricyclopropylcyclopropenylium ion formed a unique covalent compound in chloroform which can exist only in solution. The salt of 5- and tricyclopropyltropylium ion was found to undergo both coordination and single-electron transfer in THF, affording a yet unknown type of equilibrium system, in which the ionic, radical, and covalent species coexist.Studies on the free energies of heterolysis of the newly synthesized covalent hydrocarbons revealed the importance of the steric effect in the heterolytic cleavage of σ carbon-carbon a bond. It was also found that a slight difference in the cation stability differentiates the product, either ionic or covalent, of the reaction with a carbanion.

著者

濱口 浩三

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.46, no.11, pp.1052-1060, 1988-11-01 (Released:2009-11-13)

参考文献数

37

被引用文献数

1 1

---

In this review I first described the stability of proteins obtained from unfolding experiments and how the replacement of a specified amino acid residue with other residues in a protein affects the protein stability. Second, I described the kinetics of unfolding and refolding of proteins. The transition from folded state to unfolded state or from unfolded state to folded state is highly cooperative, and no structural intermediate is detected. Therefore, it is difficult to understand how the regular structure of the native protein is formed from the unfolded molecule. Finally I described the pathway of the disulfide bond formation from reduced proteins.

著者

冨永 博夫

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.26, no.8, pp.699-705, 1968-08-01 (Released:2009-11-13)

参考文献数

32

著者

冨士 薫 野出 学

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.42, no.3, pp.193-205, 1984-03-01 (Released:2010-01-22)

参考文献数

76

被引用文献数

9 9

---

A carbon-heteroatom bond has the hard-soft dissymmetry as well as the charge dissymmetry. Thus, a pertinent combination of a hard acid and a soft nucleophile can cleave the carbon-heteroatom bond. This article describes a number of combination systems of a hard Lewis acid and a soft nucleophile which have been developed for the cleavage of C-O, C=C, C-NO2, and C-X bonds.

著者

刈米 孝夫

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.43, no.8, pp.798-806, 1985-08-01 (Released:2009-11-13)

参考文献数

27

---

I discussed progressive processing of soap, alkylbenzene, long chain alcohols, α-olefin and synthetic surface active agents connected with foreign situation.Also it is described the changing of inorganic builders, other additives, their formulation and various kinds of continuous sulfation/sulfonation processes by SO3-gas and finally estimated the future trend of synthetic detergent and their related field.

著者

中村 倭文夫

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.26, no.1, pp.23-36, 1968-01-01 (Released:2009-11-13)

参考文献数

114

被引用文献数

1 3

著者

明石 満 赤木 隆美

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.62, no.5, pp.520-528, 2004-05-01 (Released:2009-11-13)

参考文献数

44

被引用文献数

1 1

---

Monodisperse polymeric nanospheres, which consist of hydrophobic core and hydrophilic corona on their surfaces, were prepared by the free radical dispersion copolymerization of hydrophobic monomers and hydrophilic macromonomers in a polar solvent. For example, copolymerization of methacrylate-terminated poly (ethylene glycol) (PEG) macromonomers and styrene in ethanol/water mixture gives water dispersible PEG coated nanospheres with a mean diameter around 100-2000 nm. An electron spectroscopy for chemical analysis (ESCA), dynamic light scattering (DLS) and transmission electron microscopy (TEM) observation of ultrathin cross section embedded in a resin supported accumulation of PEG component at the surface of nanospheres. The core-corona type nanospheres can be widely applied to various technological and biomedical applications, because of their possible variety of chemical structure. These nanospheres were utilized as oral drug carriers for peptide drugs physically adsorbed on the nanosphere surfaces, and demonstrated to be useful carrier for incorporating highly water-soluble peptides. Moreover, lectin-immobilized nanospheres could efficiently capture HIV-1 particles and HIV-1-capturing nanospheres may have great potential as a prophylactic vaccine against HIV-1 infection through sexual intercourse.

著者

橘 和夫

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.45, no.9, pp.898-908, 1987-09-01 (Released:2009-11-13)

参考文献数

48

被引用文献数

1 2

---

Two classes of shark repellent factors have been isolated, guided by their ichthyotoxicity, from the defense secretions of two species of soles. One class comprises series of steroid monoglycosides, namely, pavoninins from a western Pacific species, Pardachirus pavoninus, and mosesins from the other in the Red Sea known as Moses sole, P. marmoratus. The other class consists of a series of surfactant peptides of 33 amino acid residues, pardaxins. This account deals with structure elucidation of these factors, where emphasis is put on the process from inference of chemical structures by spectroscopic and other customary techniques to their establishment by design of unconventional but firmly corroborative experiments. Diverse bioactivity of these factors is also discussed based on rationale with their amphiphilic structures, which are destined to interact with biological lipid bilayer membranes.

著者

鈴木 教之

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.65, no.4, pp.347-357, 2007-04-01 (Released:2010-10-20)

参考文献数

92

被引用文献数

10 13

---

It is generally known that small cyclic alkynes such as cyclopentyne is extremely reactive and unstable. Therefore it has been believed impossible to isolate cyclopentyne compounds.We recently reported that low-valent group 4 metallocenes reacted with 1, 2, 3-butatrienes to give 1-metallacyclopent-3-yne complexes and that resulted compounds are surprisingly stable and isolable. We succeeded in determination of their molecular structures by X-ray diffraction analyses, and showed that these are five-membered cyclic alkynes, while π, π-interaction of butatriene was also suggested. In this review, the preparation, structure and reactivity of these 1-metallacyclopent-3-yne compounds are described.The 1-zirconacyclopent-3-yne complexes reacted with another 'zirconocene' to form bimetallic complexes in which the cyclic alkyne coordinated to the other zirconocene moiety, indicating that the zirconacyclopentyne behaved as an alkyne. Seven-membered cyclic alkynes were also prepared from 1, 2, 3-butatriene and a zirconocene-alkyne compound. Protonolysis and subsequent nucleophilic attack to aldehyde gave allenyl or dienyl alcohol depending on proton source.

著者

若宮 淳志

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.64, no.12, pp.1304-1305, 2006-12-01 (Released:2010-10-20)

参考文献数

10

被引用文献数

1

---

This mini review focuses on the developments of Ir-catalyzed direct borylation of arenes via C-H activation. The regioselectivity of the borylation is mainly controlled by the steric factors. The regioselective C-H bond activation/functionalization can provide the borylated arenes which are otherwise difficult to synthesize. Recent applications of the borylation to polycyclic aromatic hydrocarbons and porphyrins are briefly described.

著者

久枝 良雄 嶌越 恒

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.63, no.8, pp.780-790, 2005-08-01 (Released:2009-11-13)

参考文献数

27

被引用文献数

3 3

---

Vitamin B12-dependent enzymes, involving the cobalt species as a catalytic center, mediate various molecular transformations in vivo. In order to use vitamin B12 derivatives (cobalamins) as green catalysts, various studies have been carried out such as a chemical modification of cobalamin or the fixation of B12 derivative on electrodes.The Co (I) species of vitamin B12 derivative is widely known as a supernucleophile that forms an alkylated complex by reaction with an alkyl halide. Such reaction is efficient for dehalogenation of various organic halides. Therefore, vitamin B12 derivatives can be used as catalysts for reductive degradation of organic pollutant such as DDT. In addition, the alkylated complex is a useful reagent for forming radical species as the cobalt-carbon bond is readily cleaved homolytically by photolysis or electrolysis. Therefore, the application of the alkylated complex to organic synthesis is quite interesting from the viewpoint of a radical-forming reagent. This review article summarizes recent progress in homogeneous and heterogeneous catalytic reactions mediated by vitamin B12 derivatives.

著者

坂口 亘弘

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.40, no.12, pp.1204-1205, 1982-12-01 (Released:2009-11-13)

著者

吉川 彰一 野村 正勝 森田 幸男

出版者

The Society of Synthetic Organic Chemistry, Japan

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.34, no.1, pp.36-40, 1976-01-01 (Released:2009-11-13)

参考文献数

14

被引用文献数

3 3

---

ベンゼンとアセトニトリルとの高周波放電反応を行った。液体窒素トラップからえた液状成分の分析からアセトニトリルやベンゼンの単独放電反応でえられる特徴的な生成物の他にベンゾニトリル.ベンジルシアニド, o, m, p-トルニトリルやo, m, p-ジシアノベンゼンが生成していることを認めた。アセトニトリルの単独放電反応ではプロピオニトリル, ブチロニトリル, クロトニトリル, マロノニトリル, スクシノニトリル, グルタロニトリルなどが生成し, この他にテトラシアノエチレンが生成しているのが放電反応物のESRスペクトルから推定された。PBNをラジカル補捉剤として使用したベンゼンの高周波放電反応における活性種のトラップ実験ではベンジルラジカルが生成しているのがESRスペクトルから推定された。