著者
増田 毅
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会誌ATOMOΣ (ISSN:18822606)
巻号頁・発行日
vol.63, no.10, pp.718-722, 2021 (Released:2021-10-10)
参考文献数
7

トリチウム摂取に対する線量評価のためには,その体内動態を明らかにする必要がある。ICRPは,公衆の線量係数を求める際に,トリチウムの体内動態を表す単純な2コンパートメント・モデルを用いてきた。ただし,2016年に作業者の線量係数を求める際には,その体内動態モデルをより複雑なものへ改訂している。これにより作業者の線量係数は従来よりも安全寄りの大きな値となっている。これは脂肪組織を含むと考えられる長半減期成分をモデルに取り入れたためである。
著者
増田 毅 加我 君孝
出版者
一般社団法人 日本めまい平衡医学会
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.71, no.4, pp.270-275, 2012 (Released:2012-10-01)
参考文献数
4
被引用文献数
2

Children with inner ear anomalies resulting in severe hearing impairment may show deficits in head control and independent walking. In the present study we examined the vestibular function in children with bilateral inner ear anomalies using a rotation test, and investigated the impact of the anomalies on motor development. Children with the Michel anomaly, which is characterized by a lack of inner ear differentiation bilaterally, are markedly slow in developing head control and independent walking. As muscle tonus is increased with the myelinization of motor neurons, independent walking becomes possible. On the other hand, children with severe inner ear anomalies, such as bilateral common cavity deformity and incomplete partition type I (Mondini deformity), show vestibular ocular reflex by the rotation test as they age, and normal independent walking and running become possible. These results demonstrate that, although children with inner ear anomalies may be slow in motor development in their infancy, their motor function increases to a normal level as they grow.
著者
岸田 杏子 野村 泰之 地家 真紀 御子柴 郁夫 岸野 明洋 木村 優介 三浦 正稔 戸井 輝夫 増田 毅 鴫原 俊太郎 大島 猛史
出版者
一般社団法人 日本めまい平衡医学会
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.78, no.3, pp.157-163, 2019-06-30 (Released:2019-08-02)
参考文献数
15
被引用文献数
1 1

Purpose: This present study was aimed at evaluating the effects of our original teaching method called “Bang Bang, Hu, Kacha” on the learning efficiency. Methods: We invented this method, which involves hand modulation and vocalization of words, for medical students to enable them to easily understand and memorize the anatomy of the inner ear and vestibular organs. We evaluated its effectiveness based on self-completed questionnaires by the students. Results: The results suggested that the comprehension level of the 30 medical students of the anatomy of the inner ear organs, especially the positional relationships of the semicircular canals and cochlea improved dramatically after they underwent training using this methodology. The medical students assigned high scores to this relational hand modulation method. Conclusion: This “Bang Bang, Hu, Kacha” method seemed to be a very useful for medical education, and allowed easy comprehension and memorization of the inner ear and vestibular anatomical structures.
著者
増田 毅 鴫原 俊太郎 野村 泰之 齋藤 雄一郎 鴫原 じゅん子 肥田 和恵 辻 賢三 池田 稔
出版者
一般社団法人 日本めまい平衡医学会
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.67, no.2, pp.121-129, 2008 (Released:2008-05-29)
参考文献数
18

Brainstem disorders are often characterized by abnormal eye movements, however, the type of abnormal movements vary depending on the localization and severity of the damage. Here, we report a case of pontine hemorrhage who exhibited horizontal conjugate gaze palsy and disorder of speech discrimination. The 34-year-old man presented with eye pain and dull feeling malaise?, disorder of speech articulation and torpor paralysis ?? of the left side of the body of sudden onset, that developed while he was driving a car. Clinical examination revealed horizontal conjugate gaze palsy, both rightward and leftward, while vertical gaze and convergence were normal. Although the pure-tone audiogram and DPOAE were within normal range, ABR showed prolongation of latency, and reduction of speech discrimination was recognized. MRI revealed evidence of hematoma and edema extending from the mid-dorsal aspect to the right side of the pons. Based on the findings, the patient was diagnosed to have pontine hemorrhage due to hypertension affecting the right facial nerve nucleus, right pyramidal tract, bilateral abducens nuclei, MLF, PPRF and the auditory neural pathway. Although the symptoms of pyramidal tract and auditory disorder resolved by day 19 when he was?? moved to another hospital, the other neurological symptoms were persistent.
著者
早川 正道 増田 毅 比嘉 功 小山 雄三 秦野 直 小田 正美 大澤 炯
出版者
社団法人日本泌尿器科学会
雑誌
日本泌尿器科學會雜誌 (ISSN:00215287)
巻号頁・発行日
vol.80, no.1, pp.28-34, 1989-01-20
被引用文献数
1

我々は3例の進行性腎癌患者に対して,2つの異なったtypeのLAK細胞の分割動注とrIL-2の全身投与を併用した養子免疫療法を行ったので,その効果について報告する.リンパ球分離を週1回行い,ついでPercollを用いた密度勾配遠心法でリンパ球を2つのサブタイプに分け,おのおのをrIL-2と共に培養してLAK細胞を誘導した.転移巣の栄養血管を介してLAK細胞を週2回動注した.3例中1例において,上臀動脈を介してLAK細胞を3ヵ月間動注することにより腸骨転移巣が明らかに消失した.また腰動脈へのLAK細胞動注により,腸腰筋と傍大動脈リンパ節転移の消失および腰椎転移巣の縮小が得られた1例を経験した.他の1例では,脳転移に対して内頚動脈よりLAK細胞を動注したが,脳浮腫が増悪し中止となった.LAK細胞の動注療法は,転移性腎癌の治療に有用であり,今後とも期待される方法と考えられた.