著者
鈴木 誠 宮崎 崇
出版者
The Japan Society of Calorimetry and Thermal Analysis
雑誌
熱測定 (ISSN:03862615)
巻号頁・発行日
vol.34, no.5, pp.244-250, 2007-11-15 (Released:2009-09-07)
参考文献数
25

高分解マイクロ波誘電スペクトルを応用した水中の溶質の水和状態を解析する方法を開発した。φスキャン法は溶質周りの水の誘電特性の空間分布に関する情報を提供する。溶質として,アルカリハライド塩,荷電高分子,タンパク質分子等の水和状態を明らかにすることができる。水の構造を破壊する塩として知られるヨウ化アルカリ等はバルクの水より高い誘電緩和周波数の水(ハイパーモバイル水)を周りにもっている。荷電密度の高い高分子やアクチンフイラメントもハイパーモバイル水をもっている。この水は,アクトミオシンの運動機構に関わるなど,生理的な意味でも重要な役割を担っているかもしれない。
著者
鈴木 誠 宮崎 崇
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.47, no.5, pp.295-301, 2007 (Released:2007-09-28)
参考文献数
28
被引用文献数
1

A precision microwave dielectric spectroscopic technique has been developed. This technique enables us to analyze hydration properties of ions, proteins, and other biomolecules. φ-scan method gives an image of the information of spatial distribution of dielectric property of water surrounding protein molecules. Fixed φ analysis gives a direct comparison of hydration properties of different proteins. With this technique we analyzed the state change of F-actin hydration upon binding with myosin, and found that hyper-mobile water (HMW) is induced around F-actin and increased upon binding with myosin S1. Thus, we may obtain further information of collective properties of water surrounding proteins and biomolecules.
著者
賀 馨 宮崎 崇文 辺 美 礼 三浦 研
出版者
日本建築学会
雑誌
日本建築学会計画系論文集 (ISSN:13404210)
巻号頁・発行日
vol.81, no.724, pp.1269-1279, 2016 (Released:2016-06-30)
参考文献数
4
被引用文献数
1

In order to grasp the influence of difference in environment of convalescent rehabilitation wards on the activity of patients, many patients are selected with nearly the same Functional Independence Measure (FIM) scores from two different wards (Ward S and Ward H). In Ward S, which was mainly adopts by consolidate with private sickrooms, unit-type space design. In Ward H, adopts by traditional, multiple-bed sickrooms designing. The activity of these patients in the two wards was measured and compared using the Activity Recorders (ARs). The findings obtained in this study showed that the space and facility design of wards would affect how patients spend their time when they are out of their private rehabilitation times. Compared Ward S to Ward H, there was a difference in the amount of time per stay in the sickrooms. In Ward S, the length of time per stay was longer than that in Ward H. Therefore, indicating that the private sickrooms were more stable places of stay than the traditional and multiple-bed sickrooms. The different space design of Ward S and Ward H may affect the daily walking behavior of patients. However, this investigated result showed that there is almost no difference in number of daily walking steps for patients between Ward S and Ward H. For patients’ exercise intensity of Ward S and Ward H, this study indicated that Ward S is more effective than Ward H in terms of generating patient’s activity when they are not in their private rehabilitation times. In summary, we obtained these findings in this study regarding the two convalescent rehabilitation wards run by the same corporation. There is no great difference in the time ratio of programs provided by the two hospitals for their patients. There is no great difference in terms of the number of daily walking steps for patients between Ward S and Ward H in this investigation study. However, the different of space design affects the exercise intensity. Generally, there may be prompted activities which will increaser the amount of activities of patients for the private sickrooms in the convalescent rehabilitation wards. In our investigation study stage, both wards investigated in this study are pioneers of rehabilitation, and even Ward H, which has a traditional space design, has devised various ways such as by creating a variety of shared space to stay. Therefore, we cannot rule out the possibility that there would be greater differences between the two wards, unless the traditional rehabilitation wards (Ward H) has no attractive with facilities in public space, or has the same facilities with sufficient space of sickrooms as Ward S.